편위각이 큰 외사시에서 양안 외직근 후전술의 수술 결과

신동빈 ( Dong Bin Shin ),송영진 ( Young Jin Song ),이성복 ( Seong Bok Lee ),허영근 ( Young Gen Xu ),민병무 ( Byung Moo Min ) 대한안과학회 2003 대한안과학회지 Vol.44 No.6

잔여내사시에서 양안 외직근 절제술의 수술 성적

신동빈 ( Dong Bin Shin ),이연희 ( Yeon Hee Lee ),이성복 ( Seong Bok Lee ),허영근 ( Young Gen Xu ),민병무 ( Byung Moo Min ) 대한안과학회 2003 대한안과학회지 Vol.44 No.5

Imaging Anatomy of Waldeyer's Ring and PET/CT and MRI Findings of Oropharyngeal Non-Hodgkin's Lymphoma

Zhang, Chun-Xing,Liang, Long,Zhang, Bin,Chen, Wen-Bo,Liu, Hong-Jun,Liu, Chun-Ling,Zhou, Zheng-Gen,Liang, Chang-Hong,Zhang, Shui-Xing Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.8

Background: This study was conducted to analyze positron emission tomography (PET) / computed tomography (CT) and magnetic resonance imaging (MRI) performance with oropharyngeal non-Hodgkin's lymphoma (ONHL).Materials and Methods: The complete image data of 30 ONHL cases were analyzed, all patients were performed PET / CT and MRI examination before the treatment, with the time interval of these two inspections not exceeding 14 days. The distribution, morphology, MRI signal characteristics, enhancement feature, standardized uptake value (SUV) max value and lymph node metastasis way of the lesions were analyzed. Results: Among the 30 cases, 23 cases were derived from the B-cell (76.7%), 5 cases were derived from the peripheral T cells (16.7%) and 2 cases were derived from the NK/T cells (6.7%). 19 cases exhibited the palatine tonsil involvement (63.3%). As for the lesion appearance, 10 cases appeared as mass, 8 cases were the diffused type and 12 cases were the mixed type. 25 cases exhibited the SUVmax value of PET / CT primary lesions as 11 or more (83.3%). MRI showed that all patients exhibited various degrees of parapharyngeal side-compressed narrowing, but MRI still exhibited the high-signal fat, and the oropharyngeal mucosa was intact. 25 cases were associated with the neck lymph node metastasis, among who 22 cases had no necrosis in the metastatic lymph nodes, while the rest 3 cases exhibited the central necrosis in the metastatic lymph nodes. Conclusions: PET / CT and MRI have important value in diagnosing and determining the lesion extent of ONHL.

저수지 제방 보수보강을 위한 하이브리드형 그라우트재 연구

박성용(Sung-Yong Park),심홍근(Houng-Gen Shim),강희진(Hee-Jin Kang),임원빈(One-Bin Lim),사미 플림반(Ghazali-Flimban Sami),김용성(Yong-Seong Kim) 한국지반신소재학회 2017 한국지반신소재학회 논문집 Vol.16 No.3

노후저수지 제체 보강을 목적으로 시멘트 그라우팅공법이 일반적으로 적용되고 있으나, 주입재의 재료적 한계로 인해 여러 문제점이 제기되어 왔다. 이를 극복하기 위하여 국내에서도 다양한 그라우트 재료들을 개발하고 현장에 적용하고 있으나 실제 현장에서 침투주입시 원지반 교란으로 인한 문제가 야기되는 경우가 많다. 본 연구에서는 이와 같은 문제점을 개선하기 위하여 원지반에의 이상적인 침투주입이 가능하도록 고분말, 고점도의 특성을 가지며 실트질 모래층까지 침투주입을 확장시키고 복합조건의 지반에서도 적용할 수 있는 하이브리드형 그라우트재의 물리적 특성을 분석하였으며, 최적의 팽창제를 선정하여 그라우트재와 혼합한 후 부피팽창에 따른 압력과 다짐효과를 검토하여 실효성을 검증하고자 하였다. 팽창율, 일축압축강도, 팽창압력 및 다짐효과확인시험 결과, HI-E(2%) 시료는 팽창제에 의한 개선효과가 탁월한 것으로 나타나 이를 혼합한 하이브리드형 그라우트재는 노후저수지, 방조제 등의 차수 및 보강공법에 효과적으로 적용이 가능할 것으로 판단된다. Cement grouting method is generally applied for the purpose of reinforcement of deteriorated reservior. Problems have been raised due to the limit of the injection material. In order to solve these problems, various grout materials have been developed. However, there are many cases in which the grounds are disturbed in actual field. In this study, the physical properties of hybrid grout with high fineness and high viscosity characteristics were analyzed to enable penetration into the ground. Optimum inflation agent was selected and mixed with the grout. The pressure and compaction effect on expansion was examined and its effectiveness was verified. From the result of confirming expansion ratio, uniaxial compressive strength, expansion pressure and compaction effect, the HI-E (2%) sample was analyzed to be excellent in improvement effect by the inflation agent. Hence, hybrid grout can be effectively applied for the impermeable and reinforcement method of deterioration reservoir and tide embankment.

Cordblood-Based High-Throughput Screening for Deafness Gene of 646 Newborns in Jinan Area of China

Shou-Xia Li,Ding-Li Chen,Su-Bin Zhao,Li-Li Guo,Hai-Qin Feng,Xiao-Fang Zhang,Li-Li Ping,Zhi-Ming Yang,Cai-Xia Sun,Gen-Dong Yao 대한이비인후과학회 2015 Clinical and Experimental Otorhinolaryngology Vol.8 No.3

Objectives. Infants with slight/mild or late-onset hearing impairment might be missed in universal newborn hearing screening (UNHS). We identified the mutation hot spot of common deaf gene in the newborns in Jinan area population by screening the mutation spot with neonate cord blood, in order to make clear whether the neonate cord blood for screening is feasible. Methods. Six hundred and forty-six newborns were subjected to both UNHS and genetic screening for deafness by using neonate cord blood. The newborn genetic screening targeted four deafness-associated genes, which were commonly found in the Chinese population including gap junction beta-2 protein (GJB2), gap junction beta-3 protein (GJB3), solute carrier family 26 member 4 (SLC26A4), and mtDNA 12S rRNA. The most common 20 spot mutations in 4 deaf genes were detected by MassARRAY iPLEX platform and mitochondrial 12S rRNA A1555G and C1494T mutations were sequenced using Sanger sequencing. Results. Among the 646 newborns, 635 cases passed the UNHS and the other 11 cases (1.7%) did not. Of the 11 failures, two cases were found to carry homozygous GJB2 p.R143W pathogenic mutation, one case was found to have heterozygous GJB2 235delC mutation, and another one case carried heterozygous GJB3 p.R180X pathogenic mutation. Six hundred and thirty-five babies passed the newborn hearing screening, in which 25 babies were identified to carry pathogenic mutations, including 12 heterozygotes (1.9%) for GJB2 235delC, eight heterozygotes (1.3%) for SLC26A4 IVS7-2A>G, one heterozygote (0.2%) for p.R409H, two homozygotes (0.3%) for m.1494C>T, and two homozygotes (0.3%) for m.1555A>G. Conclusion. Newborn genetic screening through the umbilical cord blood for common deafness-associated mutations may identify carriers sensitive to aminoglycoside antibiotic, and can effectively prevent or delay hearing loss occurs.

25 PD 이하 간헐외사시에서 단안 외직근 후전술의 효과

이수나 ( Su Na Lee ),신동빈 ( Dong Bin Shin ),허영근 ( Young Gen Xu ),민병무 ( Byung Moo Min ) 대한안과학회 2002 대한안과학회지 Vol.43 No.8

침투다짐형 팩커를 이용한 침투다짐 그라우트의 주입 효과

박성용(Sung-Yong Park),심홍근(Houng-Gen Shim),강희진(Hee-Jin Kang),임원빈(One-Bin Lim),김용성(Yong-Seong Kim) 한국지반신소재학회 2017 한국지반신소재학회 논문집 Vol.16 No.2

저수지 제방의 그라우팅시 가장 이상적인 주입형태는 침투주입이지만 일반적으로 침투와 할렬주입이 복합적으로 시공되어 원지반의 교란이 발생될 가능성이 존재한다. 이와 같은 문제점을 개선하기 위하여 이상적인 침투주입을 가능하게 하는 그라우트 재료를 이용하여 저압주입과 팽창제를 이용한 주입재의 팽창력으로 그라우팅 주입공 주변에 대한 다짐을 실시하고 순차적으로 그라우트재를 주입하는 방법이 유용하다. 본 연구에서는 그라우트 주입공 주변에 대한 침투다짐효과를 얻기 위하여 하이브리드형 주입재와 팽창제를 혼합한 침투다짐 그라우트를 PC(Permeable Compaction)팩커를 이용하여 주입한 그 효과에 대해 고찰하였다, 본 연구결과, PC팩커와 침투다짐 그라우트를 저수지 보수보강 그라우팅 공사에 적용할 경우 저수지 차수 그라우팅의 성능기준에 부합하는 침투다짐효과가 발휘될 수 있음을 확인하였다. Permeating injection is commonly known as an ideal type of injection in grouting reservoir embankment, yet often-combined permeating and fracturing injection grouting operation can disturb the original soil. A grouting method has been regarded as effective and developed to ameliorate the possible disturbance problem. It involves compaction grouting with low expansive pressure near the injection hole and repetitive injection and compaction with grout material that allows ideal permeating injection. This thesis develops Hybrid Grout (ie. HG grout) that allows various application in any ground condition combined together, has high fineness and low viscosity, and expands permeation injection to silty sand. It researches on the injection effect of permeable compaction grout which is done with PC packer and is a combination of HG grout and expansion agent to obtain permeation compaction effect on the area near grout injection spot by developing Permeable Compaction Type Packer(ie. PC packer). As the developed PC packer, HG grout, and and expansion agent (HI-E) are applied to reservoir embankment reinforcement grouting, possibile permeation compaction effect that satisfies reservoir embankment grouting standard is confirmed according to the research.

Modification of Fe/Cu Multilayers under 2-MeV Xe20+ Irradiation

Kong-Fang Wei,Zhi-Guang Wang,Jie Gou,Yan-Bin Sheng,Gen-Ming Jin,Hang Zang,Cun-Feng Yao,Yi-Zhun Ma,Tie-Long Shen 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.55 No.6

Multilayers with a structure of Si/[Fe(10 nm)/Cu(10 nm)]5 were deposited on Si(100) substrates and then irradiated at room temperature by using 2-MeV Xe20+. The modifications of the multilayers were characterized using a depth profile analysis of the Auger electron spectroscopy (AES) data and the evolution of crystallite structures of the multilayers were analyzed by using X-ray diffraction (XRD). The AES depth profiles indicated that de-mixing of the Fe and the Cu layers was observed at low ion fluences, but inter-mixing of the Fe and the Cu layers was found at high ion fluences and destroyed the layered structure of the multilayers. The obtained XRD patterns showed that, after irradiation by 2-MeV Xe20+ at 2 × 1016 ions/cm2, the peaks of the multilayers related to a Cu-based fcc solid solution and an Fe-based bcc solid solution phase became visible, which implied that the inter-mixing at the Fe/Cu interface resulted in the formation of new phases. A possible mechanism of modification in the Fe/Cu multilayers induced by ion irradiation is briefly discussed. Multilayers with a structure of Si/[Fe(10 nm)/Cu(10 nm)]5 were deposited on Si(100) substrates and then irradiated at room temperature by using 2-MeV Xe20+. The modifications of the multilayers were characterized using a depth profile analysis of the Auger electron spectroscopy (AES) data and the evolution of crystallite structures of the multilayers were analyzed by using X-ray diffraction (XRD). The AES depth profiles indicated that de-mixing of the Fe and the Cu layers was observed at low ion fluences, but inter-mixing of the Fe and the Cu layers was found at high ion fluences and destroyed the layered structure of the multilayers. The obtained XRD patterns showed that, after irradiation by 2-MeV Xe20+ at 2 × 1016 ions/cm2, the peaks of the multilayers related to a Cu-based fcc solid solution and an Fe-based bcc solid solution phase became visible, which implied that the inter-mixing at the Fe/Cu interface resulted in the formation of new phases. A possible mechanism of modification in the Fe/Cu multilayers induced by ion irradiation is briefly discussed.

Migraine Susceptibility Genes in Han Chinese of Fujian Province

Qi-fang Lin,Zi-chun Chen,Xian-guo Fu,Jing Yang,Luo-yuan Cao,Long-teng Yao,Yong-tong Xin,Gen-bin Huang 대한신경과학회 2017 Journal of Clinical Neurology Vol.13 No.1

Background and Purpose Five single-nucleotide polymorphisms (SNPs) (rs4379368, rs10504861, rs10915437, rs12134493 and rs13208321) were recently identified in a Western population with migraine. These migraine-associated SNPs have not been evaluated in a Han Chinese population. This study investigated the associations of specific SNPs with migraine in a Han population. Methods This was a case-control study of Han Chinese residing in Fujian Province. Polymerase chain reaction—restriction-fragment-length polymorphism analysis and direct sequencing were used to characterize the relationships of SNPs in a control group of 200 subjects and in a migraine group of 201 patients. Results The frequencies of the five SNPs did not differ between patients with migraine and healthy non migraine controls. However, subgroup analysis indicated certain SNPs were more strongly associated with migraine with aura or migraine without aura than with controls. The CT genotype of rs4379368 was more common in migraine patients with aura (75%) than in migraine patients without aura (47.9%) and controls (48.5%) (p<0.05), and the TT genotype of rs10504861 was more common in migraine patients with aura than in controls (8.3% vs. 0.5%) (p<0.05). Meanwhile, the CC genotype of rs12134493 was less common in migraine patients without aura than in controls (80.6% vs. 88%) (p<0.05). Conclusions Our findings suggest that the rs4379368 and rs10504861 SNPs are markers for susceptibility to migraine with aura and that rs12134493 is a marker for the risk of migraine without aura in this Han population. Future studies should further explore if these associations vary by ethnicity.