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인공진피(Terudermis)를 사용한 심부피부 및 연부조직결손에 대한 치료
신준호,야나가(다나베) 히로코,다이 요시아키,기요카와 켄스케,이노우에 요지로,이정형,백봉수 大韓成形外科學會 1997 Archives of Plastic Surgery Vol.24 No.5
Various reconstructive procedures have been applied for the skin and soft tissue defect. However, the sacrifice of the donor site in flap surgery and skin grafting and involving problems of deformity or adhesion with underlying tissue in skin have facilitated the development of skin substitute. The history of artificial skin starred in 1980's with the invention of the "Stage I" membrane by Yannas, and Burke. Since then, it has been improved and applied to the clinical cases of extensive burn injury and full thickness skin defect the resection of the nevus. Recently, an artificial dermis(Terudermis), which is composed of fibrillar athelocollagens and heat-denaturated athelocollagens was developed by Terumo Co. Terudermis has the advantage of allowing early incorporation of cellular and vascular components into its collagen sponge due to dehydrothermal cross linking which is very weak. It is very suitable biological material especially in the reconstruction of the deep skin defects without dermis. From Jun 1996 to April 1997, we have grafted this artificial dermis on bony exposures after the trauma in 2 cases, and the deep skin and the soft tissue defects after the release of burn scar contracture in 1 case. Patients follow-up period ranged from 6 months to 10 months. A week after Terudermis grafting neovasculization took place and the granulation tissues appeared in 2-3 weeks. Then the split-thickness skin graft was applied secondarily resulting in the reproduction of enough volume of skin. For this matter, Terudermis is very useful for deep skin defects especially where primary local flap or free flap can not be used.
Risa Hara,Kiichi Hirota,Masami Sato,Hiroko Tanabe,Tomoko Yazawa,Toshie Habara,Kazuhiko Fukuda 대한마취통증의학회 2013 Korean Journal of Anesthesiology Vol.65 No.2
Background: Ambulatory surgery, including short-stay surgery, has become a common choice in clinical practice. For the success of ambulatory surgery, perioperative care with safe and effective anesthesia and postoperative analgesia, which can reduce the occurrence of postoperative nausea and vomiting (PONV), is essential. The effect of remifentanil on the occurrence and severity of PONV has not been thoroughly examined, particularly, in an ambulatory surgery setting. Here, we investigate whether remifentanil influences the occurrence and severity of PONV in a university hospital-based ambulatory unit. Methods: We retrospectively analyzed a total of 1,765 cases of patients who had undergone general anesthesia at our ambulatory surgery unit. Parameters, such as occurrence and severity of nausea, vomiting or retching, use of antiemetic drugs, amount of postoperative analgesic and patient satisfaction, were extracted from the records and analyzed between the groups that received and not received remifentanil. Results: Within 565 patients of the RF group, 39 patients (6.6%) experienced nausea, 7 patients (1.2%) experienced vomiting or retching, and 10 patients (1.8%) were given antiemetic; in addition, the maximum VAS value for nausea was 12.1 mm. In 1,200 patients of the non RF group, 102 patients (8.5%) experienced nausea, 19 patients (1.6%) experienced vomiting or retching, and 34 patients (2.8%) were given antiemetic, and the maximum VAS value was 13.2 mm. There were no statistically significant differences between the two groups. Conclusions: Our results indicate that remifentanil did not increase the occurrence of PONV in patients within the ambulatory surgery unit.
Xiao Ma,Satoshi Tsuda,Xin Yang,Ning Gu,Hiroko Tanabe,Rieko Oshima,Tetsuya Matsushita,Tatsuro Egawa,Ai-Jun Dong,Bei-Wei Zhu,Tatsuya Hayashi 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.3
Skeletal muscle is a major organ that is important for whole-body glucose metabolism. We found that when isolated rat epitrochlearis muscle was incubated with a Pu-erh tea hot-water extract (PTE) for 30 min, the rate of 3-O-methyl-D-glucose (3MG) transport increased in the absence of insulin. This activation was associated with an increase in Ser473 phosphorylation of Akt, a signaling intermediary leading to insulin-dependent glucose transport, but not Tyr458 phosphorylation of phosphoinositide 3-kinase p85, an upstream molecule of Akt. PTE-stimulated 3MG transport was also not accompanied by Thr172 phosphorylation of the catalytic α-subunit of 5′-AMP-activated protein kinase (AMPK). Gallic acid, a water-soluble ingredient in Pu-erh tea, stimulated Akt phosphorylation, but not AMPK phosphorylation. These results suggest that Pu-erh tea potentially promotes skeletal muscle glucose transport at least in part by activating Akt.
Kazuto Yamashita,Hisanari Ishii,Kiichi Hirota,Masami Sato,Hiroko Tanabe,Kazuhiko Fukuda,박문호,권도영,김용현 대한마취통증의학회 2012 Korean Journal of Anesthesiology Vol.62 No.5
Stress-induced cardiomyopathy, also referred to Takotsubo cardiomyopathy or apical ballooning syndrome presents in perioperative period. We demonstrated a case of Takotsubo cardiomyopathy recognized after general anesthesia for bladder hydrodistension therapy as ambulatory surgery, which we surmise was due to inadequate blockage of surgical stress and sympathetic discharge against noxious stimulus during ambulatory anesthesia.
유방증대술후 실리콘 노출과 감염을 일으킨 재생불량성 빈혈 환자의 치험례:1례 보고
조병채,기요카와 캔스케,백봉수,이노우에 요지로,다이 요시아키,야나가(다나베)히로코,신준호,이정형 大韓成形外科學會 1997 Archives of Plastic Surgery Vol.24 No.6
This 53 years old female patient ha had a history of aplastic anemia for 20 years. She had augmentation mammaplasty with silicone gel injection 16 years ago but 10 years later the injected material was partly removed due to induration and skin ulceration. Six years after partial removal of the foreign material, she developed infection again in both breasts and skin ulceration in the left breast, and surgery became inevitable. The laboratory data on admission(WBC : 2600/μℓ, Hb : 6.3/μℓ, platelet : 13.00μℓ) showed apparent pancytopenia and bone marrow aspiration revealed celluar hypoplasia(nucleated cell: 7,000/μℓ). Under interdepartment cooperation with the department of Hematology, general transfusion method(including HLA typing platelet transfusion) and cytokine therapy with G-CSF(granulocyte-colony stimulating factor) and erythropoietin were done to confront preoperative peripheral blood pancytopenia. As results of preoperative planned treatment, left simple mastectomy due to over-granulation and hematoma and right subcutaneous mastectomy could be performed without serious bleeding or other complication. Authors report this case to show effects of transfusion and therapy for the surgical treatment of an aplastic anemia patient.