http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Han Wool Lee,Hyoung Jean Beak,Eun-Jung Yoon,김주영 대한운동학회 2021 아시아 운동학 학술지 Vol.23 No.2
[OBJECTIVES] This study aims to investigate the effects of instrument-assisted soft tissue mobilization (IASTM) on ankle range of motion (ROM) and balance in older women. [METHODS] The 20 older women with a history of falls participated in the study, and the study subjects were randomly divided into the IASTM group (n=10) and control group (n=10). [RESULTS] There were no significant interactions between group and time for ankle ROM and functional reach after 8 weeks of IASTM on older women (P>0.05). Meanwhile, there were significant interactions between group and time for one-leg standing and star excursion balance (P<0.05), and in particular, the IASTM group had greater improvements compared to the control group. [CONCLUSION] In conclusion, the regular application of IASTM has been shown to improve the balance of older women with a history of falls.
Lee Seon Yeong,Jang Han Wool,Lee Hae Ri,Joh Han-Ik 한국탄소학회 2021 Carbon Letters Vol.31 No.6
Metal–organic frameworks (MOFs) are widely used as supports for single-atom catalysts (SACs) owing to their high specifc surface area, porosity, and ordered metal–ligand structure. Their activity can be increased by increasing the number of electrochemically accessible active sites via the formation of atomically dispersed metal catalysts (M–Nx) that coordinate with nitrogen atoms on the MOF. Herein, we introduce the relationship between the size of the MOF as a starting material and the catalytic activity for the oxygen reduction reaction in alkaline media. The morphology and features of the MOFs are critically dependent on their size. Remarkably, cage-like MOFs below 33 nm are converted into collapsed structures and are connected between each MOF, even carbon fber- or tube-like features, after carbonization. SACs derived from medium-sized MOFs exhibit excellent activity and are comparable to commercial Pt/C catalysts owing to their porous structure. Therefore, we believed that controlling the size of MOFs containing active atoms is an efective method of modulating the morphological properties of the support and even the number of active sites that are closely related to the activity.
Han‑Wool Jang,Seon Yeong Lee,Jong Yoon Lee,Han‑Ik Joh 한국탄소학회 2023 Carbon Letters Vol.33 No.1
Ammonia is considered a promising hydrogen carrier due to its high hydrogen density and liquefaction temperature. Considering that the energy efficiency generally decreases as chemical conversion is repeated, it is more efficient to directly use ammonia as a fuel for fuel cells. However, catalysts in direct ammonia fuel cells have the critical issues of sluggish ammonia oxidation reaction (AOR) rate and poisoning of reaction intermediates. In particular, the use of precious metal as cathodic catalysts has been limited due to ammonia crossover and poisoning. In this study, we introduce Fe-based single-atom catalysts with selective activity for the oxygen reduction reaction (ORR) even in the presence of ammonia. As the Fe content increased, the single-atom structure of the catalysts changed into Fe nanoparticles or carbides. Among our Fe–N–C catalysts, FeNC-50 with a Fe loading amount of 0.34 wt% showed the highest ORR performance regardless of the ammonia concentration. In particular, the difference in activity between the catalysts increased as the concentration increased. The FeNC-50 catalyst showed remarkable stability after 1000 cycles. Therefore, we believe that single-atom dispersion is an important factor in the development of stable non-precious catalysts with high activity and inactivity for the ORR and AOR, respectively.
Lee, Han-Wool,Lee, Chang-Seok The Korean Society for Integrative Biology 2006 Integrative biosciences Vol.10 No.1
Tree of heaven (Ailanthus altissima Swingle) as an invasive alien plant, appeared usually in the disturbed locations such as road-side, incised slope, and trampling path-side. They appeared abundantly in the trampling pathside but they did not appear or were rare in the interior of forest. Density and importance value of tree of heaven were proportionate to the relative light intensity measured according to distance from the trampling path toward forest interior and closely related to the breadth of trampling path as well. They were associated with annual, other exotic species or ruderal plants well. Distributional pattern of mature trees of them in the study area and its surrounding environments implied that they were introduced intentionally. Size class distribution of them showed that they are in expansion and artificial interferences such as, installing physical training space and developing hiking course functioned as trigger factors in their invasion and expansion. The results support the facts known generally in relation to invasion and expansion of the invasive alien plants. In this viewpoint, we suggest a management plan that applies ecological restoration principles to address ecosystems infected with tree of heaven by restoring the integral feature of the degraded nature and conserving the remained nature more thoroughly.
Choung, Han-Wool,Lee, Dong-Seol,Lee, Hye-Kyung,Shon, Won-Jun,Park, Joo-Cheol Mary Ann Liebert 2016 Tissue engineering. Part A Vol.22 No.1
<P>Epithelial-mesenchymal interaction occurs during development of various tissues, including teeth and bone. Recently, a preameloblast-conditioned medium (PA-CM) from mouse apical bud cells (ABCs), a type of dental epithelial cell, was found to induce odontogenic differentiation of dental pulp stem cells and promote dentin formation. The aims of the present study were to investigate the effects of PA-CM on human bone marrow mesenchymal stem cells (hBMSCs) in vitro, and to investigate the bone regenerative capacity in vivo through epithelial-mesenchymal interactions of developmental osteogenesis. Coculturing with ABCs and PA-CM treatment upregulated osteoblast differentiation markers of hBMSCs compared to cells cultured alone. PA-CM accelerated mineralized nodule formation and also increased bone sialoprotein promoter activity in hBMSCs. PA-CM facilitated the migration of hBMSCs, but did not significantly influence proliferation. PA-CM promoted bone formation of hBMSCs in vivo. Radiographic and histologic findings showed that PA-CM induced the bony regeneration at calvarial defects in rat. Taken together, these data show that PA-CM enhances the migration and osteogenic differentiation of hBMSCs in vitro and induces bone formation in vivo.</P>
이한울(Lee, Han-Wool),권영상(Kwon, Young) 한국도시설계학회 2016 도시설계 : 한국도시설계학회지 Vol.17 No.2
본 연구는 최근 주변의 주거지역이 상업적 용도로 변화하면서 확장된 홍대 문화소비공간을 대상으로 그 특성을 분석한 연구이다. 홍대, 삼청동, 이태원 등의 문화소비공간은 독특한 장소경험이라는 측면에서 많은 사람들이 방문하고 있는 상업지역이며, 주변의 단독/단세대 주거지역으로 확장되고 있다. 기존 문화소비공간이 상업적으로 발달하면서 임대료 상승 등의 요인으로 기존의 소규모 시설들이 경계부 단독/다세대 주거지역에 새로 입지하여 상업공간을 형성하고 있다. 본 연구에서는 2009년부터 2015년까지의 용도변화를 관찰하여, 홍대 문화소비공간의 확장과정을 분석했다. 또한 상업용도로의 변화와 가로구조, 필지, 건축물의 물리적 특성의 관계의 분석을 통해서 상업용도의 확장과정에서 주거지역의 물리적 환경이 상관성을 갖는지를 분석하였다. 그 결과 보행흐름과의 접근성과 건축물의 규모적 특성은 상업용도의 변화 및 확장과정과 관련이 있는 것으로 나타났다. This study analyzes the pattern of commercial use expansion and the changes of individual buildings in a residential area at the periphery of the cultural quarter near Hongik University. It aims to apprehend the mechanism of changes in building use at the periphery of the cultural quarter. The cultural quarter has expanded through the migration of native alternative stores resulting from increases in commercial rents. In this study, this process is examined as an expansion of the cultural quarter. Building use changes between 2009 and 2015 are observed and analyzed. The results show that most of the blocks with many frequent changes in building use are located near the street where the main pedestrian flow is observed. The accessibility of the main pedestrian flow and pedestrian-friendly facilities plays an important role in the expansion. Not only the urban street system, but also building size influence commercialization.
Kim, Han Wool,Lee, Hyun-Seob,Kang, Jun Mo,Bae, Sang-Hun,Kim, Chul,Lee, Sang-Hun,Schwarz, Johannes,Kim, Gi Jin,Kim, Jin-Su,Cha, Dong Hyun,Kim, Joopyung,Chang, Sung Woon,Lee, Tae Hee,Moon, Jisook Cognizant Communication Corp. 2018 CELL TRANSPLANTATION Vol. No.
<P>Parkinson’s disease (PD) is the second most common age-related neurodegenerative disease in the elderly and the patients suffer from uncontrolled movement disorders due to loss of dopaminergic (DA) neurons on substantia nigra pars compacta (SNpc). We previously reported that transplantation of human fetal midbrain-derived neural precursor cells restored the functional deficits of a 6-hydroxy dopamine (6-OHDA)-treated rodent model of PD but its low viability and ethical issues still remain to be solved. Albeit immune privilege and neural differentiation potentials suggest mesenchymal stem cells (MSCs) from various tissues including human placenta MSCs (hpMSCs) for an alternative source, our understanding of their therapeutic mechanisms is still limited. To expand our knowledge on the MSC-mediated PD treatment, we here investigated the therapeutic mechanism of hpMSCs and hpMSC-derived neural phenotype cells (hpNPCs) using a PD rat model. Whereas both hpMSCs and hpNPCs protected DA neurons in the SNpc at comparable levels, the hpNPC transplantation into 6-OHDA treated rats exhibited longer lasting recovery in motor deficits than either the saline or the hpMSC treated rats. The injected hpNPCs induced delta-like ligand (DLL)1 and neurotrophic factors, and influenced environments prone to neuroprotection. Compared with hpMSCs, co-cultured hpNPCs more efficiently protected primary neural precursor cells from midbrain against 6-OHDA as well as induced their differentiation into DA neurons. Further experiments with conditioned media from hpNPCs revealed that the secreted factors from hpNPCs modulated immune responses and neural protection. Taken together, both DLL1-mediated contact signals and paracrine factors play critical roles in hpNPC-mediated improvement. First showing here that hpMSCs and their neural derivative hpNPCs were able to restore the PD-associated deficits via dual mechanisms, neuroprotection and immunosuppression, this study expanded our knowledge of therapeutic mechanisms in PD and other age-related diseases.</P>