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      • KCI등재

        Efficacy of reciprocating instruments and final irrigant activation protocols on retreatment of mesiobuccal roots of maxillary molars: a micro-CT analysis

        Tietz Lilian,Furlan Renan Diego,da Rosa Ricardo Abreu,Duarte Marco Antonio Hungaro,Alcalde Murilo Priori,Vivan Rodrigo Ricci,Weissheimer Theodoro,Só Marcus Vinicius Reis 대한치과보존학회 2022 Restorative Dentistry & Endodontics Vol.47 No.1

        Objectives This study evaluated the efficacy of 3 reciprocating systems and the effects of 2 instruments for irrigant activation on filling material removal. Materials and Methods Forty mesiobuccal roots of maxillary molars were prepared up to size 25.06 and obturated. Micro-computed tomography (micro-CT) examination #1 was performed. Teeth were then divided into 4 groups (n = 10), according to the retreatment protocol: (1) manual, (2) Reciproc Blue, (3) WaveOne Gold, and (4) X1 Blue. Micro-CT examinations #2 and #3 were performed after filling removal and repreparation, respectively. Next, all teeth were divided into 2 new groups (n = 20) according to the irrigant activation protocol: XP Clean (XP Clean size 25.02) and Flatsonic (Flatsonic ultrasonic tip). Micro-CT examination #4 was performed after irrigant activation. Statistical analysis was performed with a significance level set at 5%. Results WaveOne Gold removed a significantly greater amount of filling material than the manual group (p < 0.05). The time to reach the WL was similar for all reciprocating systems (p > 0.05). X1 Blue was faster than the manual group (p < 0.05). Only manual group improved the filling material removal after the repreparation stage (p < 0.05). Both activation protocols significantly improved the filling material removal (p < 0.05), without differences between them (p > 0.05). Conclusions None of the tested instruments completely removed the filling material. X1 Blue size 25.06 reached the working length in the shortest time. XP Clean and Flatsonic improved the filling material removal. Objectives This study evaluated the efficacy of 3 reciprocating systems and the effects of 2 instruments for irrigant activation on filling material removal. Materials and Methods Forty mesiobuccal roots of maxillary molars were prepared up to size 25.06 and obturated. Micro-computed tomography (micro-CT) examination #1 was performed. Teeth were then divided into 4 groups (n = 10), according to the retreatment protocol: (1) manual, (2) Reciproc Blue, (3) WaveOne Gold, and (4) X1 Blue. Micro-CT examinations #2 and #3 were performed after filling removal and repreparation, respectively. Next, all teeth were divided into 2 new groups (n = 20) according to the irrigant activation protocol: XP Clean (XP Clean size 25.02) and Flatsonic (Flatsonic ultrasonic tip). Micro-CT examination #4 was performed after irrigant activation. Statistical analysis was performed with a significance level set at 5%. Results WaveOne Gold removed a significantly greater amount of filling material than the manual group (p < 0.05). The time to reach the WL was similar for all reciprocating systems (p > 0.05). X1 Blue was faster than the manual group (p < 0.05). Only manual group improved the filling material removal after the repreparation stage (p < 0.05). Both activation protocols significantly improved the filling material removal (p < 0.05), without differences between them (p > 0.05). Conclusions None of the tested instruments completely removed the filling material. X1 Blue size 25.06 reached the working length in the shortest time. XP Clean and Flatsonic improved the filling material removal.

      • KCI등재

        What is known about the medicinal potential of bamboo?

        Janayne Gagliano,Fernanda Anselmo-Moreira,Wilton Ricardo Sala‑Carvalho,Cláudia Maria Furlan 경희대학교 융합한의과학연구소 2022 Oriental Pharmacy and Experimental Medicine Vol.22 No.3

        Bamboos are considered one of China’s four noble plants and have been used for medicinal purposes for centuries. Despite that, what is really known about the chemical composition and biological activities of bamboos? Which species have been studied? What trials have been done to test their medicinal properties? This paper compiled studies of the last 11 years about phytochemical and biological activities of bamboos aiming a critical analysis of the results to provide perspectives and direc‑ tions for future research using bamboo species as a potential source of drug leads. This review gathers available information on major scientifc databases from the period of 2007–2018. A total of 136 papers regarding 87 bamboo species and 24 genera were compiled. Studies regarding phytochemical and or bioactivity of species from the Olyreae tribe (herbaceous bamboo) were not found. Phenolic compounds were the major class of secondary metabolites reported for bamboos species, followed by coumarins and alkaloids. Antioxidant capacity was the most performed bioassay. Phyllostachys has been the most studied genus. This review highlights a big lack of knowledge regarding American bamboos, mainly for the herbaceous species. Although bamboos are known to have a diversity of favonoids, there are other classes of constituents that should be better studied. There are few bamboo species with their in vivo biological potential tested. Therefore, bamboos have economically important secondary metabolite classes with a possible medicinal application, but further studies on phytochemistry and in vivo assays are still needed to better evaluate their benefts to human health.

      • KCI등재
      • SCISCIESCOPUS

        THE <i>SPITZER</i> INFRARED SPECTROGRAPH SURVEY OF PROTOPLANETARY DISKS IN ORION A. I. DISK PROPERTIES

        Kim, K. H.,Watson, Dan M.,Manoj, P.,Forrest, W. J.,Furlan, Elise,Najita, Joan,Sargent, Benjamin,Herná,ndez, Jesú,s,Calvet, Nuria,Adame, Lucí,a,Espaillat, Catherine,Megeath, S. T.,Muz American Astronomical Society 2016 The Astrophysical journal Supplement series Vol.226 No.1

        <P>We present our investigation of 319 Class II objects in Orion A observed by Spitzer/IRS. We also present the follow-up observations of 120 of these Class II objects in Orion A from the Infrared Telescope Facility/SpeX. We measure continuum spectral indices, equivalent widths, and integrated fluxes that pertain to disk structure and dust composition from IRS spectra of Class II objects in Orion A. We estimate mass accretion rates using hydrogen recombination lines in the SpeX spectra of our targets. Utilizing these properties, we compare the distributions of the disk and dust properties of Orion A disks with those of Taurus disks with respect to position within Orion A (Orion Nebular Cluster [ONC] and L1641) and with the subgroups by the inferred radial structures, such as transitional disks (TDs) versus radially continuous full disks (FDs). Our main findings are as follows. (1) Inner disks evolve faster than the outer disks. (2) The mass accretion rates of TDs and those of radially continuous FDs are statistically significantly displaced from each other. The median mass accretion rate of radially continuous disks in the ONC and L1641 is not very different from that in Taurus. (3) Less grain processing has occurred in the disks in the ONC compared to those in Taurus, based on analysis of the shape index of the 10 mu m silicate feature (F-11.3/F-9.8). (4) The 20-31 mu m continuum spectral index tracks the projected distance from the most luminous Trapezium star, theta(1) Ori C. A possible explanation is UV ablation of the outer parts of disks.</P>

      • KCI등재

        Production of Bioactive Compounds with Antitumor Activity Against Sarcoma 180 by Pleurotus sajor-caju

        Ivaneliza Simionato Assis,Mariane Bonatti Chaves,Marcia Luciane Lange Silveira,Regina Maria Miranda Gern,Elisabeth Wisbeck,Agenor Furigo Ju´nior,Sandra Aparecida Furlan 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.11

        This work studied the influence of culture medium composition and pH on exopolysaccharide (EPS) production by Pleurotus sajor-caju and validates the antitumor activity of the produced EPSs and of the mycelial biomass (intracellular polysaccharides [IPSs]) against Sarcoma 180 (S180) cells. The effect of the initial concentrations of (NH4)2SO4, yeast extract and soy peptone on EPS production by P. sajor-caju was studied in shake flasks. A bioreactor was used to evaluate the pH values and the initial CaCO3 and glucose concentrations. Extracts of EPSs (PE1) and IPSs obtained through two different separation processes (PM1 and PM2) were tested on mice inoculated with S180 cells. A medium containing 2.5, 1.0, and 1.0 g/L of (NH4)2SO4, yeast extract and soy peptone, respectively, provided the highest EPS concentration (0.6 g/L). The use of pH 4.0, 1.0 g/L CaCO3 and 20 g/L initial glucose concentration enhanced EPS productivity (3.84 g/L per hour). The PE1 extract promoted the highest reduction of S180 growth (86%), followed by the PM2 extract (80%); growth reduction was doseindependent for both substances. This work provides information about culture medium and conditions that enhanced the production of extracellular polysaccharides by P. sajor-caju. The results can contribute to the search for new bioactive products bringing novel aspects to the medical and pharmaceutical areas.

      • KCI등재

        Post-emergence application of herbicides and growth regulators on soybean growth and agronomic performance

        Fabiula Patricia Novakoski,Leandro Paiola Albrecht,Alfredo Junior Paiola Albrecht,André Felipe Moreira Silva,Mateus Dalpubel Mattiuzzi,Tamara Thaís Mundt,Eduardo Seity Furlan Kashivaqui,Felipe Gustavo 한국작물학회 2020 Journal of crop science and biotechnology Vol.23 No.3

        Plant lodging is among the factors that limit the productive potential of the soybean crop. Growth regulators or even herbicides may be used in pre- and post-emergence of soybean to minimize the chance of lodging. These products can act to reduce plant height or the number of branches. This study aimed to evaluate the growth and agronomic performance of soybean under the post-emergence application of growth regulators and herbicides. Two experiments were conducted in Palotina, Paraná State (PR), Brazil. A randomized complete block design with four replications was used. Treatments consisted of the application mepiquat chloride, trinexapac, cloransulam, lactofen, and control (without application). Crop injury, chlorophyll indices, and variables related to growth and agronomic performance of soybean crop were evaluated. Post-emergence application of lactofen (36 g a.i. ha −1 ) or cloransulam (33.6 g a.i. ha −1 ) on soybean (V3–V4) reduced the height of soybean plants, but showed no negative eff ect on soybean yield. Therefore, these herbicides are alternatives to reduce the lodging of soybean plants. Post-emergence application of mepiquat chloride (100 g a.i. ha −1 ) was selective to soybean plants, but did not reduce plant growth. Trinexapac application (125 g a.i. ha −1 ) did not reduce plant growth and had a deleterious potential on soybean yield. Therefore, post-emergence application of trinexapac on soybean is not recommended.

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