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Luis Enrique Garcia-Rios,Ana K. Garcia-Avila,Marisol Luna-Castillo,Jazmin G. De Anda-Gonzalez,Rafael Medrano-Guzman 한국간담췌외과학회 2021 Annals of hepato-biliary-pancreatic surgery Vol.25 No.4
Germ cell tumors (GCTs) are considered as extragonadal if there is no evidence of a primary tumor in the testes or ovaries. GCTs can be classified as seminomas, non-seminomatous, mature teratomas, and immature teratomas based upon histology. Mature teratomas are generally found in prepuberal children. Less than 1% of them have been reported in the gastrointestinal tract and liver. Liver teratomas are extremely rare. There are only 11 cases reported in adults up to 2018. Isolated liver metastasis of ovarian teratoma is also very rare. We present a case of a late metachronous recurrence of liver cystic teratoma with gliosis peritonei in a female adult treated by a right extended hepatectomy along with a literature review.
Sandra Castillo,Jorge Dávila-Aviña,Norma Heredia,Santos Garcia 한국식품과학회 2017 Food Science and Biotechnology Vol.26 No.2
Adherence and invasion to cells are the key processes during infection development by Campylobacter jejuni (C. jejuni). In this study, extracts from the byproducts of Citrus limon, Citrus aurantium, and Citrus medica were added to the cultures of C. jejuni, and the adherence and invasion of C. jejuni to HeLa cells and the expression of cadF and ciaB genes were analyzed. The relative expression of the genes was determined by quantitative reverse transcription PCR (qRT-PCR). The antioxidant activity was determined using spectrophotometric methods. Byproduct extracts at subinhibitory concentrations affected the adherence (reduced 2.3 to 99%) and invasion (reduced 71.3 to 99.2%) to the HeLa cells. The expression of cadF and ciaB was reduced from 66 to 99% and from 81 to 99%, respectively. The total phenolic content of the byproducts varied from 92 to 26 mg GAE/g and the total flavonoids varied from 161 to 29.29 mg QE/g. C. aurantium showed the highest percentage of radical scavenging activity (RSA, 90.1). These extracts can prove as effective alternatives for devising new strategies to control Campylobacter infections.
O. Benavente-Garcia,J. Castillo,J. Lorente,M. Alcaraz 한국식품영양과학회 2002 Journal of medicinal food Vol.5 No.3
The radioprotective effects of a polyphenolic extract of Olea europaea L. leaves (OL); theflavonoids diosmin and rutin, which are widely used as pharmaceuticals; and the sulfur-con-taining compounds dimethylsulfoxide (DMSO) and 6-n-propyl-2-thiouracil (PTU) were de-termined by using the micronucleus test for anticlastogenic activity, evaluating the reductionof the frequency of micronucleated polychromatic erythrocytes (MnPCEs) in bone marrow ofmouse before and after X-ray irradiation. With treatment before X-irradiation, the most ef-fective compounds were, in order, rutin . DMSO . OL . PTU. diosmin. These resultsshowed, for the polyphenols studied, a linear correlation (r2 5 0.965) betwen anticlastogenicactivity and antioxidant capacity. The magnitude of protection with treatment after X-irradi-ation were lower, and the most effective compounds were, in order, OL . diosmin . rutin;DMSO and PTU lacked radioprotective activity. Therefore, OL is the only substance thatshowed a significant anticlastogenic activity both before and after X-ray irradiation treatments.Structurally, the fre oxygen radicals and lipoperoxyradicals scavenging capacity and, conse-quently, the anticlastogenic activity of these polyphenolic compounds are based principallyon the presence of specific functional groups, mainly catechol groups (rutin, oleuropein, hy-droxytyrosol, verbascoside, luteolin), that also increase the stability of the aroxyl-polyphenolradical generated in the above processes.125
Assembly strategies of wind turbine towers for minimum fatigue damage
Nunez-Casado, Cristina,Lopez-Garcia, Oscar,de las Heras, Enrique Gomez,Cuerva-Tejero, Alvaro,Gallego-Castillo, Cristobal Techno-Press 2017 Wind and Structures, An International Journal (WAS Vol.25 No.6
The aim of this paper is to present a method to obtain the dynamic response of a wind turbine tower in time domain by means of the generation of time series and to estimate the associated fatigue damage by means of a Rainflow counting algorithm. The proposed method is based on assuming the vortex shedding is a bidimensional phenomena and on following a classical modal superposition method to obtain the structure dynamic response. Four different wind turbine tower geometric configurations have been analyzed in a range of usual wind velocities and covering extreme wind velocities. The obtained results have shown that, depending on the turbulence intensity and the mean wind velocity, there are tower geometric configurations more advantageous from the fatigue load standpoint. Consequently, the presented model can be utilized to define assembly strategies oriented to fatigue damage minimization.
A non-dimensional theoretical approach to model high-velocity impact on thick woven plates
L. Alonso,D. Garcia-Gonzalez,C. Navarro,S.K. García-Castillo 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.38 No.6
A theoretical energy-based model to capture the mechanical response of thick woven composite laminates, which are used in such applications as maritime or aerospace, to high-velocity impact was developed. The dependences of the impact phenomenon on material and geometrical parameters were analysed making use of the Vaschy-Buckingham Theorem to provide a non-dimensional framework. The model was divided in three different stages splitting the physical interpretation of the perforation process: a first where different dissipative mechanisms such as compression or shear plugging were considered, a second where a transference of linear momentum was assumed and a third where only friction took place. The model was validated against experimental data along with a 3D finite element model. The numerical simulations were used to validate some of the new hypotheses assumed in the theoretical model to provide a more accurate explanation of the phenomena taking place during a high-velocity impact.
Kinematic and deformation analyses of a translational parallel robot for drilling tasks
R. Maldonado-Echegoyen,E. Castillo-Castaneda,M. A. Garcia-Murillo 대한기계학회 2015 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.29 No.10
A 3DOF translational parallel robot for drilling tasks based on two 5-bar mechanisms with a large workspace is presented in this study. The position analysis is performed by applying simple geometric procedures, and the velocity and acceleration analyses are developedusing the theory of screws. A numerical example is included in the contribution to validate the equations of the kinematic analysis, anddeformation analysis is performed to assess the accuracy considering the forces reported in the literature for drilling process. A prototypeis presented, and an experimental test is performed to validate accuracy using a circular test.
Assembly strategies of wind turbine towers for minimum fatigue damage
Cristina Nunez-Casado,Oscar Lopez-Garcia,Enrique Gomez de las Heras,Alvaro Cuerva-Tejero,Cristobal Gallego-Castillo 한국풍공학회 2017 Wind and Structures, An International Journal (WAS Vol.25 No.6
The aim of this paper is to present a method to obtain the dynamic response of a wind turbine tower in time domain by means of the generation of time series and to estimate the associated fatigue damage by means of a Rainflow counting algorithm. The proposed method is based on assuming the vortex shedding is a bidimensional phenomena and on following a classical modal superposition method to obtain the structure dynamic response. Four different wind turbine tower geometric configurations have been analyzed in a range of usual wind velocities and covering extreme wind velocities. The obtained results have shown that, depending on the turbulence intensity and the mean wind velocity, there are tower geometric configurations more advantageous from the fatigue load standpoint. Consequently, the presented model can be utilized to define assembly strategies oriented to fatigue damage minimization.
Hernandez-Flores, Mario A.,Galeano-Torres, Rodrigo,Garcia-Castillo, Miguel A.,Landeros-Ayala, Salvador,Matias-Maruri, Jose M. Electronics and Telecommunications Research Instit 2021 ETRI Journal Vol.43 No.4
This work proposes suitable network configurations for single frequency networks (SFNs) with ATSC 1.0 based on network coverage calculations and the laboratory multipath handling performance of commercial receivers. SFNs are widely used for delivering terrestrial digital television services because of their efficient use of the spectrum. In Mexico the analogue television transmissions switch-off occurred on 31 December 2016. Thus it is expected the adopted ATSC 1.0 system will be in force for the next several years despite the recent standardization of the ATSC 3.0 system. As ATSC 1.0 uses 8-VSB modulation the multipath handling capability of receivers is critical for the design of SFNs. The presented network planning results help develop technical normativity for implementing SFNs in Mexico and other countries that use ATSC 1.0. SFNs with transmitter separation up to 130 km are fully covered for outdoor reception mainly due to the directivity of the receiving antenna. Moreover for indoor reception at least 70% of an SFN coverage area can be achieved with a transmitter separation of up to 60 km depending on the radiated power and the transmitter antenna height.
Concept Design and Performance Evaluation of UAV-based Backhaul Link with Antenna Steering
Jiri Pokorny,Aleksandr Ometov,Pablo Pascual,Carlos Baquero,Pavel Masek,Alexander Pyattaev,Ainoa Garcia,Carlos Castillo,Sergey Andreev,Jiri Hosek,Yevgeni Koucheryavy 한국통신학회 2018 Journal of communications and networks Vol.20 No.5
At present, cellular coverage in many rural areas remainsintermittent. Mobile operators may not be willing to deployexpensive network infrastructure to support low-demand regions. For that reason, solutions for the rapid deployment of base stationsin areas with insufficient or damaged operator infrastructureare emerging. Utilization of unmanned aerial vehicles (UAVs) ordrones serving as data relays holds significant promise for deliveringon-demand connectivity as well as providing public safety servicesor aiding in recovery after communication infrastructure failurescaused by natural disasters. The use of UAVs in provisioninghigh-rate radio connectivity and bringing it to remote locations isalso envisioned as a potential application for fifth-generation (5G)communication systems. In this study, we introduce a prototypesolution for an aerial base station, where connectivity between adrone and a base station is provided via a directional microwavelink. Our prototype is equipped with a steering mechanism drivenby a dedicated algorithm to support such connectivity. Our experimentalresults demonstrate early-stage connectivity and signalstrength measurements that were gathered with our prototype. Our results are also compared against the free-space model. Thesefindings support the emerging vision of aerial base stations as partof the 5G ecosystem and beyond.
Guillermo Rubio-Gómez,Sergio Juárez,David Rodríguez-Rosa,Enrique Bravo,Erika Ottaviano,Antonio Gonzalez-Rodriguez,Fernando J. Castillo-Garcia 국제구조공학회 2021 Smart Structures and Systems, An International Jou Vol.27 No.2
Cable-driven robots are parallel manipulators in which rigid links are replaced by actuated cables. The end-effector is then supported by a set of cables commanded by motors that are usually placed in a fixed frame. By varying the cables length, it is possible to change the end-effector position and/or orientation. Among the advantages presented by cable robots are they light-weight structure, high energy efficiency and their ability to cover large workspaces since cables are easy to wind. When high-speed operation is not required, a safer solution is to design cable-driven suspended robots, where all vertical components of cables tension are against gravity direction. Cable-driven suspended robots present limited workspace due to the elevated torque requirements for the higher part of the workspace. In this paper, the addition of a passive carriage in the top of the frame is proposed, allowing to achieve a much greater feasible workspace than the conventional one, i.e., with the same size as the desired inspection area while maintaining the same motor requirements. In the opposite, this new scheme presents non-desired vibration during the end-effector maneuvers. These vibrations can be removed by means of a more complex control strategy. Kinematics and dynamics models are developed in this paper. An analysis of sensor system is carried out and a control scheme is proposed for controlling the end-effector pose. Simulation and experimental results show that the feasible workspace can be notoriously increased while end-effector pose is controlled. This new architecture of cable-driven robot can be easily applied for automated inspection and monitoring of very large vertical surfaces of civil infrastructures, such as facades or dams.