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      • KCI등재

        Mechanical Properties and Microstructure of Polypropylene Fiber Reinforced Cement Mortar Soil

        Bo Ruan,Hui Ding,Jidong Teng,Wei Deng,Shilong Zheng,Chenxi Ruan 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.6

        A series of unconfined compressive strength tests and flexural strength tests are carried out to evaluate the improved effect of polypropylene fiber on the defects of cement mortar soil. The following factors, including the fiber content, cement content, sand content and curing age, are studied to investigate the influences on the mechanical properties and microstructure of the samples. The results show that the unconfined compressive strength (UCS), residual strength and flexural strength of the fiber reinforced cement mortar soil (FRCMS) substantially increase with increasing fiber content. The peak strain and ratio of the flexural-compression strength (Rfcs) of the FRCMS first increase and then decrease with an increase in fiber content,and the optimal fiber content is 3.5%. The brittleness index of the FRCMS is found to be inversely proportional to fiber content. The results suggest that the addition of an appropriate amount of fibers can substantially improve the plasticity and lateral stress capacity of the FRCMS. The strength of the FRCMS improves with the increase in cement content, sand content and curing age within a certain range. The microstructure of the FRCMS are analyzedby scanning electron microscopy (SEM) tests.

      • SCIESCOPUSKCI등재

        DYNAMIC CHARACTERISTICS OF SCALED-DOWN W-BEAMS UNDER IMPACT

        Hui, T.-Y.-J.,Ruan, H.-H.,Yu, T.-X. The Korean Society of Automotive Engineers 2003 International journal of automotive technology Vol.4 No.1

        W-beam guardrail system has been the most popular roadside safety device around the world. Through large plastic deformation and corresponding energy dissipation, a W-beam guardrail system contains and re-directs out-of-control vehicles so as to reduce the impact damage on the vehicle occupants and the vehicles themselves. In this paper, our recent experiments on 1 : 3.75 downscaled W-beam and the beam-post system are reported. The static and impact test results on the load characteristics, the global response and the local cross-sectional distortion are reveled. The effects of three different end-boundary conditions for the beam-only testing are examined. It is found that the load characteristics are much dependent on the combined contribution of the local cross-sectional distortion and the end-supporting conditions. The energy Partitioning between the beam and the supporting Posts in the beam-Post-system testing were also examined. The results showed that the energy dissipation partitioning changed with the input impact energy. Finally, a simple mass-spring model is developed to assess the dynamic response of a W-beam guardrail system in response to an impact loading. The model's prediction agrees well with the experimental results.

      • KCI등재

        Application of O-RADS US combined with MV-Flow to diagnose ovarian-adnexal tumors

        Linlin Ruan,Hui Liu,Hong Xiang,Yongkang Ni,Yuling Feng,Huili Zhou,Mengtong Qi 대한초음파의학회 2024 ULTRASONOGRAPHY Vol.43 No.1

        Purpose: This study aimed to explore the application of Ovarian-Adnexal Reporting and Data System Ultrasound (O-RADS US) combined with MV-Flow (Samsung Medison Co., Ltd.) to diagnose ovarian-adnexal masses.Methods: A total of 112 ovarian-adnexal masses (81 benign and 31 malignant) from 105 consecutive patients were analyzed. The O-RADS US and vascular index from MV-Flow (VI<sup>MV</sup>) were measured and compared with the reference standard. O-RADS US and MV-Flow were tested for consistency.Results: Receiver operating characteristic curves were drawn for O-RADS US, MV-Flow, and their combination. The combined methods had the largest area under the curve (0.955), followed by O-RADS US (0.929) and MV-Flow (0.923). A mass was considered malignant when the O-RADS US classification was 5 and VI<sup>MV</sup> was ≥7.15. With this definition, MV-Flow had the highest sensitivity (87.10%), with consistent findings for the combined diagnostic methods and O-RADS US (83.87%). The specificity of the combined diagnostic methods (93.83%) was higher than that of MV-Flow (91.36%). O-RADS US had the lowest specificity (90.12%). The combined diagnostic methods had the highest coincidence rate (91.07%), and MV-Flow (90.18%) had a significantly higher coincidence rate than O-RADS US (88.39%). Both O-RADS US and MV-Flow showed good consistency among different physicians (former kappa, 0.974; latter intraclass correlation coefficient [ICC], 0.986). MV-Flow had a high consistency for the same physician (ICC, 1).Conclusion: O-RADS US and MV-Flow exhibited good diagnostic efficacy, and their combined diagnostic efficacy was higher than that of each individually. O-RADS US and MV-Flow can improve the diagnosis of benign and malignant ovarian-adnexal masses. Purpose: This study aimed to explore the application of Ovarian-Adnexal Reporting and Data System Ultrasound (O-RADS US) combined with MV-Flow (Samsung Medison Co., Ltd.) to diagnose ovarian-adnexal masses. Methods: A total of 112 ovarian-adnexal masses (81 benign and 31 malignant) from 105 consecutive patients were analyzed. The O-RADS US and vascular index from MV-Flow (VIMV) were measured and compared with the reference standard. O-RADS US and MV-Flow were tested for consistency. Results: Receiver operating characteristic curves were drawn for O-RADS US, MV-Flow, and their combination. The combined methods had the largest area under the curve (0.955), followed by O-RADS US (0.929) and MV-Flow (0.923). A mass was considered malignant when the O-RADS US classification was 5 and VIMV was ≥7.15. With this definition, MV-Flow had the highest sensitivity (87.10%), with consistent findings for the combined diagnostic methods and O-RADS US (83.87%). The specificity of the combined diagnostic methods (93.83%) was higher than that of MV-Flow (91.36%). O-RADS US had the lowest specificity (90.12%). The combined diagnostic methods had the highest coincidence rate (91.07%), and MV-Flow (90.18%) had a significantly higher coincidence rate than O-RADS US (88.39%). Both O-RADS US and MV-Flow showed good consistency among different physicians (former kappa, 0.974; latter intraclass correlation coefficient [ICC], 0.986). MV-Flow had a high consistency for the same physician (ICC, 1). Conclusion: O-RADS US and MV-Flow exhibited good diagnostic efficacy, and their combined diagnostic efficacy was higher than that of each individually. O-RADS US and MV-Flow can improve the diagnosis of benign and malignant ovarian-adnexal masses.

      • Association of Leptin Receptor Lys109Arg and Gln223Arg Polymorphisms with Increased Risk of Clear Cell Renal Cell Carcinoma

        Mu, Hui-Jun,Zou, Jian,Xie, Ping,Xu, Zhuo-Qun,Ruan, Jun,Yang, Shu-Dong,Yin, Ying Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.10

        Background: Although roles of genetic polymorphisms of leptin receptor (LEPR) gene in several cancers have been documented, the association between polymorphisms of LEPR and clear cell renal cell carcinoma (CC-RCC) remains unknown. The aim of this study was to explore any relation. Materials and Methods: The study population consisted of 77 patients with CC-RCC and 161 healthy control subjects. Polymorphism analyses of Lys109Arg and Gln223Arg were performed by direct DNA sequencing and PCR-restriction fragment length polymorphism approaches respectively. Results: Comparisons of allelic and genotypic frequencies in Lys109Arg and Gln223Arg showed no significant difference between the cases and controls. However, when evaluating the combined genotype of Lys109Arg and Gln223Arg, risk with GG/GG was increased (OR=1.85, 95%CI=1.04-3.30) and with GA/GG or GG/GA was decreased (OR=0.07, 95%CI=0.01-0.54; OR and 95%CI of the latter could not be calculated for a value of zero). Furthermore, the G-G haplotype frequency of Lys109Arg and Gln223Arg in the cases was higher (OR=1.68; 95%CI=1.02-2.76). In contrast, the A-G and G-A haplotype frequencies in the cases were lower than those in the controls (OR=0.06; 95%CI=0.01 to 0.47; OR and 95%CI of the latter could not be calculated for a value of zero). In addition, the Lys109Arg A allele was in LD with the Gln223Arg A allele (d'=0.9399) in the CC-RCC subjects, but not in the controls. Conclusions: Our data suggest that the GG/GG combined genotype and G-G haplotype of Lys109Arg and Gln223Arg can act as evaluating factors for CC-RCC risk.

      • KCI등재

        miR156b from Soybean CMS Line Modulates Floral Organ Development

        Xianlong Ding,Hui Ruan,Lifeng Yu,Qiang Li,Qijian Song,Shouping Yang,Junyi Gai 한국식물학회 2020 Journal of Plant Biology Vol.63 No.2

        The miR156 and plant specifc transcription factor SQUAMOSA PROMOTER BINDING PROTEIN-LIKE (SPL) are known for their function regulating plant growth and development. In this study, we identifed 20 GmSPLs which are targeted by gma-miR156b via plant small RNA target and degradome analysis. And we found high transcript levels of gma-miR156b and its targeted GmSPLs in the fower of soybean cytoplasmic male sterility (CMS) line and its maintainer. The gma-miR156b direct cleavage of GmSPL2b and GmSPL9b, and have opposite expression levels during early fower buds development. We observed a high expression level of GUS protein in the anthers of the line with pgma-MIR156b::GUS reporter. Over-expression of the gma-miR156b precursor in Arabidopsis inhibited foral organ development, including reduced anther size and the amount of pollen grains per anther etc. Like miR156-targeted SPL genes, non-targeted GmSPL8s were also down-regulated in early fower bud development of soybean CMS line compared with its maintainer line, which might act in concert with miR156-targeted SPL genes to participate in the foral organ development. Quantitative real time PCR (qRT-PCR) suggested that miR156/SPL modulates foral organ development by regulating the expression of LATERAL ORGAN BOUNDARIES DOMAIN22 (LBD22), LBD36, AGAMOUS-LIKE30 (AGL30) and AGL104. Our fndings will facilitate understanding of the biological functions of miR156/SPL in foral organ development of soybean CMS.

      • KCI등재

        Planning and Execution of Dynamic Whole-body Locomotion for a Wheeled Biped Robot on Uneven Terrain

        Yaxian Xin,Jiuhong Ruan,Yibin Li,Hui Chai,Xuewen Rong 제어·로봇·시스템학회 2024 International Journal of Control, Automation, and Vol.22 No.4

        To improve the adaptability of the wheeled biped robot (WBR) to uneven terrain, firstly an integrated modeling method for wheeled-legs is proposed. The under-actuated part is effectively restrained by defining the interaction force between the WBR and the trunk. The mapping relationship between the wheeled leg’s end force and the joint torques in the balanced state is built. Based on this premise, a control framework that does not rely on external sensors is proposed, and the trunk pose is used as the task space to plan the generalized force output of the wheeled legs and calculate the joint torques. Since the joint space position is not constrained, the leg wheels will be based on the terrain conditions and are adaptively stretched and adjusted back and forth. To further improve the terrain adaptability, a slope estimator and a stabilizer are constructed to deal with the attitude fluctuation caused by the sudden change of terrain. The control framework is proved to verify by simulations and experiment.

      • DYNAMIC CHARACTERISTICS OF SCALED-DOWN W-BEAMS UNDER IMPACT

        T. Y. J. HUI,H. H. RUAN,T. X. YU 한국자동차공학회 2003 International journal of automotive technology Vol.4 No.1

        W-beam guardrail system has been the most popular roadside safety device around the world. Through large plastic deformation and corresponding energy dissipation. a W -beam guardrail system contains and re-directs out-of-control vehicles so as to reduce the impact damage on the vehicle occupants and the vehicles themselves. In this paper. our recent experiments on 1:3.75 downscaled W-beam and the beam-post system are reported. The static and impact test results on the load characteristics. the global response and the local cross-sectional distortion are reveled. The effects of three different end-boundary conditions for the beam-only testing are examined. It is found that the load characteristics are much dependent on the combined contribution of the local cross-sectional distortion and the end-supporting conditions. The energy partitioning between the beam and the supporting posts in the beam-post-system testing were also examined. The results showed that the energy dissipation partitioning changed with the input impact energy. Finally. a simple mass-spring model is developed to assess the dynamic response of a W-beam guardrail system in response to an impact loading. The model's prediction agrees well with the experimental results<br/>

      • KCI등재

        Enhancement of Photoluminescence by Ag Localized Surface Plasmon Resonance for Ultraviolet Detection

        Yanlei Lyu,Jun Ruan,Mingwei Zhao,Ruijin Hong,Hui Lin,Dawei Zhang,Chunxian Tao 한국광학회 2021 Current Optics and Photonics Vol.5 No.1

        For higher sensitivity in ultraviolet (UV) and even vacuum ultraviolet (VUV) detection of siliconbased sensors, a sandwich-structured film sensor based on Ag Localized Surface Plasmon Resonance (LSPR) was designed and fabricated. This film sensor was composed of a Ag nanoparticles (NPs) layer, SiO 2 buffer and fluorescence layer by physical vapour deposition and thermal annealing. By tuning the annealing temperature and adding the SiO 2 layer, the resonance absorption wavelength of Ag NPs matched with the emission wavelength of the fluorescence layer. Due to the strong plasmon resonance coupling and electromagnetic field formed on the surface of Ag NPs, the radiative recombination rate of the luminescent materials and the number of fluorescent molecules in the excited state increased. Therefore, the fluorescent emission intensity of the sandwich-structured film sensor was 1.10–1.58 times at 120–200 nm and 2.17–2.93 times at 240–360 nm that of the single-layer film sensor. A feasible method is provided for improving the detection performance of UV and VUV detectors.

      • KCI등재

        Four new compounds from the bulbs of Lycoris aurea with neuroprotective effects against CoCl2 and H2O2-induced SH-SY5Y cell injuries

        An Jin,Xuelian Xiang,Yun-Yun Zhu,Heng-Yi Yu,Hui-Fang Pi,Peng Zhang,Han-Li Ruan 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.3

        Three new alkaloids, 2a-hydroxy-6-O-n-butyloduline,O-n-butyllycorenine, (-)-N-(chloromethyl)lycoramine(1–3), and a new phenolic compound, ((7S)-7-(4-hydroxyphenyl)-7-hydroxypropyl)-20-methylbenzene-30,60-diol (14), along with ten known alkaloids (4–13), wereisolated from the bulbs of Lycoris aurea collected fromHuaihua County of Hunan Province, China. Their structureswere elucidated by spectroscopic methods includingHRESIMS, UV, IR, and NMR. All the isolated compoundswere tested for their neuroprotective effects against CoCl2and H2O2-induced SH-SY5Y cell death. Compounds 1–7and 10 exhibited significant neuroprotective effects againstCoCl2-induced SH-SY5Y cell injury, while compounds1–5, 7, 10 and 12 showed obvious neuroprotective effectsagainst H2O2-induced SH-SY5Y cell death.

      • SCIESCOPUSKCI등재

        Four new compounds from the bulbs of Lycoris aurea with neuroprotective effects against $CoCl_2$ and $H_2O_2$-induced SH-SY5Y cell injuries

        Jin, An,Li, Xue,Zhu, Yun-Yun,Yu, Heng-Yi,Pi, Hui-Fang,Zhang, Peng,Ruan, Han-Li 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.3

        Three new alkaloids, $2{\alpha}$-hydroxy-6-O-n-butyloduline, O-n-butyllycorenine, (-)-N-(chloromethyl)lycoramine (1-3), and a new phenolic compound, ((7S)-7-(4-hydroxyphenyl)-7-hydroxypropyl)-2'-methylbenzene-3',6'-diol (14), along with ten known alkaloids (4-13), were isolated from the bulbs of Lycoris aurea collected from Huaihua County of Hunan Province, China. Their structures were elucidated by spectroscopic methods including HRESIMS, UV, IR, and NMR. All the isolated compounds were tested for their neuroprotective effects against $CoCl_2$ and $H_2O_2$-induced SH-SY5Y cell death. Compounds 1-7 and 10 exhibited significant neuroprotective effects against $CoCl_2$-induced SH-SY5Y cell injury, while compounds 1-5, 7, 10 and 12 showed obvious neuroprotective effects against $H_2O_2$-induced SH-SY5Y cell death.

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