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야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로
조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6
Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.
김종덕,장재익,유문일,정흥우,권찬호,오두식,김창현 한국국제농업개발학회 2004 韓國國際農業開發學會誌 Vol.16 No.1
본 시험은 크릴 분말의 사료적 특성을 조사하고, 산란계 사료에 첨가하였을 때 계란의 생산성과 품질을 비교하기 위하여 수해하였다. 크릴 분말을 산란계 사료에 0, 1 및 2% 수준으로 첨가하여 216수에 6주간 사양시험을 실시하였다. 크릴분말의 일반성분은 수분 8.25%, 조단백질 50.52%, 조지방 16.67%, 조회분 15.72%로 단백질과 지방이 높은 동물성 사료원료였다. 그리고 무기질(15.72%), astaxanthin (10ppm) 및 콜레스테롤 함량 (780ppm) 또한 많았다. 산란율, 연파란율, 일일사료섭취량 및 난중은 처리간에 유의적인 차이가 없었다. 황고 및 난황색도는 크릴의 첨가수준이 높을수록 유의적으로 높아 산란계의 난질을 향상시키는 첨가제로서의 가능성을 보였다. 이상의 결과를 볼 때 크릴 분말은 단백질과 지방이 높은 동물성 사료이며, 산란계에서 천연착색제로의 가능성을 보였다. This experiment was conducted to evaluate the chemical composition of Antarctic Krill(Euphausia superba Dana) meal as feed, and to investigate the effect of its supplementation on productivity and egg quality of laying hen. A total of 216 layers at the age 43 weeks in commercial cage were fed for 6 weeks with 3 different diets containing 0, 1, and 2% Krill meal (KM). The chemical composition of KM was consisted of moisture 8.25%, crude protein 50.52%, crude fat 16.67%, curde ash 15.72%, indicating that KM contains large amount of protein and fat. Krill meal also contains large amounts of mineral(15.72%), astaxanthin(10ppm) and cholesterol(780ppm). No differences were found in egg production, broken and soft eggs, and feed intake among treatments. Dietary supplementation of KM resulted in increased egg yolk height(6.1㎜) and yolk color (2) compared with those of control, suggesting that KM can be used as a feed additive for yolk quality improvement. According to the results of this study, Krill meal can be supplemented in laying hen diets as protein and fat sources, and natural coloring pigment.
Aflatoxin B_1과 Vitamin A가 發生中인 白鼠의 肝에 미치는 影響
李斗泳,朴景蘭,盧承武,金源式 충남대학교 의과대학 지역사회의학연구소 1990 충남의대잡지 Vol.17 No.2
For the study on the effect of aflatoxin B_1 and vitamnin A on the developing fetal rat liver, aflatoxin B_1(1mg/kg, Sigma Chemicals) was administered intraperitoneally on the 8th day of pregnancy and vitamin A (50,000IU/day, Sigma Chemicals) was administered orally from the 8th day of pregnancy to a day before sacrifice daily. Under ether anesthesia, removed uterus, opened the pregnant sac, and fetuses were fixed in the 10% neutral buffered formalin solution. The 5㎛ thick liver specimens were stained with H-E and the mitotic figures were counted under high power field(x400) of light microscope. The results were as followings: 1. Aflatoxin B_1 inhibited the liver cell mitosis. 2. On the 14th day of development, vitamin A inhibited the antimitotic effect of aflatoxin B_1.
안면부, 유방 및 상완부에 발생한 홍반성 루푸스 지방층염 1예
송유근,손두식,명형준,이현정,임중규,김순호,김윤아 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2
Lupus erythematous panniculitis is a chronic inflammatory disease of subcutaneous fat that occurs in 2-3% of patients with systemic lupus erythematosus. Lupus erythematous panniculitis typically presents with firm, indurated subcutaneous nodules or plaques commonly developed in proximal extremities, trunks, head and neck. Face, breast and upper extremities involvement with lupus erythematous panniculitis has been infrequently reported. We report a case of lupus erythematous panniculitis developed in a 27-year-old female confirmed by histologic features and laboratory findings.
Kim, Wi-Sik,Jung, Sung-Ju,Kim, Du-Woon,Kim, Seok-Ryel,Kim, Jeong-Ho,Oh, Myung-Joo The Korean Society of Fisheries and Aquatic Scienc 2010 Fisheries and Aquatic Sciences Vol.13 No.1
Since 1998, a new viral disease with high mortality has been consistently recorded in Korea in cultured carp, Cyprinus carpio. In this study, we investigated an epizootic of the disease that caused high mortality rates in carp obtained from 11 farms in Korea between 1999 and 2007. Assessment of koi herpesvirus (KHV) levels in diseased carp was carried out to determine if this virus was the etiologic agent of disease in this instance. High mortality rates in carp were recorded mainly in the spring and autumn at water temperatures between $19^{\circ}C$ and $24^{\circ}C$. Diseased fish typically showed surface discoloration, with a thick opaque mucus covering the body and gills. Protozoan parasites and bacteria were recovered from 7/29 (24%) and 2/26 (8%) of fish, respectively. Evidence of viral infection was marked; cytopathic effects (CPEs), characterized by cell rounding and an extended cytoplasm in fathead minnow (FHM) cells, were detected in 40/41 fish (98%). A high mortality rate (80%) resulted when supernatants of cell cultures showing CPEs were applied to previously healthy fish. KHV was detected by polymerase chain reaction in 6/41 fish (15%), but was not detected in supernatants obtained from cell cultures showing CPEs. These results suggest that KHV may not be the etiologic agent of the high mortality occurring among cultured carp in Korea; therefore, some other-as yet unidentified-infective agent must be responsible.
Kim, Wi-Sik,Jung, Sung-Ju,Kim, Jong-Oh,Kim, Du-Woon,Kim, Jeong-Ho,Oh, Myung-Joo The Korean Society of Fish Pathology 2011 한국어병학회지 Vol.24 No.1
Viral haemorrhagic septicaemia virus (VHSV) is an epidemic virus in olive flounder Paralichthys olivaceus farms in Korea, since the virus have first isolated in 2001. In the present study, partial glycoprotein (G) gene nucleotide sequences of seven Korean VHSV from cultured olive flounder and wild marine fishes in coastal areas of Korea were analyzed to evaluate their genetic relatedness to worldwide isolates. Phylogenetically, all Korean VHSV formed only one minor cluster including Japanese isolates, in genotype IVa, while the North America isolates formed a different minor cluster in genotype IVa. These results suggest that Korean VHSV could be an indigenous virus in Korean and Japanese coastal areas, but have not been introduced from North America.
Kim, Du Sik,An, Jeong Mi,Lee, Han Gil,Seo, Su Ryeon,Kim, Seon Sook,Kim, Ju Yeon,Kang, Jeong Wan,Bae, Yun Soo,Seo, Jeong Taeg Informa Healthcare 2013 Free radical research Vol.47 No.2
<P>Staurosporine, a non-specific protein kinase inhibitor, has been shown to induce neurite outgrowth in PC12 cells, but the mechanism by which staurosporine induces neurite outgrowth is still obscure. In the present study, we investigated whether the activation of Rac1 was responsible for the neurite outgrowth triggered by staurosporine. Staurosporine caused rapid neurite outgrowth independent of the ERK signaling pathways. In contrast, neurite outgrowth in response to staurosporine was accompanied by activation of Rac1, and the Rac1 inhibitor NSC23766 attenuated the staurosporine-induced neurite outgrowth in a concentration-dependent manner. In addition, suppression of Rac1 activity by expression of the dominant negative mutant Rac1N17 also blocked the staurosporine-induced morphological differentiation of PC12 cells. Staurosporine caused an activation of NADPH oxidase and increased the production of reactive oxygen species (ROS), which was prevented by NSC23766 and diphenyleneiodonium (DPI), an NADPH oxidase inhibitor. Staurosporine-induced neurite outgrowth was attenuated by pretreatment with DPI and exogenous addition of sublethal concentration of H<SUB>2</SUB>O<SUB>2</SUB> accelerated neurite outgrowth triggered by staurosporine. These results indicate that activation of Rac1, which leads to ROS generation, is required for neurite outgrowth induced by staurosporine in PC12 cells.</P>