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RISS 인기검색어
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Detail-Enhanced Medical Image Fusion in NSCT Domain
Guocheng Yang,Leiting Chen,Meiling Li 보안공학연구지원센터 2015 International Journal of Multimedia and Ubiquitous Vol.10 No.8
Multimodal medical image fusion technique plays an important role in clinical applications, such as pathologic diagnosis and surgical options. However, many traditional fusion methods cannot well preserve details of source images in the fused image. To address this problem, a detail-enhanced image fusion scheme based on non-subsampled contourlet transform (NSCT) and gain control (i.e., NCGC) is developed in this paper, which can effectively combine the spectral information and the spatial features of source images. The proposed method applies power law transformation to tune coefficients of each decomposed subband, and adjusts the strength of subband signals by smooth gain control. Eventually, the fused image with more anatomical details and functional information is constructed by the inverse NSCT. Three pairs of medical images with different modalities and three fusion metrics are applied to validate the feasibility of this algorithm. Experimental results demonstrate that the proposed method can achieve superior performance in both visual perception and objective assessment.
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Effects of rolling-cutting processing parameters on micro-grooved strips forming
Baoyu Zhang,Xianqi Fan,Guocheng Shi,Yang Zhou,Di He,Wenjun Deng 대한기계학회 2021 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.35 No.1
High heat flux density in the micro-electronics field urges the demand for functional surface for heat transfer. Micro-grooved surface is the classical heat transfer surface because of the larger specific area and better inducement of turbulence. A novel micro-grooved surface manufacturing process, the rolling-cutting process, is proposed to produce microgrooved strips. Experiments are conducted to analyze the influence of processing parameters on the strips forming. The optimal combination of processing parameters is given to attain the micro-grooved strips with higher fins height and thinner base thickness. Additionally, the obtained strips are of three-dimensional structures with serrated bulges at the top. The difference between the material flow of serrated bulges and strip base is discussed, and the forming of serrated bulges is mainly due to inhomogeneous sinuous material flow.
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Metabolic Engineering of Saccharomyces cerevisiae to Improve Glucan Biosynthesis
( Xing Zhou ),( Jing He ),( Lingling Wang ),( Yang Wang ),( Guocheng Du ),( Zhen Kang ) 한국미생물생명공학회(구 한국산업미생물학회) 2019 Journal of microbiology and biotechnology Vol.29 No.5
β-Glucan is a chief structural polymer in the cell wall of yeast. β-Glucan has attracted intensive attention because of its wide applications in health protection and cosmetic areas. In the present study, the β-glucan biosynthesis pathway in S. Cerevisiae was engineered to enhance β-glucan accumulation. A newly identified bacterial β-1, 6-glucan synthase GsmA from Mycoplasma agalactiae was expressed, and increased β-glucan content by 43%. In addition, other pathway enzymes were investigated to direct more metabolic flux towards the building of β-glucan chains. We found that overexpression of Pgm2 (phosphoglucomutase) and Rho1 (a GTPase for activating glucan synthesis) significantly increased β-glucan accumulation. After further optimization of culture conditions, the β-glucan content was increased by 53.1%. This study provides a new approach to enhance β-glucan biosynthesis in Saccharomyces cerevisiae.
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Gangqiang He,Guanghua Huo,Liming Liu,Yang Zhu,Jian Chen,Guocheng Du 한국생물공학회 2009 Biotechnology and Bioprocess Engineering Vol.14 No.1
In this study, cutinase production by Thermobifida fusca WSH03-11 was investigated with mixed short-chain organic acids as co-carbon sources to demonstrate the possibility of producing high value-added products from organic wastes. T. fusca WSH03-11 was cultured with different combinations of butyrate, acetate, and lactate with a purpose of increasing cutinase activity. The optimum proportion of butyrate, acetate, and lactate was 4:1:3. In batch cultivation, acetate and lactate were consumed quickly, while the consumption of butyrate was depressed in the presence of acetate with a concentration higher than 0.5 g/L. Based on these results, a two-stage batch and fed-batch cultivation strategy was proposed: a batch culture with acetate and lactate as the co-carbon sources in the first 10 h, and then a fed-batch culture with a constant butyrate feeding rate of 12 mL/h during 11~20 h. By this two-stage cultivation strategy, cutinase activity, dry cell weight, and con-sumption rate of butyrate were increased by 70%, 103.4%, and 4.3-fold, respectively, compared to those of the batch cultivation. These results provided a novel and efficient way to produce high value-added products from organic wastes.
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Huaili Zheng,Tiroyaone Tshukudu,Xuebin Hua,Jun Yang,Mingzhuo Tan,Jiangya Ma,Yongjun Sun,Guocheng Zhu 한국화학공학회 2013 Korean Journal of Chemical Engineering Vol.30 No.3
Response surface method and experimental design were applied as alternatives to the conventional methods for optimization of the coagulation test. A central composite design was used to build models for predicting and optimizing the coagulation process. The model equations were derived using the least square method of the Minitab 16 software. In these equations, the removal efficiency of turbidity and COD were expressed as second-order functions of the coagulant dosage and coagulation pH. By applying RSM, the optimum condition using PFPD1 was coagulant dosage of 384 mg/L and coagulation pH of 7.75. The optimum condition using PFPD2 was coagulant dosage of 390 mg/L and coagulation pH of 7.48. Confirmation experiment demonstrated a good agreement between experimental values and model predicted. This demonstrates that RSM and CCD can be successfully applied for modeling and optimizing the coagulation process using PFPD1 and PFPD2.
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