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      • KCI등재

        Signal Optimization and Coordination for Bus Progression Based on MAXBAND

        Guangyuan Dai,Hao Wang,Wei Wang 대한토목학회 2016 KSCE JOURNAL OF CIVIL ENGINEERING Vol.20 No.2

        A new bandwidth-based approach for bus lane systems is proposed to optimize and coordinate signals and achieve bus progression along urban streets. Elements of the bus systems, such as bus speed, locations of bus stops, and dwell time, were considered to be relevant variables in the proposed approach, which is based on the classic MAXBAND program. First, to establish the bus progression model, intersections along the main street are categorized based on the locations of the bus stops. Second, mixed integer linear programming is employed to construct models that adhere to the following two basic principles: (a) optimizing the bandwidth for each group of intersections and (b) connecting the central lines of green bands for adjacent groups. A software package is then utilized to obtain the global optimal solutions for the model, and a time-space diagram can be created based on the results. Finally, a case study is presented to illustrate the application of the proposed approach. The results show that the proposed approach generates significant improvements in not only the operational performance of the bus lane system but also the average performances of all passengers in the entire traffic system.

      • KCI등재

        Experimental observation of oil mist penetration ability in minimum quantity lubrication (MQL) spray

        Guangyuan Zhu,Songmei Yuan,Xiaoyao Kong,Chong Zhang,Bochuan Chen 대한기계학회 2020 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.34 No.8

        Minimum quantity lubrication (MQL) is an eco-friendly cooling and lubricating method that has its importance in machining sustainability. However, the behavior of the MQL droplets remains questionable. The present study is conducted to investigate the penetration performance of MQL with different combination of spray parameters and capillary sizes. An observation platform has been designed, which makes the overall penetration process controllable. The results have shown that the shortest penetration time was obtained with larger capillary size, higher air flow rate and the corresponding smaller droplet size. However, the increase of air flow rate has the optimal value when the objective is to penetrate to 1 mm deep from the entrance, whereas it has not shown the similar regulation when the droplet flowed deeper to the center due to the long transport distance has amplified the effects of multiple influence factors. The observation results were verified through simulation and cutting experiment.

      • Spectral Color Reproduction from CIE Tristimulus Values Using a Node Address Array Selection Technique

        Guangyuan Wu,Zhen Liu,Jianqing Zhang 보안공학연구지원센터 2015 International Journal of Signal Processing, Image Vol.8 No.9

        This study proposes a feasible method for spectral color reproduction based on a node address array selection technique from CIE tristimulus values. In this method three-dimensional lookup table (3-D LUT) has been constructed to connect the node address array and the spectrum as the source and destination spaces. First we present a general framework for how to reproduce spectral color. Then results of recovery are evaluated by the root mean square error (RMSE) and the color difference CIE ΔE00. According to the results considered, the proposed method could reconstruct the spectral reflectance with a high spectral and colorimetric accuracy.

      • Interconnected hollow carbon nanospheres for stable lithium metal anodes

        Zheng, Guangyuan,Lee, Seok Woo,Liang, Zheng,Lee, Hyun-Wook,Yan, Kai,Yao, Hongbin,Wang, Haotian,Li, Weiyang,Chu, Steven,Cui, Yi Nature Publishing Group, a division of Macmillan P 2014 Nature nanotechnology Vol.9 No.8

        For future applications in portable electronics, electric vehicles and grid storage, batteries with higher energy storage density than existing lithium ion batteries need to be developed. Recent efforts in this direction have focused on high-capacity electrode materials such as lithium metal, silicon and tin as anodes, and sulphur and oxygen as cathodes. Lithium metal would be the optimal choice as an anode material, because it has the highest specific capacity (3,860 mAh g<SUP>–1</SUP>) and the lowest anode potential of all. However, the lithium anode forms dendritic and mossy metal deposits, leading to serious safety concerns and low Coulombic efficiency during charge/discharge cycles. Although advanced characterization techniques have helped shed light on the lithium growth process, effective strategies to improve lithium metal anode cycling remain elusive. Here, we show that coating the lithium metal anode with a monolayer of interconnected amorphous hollow carbon nanospheres helps isolate the lithium metal depositions and facilitates the formation of a stable solid electrolyte interphase. We show that lithium dendrites do not form up to a practical current density of 1 mA cm<SUP>–2</SUP>. The Coulombic efficiency improves to ∼99% for more than 150 cycles. This is significantly better than the bare unmodified samples, which usually show rapid Coulombic efficiency decay in fewer than 100 cycles. Our results indicate that nanoscale interfacial engineering could be a promising strategy to tackle the intrinsic problems of lithium metal anodes.

      • The Impact of Cultural Differences on Financial Quality in Cross-border Mergers and Acquisitions: A Case Study of SAIC Motor and Ssangyong Motor

        Jin, Zheng,Ren, Yanyan,Li, Guangyuan 한중경제문화학회 2016 한중경제문화연구 Vol.6 No.-

        This study discusses several issues which are very important in worldwide mergers and acquisitions, such as cultural differences, culture clashes, operating results and financial quality. A case of SAIC Motor's acquisition of Ssangyong Motor is examined. For this study, 20 financial ratios are used to calculate the financial quality of SAIC in the post-acquisition integration. The result shows that cultural differences possibly have a negative effect on post-acquisition integration and cultural clashes are the root cause of the financial quality plummet. The suggestions are also provided that top managers should pay much more attention to the negative effects of cultural clashes and strengthen cultural integration.

      • KCI등재

        Insights into high molecular weight poly(ethylene 2,5-furandicarboxylate) with satisfactory appearance: Roles of in-situ catalysis of metal zinc

        Xiaoling Qu,Guangyuan Zhou,Rui Wang,Haiyan Zhang,Zhipeng Wang,Min Jiang,Jun Tang 한국공업화학회 2021 Journal of Industrial and Engineering Chemistry Vol.99 No.-

        In pursuit of poly(ethylene 2,5-furandicarboxylate) PEF materials with high molecular weight,satisfactory appearance and faster crystallization rate, its preparation from dimethyl furan-2,5-dicarboxylate (DMFD) with ethylene glycol (EG) in the trace presence of metal zinc was performed viatransesterification method. Optimization of the main polymerization parameters enabled Zn-catalyzedPEF to gain high molecular weight (Mn, 5.40 104 g mol 1) and low content of diethylene glycolfurandicarboxylate unit (DEGF, 2.91%). On the basis of experimental phenomena and high performanceliquid chromatography (HPLC), the actual catalytic active species of metal zinc in the polymerization wasspeculated to be a salt of 2, 5-furandicarboxylate derivative (Zn(II)). The in-stiu catalyst can efficaciouslyinhibit the influence of by-product FDCA on the color of PEF, which displayed quite better appearance(close to white). Differential Scanning Calorimetry (DSC) showed that the in-stiu catalytic system acted asnucleating agent (NA) and the crystallization half-time (t1/2) of PEFs-Zn was only 1/4 of that of PEF-tin. Additionally, series of high molecular weight furan-based polyesters from DMFD and diols with differentmethylene (3, 5, 6 and 8) were obtained by zinc powder as in-stiu catalyst, which further evidenced it tobe efficiency and universality.

      • SCISCIESCOPUS

        Formation of Stable Phosphorus–Carbon Bond for Enhanced Performance in Black Phosphorus Nanoparticle–Graphite Composite Battery Anodes

        Sun, Jie,Zheng, Guangyuan,Lee, Hyun-Wook,Liu, Nian,Wang, Haotian,Yao, Hongbin,Yang, Wensheng,Cui, Yi American Chemical Society 2014 NANO LETTERS Vol.14 No.8

        <P>High specific capacity battery electrode materials have attracted great research attention. Phosphorus as a low-cost abundant material has a high theoretical specific capacity of 2596 mAh/g with most of its capacity at the discharge potential range of 0.4–1.2 V, suitable as anodes. Although numerous research progress have shown other high capacity anodes such as Si, Ge, Sn, and SnO<SUB>2</SUB>, there are only a few studies on phosphorus anodes despite its high theoretical capacity. Successful applications of phosphorus anodes have been impeded by rapid capacity fading, mainly caused by large volume change (around 300%) upon lithiation and thus loss of electrical contact. Using the conducting allotrope of phosphorus, “black phosphorus” as starting materials, here we fabricated composites of black phosphorus nanoparticle-graphite by mechanochemical reaction in a high energy mechanical milling process. This process produces phosphorus–carbon bonds, which are stable during lithium insertion/extraction, maintaining excellent electrical connection between phosphorus and carbon. We demonstrated high initial discharge capacity of 2786 mAh·g<SUP>–1</SUP> at 0.2 C and an excellent cycle life of 100 cycles with 80% capacity retention. High specific discharge capacities are maintained at fast C rates (2270, 1750, 1500, and 1240 mAh·g<SUP>–1</SUP> at C/5, 1, 2, and 4.5 C, respectively).</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/nalefd/2014/nalefd.2014.14.issue-8/nl501617j/production/images/medium/nl-2014-01617j_0006.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/nl501617j'>ACS Electronic Supporting Info</A></P>

      • Low dose Emodin induces tumor senescence for boosting breast cancer chemotherapy via silencing NRARP

        Zu, Cong,Qin, Guangyuan,Yang, Chunshu,Liu, Ning,He, Anning,Zhang, Mingdi,Zheng, Xinyu Elsevier 2018 Biochemical and biophysical research communication Vol.505 No.4

        <P><B>Abstract</B></P> <P><B>Purpose</B></P> <P>The resistance to 5-FU often limits its clinical effectiveness on breast cancer treatment. Combination therapy thus is employed to overcome this treatment resistance. We here report a potent antitumor effect of Emodin at low dose on chemotherapy sensitivity of MCF-7 breast cancer cells.</P> <P><B>Methods</B></P> <P>Cell viability, apoptosis, glutathiones (GSH) concentration and Reactive oxygen species (ROS) activity following Emodin and 5-FU treatment was assessed. Cellular senescence following combined treatment and silence of NRARP was examined by senescence-associated β-galactosidase analysis. Western blot analysis was used to determine changes in the expression of p21, p16, p27, E2F1 and NRARP.</P> <P><B>Results</B></P> <P>Low dose Emodin potentiates 5-FU-induced apoptosis of breast cancer cells, in association with inhibition of NRARP, resulting in cellular senescence. RNA interference of NRARP induced cellular senescence in MCF-7 breast cancer cells. Furthermore, the cellular senescence induced by Emodin and 5-FU treatment could be reverted by pcDNA–NRARP.</P> <P><B>Conclusion</B></P> <P>These findings provide preclinical evidence for repurposing use of Emodin in combination with chemotherapeutic agents to treat breast cancer as an alternative salvage regimen.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The chemoresistance often limits clinical effectiveness of chemotherapy on breast cancer treatment. </LI> <LI> Emodin potentiates 5-FU-induced apoptosis of breast cancer cells. </LI> <LI> Low dose Emodin induces cellular senescence in breast cancer cells by inhibition of Nrarp. </LI> </UL> </P>

      • KCI등재

        CXCL12/CXCR4 Axis is Involved in the Recruitment of NK Cells by HMGB1 Contributing to Persistent Airway Inflammation and AHR During the Late Stage of RSV Infection

        Chen Sisi,Tang Wei,Yu Guangyuan,Tang Zhengzhen,Liu Enmei 한국미생물학회 2023 The journal of microbiology Vol.61 No.4

        We previously showed that both high-mobility group box-1 (HMGB1) and natural killer (NK) cells contribute to respiratory syncytial virus (RSV)-induced persistent airway inflammation and airway hyperresponsiveness (AHR). Meanwhile, Chemokine (C-X-C motif) ligand 12 (CXCL12) and its specific receptor (chemokine receptor 4, CXCR4) play important roles in recruitment of immune cells. CXCL12 has been reported to form a complex with HMGB1 that binds to CXCR4 and increases inflammatory cell migration. The relationship between HMGB1, NK cells and chemokines in RSV-infected model remains unclear. An anti-HMGB1 neutralizing antibody and inhibitor of CXCR4 (AMD3100) was administered to observe changes of NK cells and airway disorders in nude mice and BALB/c mice. Results showed that the mRNA expression and protein levels of HMGB1 were elevated in late stage of RSV infection and persistent airway inflammation and AHR were diminished after administration of anti-HMGB1 antibodies, with an associated significant decrease in CXCR4+ NK cells. In addition, CXCL12 and CXCR4 were reduced after HMGB1 blockade. Treatment with AMD3100 significantly suppressed the recruitment of NK cells and alleviated the airway disorders. Thus, CXCL12/CXCR4 axis is involved in the recruitment of NK cells by HMGB1, contributing to persistent airway inflammation and AHR during the late stage of RSV infection.

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