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The selective melatonin receptor agonism effect of ramelteon is useful for insomnia. Here we wanted to present a refractory chronic migraine case, who had significant improvements in migraine after using ramelteon. The possible mechanism for the ramelteon in the migraine relief might be related to melatonin effects.
The paper presents a direct shape optimization approach that minimizes both boundary stress concentration and peak contact pressure of multi-body contact systems. This approach is centered on the direct shape modification of boundary regions of stress concentration measured by von Mises stresses and contact surfaces measured by contact pressure. Without requiring sensitivity data for shape modification,shape optimization is made directly on nodal positions through an iterative computational scheme. Therefore, this approach is simple to implement using either commercial finite element software or in-house programs. An adjustable weighting factor is used to ensure stable and accelerated convergence in shape optimization. To evaluate the proposed approach, three case problems are presented,and the results show that this direct shape optimization approach can be especially applicable to the design and analysis of multi-body systems where boundary stress concentration and contact pressure distribution are an important consideration.
The purpose of this study is to provide the planning method for improving the building & sales area layout of multi-storied discount store. To achieve the purpose, the five multi-storied discount stores were picked out which were located in new cities of capital region, and which were investigated through surveying the layouts and questioned targeter. As a result, conclusions were drawn as follows. First, designing the building layout, it is recommended that sales area is not more than three stories. Second, it is strongly recommended that overground sales area, overground parking lot should be equiped and the moving walk that connect sales area to parking lot is essential for convenient purchase. Third, when designing the sales area layout, it is recommended that entrance should be united to one and the pattern of check-out stand and entrance in sales area should be 'I-type', and the minimum of main & sub shopping aisles should be 5-5.5m and 2-2.5m as each.
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Sir Lu Xun is a great literati and thinker of China in 20 century. His thought and works have affected to Chinese literature in China until now. In this thesis, contents is divided as 8 parts. The cultural setting of May 4th Cultural Revolution is discussed. It is also discussed that the China has introduced the Western Culture, asserted the spirit of Democracy and Science and criticized the feudalistic family system and ethnical concept on the basis of critic of the Confucian Culture. On this basis, The vision and faith since they have changed their nationality will be described. In the conclusion, it is represented that the limit of the Cultural Revolution denied the whole westernization which are popular in China and its main spirit wouldn't changed.
We began economic theory with a discussion of the validity of the ceteris paribus assumption, for we felt this was the crucial issue in market economy or planned economy. My research was that the ceteris paribus assumption could be applied, due primarily to the common level of postwar economic development and to the existence of a relatively North-South problem. "Agriculture versus industry" is not quite the correct way of putting the problem. Every growth economist agrees that rising per capita income is associated with a greater or smaller degree of movement from the primary sector to the secondary and tertiary sectors. Within the world as a whole, the lower income countries are the primary sector and the higher income countries the industrial sector. What our empirical analysis revealed is the existence of the substantial per capita output, productivity, and consumption gaps for the rural district, where the gaps appear to be wider for consumption than for per capita output and for productivity. Moreover, I found that these gaps do not appear to be narrowing significantly, although there is some contradictory evidence on this point. Throughout the empirical section I was troubled by certain contradictions in the rural district industrial production figures which introduced measurement errors into the aggregate figures. Concerning the priority objective of the country, economic growth, we found roughly equivalent rates of growth of output, industry and social welfare in high-technology period.
Methodological Linear Bayesian can be used to revise the prior probabilities. It is reasoned that the prior probabilities plus any additional information, such as the results of a sample, provide a better basis for a decision than just prior probabilities. A method of linear prediction uses only the first two moments of the distribution of parameters and observations, rather than the complete probability model required of Bayesian techniques. Linear Bayesian method merely converts these subjective judgments into probabilities and using a mathematical format revises an initial estimate and arrives at a set of profit alternatives for the business executive.
What our empirical analysis revealed is the existence of substential per capita output, productivity, and consumption gaps for the rapid growth country, where the gaps appear to the wider for consumption than for per capita output and for productivity. Moreover my try that these gaps do not appear to be narrowing significantly, although there is some contradictory evidence on this point. Throughout the empirical section we were troubled by certain contradictions in the UTC(under-technological country) industrial production figures which introduced measurement erros into the aggregate figures. Concerning the priority objective of the UTC, economic growth we try roughly equivalent rates of growth of output, industry and social welfare in the high-technology period. We were unable to compare the distribution of income on a comprehensive basis including both wage and wealth income and including all social groups. Rather, my analysis was limited to the distribution of income among UTC. This comparison indioadet a slightly less unequal distribution of wage income in the UTC but failed to reveal dramatic differences in the distribution of income. Finally, I argued that the apparently greater stability of the LGC(low-growth country) economy in terms of growth, price stability, and employment has led to certain efficiency and quality costs, but that these costs have been kept within manageable limits. On the other hand, we will recognize the fact that the LGC economy also has been among the most stable of the major 21st century's industrial-society.
The problem of whether we can determine the structural equations, given knowledge of the reduced form, is called the identification problem. The consideration of the identification problem comes before consideration of the estimation problem. After the identification problem has been explicitly considered, we can then proceed to choose between alternative estimation techniques. An equation is identified if it is possible to obtain values of the parameters from the reduced-form equation system. An equation is exactly identified if a unique parameter value exists and over identified if more than one value is obtainable for some parameters. In this research the concepts of identifiability and of exact and consistent estimability for econometric models are introduced in a rather general framework, and the relations between these concepts are investigated. As a main result we obtain conditions under which identifiability and consistency are equivalent almost everywhere. The identification problem is understandably more complicated when the distribution of the disturbances is incompletely specified.
The purpose of this examination was to find out the relationship among secondary school learners' self-efficacy, instructional motivation and school life-related coping. And in order to achieve the purpose of this examination sampled middle/high school learners in Seoul and other areas. The instruments used for the data collection were 「Self-efficacy Scale」 (Kim, A-Young, 1997), 「School Learning Motivation」 (Kim, Yong-Rae, 2000) and 「School Adjustment Scale」 (Kim, Yong-Rae, 2000). The collected data analysis were performed using SPSS/WIN(11.0V) program, and analysis Mean score(M), Standard Deviation(SD), Zero Order Correlation(r) and Multi-Regression Analysis All statistic values were tested by t-test and F-test in the significant level of p<05. And as for the major findings of this examination, 'self-efficacy', 'instructional motivation' and 'school life-related coping' were significantly positive correlation. And 'self-efficacy' and 'instructional motivation' were significantly positive influences on Korea secondary school learners' 'school life-related coping' respectively.
In other to investigate α-1, 3 glucanase from microorganisms for hydrolysis of dental caries, S. muatns was immobilized by cubes of 28% polycrylamide and coated with same polyacrylamide. The insoluble glucan obtained 1.13g per one liter in TH medium with 5% sucrose by PA immobilization of S. muatns, which was very pure by IR and TLC analysis. α-1, 3 glucanase produced by of the Strptomyces SW-522, was developed by treatment with 5% EMS. The new Sw-522 M1 strain obtained, which improved activity of α-1, 3 glucanase.