니세틸 정(아세틸 - 엘 - 카르니틴 500mg)에 대한 뉴로세틸 정의 생물학적 동등성

조혜영,오인준,이용복,임동구,문재동,심영순,김은아,정현철 한국약제학회 2001 Journal of Pharmaceutical Investigation Vol.31 No.1

Acetyl-L-carnitine (ALC), an endogenous component of the L-carnitine family, is naturally occurring molecule synthesized from L-carnitine (LC) by carnitine acetyl transferase. ALC has been shown to improve the cognitive performance of patients suffering from dementia of the Alzheimer's type and proposed for treating Alzheimer's disease in pharmacological doses. The purpose of the present study was to evaluate the bioequivalence of two ALC tablets, Nicetile^(TM) (Dong-A pharmaceutical Co., Ltd.) and Neurocetil^(TM) (Kyung-Dong Pharmaceutical Co., Ltd.), according to the guidelines of Korea Food and Drug Administration. Twenty six normal male volunteers, 22.80±2.76 year in age and 63.07±7.98 ㎏ in body weight, were divided into two groups and a randomized 2 × 2 cross-over study was employed. After one tablet containing 500 ㎎ of ALC was orally administered, blood was taken at predetermined time intervals and the concentrations of ALC in serum were determined using HPLC with fluorescence detector. Because of the presence of endogenous ALC, the calibration was performed using dialyzed serum. Pharmacokinetic parameters such as AUC_t, C_(max) and T_(max) were calculated and ANOVA was utilized for the statistical analysis of the parameters. The results showed that the differences in AUC_t, C_(max) and T_(max) between two tablets were 2.72%, -0.65% and -8.42%, respectively, when calculated against the Nicetile^(TM) tablet. The powers (1-β) for AUC_t and C_(max) were 94.87% and 87.17%, respectively. Minimum detectable differences (△) at α=0.05 and 1-β=0.8 were less than 20% (e.g., 15.58% and 19.16% AUC_t and C_(max), respectively). The 90% confidence intervals were within ±20% (e.g., -11.84∼6.41 and -10.57∼11.88 for AUC_t and C_(max), respectively). Two parameters met the criteria of KFDA for bioequivalence, indicating that Neurocetil^(TM) tablet is bioequivalent to Nicetile^(TM) tablet.

스폰서십의 광고효과에 관한 연구

오준석,노동연 龍仁大學校 體育科學硏究所 2003 體育科學硏究論叢 Vol.13 No.1

This study was performed to find information which can utilize for their marketing and advertisement strategy by defining the difference between the brand image and its loyalty of the University students in the case of 2002-2003 Anycall pro-basketball title sponsorship. To achieve this purpose, 300 University students in SeoulㆍKyunggi areas were asked to respond on the questionnaires and only 286 responses had been analyzed. The method of Cronbach'a was used to verify the validity of this questionnaire then brand image revealed .8706 and brand loyalty was marked .8845. The SPSS WIN 11.0 program had been used to analyze the data, correlation and regression techniques were applied. The findings of this study were as follows: First, the statistics showed that the brand loyalty had a significant difference about social image, sensual image and its recognition, and brand image has 39.6%(R^(2)=.396) of influence about its loyalty. Second, the attitudinal loyalty had a significant difference about social image, sensual image and its recognition, and brand image has 40.9%(R^(2)=.409) of influence about its loyalty. Third, behavioral loyalty showed a significant difference about social image, sensual image and its recognition, and brand image had 32.9%(R^(2)=.329) of influence about its loyalty.

다발성 뇌수막종

박상준,박세혁,신동익,오세문 대한신경외과학회 1998 Journal of Korean neurosurgical society Vol.27 No.12

뇌동맥류 수술후 원격부위에 발생한 뇌실질내 출혈

박상준,오세문,신동익,박세혁 대한신경외과학회 1999 Journal of Korean neurosurgical society Vol.28 No.4

족부 재건에 유리조직이식술의 응용

오석준,이동락 大韓成形外科學會 1990 Archives of Plastic Surgery Vol.17 No.2

Over the past 7 years we have used five sources of free fla tissue transfers in 16 patients to reconstruct defects of the foot. These included groin, instep, dorsalis pedis, latissimus dorsi, axallary free flap. In these, not only skin flap but also tendocutaneous, osteocutaneous flaps were applied. All except two cases were successful in restoration of form and improvement of function. From an analysis of these cases, we have developed indications for various transfers based on the functional needs of the area involved. For the reconstruction of dorsum of the foot, the groin flaps were suitable in need of bones, and latissimus dorsi muscle flap with split thickness skin graft were suitable in need of tendon reconstruction. This method of reconstructions should be considered when loncal tissuese are not suitable for foot reconstruction.

타이틀 스폰서십 활동에 따른 브랜드이미지가 브랜드인지도 및 브랜드충성도에 미치는 영향

오준석,노동연 龍仁大學校 體育科學硏究所 2004 體育科學硏究論叢 Vol.14 No.1

This study is designed to shed a light on the Influence of title sponsorship activity among brand image, brand recognition and brand loyalty. 400 Korean Professional Football customers were chosen from football stadiums located in Seoul, Suwon, Sungnam and Bucheon. Among 400 questionnaires distributed and collected, 65 were excluded from the study because they were not either thoughtfully or completely answered. As a result, only 335 questionnaires were adopted and analyzed. This paper utilizes the statistical data analysis methods including correlation analysis and regression analysis. The findings acquired based on the aforementioned research methods and data analysis are as follows: First, social image showed a significant difference about brand recognition, and brand recognition had 24.3%(R^(2)=.243) of influence about social image. Second, sensorial image showed a significant difference about brand recognition, and brand recognition had 22.4%(R^(2)=.224) of influence about sensorial image. Third, social image showed a significant difference about brand loyalty, and brand loyalty had 26.4%(R^(2)=.264) of influence about social image. Fourth, sensorial image showed a significant difference about brand loyalty, and brand loyalty had 21.2%(R^(2)=.212) of influence about sensorial image. Fifth, brand recognition showed a significant difference about brand loyalty, and brand loyalty had 24.0%(R^(2)=.240) of influence about brand recognition.

조직공학적 연골생성에 있어서 연골막의 필요성

오경석,김해진,이동준,정재호,최준혁 大韓成形外科學會 2001 Archives of Plastic Surgery Vol.28 No.4

경남지역 건강검진자에서의 혈청지질에 관한 연구

정준훈,박현모,류재오,조동자,표미순,오은경 한국건강관리협회 2000 건협 Report Vol.3 No.-

토지이용의 효율성 제고에 관한 연구 : 묘지공원의 개선방안을 중심으로 on the cemetery park

권준오,김순곤,설동진 조선대학교 국토개발연구소 1994 국토개발연구 Vol.14 No.2

As unbanization and population have been increasing, cometerys have caused a lot of social problems. In order to improve these, a cemetery park with various functions like cemetery and park should be made. A cemetery park can provide neighboring people as well as cemetery users with spaces for relaxation and graves. Therefore the purpose of this study is to suggest basic directions for efficient policy which can change people's way of thinking about a propitious grave site and form new land culture. The conclusions are : First, in the aspect of system, laws related to burial and cemetery-grave size, and structures-should be changed in pace with people's consiousness and the rationalization of land. Second, in the aspect of administration, roads to cemetery parks, landscape and facilities should be prepared. And the plan should be made which neglected or unknown graves can be checked to be put in charnel. Besides by analyzing good and bad points of old cemetery, better ones should be made. It should take the department concerned and experts to manage the efficient policy for cemetery. Third, in the aspect of people's consciousness constant publicity activites about the efficient use of land will help to solve a sense of incompatibility caused by using excessive use of cemetery. Fourth, as this research shows, enough greenbelt and parking areas must be prepared with landscape, facilities and management improved.

교근 절개술을 이용한 관골골절의 관혈적 정복술

김일동,정철훈,이동락,오석준 大韓成形外科學會 1991 Archives of Plastic Surgery Vol.18 No.1

Open reduction with internal fixation of the displaced zygoma fractures is necessary to avoid facial asymmetry, ocular dysfunction, and masticatory impairment. Generally the tripod malar fractures have been treated with two-point fixation. But secondary malposition can develop as a result of masseter pull. Masticatory forces can both rotate and displace zygoma. So the two-point rim fixation may be indadequate to stabilize the tripod malar fracture against the tonic downward pull of the masseter muscle, especially if the thin lateral wall of the maxillary antrum has been damaged. Authors attempted to treat the tripod malar fractures with the simultaneous use of the three-point or four-point fixation and the masseter muscle myotomy at the origin. Postsurgical depression did not recur in follow-up, which was common in the standard Open Reduction and internal fixation procedures.