우골유도합성골이 세포 증식 및 염기성 인산분해 효소 활성에 미치는 영향

현하나,최희인,유형근 원광대학교 치의학연구소 2003 圓光齒醫學 Vol.12 No.2

The ultimate goal of periodontal therapy is to promote the regeneration of lost periodontal tissue, there have been many attempts to develop a method to achieve this goal, but none of them was completely successful. The purpose of this study was to evaluate the effects of BBP?? on alkaline phosphatase(ALP) activity in human fetal osteoblast (hFOB1). The results of this study were as follows, BBP?? didn't show any significant increased cell proliferation and cell activity in the human fetal osteoblast as compared to non-supplemented controls at 2 and 4 day. In ALP activity, 100 ㎍/㎖ BBP?? treated group showed significantly increased value than negative control group.

免疫組織化學的 方法에 依한 마우스組織에서의 Toxoplasma 抗原 檢出에 關한 硏究

趙裕行,李英河,羅榮彦,辛大煥 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.1

This study was performed to identify the Toxoplasma antigens from the mice tissue chronically infected with Toxoplasma gondii Beverley strain by peroxidase-antiperoxidase(PAP) method. The 21 mice divided into two groups, control group (3mice) and cortisone-treated group (18mice). In cortisone-treated group, the mice were injected with 0.5mg of cortisone acetate twice a week for 6 week subcutaneously and 3 mice were sacrified at each week. The brain, lung, heart, liver, spleen, kidney, small intestine and skeletal muscle of mice were removed immediately after death. The removed tissues were fixed with 10% buffered neutral formalin, and then PAP method and H-E staining were done. The results were obtained as follows: 1. The cysts were found in the brain entirely, in the heart at 4 weeks, and in the skeletal muscle at 5 weeks. The number and size of cysts in the brain were increased in proportion to total dose of cortisone acetate in mice. Tachyzoites of Toxoplasma gondii showed at 4, 5 and 6 week in brain. 2. The brain, speen and skeletal muscle showed highly positive immunoreactivity. The liver, heart and small intestine were moderately positive, but lung and kidney showed weekly positive immunoreactivity by PAP method. 3. There were a chronic inflammatory responses in the brain, liver and heart but the remaining organs were almost normal appearance. And tachyzoites were found in the brain, associated with severe inflammatory changes. The present study revealed that tachyzoites and immunoreactivity of Toxoplasma were easily detected by PAP immune complex method.

대학생의 쇼핑성향에 따른 백화점 의복 판매원의 평가 속성

김혜영,박하나,유연옥,이지혜,박혜선 배재대학교 자연과학연구소 2004 自然科學論文集 Vol.15 No.1

새만금 단벌기 목재에너지림 식재 포플러 묘목의 생육특성 및 바이오매스 생산량

우수영 ( Su Young Woo ),이성한 ( Seong Han Lee ),제선미 ( Sun Mi Je ),곽명자 ( Myung Ja Kwak ),유하나 ( Ha Na You ),여진기 ( Jin Kie Yeo ),전병환 ( Byoung Hwan Cheon ) 한국임학회 2014 산림과학 공동학술대회 논문집 Vol.2014 No.-

본 연구는 새만금 간척지 배후도시용 유보용지를 이용하여 2012년에 조성된 포플러 단벌기 바이오매스 생산림을 대상으로 식재 시 대절처리에 따른 묘목의 생육특성과 목질계 바이오매스 생산성을 조사하기 위해 수행되었다. 식재 2년차 목재에너지림 포플러 묘목의 총 수고와 직경은 무대절처리구(347.8cm/19.5mm)와 1m 대절 처리구(324.5cm/18mm)에서 유사한 수준이었으며, 지제부 대절처리구(259.8cm/15.1mm)에서 가장 낮은 경향을 보였다. 그러나 식재 이후 2년간 순수고생장량에 있어서는 1m 대절 처리구가 241.4cm로 가장 높았으며, 다음으로 무대절 처리구(212.7cm) 및 지제부대절 처리구(181.6cm) 순으로 나타났다. 2년 동안의 지상부 목질계 바이오매스 생산량을 추산한 결과, 무대절 처리구(약 4.3ton/ha)에서 가장 높았고, 다음으로 1m 대절 처리구(약 4.0ton/ha) 및 지제부 대절 처리구(약 2.6ton/ha) 순으로 나타났다. 고사율의 경우 1m 대절 처리구가 약 10.0%로 무대절 처리구(26.2%) 및 지제부 대절 처리구(30.1%)에 비해 현저히 낮았으며, 수관활력도 및 잎 피해도 역시 가장 양호한 것으로 조사되었다. 종합적으로 식재 후 2년 간 지상부 목질계 바이오매스의 총 생산량은 무대절 처리구에서 가장 높은 것으로 추산되었으나 간척지 환경을 고려한 적응지수는 1m 대절 처리구에서 가장 높은 것으로 평가되었다. This study was conducted to investigate the growth characteristic and wood biomass production for a short rotation coppice plantation with differently coppiced poplar established in Saemangeum reclaimed land in 2012. Total tree hight and DBH after two growing seasons were highest in non-coppiced plantation (347.8㎝/19.5㎜) followed by 1m hight-coppiced (324.5㎝/18㎜) and ground level-coppiced plantation (259.8㎝/15.1㎜). However, net growth of tree hight during the two growing seasons was highest in 1m hight-coppiced plantation (241.4㎝) followed by non-coppiced (212.7㎝) and ground level-coppiced plantation (181.6㎝). Above ground wood biomass production during the 2 years after plantation was estimated to be highest in non-coppiced plantation (about 4.3 ton/ha) followed by 1m hight-coppiced (about 4.0 ton/ha) and ground level-coppiced plantation (about 2.6 ton/ha). However, the best performance in terms of survival rate, vitality of tree crown and degree of leaf injury was showed in 1m hight-coppiced plantation. Overall adaptability concerning the environmental conditions of reclaimed land was also highest in 1m hight-coppiced plantation.

도심지내 생육환경 차이에 따른 가로수의 생리 및 생화학적 반응

유하나 ( Ha Na You ),우수영 ( Su Young Woo ),이성한 ( Seong Han Lee ),제선미 ( Sun Mi Jea ),곽명자 ( Myeong Ja Kwak ),이경은 ( Kyoung Eun Lee ),이태윤 ( Tae Yoon Lee ),조재형 ( Jae Hyung Jo ),박찬열 ( Chan Ryul Park ) 한국임학회 2014 산림과학 공동학술대회 논문집 Vol.2014 No.-

도시의 복합적인 환경오염은 가로수에 있어서 여러 가지 생리적 장해를 유발한다. 본 연구는 서울시의 대표적 가로수종인 양버즘나무(Platanus occidentalis)와 은행나무(Ginkgo biloba)를 대상으로 도심지 내 생육환경 차이에 따른 수목의 생리적 반응을 규명하고자 수행되었다. 연구 대상지는 도시 내 교통량 및 토양 환경 등을 고려하여 가로수 생육이 불량할 것으로 생각되는 곳과 양호할 것으로 생각되는 곳을 선택하였고, 수목 조사는 6월과 10월에 실시하였다. 양버즘나무와 은행나무모두 환경이 상대적으로 불량한 지역에서 총 엽록소, 카로테노이드 그리고 아스크로빈 산 함량이 낮게 나타났다. 특히 은행나무는 6월과 10월 모두 생육환경 차이에 따른 세 변수들의 유의적 차이가 크게 나타났으며, 양버즘나무는 6월에 비해 10월에 유의적 차이가 크게 나타났다. 상대 이온 유출량과 엽온은 두 수종 모두 생육환경이 불량한 곳에서 더 높게 나타나는 경향을 보였다. 반면 잎의 pH는 두수종 모두 생육환경간의 차이를 보이지 않았다. 본 실험을 통해서 도시 내 생육환경 차이가 은행나무와 양버즘나무의 생리적 활성에 영향을 미칠 수 있다는 것을 확인하였다. Urban environmental pollution induced physiological lesion on the roadside tree. This study was conducted to identify physiological responses of Platanus occidentalis and Ginkgo biloba to urban environmental conditions at two different sites in Seoul, Korea. Sites were selected based on urban environmental conditions like traffic volume and soil condition etc. Tree experimentations were performed in June and October. In both species, trees which selected at poor environment condition had low contents of total chlorophyll, carotenoid and ascrobic acid. By comparing those parameters of two species, Ginko biloba showed a significant difference in June and October, whereas Platanus occidentalis showed a significant difference in October (p<0.05). Relative ion leakage and leaf temperature of both species which selected at poor environment condition showed increasing. But there was no significant difference of leaf pH in both species. According to this study, we noticed that physiological activities of Ginkgo biloba and Platanus occidentalis could be affected by different urban environmental conditions.

서비스 청사진을 이용한 공연장 서비스 분석에 관한 연구

강하나(Kang, Ha Na),류승완(Ryu, Seung Wan),진현정(Jin, Hyun Joung),이유나(Lee, You Na) 한국서비스경영학회 2015 서비스경영학회지 Vol.16 No.1

This study tries to analyze domestic theater service processes for improvement of current services and better audiences’ satisfaction. The service blueprint method is used not only for establishment of a typical theater service process, but also for identifying critical service points affecting audiences’ satisfaction. A typical theater service process is identified as a service process diagram by identifying various front and rear support activities and functional interactions among them. In addition, several critical service points such as failure and waiting points may cause audiences’ dissatisfaction to the service. In this study, the theater service is analyzed as a service process diagram using the service blueprinting method. The results of this study will play an important role in improving quality of current theater services and its resulting audiences’ satisfaction. This study can also contribute in developing a archetypal service process of other performing arts service processes.

Possible Health Effects of Caffeinated Coffee Consumption on Alzheimer's Disease and Cardiovascular Disease

You, Dong-Chul,Kim, Young-Soon,Ha, Ae-Wha,Lee, Yu-Na,Kim, Soo-Min,Kim, Chun-Heum,Lee, Seung-Ha,Choi, Dal-Woong,Lee, Jae-Min Korean Society of ToxicologyKorea Environmental Mu 2011 Toxicological Research Vol.28 No.1

Coffee has been known to have both beneficial and harmful effects upon health. Coffee is one of the most widely consumed beverages, worldwide. Dementia/Alzheimer's disease (AD) and cardiovascular disease (CVD) are public health problems that are rapidly increasing in the aging population. Due to the high consumption of coffee, even small effects on an individual's health could have a large effect on public health. The aim of this review article is to provide an overview of previously published studies of coffee consumption on health. Herein, we focus on epidemiological and experimental findings to investigate whether coffee-drinking habits, and/or the quantity of coffee consumption, have any relationship to CVD, dementia/AD, and other chronic diseases. Although the underlying mechanisms are not fully understood, when comparing coffee drinkers with non-drinkers, moderate doses of caffeine showed protective effects against CVD and AD. We hypothesized that caffeine may be a novel therapy to treat CVD and dementia/AD.

Heritability of muscle mass in Korean parent–offspring pairs in the Fifth Korean National Health and Nutrition Examination Survey (KNHANES V)

You, Ju-Young,Kim, Yun-Jee,Shin, Woo-Young,Kim, Na-Yeon,Cho, Soo Hyun,Kim, Jung-Ha Elsevier 2018 Maturitas Vol.114 No.-

<P><B>Abstract</B></P> <P><B>Objectives</B></P> <P>Decreased muscle mass is known to be associated with several serious medical conditions. We analyzed the Fifth Korean National Health and Nutrition Examination Survey (KNHANES V, 2010–2011) to estimate the heritability of muscle mass in Korean parent-offspring pairs.</P> <P><B>Study Design</B></P> <P>Cross-sectional.</P> <P><B>Main outcome measures</B></P> <P>A total of 1233 parents (average age 57.67 ± 8.50 years) and 917 offspring (average age 29.10 ± 7.57 years) from 743 families were included in the analysis. Muscle mass was estimated based on three different indices: appendicular skeletal muscle mass (ASM) measured with a dual-energy X-ray absorptiometry (DXA), weight-adjusted ASM (SMI), and height-adjusted ASM (RASM). The heritability was estimated by employing the maximum-likelihood variance components implemented in Sequential Oligogenic Linkage Analysis Routines (SOLAR). The best-fitting model was determined out of four polygenic models. Pearson’s partial correlation coefficient was also calculated using the muscle mass indices to further study the association between father or mother and son or daughter pairs.</P> <P><B>Results</B></P> <P>The heritability estimates of the muscle mass indices ranged from 55% to 80% (all p < 0.01). The correlation coefficient of father and offspring ranged from 0.11 to 0.40, while that of mother and offspring ranged from 0.23 to 0.43 (all p < 0.01).</P> <P><B>Conclusions</B></P> <P>The heritability estimates of muscle mass in Koreans are large and significant, suggesting that parental muscle mass is an important predictor of the offspring’s muscle mass. The result implies that there may be a genetic factor partly determining muscle mass.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The heritability of muscle mass in Korean parent–offspring pairs was estimated. </LI> <LI> All three indices of muscle mass examined showed significant heritability. </LI> <LI> This is the first study of the heritability of muscle mass using a nationwide cohort in an Asian country. </LI> </UL> </P>

발아기간에 따른 단메밀과 쓴메밀의 항산화 성분 및 활성의 변화

라하나 ( Ha-na Ra ),강문경 ( Moon-kyung Kang ),유광연 ( Gwang-yeon You ),김진숙 ( Jin-sook Kim ),김기창 ( Gi-chang Kim ),최송이 ( Song-yi Choi ),김경미 ( Kyung-mi Kim ) 한국식품조리과학회(구 한국조리과학회) 2021 한국식품조리과학회지 Vol.37 No.1

Purpose: This study aimed to investigate the composition and biological activities of common and tartary buckwheat during germination, and to compare them. Methods: The effect of the germination time on vitamin C, γ-amino butyric acid (GABA), rutin and quercetin, total polyphenol and flavonoid contents were determined. Results: The vitamin C content reached a maximum on the fifth germination day. As the time of germination increased, the GABA content of the tartary and common buckwheat increased from 2.49 μ g/100 g and 9.59 μg/100 g to 25.17 μg/100 g and 57.84 μg/100 g, respectively. D-chiro-inositol (DCI) is a bioactive compound that serves as a mediator of insulin action. DCI in common and tartary buckwheat was found to be 129.65, 76.31 mg/100 g, respectively, with a significant increase in the DCI content as germination progressed. During germination, the total polyphenol and flavonoid contents tended to increase as germination time increased. The ABTS and DPPH radical scavenging activities in germinated samples increased with germination time and were caused by an increase in their anti-oxidative activities. Moreover, the results showed that the vitamin C and GABA content of the common buckwheat samples were higher than those of the tartary buckwheat samples with the changing trends of total polyphenols and flavonoids opposite to each other. Conclusion: It may be concluded that germinated buckwheat can find a unique use as a natural health product due to the presence of bioactive compounds with health benefits.

Magnetic Ion Doping Effects on Topological Insulator Bi₂Se₃

Young Ha Choi,Na Hyun Cho,Kyu Joon Lee,Jung Bum Yoon,Chun-Yeol You,Myung-Hwa Jung 한국자기학회 2010 한국자기학회 학술연구발표회 논문개요집 Vol.2010 No.12