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Simulation of in-situ preheating of ni-based multi-layer and multi-pass coatings on H13 steel
Honggang Yin,Jinhua LI,Liwei Zhao,Fangping Yao 대한기계학회 2022 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.36 No.9
COMSOL was used to simulate the temperature field of the preheating and nonpreheating processes of the laser cladding multi-layer and multi-pass coating, and experimental verification was carried out. The results show that the temperature gradient value of the coating at the Z-axis is much larger than the value at the X and Y-axis, respectively. It indicates that the coating is sensitive to cracks at the Z-axis. After preheating, the quality of the coating is improved, and the results of the geometric morphology in experiments are basically consistent with the results of simulation. With increase in coating temperature, the cladding efficiency increased. The difference of temperature between the first and second layer was significantly reduced. The temperature gradient value at the Z-axis decreased. The coating grain structure presents as refined and well-distributed. The temperature gradient size in each layer decreased with the number of coatings increasing.
Ultrathin Biocompatible Electrospun Fiber Films for Self-Powered Human Motion Sensor
Gengrui Zhao,Shaobo Gong,Honggang Wang,Junfang Ren,Na Wang,Yawen Yang,Gui Gao,Shengsheng Chen,Linlin Li 한국정밀공학회 2021 International Journal of Precision Engineering and Vol.8 No.3
In recent years, triboelectric nanogenerator (TENG) has been proven to be an effective and simple solution for self-powered wearable sensing, and a wide variety of materials and methods have been applied to TENG based sensors. In this study, an ultrathin fiber film with nanoporous brain-like structure (BUF) was obtained by cold-pressing the electrospun biocompatible fiber mats, and a wearable TENG sensor based on the BUF films that could sensitively detect human motion was demonstrated. This simply designed self-powered sensor was composed of Kapton as the shell and ultrathin, biocompatible poly L-lactic acid and ethyl cellulose (EC) fiber films as the triboelectric layers, prepared by convenient electrospinning method and cold-pressing. Compared to as-spun fiber mats, cold-pressed fiber membranes not only acquire overall compact structure but also remained porous surface morphology, which improved the triboelectric outputs and operational stability of TENG. Three TENGs were fabricated to evaluate the effects of different triboelectric layers on triboelectric outputs, and the BUF-TENG had the maximum triboelectric outputs (19 V, 630 nA at 3.5 Hz) and longer life than as-spun fiber mats based TENG. The BUF-TENG had linear relationship between triboelectric outputs and frequency, and sensitivities of 32.4, 0.94 and 0.22 V Hz−1 in the range of 0.1–0.35, 0.35–2 and 2–3.5 Hz, respectively. Moreover, a self-powered sensor based on the BUF-TENG was proposed to sensitively detect human walking state and limbs motion. With convenient preparation process and biocompatible materials, the BUF-TENG sensor could be a potential self-powered wearable and portable sensor in future health care and monitoring field.
Liu, Yongfeng,Zan, Linsen,Zhao, Shuanping,Huang, Honggang,Li, Yong,Tang, Zhonglin,Yang, Shulin,Li, Kui Korean Society for Molecular and Cellular Biology 2010 Molecules and cells Vol.30 No.5
Ubiquinol-cytochrome c reductase complex chaperone (UQCC) involved in the development and maintenance of bone and cartilage is an important candidate gene for body measurement traits selection through marker-assisted selection (MAS). The expression of UQCC is upregulated in many human and animal models of height as well as other stature indexes. We have cloned the cDNA sequence coding UQCC gene in bovine. Genomic structural analysis indicated that bovine UQCC shares a high similarity with human UQCC. Furthermore, Real-Time PCR analysis showed that the expression of bovine UQCC is remarkably different in diverse tissues, including high level expression in the spleen, heart and windpipe, and relatively low expression in other tissues. We also analyzed allele frequencies in different cattle breeds and an association study on the selected SNPs. SNP DraI A2691T in intron 1 and SNP Bsh1236I A3150G in intron 8 are significantly associated with Body Length (BL), Rump Length (RL), Chest Depth (CD) and Pin Bone Width (PBW). For the A2691T SNP marker, there are significant effects on the RL (p = 0.0001), CD (p = 0.0059) and PBW (p < 0.0001) in 679 individuals; with A3150G SNP marker, there are significant effects on the BL (p = 0.0047) and CD (p = 0.0454). Regarding association analysis of combination of the two SNPs, there are significant effects on the BL (p = 0.0215), CD (p = 0.0282) and PBW (p = 0.0329) in the total population. The results suggest that the UQCC gene is a candidate gene of body measurement traits in bovine reproduction and breeding, and provide data for establishing an animal model using cattle to study big animal body type.
Yan Zou,Qiuye Wu,Qingjie Zhao,Honggang Hu,Lina Hu,Shichong Yu,Mingjuan Xu 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.12
To explore the more active antitumor compounds, two series of new xanthones, containing 1,4-disubstituted-1,2,3-triazole moiety were designed and synthesized. Eaton’s Reagent and “click reaction” were used in the synthesis. Most of the title compounds showed good inhibitory activity against the hepatoma carcinoma cell line (Bel-7402) and human cervical carcinoma cell line (HeLa) in vitro. Compounds 10a, 10e, 10f, 11r and 11t had potent activity with IC50 values, ranging from 2.2 ± 0.17 to 7.1 ± 0.27 μM, which was equivalent to Doxorubicin.
Yongfeng Liu,Linsen Zan,Shuanping Zhao,Honggang Huang,Yong Li,Zhonglin Tang,Shulin Yang,Kui Li 한국분자세포생물학회 2010 Molecules and cells Vol.30 No.5
Ubiquinol-cytochrome c reductase complex chaperone (UQCC) involved in the development and maintenance of bone and cartilage is an important candidate gene for body measurement traits selection through marker-assisted selection (MAS). The expression of UQCC is upregulated in many human and animal models of height as well as other stature indexes. We have cloned the cDNA sequence coding UQCC gene in bovine. Genomic structural analysis indicated that bovine UQCC shares a high similarity with human UQCC. Furthermore, Real-Time PCR analysis showed that the expression of bovine UQCC is remarkably different in diverse tissues, including high level expression in the spleen, heart and windpipe, and relatively low expression in other tissues. We also analyzed allele frequencies in different cattle breeds and an association study on the selected SNPs. SNP DraI A2691T in intron 1 and SNP Bsh1236I A3150G in intron 8 are significantly associated with Body Length (BL), Rump Length (RL), Chest Depth (CD) and Pin Bone Width (PBW). For the A2691T SNP marker, there are significant effects on the RL (p = 0.0001), CD (p = 0.0059) and PBW (p < 0.0001) in 679 individuals; with A3150G SNP marker, there are significant effects on the BL (p = 0.0047) and CD (p = 0.0454). Regarding association analysis of combination of the two SNPs, there are significant effects on the BL (p = 0.0215), CD (p = 0.0282) and PBW (p = 0.0329) in the total population. The results suggest that the UQCC gene is a candidate gene of body measurement traits in bovine reproduction and breeding, and provide data for establishing an animal model using cattle to study big animal body type.