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      • 주상복합 건축물의 사이공간 활용방안에 관한 계획안 연구

        함태영(Ham. Tai-Young),박현수(Park. Hyeon-Soo) 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1

        This study proposes a mixed~use building plan which aims to overcome the problem of barrier between upper and lower level of the complex building. The proposed building plan suggests an inter~space, having the feasibility of user contact with people's movement as well as open sight, and pleasant space with community rest zone. It is also planned to provide cultural public space to serve community neighborhoods, hereby, connecting isolated urban spots. Related design methods and issues were searched to find a relevant data for this study.

      • SCISCIESCOPUS

        Label-Free Quantitative Immunoassay of Fibrinogen in Alzheimer Disease Patient Plasma Using Fiber Optical Surface Plasmon Resonance

        Kim, Jisoo,Kim, SeJin,Nguyen, Tan Tai,Lee, Renee,Li, Tiehua,Yun, Changhyun,Ham, Youngeun,An, Seong Soo A.,Ju, Heongkyu Springer-Verlag 2016 Journal of electronic materials Vol.45 No.5

        <P>We present a real-time quantitative immunoassay to detect fibrinogen in the blood plasma of Alzheimer's disease patients using multimode fiber optical sensors in which surface plasmon resonance (SPR) was employed. Nanometer-thick bimetals including silver and aluminum were coated onto the core surface of the clad-free part (5 cm long) of the fiber for SPR excitation at the He-Ne laser wavelength of 632.8 nm. The histidine-tagged peptide was then coated on the metal surface to immobilize the fibrinogen antibody for the selective capture of fibrinogen among the proteins in the patient blood plasma. The SPR fiber optical sensor enabled quantitative detection of concentrations of fibrinogen from the different human patient blood at a detection limit of 20 ng/ml. We also observed a correlation in the fibrinogen concentration measurement between enzyme-linked immunosorbent assay and our SPR fiber-based sensors. This suggests that the presented SPR fiber-based sensors that do not rely on the use of labels such as fluorophores can be used for a real-time quantitative assay of a specific protein such as fibrinogen in a human blood that is known to contain many other kinds of proteins together.</P>

      • KCI등재후보

        두개 이열증을 동반한 Robinow 증후군 (Fetal Face Syndrome) 1례

        김기은(Ki Eun Kim),함태영(Tai Young Ham),강두철(Doo Choel Kang),고창준(Chang Jun Coe),이준수(Joon Soo Lee) 대한소아신경학회 2003 대한소아신경학회지 Vol.11 No.2

        저자들은 경련을 주소로 내원한 환아에서 저신장을 보이며 전형적인 태아 얼굴 모양과 전완단증, 미소음경의 임상소견을 특징으로 하고 두개 이열증을 동반한 Robinow 증후군 1례를 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Robinow syndrome is a rare inherited disorder initially reported by Robinow et al. in 1969 as a new dwarfing syndrome. It is characterized by the presence of fetal face, forearm shortening, genital hypoplasia, and hemivertebrae. The autosomal recessive form of Robinow syndrome shows a more severe clinical phenotype which is expressed by the mutation of homozygous ROR2(Receptor tyrosine kinase like Orphans) gene, mapped to the chromosome 9q22, a region that overlaps the locus for autosomal dominant inherited brachydactyly type B(BDB). ROR2 encodes the receptor tyrosine kinase, which is important for the development of mesomelic long bones. We experienced a boy diagnosed as a Robinow syndrome with fetal face(frontal bossing, hypertelorism, small up-turned nose, triangular mouth with down turned angles, micrognathia), large anterior fontanelle, cranium bifidum, mesomelic shortening, cryptorchidism. We present this case with a brief review of related literature.

      • SCOPUSKCI등재

        도축돈에서 Pasteurella multocida의 분리, 분리주에 대한 미생물학적, 혈청학적성상 및 항생물질의 감수성조사와 돈폐에 대한 병리학적 관찰에 관하여

        이학철,함태수,정유열,조성룡,이재현,Lee Hak-Cheol,Ham Tai-Soo,Chung Yoo-Yeol,Cho Seong-Lyong,Lee Jag-Hyeon 한국임상수의학회 1989 한국임상수의학회지 Vol.6 No.2

        In recent years much attention has been paid to swine respiratory infection caused by Pasteurella(P) multocida with rapid expansion of pork Industry in Korea. The present study was performed to observe the etiologic situation of P. multocida infection by bacteriological, serological(serotyping) and pathological examinations with the lungs respectively. In addition antibiotic susceptibility test was carried out against the isolated strains of P. multocida. The results obtained are as follows : 1. Eighteen strains(12.8%) wert isolated from the 140 cases of swine lungs examined, and biological and biochemical characteristics of the isolates were the sam as those in the references of other workers, whereas some differences were observed in sugar fermentation and enzyme activity according to the strain of isolates. 2. Capsular serotyping performed on 18 P. multocida revealed that 13 strains(72.2%) were A type and 5 strains(27.8%) were D type, respectively. 3. When serotyping was performed against somatic antigen on 18 strains capsular types of which were identified as described above 9(50%), 3(16.7%) and 4(22.2%) strains belong to 1:A, 3:A and 2:D, respectively, but untypable 2 strains(11.1%) were observed. 4. Antibiotic susceptibility test by employing disc method for 24 kinds of drugs revealed that 15 kinds of antibiotics were sensitive to 18 strains of P. multocida isolated such as ampicillin(l00%), penicillin(100%), cloxacillin(56%), piperacillin(70%), cefotaxime(30%), minocycline(60%), chloramphenicol(95%), erythromycin(39%), kanamycin(17%), gentamicin(70%), amikasin(30%), colistin(78%) and nalidixic acid(5%), respectively, but resistant to 9 kinds of antibiotics such as sulpenicillin, cefazolin, cephalothin, cefametazol, cefoperazone, kitasamycin, oleandomycin. lincomycin and bacitracin. 5. Pathological features of 60 cases of swine lungs indicated that pneumonic .lesions were observed in 38 cases(63.3%) examined by macroscopic finding, in which lesions of 8 cases(13.4%) would correspond to those of mycoplasmal infection, and 30 cases(50%) were similar to viral infection by histopathological finding, whereas 22 cases(36.7%) were considered to be normal by ecropsy or histopathological finding.

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