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      • A Method for Anisotropic Spatial Smoothing of Functional Magnetic Resonance Images

        Haewon Nam,Hae-Jeong Park 한국산업응용수학회 2010 한국산업응용수학회 학술대회 논문집 Vol.5 No.1

        Spatial smoothing using isotropic Gaussian kernels removes noise, reduces spatial resolution, and increases the partial volume effect of functional magnetic resonance images (fMRI), thereby reducing statistical power. To minimize these limitations, we propose a novel anisotropic smoothing method for fMRI data that is based on a classical anisotropic smoothing technique, which requires an anisotropic tensor in the volumetric space. To extract anisotropic tensor for each voxel of the functional data, the intensity gradient was first derived using the distance transformation of the segmented grey matter of the fMRI-coregistered T1-weighted image. The intensity gradient was then used to determine the anisotropic kernel for smoothing at each voxel of the fMRI data. Performance evaluations on both real and simulated data showed that this novel technique improved both statistical power and localization on the grey matter cortex. The advantages of the proposed method are that it works on the volume space and does not require any sophisticated calculations of the cortical surface, and it does not require time series data. We also presented that the current method is robust to the registration errors between T1 structural images and the fMRI data.

      • SCOPUSKCI등재
      • KCI등재후보

        정신과 환자의 성폭행 유병률 및 관련 요인

        김대호,이해원,노성원,최준호,박용천,정승아,남정현 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

        Objectives : The direct causal relationship between the experience of sexual assault and development of psychiatric disorder remains uncertain. However, studies consistently show that those with history of this horrendous event report a wide range of symptoms, higher level of distress, and various social and psychological problems. This study investigated the prevalence and associated risk factors in a cohort sample of 340 Korean psychiatric patients. Methods : Data from consecutive 340 new patients were gathered at a psychiatric department of a university affiliated hospital. Participants completed Life Events Scale, Symptom Checklist-90-R, State-Trait Anxiety Inventory, Beck Depression Inventory, and Dissociative Experiences Scale. Results : History of sexual assault was reported by 11.5% of respondents (women 18.6% ; men 2.1%). Bivariate analysis revealed that women (p<.001), divorced or widowed and never been married (p<.05), unemployed and students or housewives (p<.05), monthly income more than 2 million Won (p<.05) were associated significantly with experience of sexual assault. All the scores from the scales but Beck Depression Inventory were significantly higher for the sexually assaulted. Multiple logistic regression analysis revealed that women were 12 times more likely to be sexually assaulted (Odds ratio=12.24, 95% CI=3.51 -42.64). Other risk factors included younger age and interacdon of post-traumatic stress disorder (PTSD) and Global Severity Index. Conclusion : This study supported the risk factors of sexual assaults identified in western literature. Clinicians can be alert for any history of sexual assault when younger women with PTSD present higher level of symptomatology.

      • KCI등재후보

        초발 정신분열병 환자의 정신병 비치료기간과 관련된 정신사회적 요인

        박선철,김대호,남정현,이해원 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.4

        Objectives : This study investigated the psychosocial factors and clinical symptoms related to the duration of untreated Psychosis (DUP) in 35 consecutive first-episode inpatients with schizophrenia. Mcthods : Data from 35 schizophrenic patients were obtained from two general psychiatric inpatient units at a university medical center. These data included scores from Index of Social Position (ISP), Positive and Negative Syndrome Scale (PANSS) and Symptom Checklist-90-Revised (SCL-90-R) as well as socio-demographic informations. Rcsults : Among socio-demographic variables, lower social position (r=.610, P<.001), male sex (r=.407, P=.015), and grew up in rural area (r=.335, p=.045) were significantly correlated with DUP. The interpersonal sensitivity of SCL-90-R was the only symptomatic variable significantly correlated with DUP (r=.379, P=.027). However, after controlling interactive effects of the variables, only lower social position and interpersonal sensitivity remained significant. Lower social position was more influential on DUP than interpersonal sensitivity in the multiple regression model. Conclusion : Both social and symptomatic factors independently influenced DUP in schizophrenic patients. Lower social position defined by education and occupation of patients or caretakers may reflect barriers to psychiatric services or poor identification of mental illness. This together with patients' subjective distress in interpersonal interactions may delay the intervention of psychiatric services.

      • KCI등재

        여성 베이비부머들의 식생활 태도와 미래 식생활 요구도 조사

        남혜원,명춘옥,박영심,Nam, Haewon,Myung, Choonok,Park, Youngsim 한국식품영양학회 2013 韓國食品營養學會誌 Vol.26 No.4

        The purpose of this study is to examine female baby boomers' dietary habits and their attitudes together with their needs for future perspectives of dietary life. Our aim is to use these findings as a basic data when forecasting for food-related industries or policy making. A survey is being carried out for a total of 358 female baby boomers and analyzed by SPSS 12.0. The following is a summary of this study. The average age is 52.6 years old, most of them graduated from highschool (63.1%) and had a nuclear type of family (76.1%). Only 39.0% is composed of housewives, others had either full-time or part-time jobs. Self-assessment of stress is not so high and only 8.1% are dissatisfied with their lives. 38.2% are either overweight or obese in terms of BMI, and most of them are non-smokers (97.2%) or non-drinkers (63.0%). Their mean dietary habit scores are $70.6{\pm}11.8$, and the scores show significant relations with their education levels (p<0.01), monthly income (p<0.01), life satisfaction rates (p<0.001), stress levels (p<0.001), smoking habits (p<0.05), drinking habits (p<0.05), regular exercises (p<0.001) and regular health check-ups (p<0.05). The rate of skipping breakfast, lunch and dinner are 18.2%, 1.1%, 5.2% respectively. The main reason for skipping breakfast is the 'lack of time'. With regards to the frequency of grocery shopping, almost half of the subjects (55.7%) said '1~2 times per week' and bought mainly raw food sources such as vegetables, fruits, and meats. The majority of the subjects (91.3%) report that they cooked meals at homes, and took about 1 hour of time. The subjects also point out that cooking was a bothering task, and only 46.4% would prepare meals at home, while others would rather eat out or eat convenience foods. The main reasons for not wanting meal services in the elderly welfare facility are because they didn't want to live such places (48.4%) and the meals are tasteless (31.3%). As for delivery meal services, 60.1% are aware of it, and 39.9% would consider using it in the future. Factors to be considered when using the delivery meal service are sanitation (43.7%), nutrition (28.7%), taste (18.4%), price (6.3%), and brand name (2.9%). This study is expected to be used as useful information when developing food-related strategies for baby boomers in the future.

      • KCI등재

        베이비부머 여성들의 식생활 라이프 스타일에 따른 HMR 구매행동 및 요구도

        명춘옥,남혜원,박영심,Myung, Choonok,Nam, Haewon,Park, Youngsim 한국식품영양학회 2016 韓國食品營養學會誌 Vol.29 No.1

        The purpose of this study was to analyze the food-related lifestyle choices of female baby boomers and to investigate variables regarding home meal replacement (HMR) buying behaviors and future needs. This study was conducted on 358 female baby boomers 53 years of age living in Gyeonggi and near Seoul. Out of 420 distributed questionnaires, 358 were returned and used for analysis (response rate: 85.2%). As a result of cluster analysis, three groups were identified based on the food-related lifestyles : a value-seeking group, a convenience-seeking group, and a health-seeking group. Among the three groups, there were significant differences in two socio-demographic characteristics, education level (p<0.05) and regular exercise (p<0.01), and in several health- and food-related habits, type of breakfast (p<0.01), type of dinner (p<0.05), dinner details (p<0.05), frequency of eating out (p<0.05), and eating habits score (p<0.01). The health-seeking group was significantly more likely to purchase ready to cook (RTC) items (59.1%) than were the other groups (p<0.001). However, the ratio of HMR purchasing for the purpose of meal replacement (p<0.05) and an HMR purchasing frequency of more than twice a week (p<0.001) were significantly lower in the health-seeking group. Reasons for selecting HMR showed a similar tendency among groups in taste (26.2%), convenience (18.7%), price (16.9%), safety (15.3%) and type of food (14.3%). However, the satisfaction scores for hygiene and safety reported by the health-seeking group were significantly lower than those reported by the other groups. More than two-thirds of all respondents were willing to purchase HMR in the future, though there were significant differences according to group: convenience-seeking group, 73.1%, health-seeking group, 70.1%, and value-seeking group, 65.7% (p<0.05). Our results suggest that the number of baby boomers purchasing HMR products will continue to grow and baby boomers will want HMR products to be more healthy (52.0%), safe (28.5%) and delicious (13.4%). An emphasis on taste was high in the convenience-seeking group, whereas an emphasis on health was high in the health-seeking and value-seeking groups. In conclusion, this study shows various food-related lifestyles amongst female baby boomers and illustrates the need to develop HMR marketing strategies targeted to these different lifestyles.

      • KCI등재

        디지털 X-선 영상을 통한 치아우식증 진단 보조 시스템으로써 치아 와동 자동 검출 프로그램 연구

        허장용,남혜원,김주혜,박지만,신석영,이레나,Huh, Jangyong,Nam, Haewon,Kim, Juhae,Park, Jiman,Shin, Sukyoung,Lee, Rena 한국의학물리학회 2015 의학물리 Vol.26 No.1

        본 연구팀이 개발한 신개념 강내형 치과 진단 장치에서 촬영한 X선 치아영상으로부터 치아 우식증을 조기 단계에서 판별하고 치과의사의 정확한 진단을 돕기 위해서 병변진단 보조시스템인 치아 와동 자동 검출 프로그램을 개발하고자 하였다. 치아 와동 자동 검출 시스템을 구성하고 있는 기본 알고리즘은 치아 와동과 정상 치아를 구분 할 수 있는 영상분별 알고리즘과 치아 영상의 고유 특성 정보를 분석하고 이를 병변 검출에 적용할 수 있는 알고리즘으로 나눌 수가 있는데, 본 연구에서는 먼저, DRLSE 방법을 적용하여 병변과 정상치아 사이의 윤곽선 분할 성능을 테스트 하였다. 개발된 알고리즘의 와식 판별 성능을 테스트하기 위해서 다양한 형태의 와식을 포함하는 전치, 견치, 소구치 등의 7개의 치아팬텀을 제작하고 치아 와식 분별을 실시하였다. 총 14 개의 와식 중에 와식의 경계를 부분적으로 식별한 2개를 제외하고는 12개 와식의 경계를 정확하게 구별하여 개발된 자동 치아 병변 알고리즘의 가능성을 입증하였다. 그러나 실제 치아 와식의 형태는 개개인마다 다르고 복잡하기 때문에 무작위로 선택된 실제 치아에 적용하기 위해서는 보강된 알고리즘이 필요하다. 향후에는 치아에 대한 사전정보를 처리하고 적용하는 패턴 인식 혹은 기계학습 알고리즘을 추가하여 보다 효과적이고 정확한 병변 알고리즘으로 개선할 예정이다. The automated dental cavity detection program for a new concept intra-oral dental x-ray imaging device, an auxiliary diagnosis system, which is able to assist a dentist to identify dental caries in an early stage and to make an accurate diagnosis, was to be developed. The primary theory of the automatic dental cavity detection program is divided into two algorithms; one is an image segmentation skill to discriminate between a dental cavity and a normal tooth and the other is a computational method to analyze feature of an tooth image and take an advantage of it for detection of dental cavities. In the present study, it is, first, evaluated how accurately the DRLSE (Direct Regularized Level Set Evolution) method extracts demarcation surrounding the dental cavity. In order to evaluate the ability of the developed algorithm to automatically detect dental cavities, 7 tooth phantoms from incisor to molar were fabricated which contained a various form of cavities. Then, dental cavities in the tooth phantom images were analyzed with the developed algorithm. Except for two cavities whose contours were identified partially, the contours of 12 cavities were correctly discriminated by the automated dental caries detection program, which, consequently, proved the practical feasibility of the automatic dental lesion detection algorithm. However, an efficient and enhanced algorithm is required for its application to the actual dental diagnosis since shapes or conditions of the dental caries are different between individuals and complicated. In the future, the automatic dental cavity detection system will be improved adding pattern recognition or machine learning based algorithm which can deal with information of tooth status.

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