http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Signal Transduction Pathways : Targets for Green and Black Tea Polyphenols
Bode, Ann M.,Dong, Zigang 한국생화학분자생물학회 2003 BMB Reports Vol.36 No.1
Tea is one of the most popular beverages consumed in the world and has been demonstrated to have anti-cancer activity in animal models. Research findings suggest that the polyphenolic compounds, (-)-epigallocatechin-3-gallate found primarily in green tea, and theaflavin-3, 3'-digallate, a major component of black tea, are the two most effective anti-cancer factors found in tea. Several mechanisms to explain the chemopreventive effects of tea have been presented but others and we suggest that tea components target specific cell-signaling pathways responsible for regulating cellular proliferation or apoptosis. These pathways include signal transduction pathways leading to activator protein-1 (AP-1) and/or nuclear factor kappa B (NF-κB). AP-1 and NF-κB are transcription factors that are known to be extremely important in tumor promoter-induced cell transformation and tumor promotion, and both are influenced differentially by the MAP kinase pathways. The purpose of this brief review is to present recent research data from other and our laboratory focusing on the tea-induced cellular signal transduction events associated with the MAP kinase, AP-a, and NF-κB pathways.
Signal Transduction Pathways: Targets for Green and Black Tea Polyphenols
Bode, Ann M.,Dong, Zigang Korean Society for Biochemistry and Molecular Biol 2003 Journal of biochemistry and molecular biology Vol.36 No.1
Tea is one of the most popular beverages consumed in the world and has been demonstrated to have anti-cancer activity in animal models. Research findings suggest that the polyphenolic compounds, (-)-epigallocatechin-3-gallate, found primarily in green tea, and theaflavin-3,3'-digallate, a major component of black tea, are the two most effective anti-cancer factors found in tea. Several mechanisms to explain the chemopreventive effects of tea have been presented but others and we suggest that tea components target specific cell-signaling pathways responsible for regulating cellular proliferation or apoptosis. These pathways include signal transduction pathways leading to activator protein-1 (AP-1) and/or nuclear factor kappa B(NF-${\kappa}B$ ). AP-1 and NF-${\kappa}B$ are transcription factors that are known to be extremely important in tumor promoter-induced cell transformation and tumor promotion, and both are influenced differentially by the MAP kinase pathways. The purpose of this brief review is to present recent research data from other and our laboratory focusing on the tea-induced cellular signal transduction events associated with the MAP kinase, AP-1, and NF-${\kappa}B$ pathways.
SURINA, FARUNG,BODE, MICHAEL F.,DARNLEY, MATTHEW J. The Korean Astronomical Society 2015 天文學論叢 Vol.30 No.2
Classical novae (CNe) are interacting binary systems whose outbursts are powered by a thermonuclear runaway in accreted material onto the surface of a white dwarf (WD). The secondary star in such systems fills its Roche lobe and material is transferred onto the WD primary star via an accretion disk. Recurrent novae (RNe) show many similarities to CNe, but have had more than one recorded outburst. RNe play an important role as one of the suspected progenitor systems of Type Ia supernovae, which are used as primary distance indicators in cosmology. Thus, it is important to investigate the nature of their central binary systems to determine the relation between the parameters of the central system and the outburst type, and finally ascertain the population of novae that might be available to give rise to the progenitors of Type Ia SNe. A low outburst amplitude is adopted as a criterion that may help distinguish RNe from CNe and was therefore used to select targets for observations from ground-based observatories including the Liverpool Telescope and the Southern African Large Telescope as well as the full-sky space-based archive of the Solar Mass Ejection Imager (SMEI). We found that at least four objects currently classified as CNe are possibly RNe candidates based on their quiescent spectra. We also searched the SMEI archive for additional outbursts of bright CNe that might otherwise have been missed but did not find a conclusive example.