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Energy-Efficient Algorithm for Assigning Verification Tasks in Cloud Storage
( Guangwei Xu ),( Zhifeng Sun ),( Cairong Yan ),( Xiujin Shi ),( Yue Li ) 한국인터넷정보학회 2017 KSII Transactions on Internet and Information Syst Vol.11 No.1
Mobile Cloud Computing has become a promising computing platform. It moves users` data to the centralized large data centers for users` mobile devices to conveniently access. Since the data storage service may not be fully trusted, many public verification algorithms are proposed to check the data integrity. However, these algorithms hardly consider the huge computational burden for the verifiers with resource-constrained mobile devices to execute the verification tasks. We propose an energy-efficient algorithm for assigning verification tasks (EEAVT) to optimize the energy consumption and assign the verification tasks by elastic and customizable ways. The algorithm prioritizes verification tasks according to the expected finish time of the verification, and assigns the number of checked blocks referring to devices` residual energy and available operation time. Theoretical analysis and experiment evaluation show that our algorithm not only shortens the verification finish time, but also decreases energy consumption, thus improving the efficiency and reliability of the verification.
Sun Chuang,Li Wei,Li Yanhong,Chen Jian,An Huixian,Zeng Guangwei,Wang Tingting,Guo Yazhou,Wang Changying 대한면역학회 2022 Immune Network Vol.22 No.6
Exosomes derived from mesenchymal stem cells (MSCs) could protect against myocardial infarction (MI). TLR4 is reported to play an important role in MI, while microRNA-182-5p (miR-182-5p) negatively regulates TLR4 expression. Therefore, we hypothesize that MSCs-derived exosomes overexpressing miR-182-5p may have beneficial effects on MI. We generated bone marrow mesenchymal stem cells (BM-MSCs) and overexpressed miR-182-5p in these cells for exosome isolation. H2O2-stimulated neonatal mouse ventricle myocytes (NMVMs) and MI mouse model were employed, which were subjected to exosome treatment. The expression of inflammatory factors, heart function, and TLR4 signaling pathway activation were monitored. It was found that miR-182-5p decreased TLR4 expression in BM-MSCs and NMVMs. Administration of exosomes overexpressing miR-182-5p to H2O2-stimulated NMVMs enhanced cell viability and suppressed the expression of inflammatory cytokines. In addition, they promoted heart function, suppressed inflammatory responses, and de-activated TLR4/NF-κB signaling pathway in MI mice. In conclusion, miR-182-5p transferred by the exosomes derived from BM-MSCs protected against MI-induced impairments by targeting TLR4.
Two new meroterpenoids produced by the endophytic fungus Penicillium sp. SXH-65
Xinhua Sun,Xianglan Kong,Huquan Gao,Tianjiao Zhu,Guangwei Wu,Qianqun Gu,Dehai Li 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.8
Two new meroterpenoids, arisugacins I (1) andJ (2), together with five known meroterpenoids includingarisugacin B (3), arisugacin F (4), arisugacin G (5), territremB (6) and territrem C (7) were isolated from anendophytic fungus Penicillium sp. SXH-65. Their structureswere determined by extensive spectroscopic experimentsand comparison with literature data. Theircytotoxicities were evaluated against Hela, HL-60 andK562 cell lines, and only 3 and 4 exhibited weak cytotoxicitiesagainst Hela, HL-60 and K562 cell lines withIC50 values ranging from 24 to 60 lM.
Bao, Chen,Sun, Yongduo,Wu, Yuanjun,Wang, Kaiqing,Wang, Li,He, Guangwei Korean Nuclear Society 2021 Nuclear Engineering and Technology Vol.53 No.6
By using miniature SENB specimens, the fracture properties of the materials in the region of welded metal, 321 stainless steel heat affected zone, 690 alloy heat affected zone of 321/690 dissimilar metal girth welded joints were tested. Both the J-resistance curves and critical fracture toughness of the three different materials are affected by the crack size because of the effect of crack tip constraint. Groups of constraint corrected J-resistance curves of the three materials are obtained according to J-Q-M approach. The welded metals exhibit the best fracture resistance but the worst fracture resistance is observed in the material of 690 alloy heat affected zone.
Injectable In situ Forming Chitosan-Based Hydrogels For Curcumin Delivery
Titima Songkroh,Xiaojun Ma,Hongguo Xie,Weiting Yu,Xiudong Liu,Guangwei Sun,Xiaoxi Xu 한국고분자학회 2015 Macromolecular Research Vol.23 No.1
In this paper, a series of injectable in situ forming chitosan-based hydrogels were prepared by chemicalcrosslinking of chitosan and genipin with the cooperation of ionic bonds between chitosan and sodium salts at roomtemperature. Four hydrogels (A, B, C, and D) were obtained by mixing chitosan, genipin and a sodium salt of trisodiumphosphate (Na3PO4·12H2O), sodium sulfate (Na2SO4), sodium sulfite (Na2SO3), or sodium bicarbonate (NaHCO3)and examined for their characteristics, morphology, and rheological properties. Their cell viability assaysexhibited low toxicity and the localized in situ gel formation was detected after subcutaneous injections in rat. Curcuminwhich possesses many pharmaceutical potentials but has low bioavailability, was chosen as a drug model. Invitro curcumin release profiles exhibit sustained release properties with initial burst release for all hydrogels withabout 3 to 6 times higher cumulative release than other gel controls. The results of this study demonstrate that ourhydrogels have a potential as local curcumin carriers.