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Response of Odontoblast to the Bio-Calcium Phosphate Cement
Kim, Jin-Woo,Kim, Sung-Won,Kim, Gyoo-Cheon,Kim, Yong-Deok,Kim, Cheol-Hun,Kim, Bok-Joo,Kim, Uk-Kyu Korean Association of Maxillofacial Plastic and Re 2011 Maxillofacial Plastic Reconstructive Surgery Vol.33 No.4
Purpose: If the tooth structure is damaged, then it is impossible to regenerate the tooth. The materials used to restore the tooth structure are not related to the composition of the tooth. The materials used to restore the structure can't replace the natural tooth because they just fill the defective structure. Calcium phosphate cement remineralizes the dentin and almost replaces the natural tooth, but there are some disadvantages. We conducted basic tests with Biomimetic CPC (Bio-CPC) to make sure of the possibility of the biomaterial to remineralize the defective tooth structure. Methods: In this study, the bioactivity and biocompatibility of Bio-CPC were evaluated for its potential value as the bio-material for regeneration of damaged tooth structure by conducting a cell toxicity assay (WST-1 assay), a cytokinesis-block micronucleus assay, a chromosomal aberration test, total RNA extraction and RT-PCR on MDPC-23 mouse odontoblast-like cells. Results: The in vitro cytotoxicity test showed that the Bio-CPC was fairly cytocompatible for the MDPC-23 mouse odontoblast-like cells. Conclusion: Bio-CPC has a possibility to be a new biomaterial and further study of Bio-CPC is needed.
Mechanical Properties of Silica Nanoparticle Reinforced poly(ethylene 2, 6-naphthalate)
Kim, Seong-Hun,Ahn, Seon-Hoon,Kim, Byoung-Chul,Shim, Kwang-Bo,Cho, Bong-Gyoo The Polymer Society of Korea 2004 Macromolecular Research Vol.12 No.3
We added surface-modified silica nanoparticles to poly(ethylene 2,6-naphthalate) (PEN) to investigate their effect on the mechanical properties on the PEN nanocomposite material. The torque and total torque values of the composites decreased in the silica nanoparticle composites. The tensile modulus of the composites reinforced with unmodified silica nanoparticles increased upon increasing the silica content, while the tensile strength and elongation decreased accordingly. In contrast, stearic acid-modified, silica nanoparticle reinforced PEN composites exhibited an increase in elongation and a decrease in tensile modulus upon addition of the silica nanoparticles because the stearic acid that had adsorbed onto the surface of the silica nanoparticle in multilayers could act as a plasticizer during melt compounding. Stearic acid modification had a small effect on the crystallization behavior of the composites. We calculated theoretical values of the tensile modulus using the Einstein, Kerner, and Nielsen equations and compared these values with the experimental data obtained from the composites. The parameters calculated using the Nielsen equation and the Nicolais- Narkis model revealed that the interfacial adhesion between silica nanoparticles and the PEN matrix could be improved.
Yun Ho Kim,Han Kyul Park,Na Rae Choi,Seong Won Kim,Gyoo Cheon Kim,Dae Seok Hwang,Yong Deok Kim,Sang Hun Shin,Uk Kyu Kim 대한구강악안면외과학회 2017 대한구강악안면외과학회지 Vol.43 No.1
Objectives: Bisphosphonate is the primary cause of bisphosphonate-related osteonecrosis of the jaw (BRONJ). Bisphosphonates are eliminated from the human body by the kidneys. It is anticipated that bisphosphonate levels in the body will increase if the kidney is in a weak state or if there is systemic disease that affects kidney function. The aim of this study was to analyze the relevance of renal function in the severity of BRONJ. Materials and Methods: Ninety-three patients diagnosed with BRONJ in Pusan National University Dental Hospital from January 2012 to December 2014 were included in this study. All patients underwent a clinical exam, radiographs, and serologic lab test, including urine analysis. The patient’s medical history was also taken, including the type of bisphosphonate drug, the duration of administration and drug holiday, route of administration, and other systemic diseases. In accordance with the guidelines of the 2009 position paper of American Association of Oral and Maxillofacial Surgeons, the BRONJ stage was divided into 4 groups, from stage 0 to 3, according to the severity of disease. IBM SPSS Statistics version 21.0 (IBM Co., USA) was used to perform regression analysis with a 0.05% significance level. Results: BRONJ stage and renal factor (estimated glomerular filtration rate) showed a moderate statistically significant correlation. In the group with higher BRONJ stage, the creatinine level was higher, but the increase was not statistically significant. Other factors showed no significant correlation with BRONJ stage. There was a high statistically significant correlation between BRONJ stage and ‘responder group’ and ‘non-responder group,’ but there was no significant difference with the ‘worsened group.’ In addition, the age of the patients was a relative factor with BRONJ stage. Conclusion: With older age and lower renal function, BRONJ is more severe, and there may be a decrease in patient response to treatment.
Design of a Pedestal Part for the Marine Surveillance Night Vision System
Jung-Keun Kim,Jong-Min Kim,Ki-Rang Park,Se-Hun Song,Seung-Hun Baek,Jong-Ok Baek,Yun-Hyung Lee,Seung-Wook Hwang,Gang-Gyoo Jin 한국항해항만학회 2006 한국항해항만학회 학술대회논문집 Vol.2006 No.-
This paper presents the design of a surveillance night vision system for marine ships. Both a hardware system and software modules for tracking control are developed. In order to control each control axis with compensation for ship motion, the two-degree of freedom(TDF) PID controller is designed and its parameters are tuned using a real-coded genetic algorithm(RCGA). Simulation demonstrates the effectiveness of the proposed system.