형제에서 발생한 신성 요붕증

김마리,김덕수,정혜천,박범수,하태선 충북대학교 의학연구소 2001 忠北醫大學術誌 Vol.11 No.1

신성 요붕증은 항이뇨 호르몬(antidiuretic hormone, arginine vasopressin)의 혈중 농도가 높음에도 불구하고 신장이 항이뇨 호르몬에 반응하지 못하여 생기는 유전 질환이다.신장이 항이뇨 호르몬에 반응하지 못하면 신장의 농도 조절 작용과 수분 재흡수의 기능이 상실되어 많은 양의 저장(hypotonic) 상태의 뇨를 체외로 배출하므로써 탈수증에 이르게 된다.저자들은 다음, 다뇨 및 성장 장애를 주소로 내원한 형제에서 임상 검사를 통하여 신성 요붕증을 진단하였다.형제 중 형은 8세 남아로 생후 10개월에 다음, 다뇨 및 발열을 주소로 내원하여 신성 요붕증을 진단 받고 치료를 시작하였으나, 보호자 자의로 약물 복용을 중단하였다.14개월 남아인 동생이 다음, 다뇨 및 성장 장애의 증상으로 내원하여 같은 방법으로 신성 요붕증을 진단받았고, 현재 형과 함께 이에 대한 치료를 받고 있다.저자들은 형제에서 발생한 신성 요붕증을 경험하였기에 문헌 고찰과 함께 보고하는 바이다. Nephrogenic diabetes insipidus is a genetic disease that the kidney cannot respond to a-ntidiuretic hormone in spite of elevated serum antidiuretic hormone.Failure of the kidney to respond to antidiuretic hormone result in decreased function of the kidney of osmore-gulation and water resorption, and therefore nephrogenic diabetes insipidus are present in large amount of hypotonic polyuria, polydipsia and dehydration.The authors experienced two case of nephrogenic diabetes insipidus in brothers who have polydipsia, polyuria and failure to thrive.One 8-year-old boy had been diagnosed as nephrogenic diabetes insipi- dus by clinical test at 7 years ago, but at 32 months of his age, his parents had disco- ntinued his medication.The other 14-month-old boy has been diagnosed nephrogenic di- abates insipidus by same method lately. So, we report two case of nephrogenic diabetes insipidus in brothers with the brief rev-iew of related literatures.

법과학적 응용을 위한 섬유의 동일성에 관한 연구(Ⅰ) : FT-IR, PY-GC에 의한 섬유의 동일성에 관한 연구 A Study on the Identification of Textile by FT-IR & Py-GC

김은호,김명덕,김재균,박하선,장성길,박성우 內務部 國立科學搜査硏究所 2002 國立 科學 搜査 硏究所 年報 Vol.34 No.-

제주항의 Vibrio parahaemolyticus 분포에 관한 연구

김재하,오덕철 제주대학교 해양연구소 1982 해양자원연구소연구보고 Vol.6 No.-

A survey of Vibrio parahaemolyticus distribution in Jeju harbor was carried out semimonthly for eight different sites from June to October 1981. The place shown the highest count was site 6 and site 7 while the lowest count was shown at site 8. In terms of season, August and September showed the highest while considerably low counts were shown in July and October. Regardless of seasons and sites. overall counts were within the range of 100/100ml~3000/100ml. Lower counts were shown in comparison with other coastal areas such as Busan, Masan and Ulsan harbor. Certain correlation was observed between counts and water temperature while no correlation was found with pH. It could be health hazardous to use untreated water and raw fishes caught from surveyed area in neighboring restaurants.

위암환자의 생존율에 관한 역학적 조사연구

김덕성,이태용,이영수,류기하 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2

To find out the survival rates of stomach cancer patients, the author studied 288 stomach cancer patients who took operation at the Department of Surgery in Chungnam National University Hospital from January 1, 1985 to December 31, 1991. The results were as follows: 1. Of the total patients, 67.4% were male: but 32.6% were female. 2. 64.6% of patients lived in rural area and 35.4% urban;98.3% of those were married; 30.6% were farmers and 17.4% were commercial workers; 54.5% were smokers; 48.3% were alcohol drinkers. 3. By types of gastric cancer, 84.4% were progressive gastric cancer patients. Among these, type 2 patients were more than other type patients. 61.5% of those had metastasis to lymph node. 55.2% of those took operation by RSG with gastrojejunostomy; 97.6% of those knew that they had cancer; 19.1% of those had a family history that at least one of family members had cancer. 4. The gross 5 year survival rate of total patients was 47.2%. 5. The 5 year survival rate of male patients was 41.6% but that of female was 46.3%. The 5 year survival rates by residential area, chemotherapy, marital status, blood type, family history, smoking, and drinking were not significantly different. 6. The 5 year survival rate of type 2 progressive gastric cancer patients was the highest with the rate of 72.0%. Metastasis to lymph node and type of operation showed statistically significant difference in 5 year survival rates.

동계 제주항의 미생물학적 수질오염에 관한 연구

오덕철,김재하 제주대학교 해양연구소 1980 해양자원연구소연구보고 Vol.4 No.-

Distribution of total coliform bacteria (T.C), fecal coliform bacteria (F C) and general bacteria (G.B)together with pH, water temperature and air temperature were surveyed periodically from December 1979 to 1980 at sic sites in Jeju Harbor. The sampling was done from both surface and bottom level for each sites. The average water temperature throughout the period of investigation was 15˚~16.75℃. It was indicated that at the estuary where a large amount of inland water is flowing in, the temperature of surface water showed lower than bottom layer. The lowest and the highest pH showed at site 4 and site I whose value were 7.83 and 8.33 respectively. Overall pH value throughout the investigation period was between 7.7 and 8.6. The highest viable counts of TC, FC and GB were observed on site 4 with 86,166/100ml, 9,208/100ml and 52,496/ml respectively, while the lowest counts were on site 1 with 245/100ml, 81/100ml and 425/ml respectively. Differences in counts between surface and bottom were not much agreeable throughout the tested sites, but surface levels were remarkably higher than bottom for every sites. The ratio of Fecal coliform to Total coliform(Fc : Tc) were ranged from 4.46 % to 37.9 % Reviewing the data obtained in this investigation, it is obvious that a large amount of fecal bacteria are flowing into Jeju harbor through untreated city sewage. Therefore, it is desirable to set up sewage disposal facilities in order to prevent serious pollution problems with pathogenic bacteria such as Salmonella ,Vibrio etc.

冬李 濟州港의 徵生物學的 水質汚染에 關한 硏究

吳德鐵,金在河 濟州大學 海洋資源硏究所 1980 해양과환경연구소 연구논문집 Vol.4 No.-

1979年 12月부터 1980年 1月까지 濟州港域의 6個所 海水를 採水하여 水層別로 Total Coliform(TC ), Fecal Coliform(FC) 및 General Bacteria (GB) 를 調査하고 pH, 水溫, 氣溫등도 함께 側定하였다. 水溫은 平均 15∼16.75℃ 였으며 陸水의 流入이 많은 곳은 表面數가 深層水보다 낮았다. pH는 陸水의 流入이 가장 많은 Site 4가 가장 낮아서 平均 7.83이였고 Site 1이 平均 8.33으로 가장 높았으며 全體的으로 全期間동안 7.7∼8.6 사이였다. TC, FC 數는 Site 4가 가장많아 100ml當 各各 86,166, 9,208이고 GB는 ml 當 52,496 個體였으며, 가장 낮은 쪽은 Site 1로서 各各 100ml當 245,81 및 ml당 425 個體였다. 水層別로는 採水場所에 따른 差異는 있으나 모든 곳이 다 表層이 越等히 많았다. FC와 TC 比率은 全般的으로 4.46에서 37.9% 사이였다. 調査된 資料를 分析할때 多量의 奮便性 細菌이 濟州市 下水를 通하여 濟州港으로 流入되고 있음이 나타났고, Salmonella 등 病原性 細菌의 存在가 예상되어 下水의 處理가 要望된다. Distribution of total coliform bacteria (T. C), fecal coliform bacteria ( F C ) and general bacteria ( G. B) together with pH, water temperature and air temperature were surveyed periodically from December 1979 to January 1980 at six sites in Jeju Harbor. The sampling was done form both surface and bottom level for each sites. The average water temperature throughout the period of investigation was 15℃∼16.75 ℃. It was indicated that at the estuary where a large amount of inland water is flowing in, the temperature of surface water showed lower than bottom layer. The lowest and the highest pH showed at site 4 and site 1 whose value were 7.83 and 8.33 respectively. Overall pH value throughout the investigation period was between 7.7 and 8.6. The highest viable counts of TC, FC and GB were observed on site 4 with 86, 166/100ml, 9,208/100ml and 52,496/ml respectively, while the lowest counts were on site 1 with 245/100ml, 81/100ml and 425/ml respectively. Differences in counts between surface and bottom were not much agreeable throughout the tested sites, but surface levels were remarkably higher than bottom for every sites. The ratio of Fecal colifom to Total coliform (Fc:Tc) were ranged from 4.46 % to 37. 9 %. Reviewing the data obtained in this investigation, it is obvious that a large amount of fecal bacteria are flowing into Jeju harbor through untreated city sewage. Therefore, it is desirable to set up sewage disposal facilities in order to prevent serious pollution problems with pathogenic bacteria such as Salmonella, Vibrio etc.

전공의들의 직업적 유해인자 및 직업만족도

송혜란,김진하,변주현,이광영,이덕희,김호찬 大韓産業醫學會 2003 대한직업환경의학회지 Vol.15 No.3

목적: 전공의는 여러 유해인자에 노출되어지고 있으며 과중한 업무로 인한 수면 부족에 시달리고 있다. 본 연구는 전공의의 건강상태의 기초 자료를 제공하고 향후개선 방안을 도출하기 위하여 시행하였다. 방법: 연구대상은 2000년 3사관학교와 국군군의학교에 입소한 전체 1,316명 중 전공의 수련과정 없이 입대한 의사와 치과의사, 한의사를 제외한 881명을 대상으로 설문지를 배포하여 784부(회수율: 89.0%)를 회수하고 이중 분석이 가능한 704(79.9%)명의 자료를 최종 분석하였다. 결과: 월평균 당진횟수는 레지던트 1년차에서 19회 정도이었다. 당직 시 평균 수면시간은 레지던트 1년차에서 4시간미만 이었다. 수련기간 동안 전공의의 20%이상에서 방사선, 레이저, 살균소독제, 마취가스, 항암제에 노출되었으며 예방대책은 방사선과 레이저의 노출의 경우 35%정도를 제외하고는 10%내외로 조사되었다. 연구대상자중 91.1%에서 수련기간 동안 주사침이나 시술에 의해 손상을 입었으며 그 중 본인이 감염된 경우는 HBV 2.3%(4명), HCV 0.6%(1명)으로 조사되었다. 응답자의 28.4%에서 자신의 직업에 불만족 하였으며 96.5%가 과중한 업무부담을 느꼈고 69.5%가 동일한 임금수준에서 직업을 바꾸고자 한다고 응답하였다. 결론: 전공의는 수련기간 동안 물리적, 화학적, 생물학적 유해인자에 노출되고 있었으나 이에 대한 보호나 예방대책은 거의이루어지지 않고 있었으며 과중한 업무부담으로 수면부족을 초래하여 가장 중요한 환자 진료에 지장을 받고 있었다. 수련기간 동안 대다수가 의사로서 직업에 대한 흥미를 가지고 있었으나 업무부담과 진료이외의 업무 등으로 소득과 조건이 비슷하다면 다른 직업을 선택하고자 하였다. 이상의 결과를 토대로 전공의들을 위한 유해인자의 보호대책 및 예방대책을 마련하며 과중예방대책이 마련되어야 하고 업무환경개선 및 업무로 인한 건강장해에 대한 정당한 보상이 향후에 마련되어야 할 것이다. Objects: Residents are exposed to various hazards and harassed by sleep dificiency due to overwork. This study was performed to outline the health condition of residents and develop the ways of improving it. Mehtods: A questionnaire was distributed to 881 army doctors who enrolled at the Korea Third Military Academy and The Armed force Health Service School in 2000 with the exception of medical doctors who joined the armed service without going through intern and resident periods, dental and oriental medical doctors. 784(89.0%) of the 881 questionnaires were resident of which 704 cases (79.9%). This should actually be 89.0% were regarded for analyses as being reliable data. Results: More than 20% of residents were exposed to radiation, laser, disinfectants, anesthetic gas, and anticancer drugs during their training periods with preventive neasures for each of these hazards taken in about 10% of the cases of the lesser hazards but in about 35% for the hazards from radiation and laser. 91.1% of residents had experience of needlestick injuries during theirtraining periods with over 36.3% being exposed to patients with infection during that time. The cases contracting HBV and HCV diseases due to pricking are 2.3% and 0.6% respectively. The average number of night duties per month during a one-year resident's period was about 10. The average sleeping time on duty during a one-year residents was less than 4 hours. 28.4% of respondents were not satisfied with their occupation, 96.5% delt tired from overwork and 69.5% wanted to change their occupation to another that would pay the same salary. Conclusion: Residents are exposed to harmful physical, chemical and biological factors, but the preventive care seldom undertaken. In addition, their overwork brings about lack of sleep which causes them problems when giving medical treatment to patients during their training periods. Despite the resident's interest in an occupation as a doctor, many intend to select other occupations if they can receive the same salary. According to the above results, preventative systems and measures should be prepared with environmental improvements for residents, and proper rewards for their overwork should be accomplished

알루미늄 合金 熔接材의 疲勞破壞에 미치는 殘留應力의 影響에 關한 硏究

차용훈,김하식,김덕중 한국공작기계학회 1995 한국생산제조학회지 Vol.4 No.4

This study is to inspect the influence of the initial residual stress on fatigue crack growth behavior after the distribution of the initial residual stress is measured when the crack is growing from the compressive residual stress field to the tensile residual stress field. Also, the influence of the variation of residual stress distribution on fatigue crack growth behavior at the crack tip is studied when the initial crack occurs on weld metal, bead interface and HAZ (Heat Affected Zone), respectively. For this purpose, CT-type specimen that crack parallel to the welding bead were manufactured by butt welding on the Al. Alloy 1100-O plate.

신경회로망을 이용한 용접잔류응력 예측에 관한 연구

차용훈,김일수,김하식,이연신,김덕중,성백섭,서준열 韓國工作機械學會 2000 한국생산제조학회지 Vol.9 No.6

In order to achieve effective prediction of residual stresses, the series experiment were carried out and the residual stress-es were measured using the backpropagation algorithm from the neural network and the sectional method. Using the experimental results, the optiomal control algorithms using a neural network should be developed in order to reduce the effect of the external disturbances on residual stresses during GMA welding processes. The results obtained from the comparison between the measured and calculated results, showed that the neural network based on backpropagation algorithm can be used in order to control weld quality. This system can not only help to under-stand the interaction between the process parameters and residual stress, but also, improve the quantity control for welded structures. The development of the system is goal in this study.

신경회로망을 이용한 용접잔류응력 예측 및 최적의 용접조건 선정에 관한 연구

차용훈,김하식,이연신,김덕중,성백섭 朝鮮大學校 機械技術硏究所 2000 機械技術硏究 Vol.3 No.1

The objective of the study is the development of the system for effective prediction of residual stresses using the back propagation algorithm from the neural network. The achieve of this goal, the series experiment were carried out and measured the residual stresses using sectional method. Using the experimental results, the optional control algorithms using a neural network should be developed in order to reduce than the effect of the external distribution during GMA welding processes. Also, comparison with the measured and the calculated results from the FEM(finite element method) and verification of the developed system was carried out. This system can not only help to understand the interaction between the process parameters and residual stress, but also, improve the quantity control for welded structures. Then the results obtained from this study are as follows. Through comparison between the measured and calculated results, the neural network based on back propagation algorithm is the best techniques to predict the process parameter. A new techniques which predict the process parameter such as welding voltage, arc current, welding speed using the training the raw dates, will be proposed.