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Trajectory-Based Design of Robust Stabilizing Controllers for Polytopic Uncertain Systems
Hiroki WADA,Hidetoshi OYA,Kojiro HAGINO,Yasumitsu EBINUMA 제어로봇시스템학회 2009 제어로봇시스템학회 국제학술대회 논문집 Vol.2009 No.8
This paper deals with a design problem of robust controllers for polytopic uncertain systems. The proposed design method is based on computation of the trajectory for the uncertain system and differs from the existing methods based on quadratic stabilization via Lyapunov criterion. In this paper, we show that sufficient conditions for asymptotical stability of the polytopic uncertain system and a LMI-based design algorithm of a robust stabilizing controller. Finally, the effectiveness of the proposed design scheme is shown through illustrative examples.
Hiroki Fukuya,Yoichiro Iboshi,Masafumi Wada,Yorinobu Sumida,Naohiko Harada,Makoto Nakamuta,Hiroyuki Fujii,Eikichi Ihara 대한소화기내시경학회 2023 Clinical Endoscopy Vol.56 No.6
We report a rare case of gastric cancer presenting with a gastrocolic fistula during ramucirumab and paclitaxel combination therapythat was successfully managed with colonic stenting. A 75-year-old man was admitted to our hospital with the chief complaint of mele-na. Esophagogastroduodenoscopy revealed a large ulcerated tumor in the lower stomach, judged by laparoscopy as unresectable (sT4b-N1M0). After four cycles of first-line chemotherapy with S-1 plus oxaliplatin, the patient showed disease progression, and second-linetherapy with ramucirumab and paclitaxel was started. At the end of the third cycle, the patient had gastric antral stenosis, which neces-sitated the placement of a gastroduodenal stent. When the patient complained of diarrhea 10 days later, esophagogastroduodenoscopyrevealed a fistula between the greater curvature of the stomach and the transverse colon. The fistula was covered by double colonicstenting, with a covered metal stent placed within an uncovered metal stent, after which leakage from the stomach to the colon stopped.
Effect of Seeding Layers on Preparation of PLZT Thin Films by Sol-Gel Method
Hirano, Tomio,Kawai, Hiroki,Suzuki, Hisao,Kaneko, Shoji,Wada, Tatsuya The Korean Ceramic Society 1999 The Korean journal of ceramics Vol.5 No.1
$(Pb_xLa_{1-x}) (Zr_yTi_{1-y})O_3$ (PLZT) thin films with electrooptic effect are promising for the optical application such as display or light shutter. However, it is difficult to use inexpensive and transparent glass substrates because the conventional process for preparation of PLZT requires temperatures above $600^{\circ}C$. In order to deposit a perovskite PLZT thin films at low processing temperatures through alkoxide route, we have offered several seeding processes which reduce the activation energy for crystallization. In this study, we optimized the stacking structure of multilayered PLZT for obtaining single phase perovskite at lower temperatures. As a result, ferroelectric PLZT thin films with different compositions were successfully prepared at a temperature as low at $500^{\circ}C$.
Nakamura, Akihiko,Watanabe, Hiroki,Ishida, Takuya,Uchihashi, Takayuki,Wada, Masahisa,Ando, Toshio,Igarashi, Kiyohiko,Samejima, Masahiro American Chemical Society 2014 JOURNAL OF THE AMERICAN CHEMICAL SOCIETY - Vol.136 No.12
<P>Analysis of heterogeneous catalysis at an interface is difficult because of the variety of reaction sites and the difficulty of observing the reaction. Enzymatic hydrolysis of cellulose by cellulases is a typical heterogeneous reaction at a solid/liquid interface, and a key parameter of such reactions on polymeric substrates is the processivity, i.e., the number of catalytic cycles that can occur without detachment of the enzyme from the substrate. In this study, we evaluated the reactions of three closely related glycoside hydrolase family 7 cellobiohydrolases from filamentous fungi at the molecular level by means of high-speed atomic force microscopy to investigate the structure–function relationship of the cellobiohydrolases on crystalline cellulose. We found that high moving velocity of enzyme molecules on the surface is associated with a high dissociation rate constant from the substrate, which means weak interaction between enzyme and substrate. Moreover, higher values of processivity were associated with more loop regions covering the subsite cleft, which may imply higher binding affinity. Loop regions covering the subsites result in stronger interaction, which decreases the velocity but increases the processivity. These results indicate that there is a trade-off between processivity and hydrolytic velocity among processive cellulases.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/jacsat/2014/jacsat.2014.136.issue-12/ja4119994/production/images/medium/ja-2013-119994_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/ja4119994'>ACS Electronic Supporting Info</A></P>