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Primary intraosseous carcinoma of the mandible
Hwang, Eui-Hwan,Choi, Yong-Suk,Lee, Sang-Rae 대한구강악안면방사선학회 2005 Imaging Science in Dentistry Vol.35 No.4
A very uncommon tumor, primary intraosseous carcinoma (PIOC), is a carcinoma arising within the jaw. The definite diagnosis of PIOC is often difficult as the lesion must be distinguished from alveolar carcinoma that may invade the bone from the overlying soft tissues or from the tumors that have metastasized to the jaw from a distant site. A case of PIOC arising in the mandible is presented. The clinical, radiologic, and histologic features are described. This rare lesion should be considered in any differential diagnosis of a jaw radiolucency.
강원,경북지역 낙엽송 지위지수 적합성 평가에 관한 연구
이대성 ( Dae Sung Lee ),이의섭 ( Eui Sub Lee ),최종현 ( Jong Hyun Choi ),서영완 ( Yeong Wan Seo ),최정기 ( Jung Kee Choi1 ) 한국임학회 2014 산림과학 공동학술대회 논문집 Vol.2014 No.-
본 연구는 강원 및 경북지역의 낙엽송 지위지수의 적합도를 평가하기 위해 실시되었다. 연구자료는 강원 및 경북지역의 45개 낙엽송 인공림 표준지 조사로부터 우세목 1본을 선발하여 수간석 해를 통해 분석되었다. 산림청에서 개발된 지위지수표에 의거하여 본 연구대상지의 지위지수를 산정한 결과, 지위지수가 18 이하로 낮은 지역은 8곳(18%)이었으며, 지위지수가 20 이상으로 우수한 지역이 37곳(82%)으로서 대부분 지역에서 지위지수가 우세하였다. 지위지수곡선의 적합도를 평가하기위해 수간석해목의 과거에서 현재까지의 수고생장에 따른 지위지수의 변화를 도시한 결과, 초기 임령 때 지위지수와 차이가 없는 곳은 단지 8지역(18%)이었으며, 지위지수가 2∼4 m 차이가 발생한 지역이 19곳(42%), 6 m 이상 발생한 지역이 18곳(40%)으로 나타났다. This study was performed to evaluate the compatibility of site index for Larix kaempferi in Gangwon and Kyeongbuk regions. The data were collected and analyzed from stem alalysis of one dominant tree at each of 45 permanent plots installed in the regions. The result of site index estimation following the site index table developed by Korean Forest Service (KFS) showed that 8 plots (18%) were less than site index 18 and 37 plot (82%) greater than site index 20. Height growth changes of stemmed trees until present were illustrated in a graphic form to evaluate the compatibility of site index curve. The result showed that only 8 plots (18%) did not show any change of site index as trees age, 19 plots (42%) fluctuated in 2∼4m and 18 plots (40%) over 6m.
Sung-Ho Yoon,Min Jong Kil,Jun-Hyeok Jeon,Hyun-Mi Kim,Seul-Gi Kim,Jiye Han,Eui-Sung Lee,Youngmo An,Jin Woo Cho,Jihwan An,Jae-Boong Choi,Il Jeon,Hyeongkeun Kim 한국정밀공학회 2023 International Journal of Precision Engineering and Vol.10 No.5
A novel rotary-type atomic layer deposition (ALD) process for coating platinum thin film on three-dimensional (3D) substrates is demonstrated. High uniformity and conformability of the platinum thin-film deposition on 3D substrates were confirmed, ensuring the controllability of the new ALD technique. The results for this technique surpassed those of the conventional wet method and ordinary atomic layer deposition, which both have a limited specific surface area. To demonstrate the application of this new technology, Pt nano-film coated γ-Al2O3 was produced using the rotary-type ALD and applied to diesel oxidation catalysts (DOCs). The produced DOCs showed high Pt content when the number of ALD cycles was increased, and thereby exhibited more complete combustion of gaseous pollutants, such as CO, C3H8, and NO, even at lower temperatures. Pt nano-film deposition by the rotary-type ALD process was first optimised on Si wafer substrates. The process was controlled by four parameters: processing temperature, number of ALD cycles, precursor pulse time, and reactant pulse time. Deposition of the Pt nano-film was mainly determined by the processing temperature and the number of ALD cycles. The average growth per cycle and density of the Pt nano-film were found to be 0.8 Å/cycle and 21.0 g/cm3, respectively. The same procedure and conditions were applied to 3D γ-Al2O3 powder substrates for DOCs, which demonstrated greater conversion performance compared with conventional Pt-used DOCs.
Choi, Yoon Young,Joun, Jae Min,Lee, Jeewon,Hong, Min Eui,Pham, Hoang-Minh,Chang, Won Seok,Sim, Sang Jun Elsevier 2017 Bioresource technology Vol.244 No.2
<P><B>Abstract</B></P> <P>The aim of this study was to develop the economic and effective buffer system for microalgae mass cultivation using industrial flue gas. Due to the continuous flue gas supplement, culture media acidified, therefore cell growth inhibited. Although buffering agent was added, this result increase in cost for overall culture process. Therefore combined buffer system of bicarbonate and phosphate (BP) for large-scale use was investigated. The bicarbonate buffer system generated from CO<SUB>2</SUB> dissolution, additionally phosphate buffer system improves the buffer performance under the continuous CO<SUB>2</SUB> supplementation from flue gas. The microalgae <I>Haematococcus pluvialis</I> was cultivated under autotrophic outdoor conditions using these buffer solutions. As a result, the autotrophic BP buffer system enhanced the biomass and astaxanthin productivity of <I>H. pluvialis</I> to 105% and 103%, respectively. The results confirm that the BP buffer system reduces the cost of microalgal CO<SUB>2</SUB> conversion process, particularly for the outdoor mass cultivation.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Cost-effective bicarbonate/phosphate (BP) buffer system was developed. </LI> <LI> BP buffer showed stable buffer capacity under high concentration of 10% CO<SUB>2</SUB> gas. </LI> <LI> <I>H. pluvialis</I> showed maximal growth rate under conditions of BP buffer at 0.1M KOH. </LI> <LI> BP buffer was comparable to HEPES for astaxanthin production by <I>H. pluvialis</I>. </LI> <LI> Reliable autotrophic mass cultivation of <I>H. pluvialis</I> was achieved. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Eui Kyung Choi,Hyo-jeong Kim,Bo-Kyung Je,Byung Min Choi,Sang-Dae Kim 대한신경외과학회 2023 Journal of Korean neurosurgical society Vol.66 No.3
Objective : Owing to advances in critical care treatment, the overall survival rate of preterm infants born at a gestational age (GA) <32 weeks has consistently improved. However, the incidence of severe intraventricular hemorrhage (IVH) has persisted, and there are few reports on in-hospital morbidity and mortality. Therefore, the aim of the present study was to investigate trends surrounding in-hospital morbidity and mortality of preterm infants with severe IVH over a 14-year period. Methods : This single-center retrospective study included 620 infants born at a GA <32 weeks, admitted between January 2007 and December 2020. After applying exclusion criteria, 596 patients were included in this study. Infants were grouped based on the most severe IVH grade documented on brain ultrasonography during their admission, with grades 3 and 4 defined as severe. We compared in-hospital mortality and clinical outcomes of preterm infants with severe IVH for two time periods : 2007–2013 (phase I) and 2014–2020 (phase II). Baseline characteristics of infants who died and survived during hospitalization were analyzed. Results : A total of 54 infants (9.0%) were diagnosed with severe IVH over a 14-year period; overall in-hospital mortality rate was 29.6%. Late in-hospital mortality rate (>7 days after birth) for infants with severe IVH significantly improved over time, decreasing from 39.1% in phase I to 14.3% in phase II (p=0.043). A history of hypotension treated with vasoactive medication within 1 week after birth (adjusted odds ratio, 7.39; p=0.025) was found to be an independent risk factor for mortality. When comparing major morbidities of surviving infants, those in phase II were significantly more likely to have undergone surgery for necrotizing enterocolitis (NEC) (29.2% vs. 0.0%; p=0.027). Additionally, rates of late-onset sepsis (45.8% vs. 14.3%; p=0.049) and central nervous system infection (25.0% vs. 0.0%; p=0.049) were significantly higher in phase II survivors than in phase I survivors. Conclusion : In-hospital mortality in preterm infants with severe IVH decreased over the last decade, whereas major neonatal morbidities increased, particularly surgical NEC and sepsis. This study suggests the importance of multidisciplinary specialized medical and surgical neonatal intensive care in preterm infants with severe IVH.
Choi, A-Young,Choi, Ji Hyun,Hwang, Keun-Young,Jeong, Yeon Ju,Choe, Wonchae,Yoon, Kyung-Sik,Ha, Joohun,Kim, Sung Soo,Youn, Jang Hyun,Yeo, Eui-Ju,Kang, Insug Rapid Science Publishers ; Kluwer Academic Publish 2014 Apoptosis Vol.19 No.4
<P>Licochalcone A (LicA), an estrogenic flavonoid, induces apoptosis in multiple types of cancer cells. In this study, the molecular mechanisms underlying the anti-cancer effects of LicA were investigated in HepG2 human hepatocellular carcinoma cells. LicA induced apoptotic cell death, activation of caspase-4, -9, and -3, and expression of endoplasmic reticulum (ER) stress-associated proteins, including C/EBP homologous protein (CHOP). Inhibition of ER stress by CHOP knockdown or treatment with the ER stress inhibitors, salubrinal and 4-phenylbutyric acid, reduced LicA-induced cell death. LicA also induced reactive oxygen species (ROS) accumulation and the anti-oxidant N-acetylcysteine reduced LicA-induced cell death and CHOP expression. In addition, LicA increased the levels of cytosolic Ca(2+), which was blocked by 2-aminoethoxydiphenyl borate (an antagonist of inositol 1,4,5-trisphosphate receptor) and BAPTA-AM (an intracellular Ca(2+) chelator). 2-Aminoethoxydiphenyl borate and BAPTA-AM inhibited LicA-induced cell death. Interestingly, LicA induced phosphorylation of phospholipase Cγ1 (PLCγ1) and inhibition of PLCγ1 reduced cell death and ER stress. Moreover, the multi-targeted receptor tyrosine kinase inhibitors, sorafenib and sunitinib, reduced LicA-induced cell death, ER stress, and cytosolic Ca(2+) and ROS accumulation. Finally, LicA induced phosphorylation of vascular endothelial growth factor receptor 2 (VEGFR2) and c-Met receptor and inhibition of both receptors by co-transfection with VEGFR2 and c-Met siRNAs reversed LicA-induced cell death, Ca(2+) increase, and CHOP expression. Taken together, these findings suggest that induction of ER stress via a PLCγ1-, Ca(2+)-, and ROS-dependent pathway may be an important mechanism by which LicA induces apoptosis in HepG2 hepatocellular carcinoma cells.</P>
Choi, Jun Young,Han, Yong Woon,Jeon, Sung Jae,Ko, Eui Jin,Moon, Doo Kyung Elsevier 2019 SOLAR ENERGY -PHOENIX ARIZONA THEN NEW YORK- Vol.185 No.-
<P><B>Abstract</B></P> <P>We fabricated organic solar cells (OSCs) based on bulk-heterojunction photoactive layers with fullerene (PTB7:PC<SUB>71</SUB>BM) and non-fullerene (PBDB-T:ITIC) systems by introducing 1,8-diiodooctane (DIO) and 4-fluorobenzaldehyde (4-FBA) as co-additives, respectively. Introduction of the co-additives led to a uniform surface morphology of photoactive layer and formed well distributed interpenetrating networks between donors and acceptors. Carrier recombination were reduced due to the favorable structure for charge transport. Consequently, the devices with co-additives achieved an enhanced performance with a PCE of 8.5% (J<SUB>SC</SUB> = 16.4 mA/cm<SUP>2</SUP> and FF = 68.3%) in the fullerene system, and a PCE of 10.1% (J<SUB>SC</SUB> = 16.9 mA/cm<SUP>2</SUP> and FF = 67.8%) in the non-fullerene system. In addition, the devices with co-additives showed improved stabilities compared to those with single additives. Correspondingly, the reduction ratio of PCE at ambient atmosphere conditions decreased from 17.07% to 10.59% in the fullerene system, and 34.02% to 24.75% in the non-fullerene system.</P> <P><B>Highlights</B></P> <P> <UL> <LI> 4-Fluorobenzaldehyde used as co-additives in the fullerene and non-fullerene systems. </LI> <LI> Co-additives allowed the formation of a well-distributed molecular order. </LI> <LI> Co-additives formed more favorable structure for charge transport. </LI> <LI> Co-additives maintained the phase by preventing aggregation. </LI> <LI> The device with co-additives exhibit more stable at ambient atmosphere conditions. </LI> </UL> </P>