역해석법에 의한 침하 및 압밀도 분석

배종순,권민재,김민아,김동숙 경상대학교 생산기술연구소 2003 工學硏究院論文集 Vol.19 No.-

This study is the analysis for settlement and degree of consolidation with Compression Index(Cc) and Coefficient of Consolidation(Cv) that is changed due to Consolidation using the actual measurement through a back-analysis method based on the least squares method. We were try to decide the expected settlement and the time of filling removal by using the degree of consolidation which is the closest to the settlement behavior by actual measurement. At the ground improvement construction site proposed for Gwangyang container Port, we meet good results as follows; With regard to the settlement by actual measurement before the completion of loading filling, it is estimated that Barron's method(Sr/Sm=100.4%) is closer to the settlement by actual measurement than Hansbo method (Sr/Sm=78.8%), due to external influences such as immediate settlement or equipment load. After the completion of loading filling, while Asaoka's method (Sr/Sm=109.1%) and Barron's method(Sr/Sm=112.8%) were overvalued, Hyperbolic method(Sr/Sm=70.0%) was undervalued, and Hansbo method(97.6%) showed the most similar results to the settlement by actual measurement. The results of this study showed that, in applying the consolidation parameter obtained by means of back-analysis, Barron's method was the most appropriate before the completion of loading filling, while after it Hansbo's method was, with 99.4% of the settlement by actual measurement.

GC 및 활성탄에 의한 알킬 치환 페놀류의 분자면적 추정

배선영,안형신,김건,이동선 서울여자대학교 자연과학연구소 1996 자연과학연구논문집 Vol.7 No.-

Activated carbons were prepared from leaves of Ginkgo biloba by activation process with zinc chloride after carbonization. The specific surface area of this activated carbon measured by BET surface analyzer was obtained as 469.8㎡/g. Adsorption of alkyl substituted phenols on activated carbon was determined using gas chromatography. It was found that molecular area could be estimated using Langmuir's isotherm, specific surface area, and Avogadro's number. Molecular areas for phenol, 2-ethyl phenol, 2,5-dimethyl phenol, 2-isopropyl phenol were 0.0288n㎡, 0.0796n㎡, 0.0384n㎡, and 0.1182n㎡, respectively. This estimation techniques are potentially useful to obtain molecular area for various compounds.

L1210 세포에 대한 약용 식물의 세포독성 검색

배기환,민병선,도동선,김남수,양기종,안병준 충남대학교 약학대학 의약품개발연구소 1992 藥學論文集 Vol.8 No.-

For the research of cytotoxic natural products, 50 medicinal plants were extracted with benzene and methanol, separately, and screened against L1210 cells. From the results(Table I), 6 samples showed cytotoxicity both in benzene and methanol extracts of 17 samples in benzene extracts and 3 samples in methanol extracts, respectively. Generally, the cytotoxicity exhibited high frequency (34%) in benzene extract but low frequency in methanol extract(6%), it meant that active cytotoxic components had less polarity. ED_50 values less than 10 ㎍/㎖ were observed in 17 medicinal plants.

기왕 제왕절개 반흔 부위에 착상한 자궁외 임신의 보존적 치료 3례

박선영,박혜인,김윤숙,김종수,최승도,선우재근,배동한 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

In past decade, ectopic pregnancy developing in the previous cesarean section scar has been the rarest forms of ectopic pregnancy and very dangerous because of the risk of uterine rupture and hemorrhage. These pregnancies once carried a maternal mortality rate of 40% to 45%, and until recent years they usually resulted in abdominal hysterectomy as a life-saving procedure. However, increased awareness of the importance of preserving childbearing capacity has led to several successful attempts at conservative management that include intraamniotic and systemic methotrexate administration, suction curettage followed by insertion of an intracervical 30-mL Foley catheter ballooning and angiographic artery embolization. We present three cases of ectopic pregnancy developing in the previous cesarean section scar in which successfully treated with conservative management.

Glow放電法에 의한 α-Si蒸着裝置의 製作과 그 試料의 特性

유동선,현옥배,고년규,황정남,정원모,이철주 연세대학교 자연과학연구소 1981 學術論文集 Vol.7 No.-

Glow방전법에 의해서 SiH_4를 분해하여 α-Si 박막을 얻을수 있는 장치를 제작하였다. 이 SiH_4기체는 수소기체속에서 10%로 희석되였으며, 진공방전함속에서 rf 전압에 의하여 분해된 Si는 유리기판위에 증착된다. α-Si박막은 1~1.6 A˚/sec의 증착율로 약 7000 A˚의 두께까지 증착되였다. α-Si 박막의 흡수계수는, 2.3 eV의 photon energy 영역에서 약 10^4 cm^-1이고, 그 optical gap은 약 2.1 eV였다. 이 박막의 증착율은 전극간격에 따라 변하고 있으나, 최적전극간격과 기체유입량은 각각 2.6cm와 1~2cc/min였다. Apparatus capable of producing α-Si film by the glow discharge method was designed and constructed in this study. The monosilane gas which is diluted in H_2 gas to 10% is decomposed in the reaction chamber by rf oscillation. The apparatus is composed of a reaction chamber, a rf generator, a cooling system, etc. The α-Si thin film is produced at a deposition rate of 1~1.6 A˚/sec to a thickness of about 7000 A˚. Its absorption coefficient is about 10^4 cm^-1 in the photon energy region of ~2.3 eV, and its optical gap is about 2.1 eV. The deposition rate for the film is controlled by varying the distance between electrode and substrate. The optimum distance and gas flow is about 2.6 cm and 1~2 cc/min, respectively.

난치성 만성정신분열증 환자의 생활의 질에 미치는 정신사회치료 프로그램의 효과에 대한 예비연구

송동호,배민진,이종호,이홍식,김선경,서호석,김찬형,전지용 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.4

Objects : Recent studies of psychosocial adjustment after hospitalization have found that the combination of maintenance antipsychotic drug treatment and psychosocial treatment including psychoeducational program are highly predictive of social rehabilitation and reduction of subsequent relapse. Two groups of patients with refractory chronic schizophrenia were preliminarily compared to determine the effect of a psychosocial treatment program on the quality of life in refractory chronic schizophrenics in an open comparative trial. Methods : One group(N=11) was assigned to approximately six months of the psychosocial treatment program(including psychoeducation program and activity program such as interpersonal relationship program, social skill training, self management program, outings, etc), in a group format, twice a week and a fixed maintenance dosage of clozapine ; while scale(QLS) was used to provide an objective measure of changes in patient's psychosocial functioning and a general assessment of psychopathology was made using the Brief Psychiatric Rating Scale(BPRS). Results : Both BPRS total positive score and the QLS total score, especially in the intrapsychic foundation factor of the scale showed a statistically significant improvement in the psychosocial treatment group. But there was no significant change in both BPRS and QLS scores over a 6-month period in the non-psychosocial treatment group. A significant negative correlation was found between the negative symptom and changes of QLS total, instrumental role and common object and activities scores respectively after receiving a 6-month of the psychosocial treatment program. Conclusion : These results suggest that a psychosocial treatment program including the integration of psychoeducation and a skill training oriented activity program serve as an outpatient treatment modality to improve the quality of the life in refractory chronic schizophrenia. To further clarify the effect of psychosocial treatment in chronic schizophrenia, a randomized trial should be done.

흰쥐 경동맥 손상 모형에서 체외 방사선조사에 의한 신내막 과증식억제 : Intercellular Adhesion Molecule-1과 Vascular cell Adhesion Molecule-1의 역할 The Possible Role of Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule-1

강동헌,승기배,장기육,임상현,정해억,임효영,김연실,채장성,김재형,홍순조,최규보 대한순환기학회 1999 Korean Circulation Journal Vol.29 No.9

大氣汚染物質의 變異原性에 關한 硏究 : 마우스 母體 및 胎仔의 小核試驗을 中心으로

韓東宣,車喆煥,張聖薰,裵思相 고려대학교 의과대학 1989 고려대 의대 잡지 Vol.26 No.3

This Study aimed at identifying the cytogenic effect of air pollutants in pregnant mouse and her fetus. Samples of air pollutants were collected by the high volume air sampler in several sites of Seoul from May through December in 1988. Total suspended particulates (TSP) were measured and those of benzene and methanol were extracted and dissolved in dimethyl sulfoxied (DMSO). Those were injected into peritoneal cavity by the concentration and the micronucleated polychromatic erythrocyte (MNPCE) was observed in the bone marrow of mother mice. IN addition, the liver of fetus was extracted and MNPCE was observed. Transplacental genetic toxicity due to air pollutants in both cases was measured in the end. 1. In case of the tar concentration equivalent to those residing in the volume of 100m³ of air, the MNPCEs in the mother's bone marrow were 0.57±0.15% and 0.70±.20% in Shinchon; 0.27±0.17% and 0.40±0.13 In Jungrung and in the underground shopping center ; 0.33±0.10% and 0.55±0.13% in the subway station. The MNPCEs measured in the sample of the tunnels, of which tar concentration was equivalent to that in 50m³ and 100m³ of air, were 0.86±0.24% and 1.06±0.17% in tunnel A and 0.70±0.15% and 0.96±0.23% in tunnel B; those were the highest MNPCE in the samples of mother mice. 2. The MNPCEs measured in the liver of featus were 0.60±0.25% and 0.80±0.15% in Shinchon. In Jungrung and the underground shopping center, the MNPCEs in the liver of fetus were the same as those in mothers. In the sample of the subway station, the MNPCEs in the liver of fetus, 0.73±0.20%, were higher than in mothers only in the 200? tar concentration. The MNPCEs in the 50m³ and 100m³ tar concentration were 0.87±0.10% and 1.27±0.27% in tunnel A, and 0.68±0.41% and 1.07±0.23% in tunnel B. It showed that the MNPCEs only in the 100m³ tar concentration were higher than those in mothers.

GC 머무름시간을 이용한 알데히드 동족체의 열역학적 상수 측정

李東宣,裵善瑛,金建,金炫廷,李恩聖 서울여자대학교 대학원 1999 論文集 Vol.- No.7

Thermodynamic parameters of a homologous serious of n-aldehydes were determined by using gas chromatographic retention data, distribution coefficient and following relationships : ??, ??, ??. From the retention data at several temperatures under isothermal conditions, a plot of lnk versus 1/T was generated, and the enthalpy and entropy changes were calculated from the slope and intercept, respectively. The standard free energy value change calculation of the transition between the stationary phase and the mobile phase results in negative value in the most cases, indicating a spontaneous process. The relationship between the standard free energy and the number of carbon atoms in the homologue was linear under isothermal conditions, and the linear relationship between free energy change and temperature was accurately determined. The information applicable to the prediction of retention times using numerical simulation was obtained.

정상인에서 베타3-아드레날린 수용체 유전자의 변이가 복부 비만도 및 지질대사에 미치는 영향

김영선,윤석기,김철희,서교일,김학선,김극배,변동원,유명희 순천향의학연구소 1998 Journal of Soonchunhyang Medical Science Vol.4 No.1

The β₃-adrenergic receptor is expressed in visceral adipose tissue in humans and is thought to contribute to the regulation of the resting metabolic rate and lipolysis. We studied the influence of a mutation in the β₃ -adrenergic receptor gene(Trp64Arg) on body fat distribution, central obesity, lipid metabolism in 65 healthy young male adults. One out of 65 subjects were homozygous (Arg/Arg) for the trp64Arg mutation, 17 subjects were heterozygous (Trp/Arg), and 47 lacked the mutation(Trp/Trp). The body weight, height, body mass index, waist-to-hip ratio were similar between the subjects with- and without the mutation. Total body fat, abdominal fat amount, body fat distribution, serum total- and HDL-cholesterol, triglyceride, glucose, and insulin concentrations were also not different according to the presence or absence of the mutation. These results suggested that Trp64Arg mutation in β₃-adrenergic receptor gene is not a major contributing factor for central obesity or change in lipid metabolism in Korean young adults.