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( Bo Bin Cha ),( Kyu Yeon Kim ),( Jin Seop Kim ),( Yeon Gu Choi ),( Gyoo Huh ),( Hyeon Jeong Park ),( Heun Joo Lee ),( Young Jun Choi ),( Won-serk Kim ),( Ga-young Lee ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.-
Background: Relative tumor density (RTD) has been a standard method to compare skin cancer distribution by anatomical sites. RTD is a flawless tool to analyze soft tissue sarcoma (STS), a group of heterogenous malignant neoplasms with whole-body distribution. Objectives: This study aims to analyze RTD of STS in Korean cohort and provide a solid foundation to approach STS from different body sites. Methods: The biopsy data of 40 patients and a total of 41 sarcoma lesions was analyzed. RTD was calculated by dividing the proportion of tumors at a defined anatomical site by the mean proportion of the skin surface area. Body was classified into four anatomical sites of head and neck, trunk, upper limbs, and lower limbs. Results: Mean age of 26 men and 14 women was 64 years. The most commonly diagnosed sites of 41 lesions were lower limbs (n=16, 39.0 %) and trunk (n=12, 29.3 %). The sites with the highest RTD were head and neck (n=11, 2.98) and lower limbs (n=16, 0.98). The most common tumor in head and neck area was cutaneous angiosarcoma (n=7, 63.6 %). In terms of tumor type, Kaposi’s sarcoma (n=14, 34.1 %) was the most common, followed by dermatofibrosarcoma protuberans (n=12, 29.3 %). Conclusion: The concept of RTD paves the way to approach soft tissue sarcomas which show histological and topographical complexity.
( Gyoo Huh ),( Kyu Yeon Kim ),( Bo Bin Cha ),( Jin Seop Kim ),( Yeon Gu Choi ),( Hyeon Jeong Park ),( Heun Joo Lee ),( Young Jun Choi ),( Won-serk Kim ),( Ga-young Lee ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.-
Background: Laser treatment for dermal melanocytosis is often unsatisfactory. The picosecond-domain, 755-nm alexandrite laser has been proposed as a promising therapeutic option in Asian. Objectives: We aimed to evaluate the efficacy and safety of a 755-nm picosecond alexandrite laser for the treatment of dermal melanocytosis. Methods: This prospective open-labeled trial comprised 25 Korean subjects with dermal melanocytosis. Subjects received three laser treatments at 8-week intervals. Parameters were set at 700-picosecond pulse width, fluence of 3 J/㎠, 3-mm spot size, and 4 Hz repetition rate and modified to the extents of 10 % depending on the therapeutic response. All were evaluated at every visit and 3 months after the final treatment (28 weeks from the baseline). Melanin index (MI) was measured and two blinded dermatologists rated clinical improvement using physicians’ global assessment (PGA) based on standardized photographs. Patients’ self-assessment and adverse events were also recorded. Results: Mean MI showed significant improvement compared with baseline at week 28 (p<0.001; mean differences of -0.02). On PGA, 50 % (12/24) and 16.7 % (4/24) of subjects were reported at least moderate improvement and marked improvement at week 28, respectively. All the adverse reactions were mild and transient. Conclusion: The 755-nm picosecond alexandrite laser can be an effective and safe treatment option to treat dermal melanocytosis in Asian.
Relative tumor density of soft tissue sarcoma in Korean population: A retrospective analysis
( Bo Bin Cha ),( Kyu Yeon Kim ),( Jin Seop Kim ),( Yeon Gu Choi ),( Gyoo Huh ),( Hyeon Jeong Park ),( Heun Joo Lee ),( Young Jun Choi ),( Won-serk Kim ),( Ga-young Lee ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.1
Background: Relative tumor density (RTD) has been a standard method to compare skin cancer distribution by anatomical sites. RTD is a flawless tool to analyze soft tissue sarcoma (STS), a group of heterogenous malignant neoplasms with whole-body distribution. Objectives: This study aims to analyze RTD of STS in Korean cohort and provide a solid foundation to approach STS from different body sites. Methods: The biopsy data of 40 patients and a total of 41 sarcoma lesions was analyzed. RTD was calculated by dividing the proportion of tumors at a defined anatomical site by the mean proportion of the skin surface area. Body was classified into four anatomical sites of head and neck, trunk, upper limbs, and lower limbs. Results: Mean age of 26 men and 14 women was 64 years. The most commonly diagnosed sites of 41 lesions were lower limbs (n=16, 39.0 %) and trunk (n=12, 29.3 %). The sites with the highest RTD were head and neck (n=11, 2.98) and lower limbs (n=16, 0.98). The most common tumor in head and neck area was cutaneous angiosarcoma (n=7, 63.6 %). In terms of tumor type, Kaposi’s sarcoma (n=14, 34.1 %) was the most common, followed by dermatofibrosarcoma protuberans (n=12, 29.3 %). Conclusion: The concept of RTD paves the way to approach soft tissue sarcomas which show histological and topographical complexity.
( Gyoo Huh ),( Kyu Yeon Kim ),( Bo Bin Cha ),( Jin Seop Kim ),( Yeon Gu Choi ),( Hyeon Jeong Park ),( Heun Joo Lee ),( Young Jun Choi ),( Won-serk Kim ),( Ga-young Lee ) 대한피부과학회 2021 대한피부과학회 학술발표대회집 Vol.73 No.1
Background: Laser treatment for dermal melanocytosis is often unsatisfactory. The picosecond-domain, 755-nm alexandrite laser has been proposed as a promising therapeutic option in Asian. Objectives: We aimed to evaluate the efficacy and safety of a 755-nm picosecond alexandrite laser for the treatment of dermal melanocytosis. Methods: This prospective open-labeled trial comprised 25 Korean subjects with dermal melanocytosis. Subjects received three laser treatments at 8-week intervals. Parameters were set at 700-picosecond pulse width, fluence of 3 J/㎠, 3-mm spot size, and 4 Hz repetition rate and modified to the extents of 10 % depending on the therapeutic response. All were evaluated at every visit and 3 months after the final treatment (28 weeks from the baseline). Melanin index (MI) was measured and two blinded dermatologists rated clinical improvement using physicians’ global assessment (PGA) based on standardized photographs. Patients’ self-assessment and adverse events were also recorded. Results: Mean MI showed significant improvement compared with baseline at week 28 (p<0.001; mean differences of -0.02). On PGA, 50 % (12/24) and 16.7 % (4/24) of subjects were reported at least moderate improvement and marked improvement at week 28, respectively. All the adverse reactions were mild and transient. Conclusion: The 755-nm picosecond alexandrite laser can be an effective and safe treatment option to treat dermal melanocytosis in Asian.