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      • KCI등재

        Perception of Discipline According to Gender, Type of School, Sport Activity and Interest in Physical Education in Spanish Students

        ( Juan Antonio Moreno Murcia ),( Eduardo Cervello Gimeno ),( Celestina Martinez Galindo ) 한국스포츠정책과학원(구 한국스포츠개발원) 2007 International Journal of Applied Sports Sciences Vol.19 No.2

        The purpose of this study was to compare the differences between different groups (student`s gender, type of school, interest in physical education (PE) and sport activity outside school hours), based on the student`s disciplined/undisciplined behaviour in the PE class. The sample was formed by 456 students aged between 14 and 16, from the 3rd and 4th ESO (compulsory secondary education) course in the Region of Murcia (Spain). The study was performed in the months of the third school term and the questionnaire was handed out in the PE hall. The scales used for the study were the Reasons for Discipline Scale (RDS) and Strategies to Sustain Discipline Scale (SSDS), both created by Papaioannou (1998). The results obtained from the univariate analyses showed that girls were more disciplined and perceived more intrinsic reasons in their teachers for maintaining discipline than boys, who demonstrated more undisciplined behaviour and perceived more reasons of indifference or introjection in their teachers for maintaining discipline. On the other hand, students that liked PE and did sport were more disciplined and perceived more intrinsic reasons in their teachers for maintaining discipline.

      • KCI등재

        Metformin treatment reduces motor and neuropsychiatric phenotypes in the zQ175 mouse model of Huntington disease

        Ana Sanchis,María Adelaida García-Gimeno,Antonio José Cañada-Martínez,María Dolores Sequedo,José María Millán,Pascual Sanz,Rafael P. Vázquez-Manrique 생화학분자생물학회 2019 Experimental and molecular medicine Vol.51 No.-

        Huntington disease is a neurodegenerative condition for which there is no cure to date. Activation of AMP-activated protein kinase has previously been shown to be beneficial in in vitro and in vivo models of Huntington’s disease. Moreover, a recent cross-sectional study demonstrated that treatment with metformin, a well-known activator of this enzyme, is associated with better cognitive scores in patients with this disease. We performed a preclinical study using metformin to treat phenotypes of the zQ175 mouse model of Huntington disease. We evaluated behavior (motor and neuropsychiatric function) and molecular phenotypes (aggregation of mutant huntingtin, levels of brain-derived neurotrophic factor, neuronal inflammation, etc.). We also used two models of polyglutamine toxicity in Caenorhabditis elegans to further explore potential mechanisms of metformin action. Our results provide strong evidence that metformin alleviates motor and neuropsychiatric phenotypes in zQ175 mice. Moreover, metformin intake reduces the number of nuclear aggregates of mutant huntingtin in the striatum. The expression of brain-derived neurotrophic factor, which is reduced in mutant animals, is partially restored in metformin-treated mice, and glial activation in mutant mice is reduced in metformin-treated animals. In addition, using worm models of polyglutamine toxicity, we demonstrate that metformin reduces polyglutamine aggregates and restores neuronal function through mechanisms involving AMP-activated protein kinase and lysosomal function. Our data indicate that metformin alleviates the progression of the disease and further supports AMP-activated protein kinase as a druggable target against Huntington’s disease.

      • SCIESCOPUSKCI등재

        Determination of Diesel Sprays Characteristics in Real Engine In - Cylinder air Density and Pressure Conditions

        Raul Payri,F. J. Salvador,J. Gimeno,V. Soare 대한기계학회 2005 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.19 No.11

        The present paper centers on the establishment of a quantified relationship between the macroscopic visual parameters of a Diesel spray and its most influential factors. The factors considered are the ambient gas density, as an external condition relative to the injection system, and nozzle hole diameter and injection pressure as internal ones. The main purpose of this work is to validate and extend the different correlations available in the literature to the present state of the Diesel engine, i.e. high injection pressure, small nozzle holes, severe cavitating conditions, etc. Five mono-orifice, axi-symmetrical nozzles with different diameters have been studied in two different test rigs from which one can reproduce solely the real engine in-cylinder air density, and the other, both the density and the pressure. A parametric study was carried out and it enabled the spray tip penetration to be expressed as a function of nozzle hole diameter, injection pressure and environment gas density. The temporal synchronization of the penetration and injection rate data revealed a possible explanation for the discontinuity observed as well by other authors in the spray’s penetration law. The experimental results obtained from both test rigs have shown good agreement with the theoretical analysis. There have been observed small but consistent differences between the two test rigs regarding the spray penetration and cone angle, and thus an analysis of the possible causes for these differences has also been included.

      • SCIESCOPUSKCI등재

        A Study of the Relation Between Nozzle Geometry, Internal flow and Sprays Characteristics in Diesel Fuel Injection Systems

        Payri, Raul,Molina, S.,Salvador, F.J.,Gimeno, J. The Korean Society of Mechanical Engineers 2004 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.18 No.7

        This study examines the influence of geometry on the internal flow and macroscopic behavior of the spray in Diesel nozzles. For this investigation, two bi-orifice nozzles were employed: one cylindrical and one conical. The first step is to use a non-destructive characterization method which is based on the production of silicone moulds so that the precise internal geometry of the two nozzles can be measured. At this stage the nozzles have been characterized dimensionally and therefore the internal flow can be studied using CFD calculations. The results gained from this experiment make it possible also to ascertain the critical cavitation conditions. Once the critical cavitation conditions have been identified, the macroscopic parameters of the spray can be studied in both cavitating and non-cavitating conditions using a test rig pressurized with nitrogen and with the help of a image acquisition system and image processing software. Consequently, research can be carried out to determine the influence that cavitation has on macroscopic spray behavior. From the point of view of the spray macroscopic behavior, the main conclusion of the paper is that cavitation leads to an increment of the spray cone angle. On the other hand, from the point of view of the internal flow, the hole outlet velocity increases when cavitation appears. This phenomenon can be explained by the reduction in the cross section of the liquid phase in the outlet section of the hole.

      • KCI등재

        Analyzing Nursing Leadership at an Academic Historical Event: A Descriptive Study Based On Social Networks

        Marqués-Sánchez Pilar,Cummings Greta,Martínez-Fernández María Cristina,Martínez-Gimeno María Lara,López María,Serrano-Fuentes Néstor 한국간호과학회 2020 Asian Nursing Research Vol.14 No.2

        Purpose: To analyze the leadership network structure among nursing leaders in Spain identified through the Grupo40Enfermeras y Universidad event. Methods: A descriptive cross-sectional study using social network analysis was used. Study sample consisted of 210 individuals, of whom 119 received nominations as referents. Structural analysis of the network was conducted using centrality and cohesion. Results: A network structure was generated in which different leadership strategies were identified through InDegree, Eigenvector, and Betweenness Centrality. Five leaders were identified as bridges to other individuals using Betweenness. The whole network presented little cohesion although two highly cohesive cores were detected by K-core measurements. Conclusion: A strategy is needed to support nursing leaders with high degree of Betweenness to serve as bridges to connect other nursing leaders

      • KCI등재

        A Study of the Relation Between Nozzle Geometry, Internal flow and Sprays Characteristics in Diesel Fuel Injection Systems

        Raul Payri,S. Molina,F. J. Salvador,J. Gimeno 대한기계학회 2004 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.18 No.7

        This study examines the influence of geometry on the internal flow and macroscopic behavior of the spray in Diesel nozzles. For this investigation, two bi-orifice nozzles were employed: one cylindrical and one conical. The first step is to use a non-destructive characterization method which is based on the production of silicone moulds so that the precise internal geometry of the two nozzles can be measured. At this stage the nozzles have been characterized dimensionally and therefore the internal flow can be studied using CFD calculations. The results gained from this experiment make it possible also to ascertain the critical cavitation conditions. Once the critical cavitation conditions have been identified, the macroscopic parameters of the spray can be studied in both cavitating and non-cavitating conditions using a test rig pressurized with nitrogen and with the help of a image acquisition system and image processing software. Consequently, research can be carried out to determine the influence that cavitation has on macroscopic spray behavior. From the point of view of the spray macroscopic behavior, the main conclusion of the paper is that cavitation leads to an increment of the 'spray cone angle. On the other hand, from the point of view of the internal flow, the hole outlet velocity increases when cavitation appears. This phenomenon can be explained by the reduction in the cross section of the liquid phase in the outlet section of the hole.

      • KCI등재

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