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      • 치수절단술에 사용되는 약제가 백서 치배 및 치배주위조직세포에 미치는 영향에 관한 ^3H-thymidine을 이용한 자기방사법적인 연구

        박경주,이종헌,임창윤 단국대학교 치의학연구소 1992 논문집 Vol.4 No.-

        Formocresol(FC) had been widely used as medicament for pulpotomy, but because FC have strong toxicity, carcinogenic potential, and strong diffusible properties in tissues, Glutaraldehyde, another medicament for pulpotomy was greatly presented by many investigators and practitioners. Although many investigators had studied difference of two medicament's effects on periodontal tissues and tooth germ, there were no manuscripts of cellular activity about these medicaments applied to teeth, but there were almost clinical, histopathological studies. Especially in the investigative effects on tooth germ, the results were controversal. Thus to investigate about effects on cellular actiity of perigerminal tissue and tooth germ of rat, author presented the cellular activity and the pathologic change through calculating Thymidine labelling index(TLI) from autoradiographic technique using 3H-thymidine after these medicaments were applied to tooth. The obtained results were as follows. 1. Inflammation was initiated after one week of FC and two weeks of GA. It was thought that diffusible property of GA was lesser than that of FC. 2. In group treated with FC, inflammation, vasodilation and bone destruction continuously increased for all periods of experiment and the feature of 8 weeks was very severe. But in group treated with GA, inflammation, vasodilation and bone destruction slightly incresed for all period of experment. 3. TLI was increased after two weeks of FC, but decreased after four weeks because of different accumulative concentration between 2 and 4 weeks. 4. GA treated group which did not show the change of the cellular activity of perigerminal tissue and tooth germ presented the slight effects on these cells. 5. Changes of cellular activities in FC treated group did not result from inflammation, but formocresole's property itself. And bone destruction was derived from secondary effects of inflammation. 6. The fact that FC arose severe inflammation and change of cellular activity reflected that FC might affected

      • Carbon tetrachloride를 투여한 rat의 hepatic lipid 축적에 미치는 vitamin E의 효과에 관한 연구

        박은주,이경연,이미영,이외숙,장재정,정귀은,최진희 曉星女子大學校 藥學大學 學生會 1988 曉星藥誌 Vol.4 No.-

        The present studies were undertaken to evaluate the effect of vitamin E, CCl_4 on the change of hepatic triglyceride, hepatic cholesterol, hepatic phospholipid in male rat. The result obtained from this study were summarised as follows: 1. Hepatic phospholipid of CCl_4 treated rat was increased in proportion to CCl_4 dosage but after concomitant injection(I.P) of vitamin E and CCl_4, hepatic phospholipid was significantly decreased in comparison to that of CCl_4 alone injection. 2. There was no effect on hepatic cholesterol concentration either CCl_4 alone injection(I.P) or concomitant injecton(I.P) of vitamin E and CCl_4. 3. Hepatic triglyceride of CCl_4-treated rat was significantly increased in comparison to that of normal rat but hepatic triglyceride of rat concomitant injection of vitamin E and CCl_4 was significantly decreased in comparison to that of CCl_4 alone injection.

      • ABS AH 32鋼의 熔接金屬에서 低溫 龜裂 感受性에 미치는 豫熱效果

        鄭潾相,朴景采,金庚周 경북대학교 공과대학 1987 工大硏究誌 Vol.16 No.-

        It is known that the occurrence of cold cracking in welded materials is influenced by restraint, diffusible hydrogen and microstructure of weldments. The purpose of this work is to investigate effects of preheating in the same humidity of electrode as well as influences of diffusible hydrogen content. The results of obtained are as follows : Thermal cycles in welments were changed by preheating temperatures and particularly, t_8/5(cooling time from 800℃ to 500℃) and t_100(colling time from solidification to 100℃) were increased according to increase of predeating temperture. First of all. in the same humidity of dried electrode, when specimens we welded at ambient temperature, weld cracking percentages for surface and root were 100%, but when 150℃, no cracking was occurred. In the view of hardness distribution, hardness of HAZ were higher than those of base metal and weld metal and were in inverse proportion to preheating temperature and thickness of HAZ. Secondly, in the same preheating temperature, when specimens were welded in the various humidity of electrode, regardless of humidity of electrode, surface cracks were not occurred. With increasing diffusible hydrogen content, root cracking percentages increased slightly, but hardness distribution and thickness of HAZ were not changed.

      • GLASS/UP系 複合材料의 破壞에 미치는 NOTCH平徑의 影響

        김귀식,박경석,오맹종,김주봉 濟州大學校工科大學附屬産業技術硏究所 1992 尖端技術硏究所論文集 Vol.3 No.-

        This study is investigated by experimental method and FEM about the effect of notch root radious(ρ) on the fracture of GFRP. The smaller ρshowed the fracture behavior which was mainly caused by the propagation of the stable crack, but the fracture behavior in the larger ρwas mainly caused by the spread of damage. The experimental value of the nominal stress could be estimated by FEM simulation and the load-displacement curve could also be drawn. According to the results simulated damage zone by FEM, as the ρis smaller, the damage begin at low stress.

      • Maillard 反應에 關한 硏究 : Ⅴ. 反應溫度 및 時間이 skim milk의 Maillard reaction에 미치는 영향 Ⅴ. Effects of reaction temperature and time on the Maillard reaction by heating skim milk

        李乙熙,朴玉潤,徐珠銖,高鏡畢 진주산업대학교 농업기술연구소 1993 農業技術硏究所報 Vol.6 No.-

        The color intersities of melanoidins and the contents of HMF in skim milk by heat treatment. The contents of HMF in skim milk were detected in all heat-treated skim milk by colormetrical method and HPLC method. The color intensities of melanoidins showed significant dependence on reaction temperature and time. The contents of HMF in skim milk were detected in all heat treated skim milk by colormetrical method. While they were not detected by HPLC method when skim milk was heated at the temperature 70℃ for 30, 50 and 70 minutes. It showed significant dependence of reaction temperature and time.

      • GLASS/UR계 복합재료의 파괴에 미치는 NOTCH반경의 영향

        김귀식,오맹종,박경석,김주봉 濟州大學校 工科大學 産業技術硏究所 1992 産業技術硏究報告 Vol.3 No.-

        This study is investigated by experimental method and FEM about the effect of notch root radious(ρ) on the fracture of GFRP. The smaller ρ showed the fracture behavior which was mainly caused by the propagation of the stable crack, but the fracture behavior in the larger ρ was mainly caused by the spread of damage. The experimental value of the nominal stress could be estimated by FEM simulation and the load-displacement curve could also be drawn. According to the results simulated damage zone by FEM. as the ρ is smaller, the damage begin at low stress.

      • KCI등재

        과민성 장 증후군의 증상 경감을 위한 비약물적 접근 고찰

        최명애,김금순,안경주,채영란,최정안,홍해숙,박미정,이경숙,신기수,정재심 대한기초간호자연과학회 2005 Journal of korean biological nursing science Vol.7 No.2

        There have been many trials of clinical efficacy of multicomponent and single component treatments for irritable bowel syndrome(IBS). We reviewed effects of non phamacological treatments in the IBS. Though the efficacy of multi-component approaches was unclear, several results suggest that cognitive behavioral therapy was effective in improving gastrointestinal symptoms of IBS. As a single component, cognitive therapy and relaxation with or without biofeedback could improve the symptoms and psychological health of IBS patients. Yoga, meditation, self-help information and hypnotherapy could be applicable to IBS.

      • KCI등재

        Immunostimulatory Activity of Hibiscus syriacus L. Leaves in Mouse Macrophages, RAW264.7 cells, and Immunosuppressed Mice

        Na Gyeong Geum(Na Gyeong Geum),Ju Hyeong Yu(Ju Hyeong Yu),So Jung Park(So Jung Park),Min Yeong Choi(Min Yeong Choi),Jae Won Lee(Jae Won Lee),Gwang Hun Park(Gwang Hun Park),Hae-Yun Kwon(Hae-Yun Kwon),J 한국자원식물학회 2022 한국자원식물학회지 Vol.35 No.6

        Under the COVID-19 pandemic, interest in immune enhancement is increasing. Although the immune-enhancing activity of plants of the genus Hibiscus has been reported, there is no study on the immune-enhancing activity of H. syriacus. Thus, in this study, we investigated the immune-enhancing activity of Hibiscus syriacus leaves (HSL) in mouse macrophages, RAW264.7 cells, and immunosuppressed mice. HSL increased the production of immunostimulatory factors such as nitric oxide (NO), inducible nitric oxide synthase (iNOS), interleukin-1β (IL-1β), and tumor necrosis factor-α (TNF-α) and activated the phagocytosis in RAW264.7 cells. The HSL-mediated production of immunostimulatory factors was dependent on toll-like receptor 4 (TLR4), p38, and c-Jun N-terminal kinase (JNK) in RAW264.7 cells. In the immunosuppressed mouse model, HSL increased the spleen index, the levels of the cytokines, and the numbers of lymphocytes, neutrophils, and monocytes. Taken together, HSL may be considered to have immune-enhancing activity and be expected to be used as a potential immune-enhancing agent.

      • A Facile Route for Patterned Growth of Metal–Insulator Carbon Lateral Junction through One-Pot Synthesis

        Park, Beomjin,Park, Jaesung,Son, Jin Gyeong,Kim, Yong-Jin,Yu, Seong Uk,Park, Hyo Ju,Chae, Dong-Hun,Byun, Jinseok,Jeon, Gumhye,Huh, Sung,Lee, Seoung-Ki,Mishchenko, Artem,Hyun, Seung,Lee, Tae Geol,Han, American Chemical Society 2015 ACS NANO Vol.9 No.8

        <P>Precise graphene patterning is of critical importance for tailor-made and sophisticated two-dimensional nanoelectronic and optical devices. However, graphene-based heterostructures have been grown by delicate multistep chemical vapor deposition methods, limiting preparation of versatile heterostructures. Here, we report one-pot synthesis of graphene/amorphous carbon (a-C) heterostructures from a solid source of polystyrene <I>via</I> selective photo-cross-linking process. Graphene is successfully grown from neat polystyrene regions, while patterned cross-linked polystyrene regions turn into a-C because of a large difference in their thermal stability. Since the electrical resistance of a-C is at least 2 orders of magnitude higher than that for graphene, the charge transport in graphene/a-C heterostructure occurs through the graphene region. Measurement of the quantum Hall effect in graphene/a-C lateral heterostructures clearly confirms the reliable quality of graphene and well-defined graphene/a-C interface. The direct synthesis of patterned graphene from polymer pattern could be further exploited to prepare versatile heterostructures.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/ancac3/2015/ancac3.2015.9.issue-8/acsnano.5b03037/production/images/medium/nn-2015-03037u_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nn5b03037'>ACS Electronic Supporting Info</A></P>

      • KCI등재

        A Comparison of Shoulder Muscle Activities on Sitting Posture and Shoulder Angle

        Gyeong-ju Park,Sun-young Park,Eun-jae Lee,Su-hyeon Jeong,Su-jin Kim 한국전문물리치료학회 2018 한국전문물리치료학회지 Vol.25 No.1

        Background: Sitting posture influences movements of scapulothoracic and glenohumeral joints and changes the shoulder muscle activities. The development and maintenance of correct sitting posture is important for the fundamental treatment of shoulder pain during rehabilitation. Objects: The purpose of this study was to investigate the effects of the sitting postures and the shoulder movements on shoulder muscle activities for both male and female. Methods: Twenty-eight subjects without shoulder-related diseases participated in this experiment. The subjects had randomly adopted three different sitting postures (upright posture, preferred posture, maximum slouched posture) and shoulder flexion angles in scapular plane (30 ˚ , 90 ˚ , 120 ˚ ). Surface electrodes were collected from upper trapezius (UT), anterior deltoid (AD), and posterior deltoid (PD) and the active shoulder range of motion was measured in each sitting posture and shoulder flexion angle. Results: The active range of motions of the shoulder external rotation and the flexion in the scapular plane decreased from the upright posture to the maximum slouched posture (p<.05, mixed-effect linear regression with random intercept, Tukey post-hoc analysis). All muscles showed the highest EMG activities at 120 ˚ shoulder flexion with the maximum slouched posture and did not show the gender differences. Conclusion: Increased shoulder muscle activities may become the potential risk factor for the shoulder impairment and pain if people continuously maintain the maximum slouched posture. Therefore, an upright position is necessary during shoulder exercises, as well as in activities of daily living, including motions involving lifting the arms.

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