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      • KCI등재

        알코올중독 환자의 예후 예측에 관한 연구(Ⅰ) : 사회문화적 및 심리적 변인을 중심으로

        이정균,성상경,전동환 大韓神經精神醫學會 1995 신경정신의학 Vol.34 No.4

        Objects : The purpose of the study was to identify the prognosis-predicting indicators in alcoholics by the correlations between prognosis and sociocultural, psychological factors and drinking history. Methods : The subjects were composed of 50 alcoholics including 25 psychiatric inpatients(drinking group) and 25 alcoholics abstinent for 6 months or more after discharge(abstinent group). They were investigated with interview, questionnaire and review of their charts. Results : The results were as follows : 1) Abstinent group showed higher percentage of marriage and more stable martial status than drinking group. 2) Abstinent group got more stable employments before abstinence than drinking group. 3) Abstinent group had been admitted more voluntarily and had therapeutic participation, such as alcoholics anonymous or outpatient care, than drinking group after discharge. 4) Abstinent group had longer maximal length of abstinence than drinking group. Conclusions : With the above results, the authors think that social stability, attitude toward the treatment, therapeutic participation after discharge and maximal length of abstinence could be the important prognosis-predicting indicators for alcoholic.

      • KCI등재

        Lithium Carbonate의 腦및 其他 組織分布와 電解質에 미치는 影響에 關한 實驗的 硏究

        Dong Soo Choi,Chung Kyoon Lee 대한신경정신의학회 1975 신경정신의학 Vol.14 No.4

        Lithhmi 이 臨床的으로 情緒障碍治療에 利用되 기 始作한것은 最近에 와서 活發해 졌다. 그러 나 其効果의 作 用機轉은 아직 明 白치 않음으로 Lithium carbonate 를 動物에 投與하여 腦및 其他 組織에 어떻게 分布되며 다 른 電解質과의 關係가 어떤지를 究明하고 其作用機轉을 理解하고져 本實驗을 施行하여 다음과 같은 結果를 얻었다. 1. Lithium 分布는 腦뿐아니라 ᄎ部分의 器官組織에서 :大量短期投與群에서 少量長期投與群보다 濃度가 높 았다. 그러 나 腦下垂趙와 副臀에서는 그렇지 않다. 2. 腦의 Na. K. ion 澳度는 正常群보다 ᄎ置短期投 與群에서 減少되었고 Ca. ion 澳度는 血獎澳度가 가장 낮은 * 量短期間投與群과 正常群의 差異가 거의 없고 Mg•의 血猜澳度는 :大量短期投與群에서 가장 높았으나 腦組織의 漠度는 正常群과 別差없다. 3. 正常群에서는 筋과 腦에 비 숫한 Lithium 이 存在하나 量短期投與群에서는 筋組織으로의 浸透速度가 빠 르고 많다. 4. Lithium Carbonate 投與後 各祖織에 서 의 電解質 變化를 보면 다음과 같다.血獎에 서는 Ca. ion 이 大量短期投與群에 서 正常群보다 減少하나 少量長期投與群에서는 多少 増加하였다. 血獎, 赤血球및 臀에 서 Mg 値가 Lithium carbomate 投與群에서 上昇하였고 筋에서는 正常群과 比較해서 K• 와 Ca• 이 增加, Ca• 는 骨에 서 는 減少하고 심 장, 肝,臀에서는 增加했다. 5. RBC/plasma Ratio 는 正常群보다 大量經期投與群에서 上昇하였고 少量長期投與群에서는 더욱 上昇하 였다. 이 것은 赤血球의 Lithiumᅳup-talce 가 느리 다는 것을 意味한다.

      • Reconstruction of Large Bone and Soft Tissue Defect Combined with Infection in the Lower Extremity with Free Flap Followed by Ipsilateral Vascularized Fibular Transposition

        Chung, Duke Whan,Han, Chung Soo,Lee, Jae Hoon,Kim, Eun Yeol,Park, Kwang Hee,Kim, Dong Kyoon 대한미세수술학회 2013 Archives of reconstructive microsurgery Vol.22 No.2

        Purpose: The aim of this study is to report on the results and discuss the role of free flap followed by ipsilateral vascularized fibular transposition (IVFT) for reconstruction of large bone and soft tissue defect combined with infection by open tibia fracture. Materials and Methods: During the research period, lasting from December 2002 to June 2008 (Kyung Hee University Medical Center), data were collected from three patients who underwent IVFT after free flap. We analyzed the successiveness and persistency of the infection using free flapping, bone union, and hypertrophy between transposed fibula and tibia. Results: Regarding free flap, successive results were observed in all examples. In the final follow-up results, transposed fibulas all survived, having hypertrophy similar to that of adjacent tibia. Conclusion: Reconstruction of tibia defect with free flap followed by IVTF is a useful and safe method for avoidance of the potential risk of infection for patients with a large tibial bone defect and soft tissue defect associated with infection.

      • KCI등재

        Lithium Carbonate distribution and its effects on the other ions in the brain and the other tissue of rats

        Hahn, Dong Soo,Lee, Chung Kyoon 大韓神經精神醫學會 1975 신경정신의학 Vol.14 No.4

        Lithium이 臨床的으로 情緖障碍治療에 利用되기 始作한 것은 最近에 와서 活發해 졌다. 그러나 其效果의 作用機轉은 아직 明確치 않음으로 Lithium carbonate를 動物에 投與하여 腦 및 其他 組織에 어떻게 分布되며 다른 電解質과의 關係가 어떤지를 究明하고 其作用機轉을 理解하고져 本實驗을 施行하여 다음과 같은 結果를 얻었다. 1. Lithium分布는 腦뿐아니라 大部分의 器官組織에서 大量短期投與群에서 小量長期投與群보다 濃度가 높았다. 그러나 腦下垂體와 副腎에서는 그렇지 않다. 2. 腦의 Na. K. ion濃度는 正常群보다 大量短期投與群에서 減少되었고 Ca. ion濃度는 血漿濃度가 가장낮은 大量短期投與群과 正常群의 差異가 거의 없고 Mg.의 血漿濃度는 大量短期投與群에서 가장 높았으나 腦組織의 濃度는 正常群과 別差없다. 3. 正常群에서는 筋과 腦에 비슷한 Lithium이 存在하나 大量短期投與群에서는 筋組織으로의 浸透速度가 빠르고 많다. 4. Lithium Carbonate 投與後 各組織에서의 電解質變化를 보면 다음과 같다. 血漿에서는 Ca. ion이 大量短期投與群에서 正常群보다 減少하나 小量長期投與群에서는 多少 增加하였다. 血漿, 赤血球 및 腎에서 Mg値가 Lithium carbonate 投與群에서 上昇하였고 筋에서는 正常群과 比較해서 K. Ca.이 增加, Ca.는 骨에서는 減少하고 심장, 肝, 腎에서는 增加했다. 5. RBC/plasma Ratio는 正常群보다 大量短期投與群에서 上昇하였고 小量長期投與群에서는 더욱 上昇하였다. 이것은 赤血球의 Lithium-up-take가 느리다는 것을 意味한다. 1. Infiltration and distribution rates of lithium into the brain as well as most organs except hypophysis and adrenal glands were higher in the group received large quantity for short period than in the group received small dose for longer period. 2. Concentration of Na and K ions in the brain were lower in the group received large doses for shorter period than in the controls. There was no significant difference in the level of Ca ion concentration between the controls and the group which received large doses for short period and which also showed the lowest plasma level. Plasma level of Mg was highest in the group received large doses for short period but the concentration of Mg in the brain was almost same as in the controls. 3. In the control group the amount of lithium is almost same in the muscle and in the brain, but in the group received large doses for short period the infilteration rate of lithium was higher and the amount of the infiltrate was larger in the muscle. 4. The changes of electrolites in the various tissues after administration of lithium carbonate were as follows: In plasma Ca ion decreased more in the group received large doses for short period than in the controls but in the group received small amount for longer period it rather increased a little. In the groups that received lithium, level of Mg in plasma, RBC and the kidney increased, K and Ca increased in the muscles in comparison with the controls, and Ca decreased in the bones and increased in the heart, liver and kidney. 5. RBC/plasma ratio increased more in the group received large doses for short period than in the control group, and it increased much more in the group received small dose for longer period. This suggests lithium uptake of RBC is slow.

      • KCI등재
      • SCIESCOPUSKCI등재

        Influence of Panaxatriol-type Saponin on Secretion of Catecholamines from Isolated Perfused Rabbit Adrenal Gland

        Kim, Dong-Yoon,Choi, Cheol-Hee,Kim, Chong-Dae,Kim, Kyoon-Hong,Kim, Soo-Bok,Lee, Byeong-Joo,Chung, Myung-Hyun The Pharmaceutical Society of Korea 1989 Archives of Pharmacal Research Vol.12 No.3

        In the previous observations, it was reported that both total ginseng saponin and panaxadiol revealed the marked secretory effect of catecholamines (CA) from the rabbit adrenal gland and that CA secretion induced by them is due to dual mechanisms, cholinergic action and the direct action. In the present study, an attempt to investigate the effect of panaxatriol-type saponin (PT), which is known as an active component of Korean ginseng, on the secretion of CA from the rabbit adrenal gland was made. PT(200 $\mu$g) administered into adrenal vein evoked significantly secretion of CA from the isolated perfused rabbit adrenal gland. Secretory effect of CA produced by PT was attenuated clearly by treatment with chlorisondamine or adenosine, but was markedly increased by physostigmine. Perfusion of Krebs solution containing PT (200 $\mu$g) for 30 min potentiated greatly secretion of CA induced by acetylcholine. PT-induced CA secretion was weakened considerably by ouabain treatement or perfusion of calcium-free Krebs solution. These experimental data demonstrate that PT releases CA from the isolated perfused rabbit adrenal gland by a calcium-dependentd exocytotic mechanism. It seems that the secretory effect of PT is caused through the release of acetylcholine form cholinergic terminals present in the adrenal gland and a direct action on the chromaffin cell itself.

      • KCI등재
      • SCOPUSKCI등재

        A new contrast ratio measurement method using image patterns

        Choi, Dong-Wook,Yang, Sun-A,Bae, Jae-Woo,Lee, Seung-Bae,Chung, Ho-Kyoon The Korean Infomation Display Society 2011 Journal of information display Vol.12 No.2

        The contrast ratio is one of the most important performance parameters for display devices. The general method of measuring the contrast ratio is to determine the ratio of the full-screen white pattern to the full-screen black pattern, according to the Video Electronics Standards Association standard. Real TV images seldom have these images, however, and the conventional method does not reflect the true performance of the display in actual use. In this paper, a new contrast ratio measurement method that uses image patterns is proposed, to demonstrate that active matrix organic light-emitting diode TVs have a higher contrast than LED (LCD) TVs.

      • κ-є 모형의 난류점성상수 C<SUB>μ</SUB> 에 관한 연구

        정명균(Myung Kyoon Chung),김동훈(Dong Hun Kim),소홍윤(Hong Yun So) 대한기계학회 2009 대한기계학회 춘추학술대회 Vol.2009 No.11

        The turbulent eddy viscosity coefficient C<SUB>μ</SUB> that assumes constant value in the standard κ-? model is found to be a function of the time scale ratio Sκ/ε in boundary-free homogeneous shear flows. This functional form is derived by analyzing homogeneous turbulent shear flows. When such a functional coefficient C<SUB>μ</SUB> is applied to near-wall region of wall bounded flows, a universal wall damping function ?(y?) can be observed. And when it is applied to symmetric wake region of channel flows and free shear flows, it is found that there exists a universal wake function W(y/δ). Further when the functional coefficient C<SUB>μ</SUB> is applied to the outer part of free shear flows such as jets, wakes and mixing layers, it seems feasible to define a well-behaving function G(?) that takes account of the intermittency effect on the turbulent eddy viscosity.

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