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OVERVIEW OF RECENT EFFORTS THROUGH ROSA/LSTF EXPERIMENTS
HIDEO NAKAMURA,TADASHI WATANABE,TAKESHI TAKEDA,YU MARUYAMA,MITSUHIRO SUZUKI 한국원자력학회 2009 Nuclear Engineering and Technology Vol.41 No.6
JAEA started the LSTF experiments in 1985 for the fourth stage of the ROSA Program (ROSA-IV) for the LWR thermal-hydraulic safety research to identify and investigate the thermal-hydraulic phenomena and to confirm the effectiveness of ECCS during small-break LOCAs and operational transients. The LSTF experiments are underway for the ROSA-V Program and the OECD/NEA ROSA Project that intends to resolve issues in thermal-hydraulic analyses relevant to LWR safety. Six types of the LSTF experiments have been done for both the system integral and separate-effect experiments among international members from 14 countries. Results of four experiments for the ROSA Project are briefly presented with analysis by a best-estimate (BE) code and a computational fluid dynamics (CFD) code to illustrate the capability of the LSTF and codes to simulate the thermal-hydraulic phenomena that may appear during SBLOCAs and transients. The thermal-hydraulic phenomena dealt with are coolant mixing and temperature stratification, water hammer up to high system pressure, natural circulation under high core power condition, and non-condensable gas effect during asymmetric SG depressurization as an AM action.
OVERVIEW OF RECENT EFFORTS THROUGH ROSA/LSTF EXPERIMENTS
Nakamura, Hideo,Watanabe, Tadashi,Takeda, Takeshi,Maruyama, Yu,Suzuki, Mitsuhiro Korean Nuclear Society 2009 Nuclear Engineering and Technology Vol.41 No.6
JAEA started the LSTF experiments in 1985 for the fourth stage of the ROSA Program (ROSA-IV) for the LWR thermal-hydraulic safety research to identify and investigate the thermal-hydraulic phenomena and to confirm the effectiveness of ECCS during small-break LOCAs and operational transients. The LSTF experiments are underway for the ROSA-V Program and the OECD/NEA ROSA Project that intends to resolve issues in thermal-hydraulic analyses relevant to LWR safety. Six types of the LSTF experiments have been done for both the system integral and separate-effect experiments among international members from 14 countries. Results of four experiments for the ROSA Project are briefly presented with analysis by a best-estimate (BE) code and a computational fluid dynamics (CFD) code to illustrate the capability of the LSTF and codes to simulate the thermal-hydraulic phenomena that may appear during SBLOCAs and transients. The thermal-hydraulic phenomena dealt with are coolant mixing and temperature stratification, water hammer up to high system pressure, natural circulation under high core power condition, and non-condensable gas effect during asymmetric SG depressurization as an AM action.
Hideo Nakai,Taiju Hyuga,Shina Kawai,Taro Kubo,Shigeru Nakamura 대한비뇨의학회 2017 Investigative and Clinical Urology Vol.58 No.-
Vesicoureteral reflux (VUR) is one of the most common diseases in pediatric urology and classified into primary and secondary VUR. Although posterior urethral valve (PUV) is well known as a cause of the secondary VUR, it is controversial that minor urethral deformity recognized in voiding cystourethrography represents mild end of PUV spectrum and contributes to the secondary VUR. We have been studying for these ten years congenital urethral obstructive lesions with special attention to its urethrographic and endoscopic morphology as well as therapeutic response with transurethral incision. Our conclusion to date is that congenital obstructive lesion in the postero-membranous urethra is exclusively PUV (types 1 and 3) and that severity of obstruction depends on broad spectrum of morphological features recognized in PUV. Endoscopic diagnostic criteria for PUV are being consolidated.
( Shiro Nakamura ),( Hirotsugu Imaeda ),( Hiroki Nishikawa ),( Masaki Iimuro ),( Minoru Matsuura ),( Hideo Oka ),( Junsuke Oku ),( Takako Miyazaki ),( Hirohito Honda ),( Kenji Watanabe ),( Hiroshi Nak 대한장연구학회 2018 Intestinal Research Vol.16 No.4
Background/Aims: Noninvasive objective monitoring is advantageous for optimizing treatment strategies in patients inflammatory bowel disease (IBD). Fecal calprotectin (FCP) is superior to traditional biomarkers in terms of assessing the activity in patients with IBD. However, there are the differences among several FCP assays in the dynamics of FCP. In this prospective multicenter trial, we investigated the usefulness of FCP measurements in adult Japanese patients with IBD by reliable enzyme immunoassay using a monoclonal antibody. Methods: We assessed the relationship between FCP levels and disease or endoscopic activity in patients with ulcerative colitis (UC, n=64) or Crohn’s disease (CD, n=46) compared with healthy controls (HCs, n=64). Results: FCP levels in UC patients strongly correlated with the Disease Activity Index (r<sub>s</sub>=0.676, P<0.0001) and Mayo endoscopic subscore (MES; r<sub>s</sub>=0.677, P<0.0001). FCP levels were significantly higher even in patients with inactive UC or CD compared with HCs (P=0.0068, P<0.0001). The optimal cutoff value between MES 1 and 2 exhibited higher sensitivity (94.1%). FCP levels were significantly higher in active UC patients than in inactive patients (P<0.001), except those with proctitis. The Crohn’s Disease Activity Index tended to correlate with the FCP level (rs=0.283, P=0.0565). Conclusions: Our testing method using a monoclonal antibody for FCP was well-validated and differentiated IBD patients from HCs. FCP may be a useful biomarker for objective assessment of disease activity in adult Japanese IBD patients, especially those with UC. (Intest Res 2018;16:554-562)
Multichannel Temporal Data Classification of Motor Imagination Using fNIRS
Sei Takahashi,Hideo Nakamura,Hitoshi Tsunashima 제어로봇시스템학회 2010 제어로봇시스템학회 국제학술대회 논문집 Vol.2010 No.10
We describe classification of functional near-infrared spectroscopy (fNIRS) data acquired during finger tapping imagery tasks performed by a human subject, using an artificial neural network designed for image sequence recognition. Our goal is to develop a brain-computer interface that can handle various intentions of users. We used an fNIRS system to collect neural information from brain activity. For discrimination of the fNIRS data, we used our previously proposed neural network model called the Neocognitron-type Image Sequence Recognition Model (Neo-ISRM), which is suitable for analyzing multichannel temporal patterns. Finger tapping imagery of both left and right hands was used as the mental tasks to be discriminated with Neo-ISRM. The model gave good discrimination results for each category of tasks from data for the motor area, the prefrontal area, and the frontal lobe. In all experiments, we confirmed that the discrimination results for the frontal lobe had fewer discrimination errors compared with the results for both the motor and prefrontal areas.