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      • KCI등재

        육계사료와 식용유 정제 폐백토(Spent Bleaching Clay) 급여가 육계의 생산성에 미치는 영향

        전해열,손장호,이길왕,김선구,강한석,신택순,조병욱,Jeon H. Y.,Son J. H.,Lee K. W.,Kim S. K.,Kang H. S.,Shin T. S.,Cho B. W. 한국가금학회 2005 韓國家禽學會誌 Vol.32 No.4

        본 연구는 Spent Bleaching Clay(SBC)를 육계사료의 에너지 공급원으로 활용 가능성을 구명하기 위하여 실시하였다. 부화 직후의 120수의 병아리(한협 3호)를4처리 3반복, 반복당 10수(암수 각각 5수씩)를 Control(T1) 사료에 SBC를 $2.0\%(T2),\;4.0\%(T3)$ 및 $6.0\%(T4)$ 첨가한 4처리로 배치하였다. 시험사료 급여전 1주일은 시판사료를 급여하였다. 4주간의 시험 기간동안 증체중 및 사료 섭취량은 T3 및 T4 처리구에서 증가하는 경향이 인정되었다. 사료효율은 T3구에서 개선되는 경향이 인정되었다. 가슴살 및 다리살에서 치방산 조성을 사료의 처리에 따른 효과는 인정되지 않았다. 육계 초기 및 후기 사료 급여시 모두, 사료중의 건물, 조단백질 및 조지방 이용율은 T4 처리구가 다른 처리구에 비해서 유의하게 감소하였으며(p<0.05), 대사에너지가도 T4 처리구가 다른 3구에 비해서 유의하게 저하하였다(p<0.05). 사료중의 조회분의 이용율은 사료의 처리에 따른 차이는 인정되지 않았다. 결론적으로 본 시험의 결과 육계사료에 $2\~4\%$의 SBC첨가는 육계의 성장 및 사료효율 개선의 가능성이 있음이 사료된다. This study was conducted to evaluate the feasibility of spent bleaching clay(SBC) as an energy resource for meat type chicks. A total of one hundred twenty 1-d old broiler chicks(Han-hyop, No. 3) were divided into four groups and each group was assigned to one of the following diets: 0(T1), 2.0(T2), 4.0(T3) and $6.0\%$ SBC(T4). Each treatment had 3 replications of 10 birds. Before feeding experimental diets, they were fed a commercial diet for a week Body weight gain and feed intake tended to increase in T3 and T4, respectively. Feed efficiency(feed intake/ gain) tended to decrease in T3 compared to other groups. Fatty acid composition of breast and thigh meat was not significantly affected by feeding SBC. Utilization of dry matter, energy, crude protein and crude fat was lower in T4 than in the other groups during both starter and finisher periods(p<0.05). Crude ash utilization was not significantly affected by feeding dietary SBC. These results indicate that broiler diets may be supplemented with 2 to $4\%$ SBC without adverse effect on growth.

      • KCI등재

        육계분 발효사료의 첨가수준이 숫꽃사슴의 소화율, 건물채식량 및 질소출납에 미치는 영향

        전병태,곽완섭,강성기,이상무,문상호 한국동물자원과학회 2003 한국축산학회지 Vol.45 No.1

        본 실험은 기존 사슴사료에 있어서 육계분 발효사료의 대체 가능성을 검토하기 위해 숫사슴에 있어서 육계분 발효사료의 첨가수준을 0, 15 및 30%로 달리하여 소화율, 증체량, 건물채식량 및 질소출납에 미치는 영향을 검토하였다. 모든 처리구에서 실험사슴들은 비슷한 수준의 채식량을 나타내어 건물기준으로 체중의 약 3% 정도의 채식량을 기록하고 있어 육계분 발효사료를 30%까지 첨가한 경우 숫사슴의 채식 기호도에는 부정적인 영향이 나타나지 않는 것으로 판단되었다. 건물소화율은 Control이 76.5%로 가장 높았고, T2가 70.3%로 가장 낮아 유의성(P<0.05)이 인정되었다. 조단백질의 경우도 Control구가 75.8%로 가장 높은 소화율을 나타내었으며, T2가 70.2%로 가장 낮은 소화율을 나타내어 처리간에 유의성(P<0.05)이 인정되었다. 조섬유 소화율은 Contol구 70.8%, T1구 62.7%, T2구 56.0%로 육계분 발효사료의 첨가수준이 높아짐에 따라 조섬유 소화율이 저하되어 Control구와의 사이에 유의성(P<0.05)이 인정되었다. 건물 및 가소화 건물섭취량 모두 육계분 발효사료의 첨가수준이 높아질수록 약간씩 저하되는 경향은 있었으나 그 차이에 대한 유의성은 인정되지 않았다. 실험사슴들의 일당 증체량은 T1구에서 가장 높았으며 Control구에서 가장 낮았으나 처리간의 차이는 유의성이 인정되지 않았다. 질소섭취량은 T1구가 40.2g으로 가장 많았으며 T2구가 38.0g으로 가장 낮았으나 처리간의 유의성은 인정되지 않았다. 분 중 질소의 양은 T2구에서 가장 높았으며 뇨 중 질소의 양은 Control구가 가장 높았다(P<0.05). 체내 질소 축적량은 T1구에서 가장 높았으나 나머지 처리구들과 비슷한 수준을 유지했다. To determine nutritive value and suitability of deep-stacked broiler litter for deer, influence of supplementary levels of broiler litter on digestibility, dry matter intake, and nitrogen balance was investigated in male spotted deer (Cervus nippon) fed a commercial mixed(complete) ration. The deep-stacked and ground broiler litter was supplemented at the level of 0%(Control). 15%(TI) and 30%(T2) on the basis of fresh matter to the mixed ration. All treatments had similar palatability at about 3% body weigh of dry matter intake. Dry matter digestibility was highest in Control and lowest in T2(P<0.05). Digestibility of crude protein was lowest(P<0.05) in T2. Dry matter and digestible dry matter intake was similar in all treatments. Daily body weight gain was not affected by treatments. Feeding 15 or 30% of broiler litter to male deer resulted in similar nitrogen intake. fecal nitrogen excretion and daily nitrogen retention(g/d), compared with feeding Control. These results suggest that up to 30% of broiler litter may be fed to male deer without deleterious effects on deer performance.

      • KCI우수등재

        Sorghum × Sudangrass hybrid 의 입모저장에 관한 연구 ; 1 . 입모저장기간이 생육특성 및 기호성 변화에 미치는 영향

        이상무 ( S M Lee ),문상호 ( S H Moon ),백인철 ( I C Baek ),전병태 ( B T Jeon ) 한국축산학회 1994 한국축산학회지 Vol.36 No.1

        Growth characteristics and palatability by different harvesting dates were measured in order to determine its availability and effective storage period when sorghum × sudangrass hybrid were stored as foggage. Experiment was carried out with six treatments as follows; T1, T2 and T3 were foggaged at 120, 160 and 200㎝ in plant length and T4, T5 and T6 were foggaged at boot, milk and dough stage on 7 october after regrowth respectively. Rice straw was offered to examine the relative palatability a, control. 1. Growth characteristics such as plant length, leaf length, leaf width, leaf number and stem hardness were decreased with prolongation of foggage period at all treatments. Especially, decrease and falling ratio were a heigher at T5 and T6 than the other treatments. 2. Greeness grade of leaf showed fast decoloration at TI and T2 treatments, but stem showed fast decoloration at TS and T6 treatments. Leaf and stem decolorized in mid-October and mid-november in all treatments. 3. Leaf ratio was deceased with prolongation of foggage period, but stem showed gradually increase. Grain ratio was stable increase at T6 treatments, but not at T5 treatment, 4. Dry matter contents of leaf and grain were stable increased at all treatment but stem was multifarious according to weather conditions. 5. Changes of palatability were high at T1, T2 and T3 treatments untill mid-October, but T4 treatment and rice straw showed high in early December. 6. According to the results obtained in this study, it was suggested that when sorghum x sudangrass hybrid is used as foggage, foggaging period would be suitable until mid-november and growth stage for foggaging would be recommendable from T2 to boot stage for maximum availability.

      • Thymol from Thymus quinquecostatus Celak. protects against tert-butyl hydroperoxide-induced oxidative stress in Chang cells

        Kim, Y. S.,Hwang, J. W.,Kang, S. H.,Kim, E. H.,Jeon, Y. J.,Jeong, J. H.,Kim, H. R.,Moon, S. H.,Jeon, B. T.,Park, P. J. Springer Science + Business Media 2014 Journal of Natural Medicines Vol.68 No.1

        The present work describes the protective effects of thymol isolated from Thymus quinquecostatus Celak. against tert-butyl hydroperoxide (t-BHP)-induced oxidative damage through various experiments with Chang liver cells. Thymol significantly protected hepatocytes against t-BHP-induced cell cytotoxicity as demonstrated by increased viability. Furthermore, observation of Hoechst staining, annexin V/PI staining, and expression of Bcl-2 and Bax indicated that thymol inhibited t-BHP-induced Chang cell damage. Further, thymol inhibited the loss of mitochondrial membrane potential in t-BHP-treated Chang cells and prevented oxidative stress-triggered reactive oxygen species (ROS) and lipid peroxidation (malondialdehyde, MDA). Thymol restored the antioxidant capability of hepatocytes including glutathione (GSH) levels which were reduced by t-BHP. These results indicated that thymol prevents oxidative stress-induced damage to liver cells through suppression of ROS and MDA levels and increase of GSH level.

      • Association between insulin resistance and impairment of FGF21 signal transduction in skeletal muscles

        Jeon, J. Y.,Choi, S. E.,Ha, E. S.,Kim, T. H.,Jung, J. G.,Han, S. J.,Kim, H. J.,Kim, D. J.,Kang, Y.,Lee, K. W. Springer Science + Business Media 2016 Endocrine Vol.53 No.1

        <P>Fibroblast growth factor (FGF) 21, was identified as a potent metabolic regulator of glucose and lipid metabolism. We investigated whether the levels and signalings of FGF21 changed in the skeletal muscle of type 2 diabetes mellitus (T2DM) patients, participants with impaired glucose tolerance (IGT), human skeletal muscle myotubes (HSMMs) under insulin-resistant conditions, and mice with diet-induced obesity (DIO). A percutaneous biopsy sample of the vastus lateralis muscle of T2DM patients, IGT subjects, and participants with normal glucose tolerance was obtained and the levels and signalings of FGF21 were assessed. We determined whether the expression and signalings of FGF21 in HSMMs altered according to palmitate concentrations and exposure time. Also, we confirmed whether changes of FGF21 signal transduction resulted in the alteration of FGF21 functions. DIO mice were treated intravenously with recombinant FGF21, and the levels and signalings of FGF21 were assessed in their soleus muscles. We checked whether or not FGF21 played a role in the gene transcription related to lipid oxidation. Levels of FGF21 increased, whereas levels of phosphorylated FGF receptor (p-FGFR), phosphorylated FGFR substrates 2 alpha (p-FRS2 alpha), and phosphorylated extracellular signal-regulated kinases (p-ERK) decreased in the skeletal muscle of both T2DM patients and IGT subjects. In vitro, palmitate increased the levels of FGF21 and significantly reduced the levels of beta-klotho, p-FGFR, p-FRS2 alpha, and p-ERK1/2 in HSMMs exposed to palmitate. Palmitate also decreased glucose uptake and glycogen contents of FGF21. Consistently, the levels of FGF21 were significantly higher and the levels of beta-klotho and p-FGFR were lower in the DIO mice than in normal lean mice. The levels of FGF21 increased but its signal transduction and actions were impaired in skeletal muscles of T2DM patients, IGT subjects, in insulin-resistant HSMMs, and DIO mice.</P>

      • Protection of Mice against <i>Mycobacterium tuberculosis</i> Infection by Immunization with Aqueous Fraction of Triton X-100-soluble Cell Wall Proteins

        Jeon, B.-Y.,Kim, H.-J.,Kim, S.-C.,Jo, E.-K.,Park, J.-K.,Paik, T.-H.,Kim, S.-J.,Cho, S.-N. Blackwell Publishing Ltd 2008 Scandinavian journal of immunology Vol.67 No.1

        <P>Abstract</P><P>The aqueous fraction of Triton X-100-soluble proteins (TSP-Aq) of <I>Mycobacterium tuberculosis</I> cell wall was reported to stimulate T-cell responses in peripheral blood monocytes from tuberculosis (TB) patients and to induce Th1 cytokines, suggesting presence of protective antigens. In this study, therefore, we examined the protective efficacy of TSP-Aq against <I>M. tuberculosis</I> infection in a mouse model. C57BL/6 mice were immunized with TSP-Aq or culture filtrate proteins (CFP) mixed with incomplete Freund’s adjuvant or with BCG followed by i.v. challenge with <I>M. tuberculosis</I> H37Rv. TSP-Aq induced strong interferon-&ggr; production by spleen cells, and mice immunized with TSP-Aq antigens gave a significant reduction in <I>M. tuberculosis</I> CFU counts by 1.17–1.32 log<SUB>10 </SUB>CFU in the lungs and 1.31–2.08 log<SUB>10</SUB> CFU in the spleen from 6 to 28 weeks. The degree of protection offered by TSP-Aq was comparable to that of CFP and of the BCG vaccine. The results demonstrated that the TSP-Aq antigens confer a significant level of protection against the growth of the organism in the lungs and spleen in a mouse model of TB and indicate that TSP contains major protective antigens of <I>M. tuberculosis</I>. </P>

      • 15-lipoxygenase metabolites play an important role in the development of a T-helper type 1 allergic inflammation induced by double-stranded RNA

        Jeon, S. G.,Moon, H.-G.,Kim, Y.-S.,Choi, J.-P.,Shin, T.-S.,Hong, S.-W.,Tae, Y.-M.,Kim, S.-H.,Zhu, Z.,Gho, Y. S.,Kim, Y.-K. Blackwell Publishing Ltd 2009 Clinical and experimental allergy Vol.39 No.6

        <P>Summary</P><P>Background</P><P>We recently demonstrated that the T-helper type 1 (Th1) immune response plays an important role in the development of non-eosinophilic inflammation induced by airway exposure of an allergen plus double-stranded RNA (dsRNA). However, the role of lipoxygenase (LO) metabolites in the development of Th1 inflammation is poorly understood.</P><P>Objective</P><P>To evaluate the role of LO metabolites in the development of Th1 inflammation induced by sensitization with an allergen plus dsRNA.</P><P>Methods</P><P>A Th2-allergic inflammation mouse model was created by an intraperitoneal injection of lipopolysaccharide-depleted ovalbumin (OVA, 75 μg) and alum (2 mg) twice, and the Th1 model was created by intranasal application of OVA (75 μg) and synthetic dsRNA [10 μg of poly(I : C)] four times, followed by an intranasal challenge with 50 μg of OVA four times. The role of LO metabolites was evaluated using two approaches: a transgenic approach using 5-LO<SUP>−/−</SUP> and 15-LO<SUP>−/−</SUP> mice, and a pharmacological approach using inhibitors of cysteinyl leucotriene receptor-1 (cysLTR1), LTB4 receptor (BLT1), and 15-LO.</P><P>Results</P><P>We found that the Th1-allergic inflammation induced by OVA+dsRNA sensitization was similar between 5-LO<SUP>−/−</SUP> and wild-type (WT) control mice, although Th2 inflammation induced by sensitization with OVA+alum was reduced in the former group. In addition, dsRNA-induced Th1 allergic inflammation, which is associated with down-regulation of 15-hydroxyeicosateraenoic acids production, was not affected by treatment with cysLTR1 or BLT1 inhibitors, whereas it was significantly lower in 12/15-LO<SUP>−/−</SUP> mice compared with WT control mice. Moreover, dsRNA-induced allergic inflammation and the recruitment of T cells following an allergen challenge were significantly inhibited by treatment with a specific 15-LO inhibitor (PD146176).</P><P>Conclusion</P><P>15-LO metabolites appear to be important mediators in the development of Th1-allergic inflammation induced by sensitization with an allergen plus dsRNA. Our findings suggest that the 15-LO pathway is a novel therapeutic target for the treatment of virus-associated asthma characterized by Th1 inflammation.</P>

      • 忠州·中原地域에 있어서 導入 수수×수단그라스系 雜種의 生産性과 適應性에 關한 硏究

        全炳台,李相武,文相鎬,金星雨 건국대학교 부설 중원인문연구소 1989 論文集 Vol.8 No.-

        本 實驗은 忠州ㆍ中原地域에 있어서 生産性과 適應性이 높은 品種을 선발할 목적으로 建國大學校 自然科學大學 飼料圃場에서 수수 x 수단그라스系 雜種 9品種을 公試品種으로 하여 諸形質,靑草 및 乾物收量을 비교 검토하였다. 1. NC 855과 T.E-haygrazer品種이 다른 品種보다 草長이 높았으며, Super Gazer는 가장 짧은 형태를 보였다. 2. 다른 品種에 비하여 總葉瀑은 Sordan 79 가 174.9mm로 가장 높았으며, Super Grazer와 Pioneer 988도 165mm 以上의 높은 葉幅을 나타냈다. 수수 x 수단그라스계 雜種의 總경의 굴기는 41.9mm-47.7mm였으며, 특히 Super Grazer는 50.7mm로 높게 나타났다. 總 葉長은 Garst 757이 가장 높았다. 3. 總飼草生産에 대한 평균 葉以率은 FP4 Hybrid가 38%로 가장 높았으며, Super Grazer, Pioneer 988과 Sordan 79도 35% 以上의 높은 葉以率을 갖고 있다. 4. 수수 x 수단그라스계 雜種의 平均 분얼구 1.9-3.2個이며 Sordan 79, Grast 757 Pioneer 988은 2.9-3.1個이었다. 특히 GW 9110G는 3.4個로 가장 높았다. 5. Pioneer 988과 sordan 79가 Super Grazer보다 生草收量 乾物收量이 많았으며(P<0.01) Super Grazer가 乾物收量이 가장 낮았다 (P<0.01). G83F, NC855, FP4, T. E.haygraxer, GW 9110G 品種도 ha당 17,000kg 以上의 높은 收量을 보여주었다. 本 實驗의 結果를 종합하여 볼 때 수수 x 수단그라스계 雜種 중 Pioneer 988과 Sordan 79가 收量이 가장 우수하며 忠州, 中原地域에서 청예용 수수 x 수단그라스계 雜種의로 인정되었다. In order to select the forage of high productivity suited for soiling in Jungweon and Cjungju are, the yield perfomance and the growth characteristics of 9 introduced Sorghum-Sudangrass hybrids, were evaluated at collage of natural science of Kon-Kuk University in Chungju, 1. NC855 and T. E-haygrazer were taller than the other species, whill Super Grazer was the shortest type. 2. Total leaf width to the other species of Sordan 79 was the highest(174.9mm), and also those of Super Grazer and Pioneer 988 were over 165mm, Total stem diameter of Sorghum x Sudangrass hybrids were ranged from 41.9mm to 47.4mm and especially Super Grazer was 50.7mm, and total leaf lengh was the highest in Garst 757. 3. average D.M. proportion(%)ato the total forage yield of Fp4 hybrid was the hightest(38%)and also these of Super Grazer, Pioneer 988 and Sordan 79 had high over 35%. 4. Average new had number of Sorghum x Sudangrass hybrids were ranged from 1.9 to 3.2 and average new bud number of Sordan 79, Garst 757 and Pioneer 988 were ranged from 2.9 to 3,1 and GW 9110G was this the highest(3.4). 5. Pioneer 988 and Sordan 79 produced more fresh weight and dry matter than Super Grazer (P<0.01). Dry matter yield of Super Grazer was the lowest (P<0.01). G83F, NC855, FP4, T. E-haygrazer and gW 91110G also showed high yield over 17,000kg dry matter per ha. As the resulte of this experiment it indicated that Pioneer 988 and sordan 79 are the most excellent hybrids among selected Sorghum x Sudangrass hybrids for Summer Forage production.

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