Development of Train Regenerative Braking Ground Absorbing Device Based on Super Capacitor Energy Storage

LI Kunpeng,LIU Wei,LI Qunzhan,ZHAO Yunyun,HE Zhixin,SHI Haiou,JIN Shoujie,CHEN Guangzan 전력전자학회 2019 ICPE(ISPE)논문집 Vol.2019 No.5

The rational use of regenerative braking energy for urban rail transit trains directly affects the voltage safety of the traction power supply system and the electric braking function of the train. It is also of great significance for the implementation of train traction energy saving. This paper proposes a scheme of train regenerative braking ground absorbing device based on super-capacitor energy storage. It adopts multiple modular Buck/Boost DC conversion topology to realize bidirectional control of electric energy and stabilize the secondary utilization of traction network voltage and regenerative electric energy. According to the scheme of this paper, the energy storage device was developed and verified in the engineering of the Guangzhou Line 6 main line traction substation. The test indicators have met the design expectations.

Solution‑Processed Individual Multiple‑Junction Structure Self‑Assembled with ZnO Nanowires for UV/Blue Detection

Yan Li,Naisen Yu,Haiou Li,Dedi Liu,Yunfeng Wu 대한금속·재료학회 2020 ELECTRONIC MATERIALS LETTERS Vol.16 No.6

In this paper, a novel individual multiple-junction network structure is fabricated using low temperature aqueous method. In comparison with the same growth method without NaF adding, the Fluorine doped ZnO photodetector presents multiplejunctionnetwork structure and ultraviolet (UV)/Blue dual band photoresponse performances. The results indicate the method can simultaneously promote self-assembled growth and improve the photoresponse properties. Moreover, it will provide a simple and low cost way to assemble multiple nanowires for photoresponse applications.

A facile approach to preparing palladium nanoparticles-embedded polyvinylpyrrolidone (PVP) heterogeneous hybrid nanofibers mats by electrospinning

Jie Bai,Liping Guo,Haiou Liang,Tong Xu,Chunping Li,Qingrun Meng,Huan Liu,Yarong Huang 한국화학공학회 2013 Korean Journal of Chemical Engineering Vol.30 No.12

Well-dispersed palladium nanoparticles (Pd NPs) were prepared under the condition that trisodium citrate was the reduction agent and polyvinylpyrrolidone (PVP) was the stabilizing agent via sol-gel process. By making good use of the advanced electrospinning technology we obtained Pd NPs/PVP composite nanofibers films. Optical properties were examined by UV-visible absorbance spectra (UV-vis) and Fourier transform infrared spectroscopy (FTIR). The morphology and distribution of Pd NPs in/on PVP matrix were characterized by scanning electron microscope (SEM)and transmission electron microscope (TEM). The results showed that Pd NPs presented as spherical spots and distributed in/on PVP nanofibers uniformly; their diameter was 4-10 nm and decreased with the increase of PVP. The as-prepared Pd NPs/PVP hybrid mats possess catalytic activity, stability and reusability, as verified by performance in Heck reaction.

Olaparib induced senescence under P16 or P53 dependent manner in ovarian cancer

Zehua Wang,Jianwen Gao,Jiabing Zhou,Haiou Liu,Congjian Xu 대한부인종양학회 2019 Journal of Gynecologic Oncology Vol.30 No.2

Objective: Poly (ADP-ribose) polymerase (PARP) is an important molecule in the early stress response of DNA damage, which is involved in DNA damage repair and cellular senescence. Olaparib, as PARP inhibitor, has an anti-tumor effect on high grade serous ovarian cancer, but its effects on cellular senescence have not been reported. This study intends to explore the role of olaparib in the regulation of senescence in ovarian cancer cells. Methods: The effects of olaparib on the senescence of ovarian cancer cells were detected by using the senescence-associated β-galactosidase (SA-β-Gal) and senescence-associated heterochromatin aggregation (SAHF). Quantitative real-time polymerase chain reaction was used to analyze the senescence-associated secretory phenotype (SASP). Cell cycle and apoptosis were detected by flow cytometry. The effect of olaparib on tumor growth was analyzed in a nude mouse xenograft transplantation model. Results: Long-term (6 days) treatment with olaparib (5 μM) significantly inhibited the growth of ovarian cancer cells, leading to arrest the cell cycle at G0/G1 phase, significant increase the number of positive SA-β-Gal stained cells and positive SAHF cells. The expression of P16 and retinoblastoma protein (p-RB) were significantly enhanced in SKOV3 cells under olaparib treated, meanwhile, the expression of P53 and p-RB were upregulated in A2780 cells. In OVCAR-3 cells, the expression of P53 was downregulated and p-RB was upregulated. Mice with SKOV3 xenograft transplantation was given olaparib (10 mg/kg/day) via abdominal cavity administration, the tumor volume was reduced (p<0.01). Conclusion: Continuous low dosage administration of olaparib induced senescence under P16 or P53 dependent manner in ovarian cancer.

Novel Organic/Inorganic Hybrid Star Polymer Surface-Crosslinked with Polyhedral Oligomeric Silsesquioxane

Jingyan Zhang,Dong Si,Shifeng Wang,Hao Liu,Xiaoming Chen,Haiou Zhou,Mingdi Yang,Guoying Zhang 한국고분자학회 2020 Macromolecular Research Vol.28 No.2

Novel organic/inorganic hybrid star polymer was prepared dually crosslinked within inner-core via divinylbenzene (DVB) and outer-surface via octafunctional polyhedral oligomeric silsesquioxane (POSS). Core cross-linked star polymers bearing dialkynyl-terminated polystyrene arms, (dialkynyl-PS)n-CCL, were synthesized at first by the atom transfer radical polymerization (ATRP) of DVB using α,α-dialkynyl-terminated PS macroinitiator, followed by the subsequent fractionation. Under high dilution conditions, (dialkynyl-PS)n-CCL was subjected to surface cross-linking with octa(3- azidopropyl) polyhedral oligomeric silsesquioxane, POSS-(N3)8, via click reaction, affording POSS-functionalized hybrid polymer doubly cross-linked within core and surface regions, SCL-(PS)n-CCL. FT-IR, 1H NMR, GPC, and elemental analysis results revealed that on average, the obtained hybrid polymer possesses a cross-linked PDVB inner core, ~14 linear PS arms (the MW per arm of 5.1 kDa), and ~4-5 POSS moieties at outer surface. Differential scanning calorimetry (DSC) thermograms and thermogravimetric analysis (TGA) revealed that after surface cross-linking the thermal stability of SCL-(PS)n-CCL is considerably improved. This work provides a proof-of-concept example for the preparation of dually cross-linked hybrid star polymer, which represents a novel category of organic/inorganic composite materials with unique chain architectures.

The visible and ultraviolet organic light-emitting diodes with germanium dioxide as facile solution-processed anode buffer layer

Kai Xu,Zhenchang Tang,Yan Zhang,Wanshu Li,Haiou Li,Lihui Wang,Li-Ming Liu,Hong-Hang Wang,Feng Chi,Xiaowen Zhang 한국물리학회 2019 Current Applied Physics Vol.19 No.10

Germanium dioxide (GeO2) aqueous solutions are facilely prepared and the corresponding anode buffer layers (ABLs) with solution process are demonstrated. Atomic force microscopy, X-ray photoelectron spectroscopy and ultraviolet photoelectron spectroscopy measurements show that solution-processed GeO2 behaves superior film morphology and enhanced work function. Using GeO2 as ABL of organic light-emitting diodes (OLEDs), the visible device with tris(8-hydroxy-quinolinato)aluminium as emitter gives maximum luminous efficiency of 6.5 cd/A and power efficiency of 3.5 lm/W, the ultraviolet device with 3-(4-biphenyl)-4-phenyl-5-tert-butylphenyl- 1,2,4-triazole as emitter exhibits short-wavelength emission with peak of 376 nm, full-width at halfmaximum of 42 nm, maximum radiance of 3.36 mW/cm2 and external quantum efficiency of 1.5%. The performances are almost comparable to the counterparts with poly (3,4-ethylenedioxythiophene):poly (styrenesulfonate) as ABL. The current, impedance, phase and capacitance as a function of voltage characteristics elucidate that the GeO2 ABL formed from appropriate concentration of GeO2 aqueous solution favors hole injection enhancement and accordingly promoting device performance.

The prognostic significance of tumor-infiltrating lymphocytes in cervical cancer

Mengdi He,Yiying Wang,Guodong Zhang,Kankan Cao,Moran Yang,Haiou Liu 대한부인종양학회 2021 Journal of Gynecologic Oncology Vol.32 No.3

Objective: To predict the prognosis of cervical cancer, we constructed a novel model with 5specific cell types and identified a potential biomarker. Methods: We employed CIBERSORT and xCell method to evaluate the abundances of 23cells types in tumor microenvironment. Five specific cell types were filtrated to determinedifferent immunotypes by applying least absolute shrinkage and selection operator (LASSO)Cox regression method. The expression of immune checkpoints (ICPs) and effectors werevalidated by immunohistochemistry. Correlation analysis was performed to examine therelevance between PIK3CA mutational status and ICPs. Results: Unsupervised clustering of patients on the basis of tumor infiltrating lymphocytesand fibroblasts identified patients with shorter overall survival (OS) (hazard ratio[HR]=3.0729; 95% confidence interval [CI]=1.5103–6.2522; p=0.0118). An immunoscore(IS) signature consisting of 5 immune cell types infiltrating in tumor core (CD8T, activatedNK cells, neutrophils, activated mast cells, macrophages) was constructed using LASSO Coxregression analysis. Receiver operating characteristic curves confirmed that the area underthe curve of IS was significantly higher to that of International Federation of Gynecology andObstetrics staging alone (0.637 vs. 0.55). Survival analysis revealed patients in high IS groupexhibited a poorer OS (HR=3.0113; 95% CI=1.8746–4.8373; p<0.0001). The multivariateanalysis indicated the IS was an independent prognostic factor. In addition, the lower ISrelated to higher expression of ICPs and neoantigen load. Conclusions: The identification of IS in cervical cancer tissues could facilitate patient riskstratification and selection of immunotherapeutic responses, but more prospective studiesare needed to assess its reliability.