T-집단에서 피이드백유무에 따른 회기별 신뢰행동의 변화

최혜란,설기문 東亞大學校 學生生活硏究所 1998 學生硏究 Vol.17 No.-

The Purpose of this study was to research changes in trusting behavior in T-group counseling. The subjects of this study were 40 students of K and D unversities in the city of Pusan, who were divided into 4 groups which experienced 18 hours of group counseling. There were 18 male and 22 female students. The instruments of this study were "Expectation About Counseling" (Park, 1985), "Group Behaviour Questionnaire", and "Trust Diagram". At the end of each session the trusting behaviour was immediately measured by the filling out of the self-perception and other~perception assessment forms, and the writing out of the verbarim record of the proceedings which had been recorded during group sessions. From the results and discussions of this research, the following conclusions were derived. 1. The trusting behaviour of members in the T-group counseling increases according to group sessions. In other words, trusting behaviour develops from the beginning of the group. 2. The trusting behaviour of group members doesn't change significantly according to feedback. The growth of trusting behaviour increases as the sessions progress whether there is feedback or not. In addition, feedback does no have may effect on the change in trusting behaviour. 3. The verbatum record of the proceeding of the counseling sessions shows that group trusting behaviour significantly increases after the second session. Therefore, group leaders should put into practice group activities based on mutual confidence among the group members' development of trusting behavior of group members in T-group counseling is not significantly affected by the level of the members.

보리순의 영양성분 조성

서혜지,최용민,김상천,이준수,이기택,정명근,천지연,황진봉,남진식,서우덕,황영,김행란,김세나 忠北大學校 農業科學硏究所 2015 農業科學硏究 Vol.31 No.2

갈락토오스혈증에 대한 신생아 선별검사의 사용 시약 및 검체 보관에 따른 영향

최태윤,윤혜란 德成女子大學校 藥學硏究所 2007 藥學論文誌 Vol.18 No.-

Classic galactosemia is caused by impaired galactose-1-phosphate uridyltransferase (GALT EC 2.7.712). If discovered and treated within the first days of life, the acute problems of hepatocellular damage, sepsis, and death are prevented. However, chronic problems such as ataxia, tremor, dyspraxic speech, and ovarian failure may occur. The study was devised to determine whether galactosemia assay method, period of specimen storage, and reagent from different commercial company used affect result of the assay for screening newborns After different concentration level of in-house made galactose was spotted onto control blood specimen it was distributed to the 15 clinical testing laboratories, galactose assay results were received by mail. Correlation coefficient of inter-laboratory and between-laboratory was analyzed depending on period of specimen storage. 6 laboratories was used reagent from ICN, 8 from BioRad, and 1 from Perkin Elmer for galactose testing. For normal reference range from ICN was less than 8, 10, or 12 mg/dL, from BioRad was less than 8, 11, 12 or 13 mg/dL, from Perkin Elmer was less than 10 mg/dL. In case of enzyme colourimetric method, inter-laboratories correlation coefficient was 14 % on the concentration of 1.7 mg/dL, 9 % on the concentration of 2.7 mg/dL, 12 % on the concentration of 4.1 mg/dL, 9 % on the concentration of 7.7 mg/dL, 3 % on the concentration of 14.1 mg/dL, 9 % on the concentration of 34.0 mg/dL for normal negative control specimen, and 10-16% for positive control specimen. After 1 year of storage in refregerator, repeating testing showed within 20 % difference of correlation coefficient, however, results did not show significant difference in both statistics and diagnosis. As a result of our study, each laboratory using different reagent and different assay method ought to determine it's own reference range, is necessary to store newborn screening specimen for 2 years in the refregerator.

갈락토오스혈증 선별검사 양성인 신생아에 대한 정밀검사 결과 분석

최태윤,윤혜란 덕성여자대학교 약학연구소 2010 藥學論文誌 Vol.21 No.-

Background & object : Generally, blood spots of newborn have been sent to the 2n d institution for differential confirmatory test, who showed positive through newborn screening for galactosemia. So far no report on the investigative analyses on confirmatory test results of positive Galactosemia results of newborn blood spots, who have been born in General Hospital. We have investigated the proportion of blood spotsamples that gave positive screen results of newborn blood spots born in Soonchynhyang University Hospital. Methods: We investigated and analyzed through examining medical records of newborns who were born or transferred in Soonchunhyang University Hospital in 2009. Newborn born blood spots obtained were from what was transferred to our Hospital for confirmatory tests or from what was visited to our Hospital for the total galactose, free galactose, galactose-1-phosphate, and Beutler tests. Results : Out of 252 newborns who received secondary confirmatory tests, the newborn blood spots who showed abnormal was as follows; 66 (26.2%) for total galactose, 10 (4.0%) for free galactose, 32 (12.7%) for galactose-1-phosphate and, 0 for Beutler tests. Among 96 newborns who have seen attending physician 18 (19.1 %) showed abnormal, and finally 5 (2.0%) was diagnosed as Galactosemia and 15 was transient Galactosemia. Out of 18 newborns who have been transferred to secondary confirmatory test 3 have been diagnosed as Galactosemia. Finally five (2.0%) was diagnosed as Galac tosemia out of 252 born at Soonchunhyang University Hospital in 2009. From these results we expect there might be more than 7 newborns with Galactosemia, though 7 Galactosemia newborn patients have already been registered at community health center. Conclusions : For the prevention of mental retardation and effective therapy over Galactosemia, secondary confirmatory test ought to be performed right away if the result of newborn screening for Galactosemia is positive. 갈락토오스혈증은 갈락토오스 분해효소의 결핍으로 인하여 섭취한 갈락토오스를 우리 몸에서 에너지 원으로 이용되는 포도당으로 바꾸지 못하여 체내에 갈락토오스가 축적되는 유전성 질환으로 신생아 시기에 치료하지 않으면 발육부전 및 정신지체가 발생 하고 심한 경우 사망하기도 한다. 신생아 때 발견하여 치료하면 정신지체를 예방할 수 있는 유전성 대사질환에 대한 신생아 선별검사가 1985년 국내에 처음 도입된 이후 갈락토오스혈증에 대한 신생아 선별검사가 2006년부터 정부 지원사업으로 채택되어 모든 신생아를 대상으로 무료로 실시되고 있다. 갈락토오스혈증에 대한 선생아 선별검사가 시작된 이후 양성자들에 대한 확인검사를 통하여 갈락토오스혈증 환자가 진단되고 있지만 아직까지 우리나라에서의 발생빈도는 정확히 알 수 없다. 신생아 선별검사에서 갈락토오스혈중 양성인 신생아들은 확인검사 기관에서 정밀검사를 받지만 검밀검사에서 진단된 환아가 얼마나 되는지 정확히 알 수 없고, 진단된 환아 중 몇 명이 보건소에 동록되는지 알 수 없다. 확인검사를 통하여 진단된 환아 중 보건소에 사후관리자로 등록된 환자를 근거로 산출한 2006부터 2009년까지 4년간 갈락토오스혈증의 발생빈도는 51,419명당 1 명이다. 최태윤 등은 2005년도 신생아 선별검사결과를 근거로 산출한 갈락토오스혈증 발생 빈도가 39,314명당 1명으로 보고하였다. 저자들은 갈락토오스혈증에 대한 신생아 선별검사에서 양성인 신생아 중 확인검사를 받기 위하여 정밀검사 기관으로 내원한 신생아들 대상으로 확인검사 결과를 실시하고 그 결과를 분석하여 보고하는 바이다.

노인환자 마취에 대한 임상적 고찰

최영석,신정순,채병국,오혜란 대한마취과학회 1988 Korean Journal of Anesthesiology Vol.21 No.4

In contrast to younger patients, geriatric patients are generally considered to be poor risk for anesthesia and surgery and greater care should be taken in anesthetic management, because many have chronic systemic diseases in addition to a decrease in physiologic function. To evaluate geriatric anesthetic experiences, we reviewed clinical recoreds of 1,062 patients aged over 65 out of 21,656 surgical cases performed at Korea University Hye-Wha Hospital from January 1980 to December 1986. THe case were analysed according to age, sex, department, preoperative physical status, anesthetic techniques and agents, duration of anesthesia, operation site, length of hospital stay, laboratory data (Chest X-ray, EKG), associated diseases, postoperative complications and mortality. The results are as follows: 1) Of the 1,062 geriatric surgical patients, 516 cases (48.6%) were 65∼69 years of age. 2) The number of geriatric surgical cases was 1,062, of which 672 (63.3%) were male and 390 (36.7%) were female. 3) Most surgical cases were general surgery (401 cases, 37.8%). 4) The rate of elective and emergency surgery was 78.0% (829 cases) and 22.0% (233 cases), respectively. The ratio of insurance patients (737 cases, 69.4%) versus noninsurance patients (325 cases, 30.6%) was approximately 2:1. 5) The number of general anesthesia cases was 777(73.2%), spinal anesthesia, 244 (23.0%), epidural anesthesia, 21 (2.0%), and brachial plexus block, 5 (0.5%). The anesthetics were thalamonal and meperidine hydrochloride (238 cases, 22.4%), halothane (204 cases, 19.2%) and tertacaine (244 cases, 23.0%). 6) The duration of anesthesia was within 1 hour in 88 cses (8.3%), 1∼2 hours in 421 cases (39.6%), and 2∼3 hours in 291 cases (27.4%). 7) The number of lower abdominal surgery cases was 197(46.8%) and the number of upper abdominal surgery cases was 188(17.7%). 8) Preoperative laboratory findings were as follows: The findings of preoperative chest X-rays revelaed that 219 case (21.4%) were within normal mits, 182 cases (17.8%) had hypertensive heart, and 208 cases (20.4%) had atherosclerosis. The EKG, which was done on 90.8% of the patients, reveled that 333 cases (34.5%) were within normal limits, 77 case(8.0%) showed left ventricular hypertrophy, 65 case (6.7%) showed sinus bradycardia, and 27 cases (2.8%) showed myocardial ischemia. 9) Hypertension (88 cases, 49.4%) was the most commonly associated disease. 10) The total number of postoperative complication case was 73(6.9%). Seventeen cases showed wound infection and delayed skin closure, 19 cases showed pneumonia, and 7 case showed atelectasis. 11) The total number of postoperative deaths was 18 cases (1.7%).

한국판 자아실현차원검사(POD)의 타당화 연구

설기문,최혜란 東亞大學校 學生生活硏究所 1996 學生硏究 Vol.20 No.-

Inhibition of -glucosidase and -amylase by stearic α α acid isolated from Tetragonia tetragonioides

Hye Jung Choi,Min Jung Hwang,Mi Ran Park,Seung Hee Woo,Dong Wan Kim,Ja Young Moon,Young Whan Choi,Jum Soon Kang,Woo Hong Joo 한국생물공학회 2008 한국생물공학회 학술대회 Vol.2008 No.4

Antiobesity effects of Green tea kombucha (GTK) and Jack been kombucha (JBK) on high-fat diet induced C57BL/6 mice

Hye Ran Choi,Su Jung Lee,Tae Ho Ryu 한국실험동물학회 2023 한국실험동물학회 학술발표대회 논문집 Vol.2023 No.2

Anti-Diabetic Activity of Unripe Black Raspberry Extract in db/db Mice

Hye Ran CHOI,Jung-Hyun LEE,Su Jung LEE,Min Jung LEE,Yong Jong KO,Hee Kwon LEE,Jong Tae CHUNG,Tae-Bum LEE 한국생물공학회 2013 한국생물공학회 학술대회 Vol.2013 No.10

Effects of color barleys fermentation on physicochemical properties, antioxidant activities and adipocyte differentiation

Hye Ran Choi,Su Jung Lee,Tae Ho Ryu,Jong Hyuk Park 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

This study was carried out to investigate the changes in physicochemical properties, antioxidant activities and adipocyte differentiation of color (five colors, purple and black) barleys occurred during lactic acid bacteria fermentation. Color barleys were fermented at 30°C for 24 hours using combined lactic acid bacteria, and then pH, total acidities, total polypenols, total flavonoids, DPPH and ABTS radical scavenging activities were measured. Total acidities of lactic acid bacteria-fermented color barleys increased while pH values decreased. Contents of total polyphenol of color barleys were significantly increased, also ABTS radical scavenging activities were elevated after fermentation. The anti-obesity effects of color barleys fermentation were investigated by measuring Oil Red O staining in 3T3-L1 adipocytes. The staining results showed that significantly reduced lipid accumulation in cells. These results suggest that color barleys fermented with lactic acid bacteria has potential as functional anti-obesity food material.