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      • Calixarene-based chemosensors by means of click chemistry.

        Song, Miaomiao,Sun, Zhongyue,Han, Cuiping,Tian, Demei,Li, Haibing,Kim, Jong Seung Wiley-VCH 2014 Chemistry - An Asian Journal Vol.9 No.9

        <P>Click chemistry, a new strategy for organic chemistry, has been widely used in the chemical modification of calixarenes because of its reliability, specificity, biocompatibility, and efficiency. Click-derived triazoles also play a critical role in sensing ions and molecules. This in-depth review provides an overview of calixarene-based chemosensors that incorporate click-derived triazoles, and their three characteristics (chromogenic, fluorescence, and wettability) are reviewed.</P>

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        Synthesis of hierarchical α-Fe<sub>2</sub>O<sub>3</sub> nanotubes for high-performance lithium-ion batteries

        Gu, Cuiping,Song, Xinjie,Zhang, Simin,Ryu, Si Ok,Huang, Jiarui Elsevier 2017 JOURNAL OF ALLOYS AND COMPOUNDS Vol.714 No.-

        <P><B>Abstract</B></P> <P>Hierarchical α-Fe<SUB>2</SUB>O<SUB>3</SUB> nanotubes are facially synthesized via a sacrificial template strategy without chemical etching, and are then employed as the anode material for lithium-ion batteries (LIBs). FeC<SUB>2</SUB>O<SUB>4</SUB>·2H<SUB>2</SUB>O nanorods are used as the sacrificial template to prepare nanotubes consisting of numerous nanosheets. The resultant hierarchical hollow structures possess an inter-diameter range of 400–600 nm and exhibit a large specific surface area. The as-prepared hierarchical nanotubes demonstrate remarkable improvement in cycling stability (500 cycles) and a reversible Li<SUP>+</SUP> storage capacity as high as 764.2 mAh g<SUP>−1</SUP> at a current density of 0.5 A g<SUP>−1</SUP>. This excellent electrochemical performance suggests that the hierarchical α-Fe<SUB>2</SUB>O<SUB>3</SUB> nanotubes prepared herein are promising candidate anode materials for LIBs.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Hierarchical α-Fe<SUB>2</SUB>O<SUB>3</SUB> nanotubes were obtained via a sacrificial template strategy. </LI> <LI> The hierarchical α-Fe<SUB>2</SUB>O<SUB>3</SUB> nanotubes exhibited high lithium ion storage performance. </LI> <LI> High performance was attributed to the tubular structure and large surface area. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>Hierarchical α-Fe<SUB>2</SUB>O<SUB>3</SUB> nanotubes obtained via a sacrificial template strategy followed by calcination process, showed excellent lithium ion storage performances.</P> <P>[DISPLAY OMISSION]</P>

      • KCI등재

        Pseudolaric Acid B Inhibits Proliferation, Invasion and Epithelial-to-Mesenchymal Transition in Human Pancreatic Cancer Cell

        Xiaoyu Li,Xianzhi Zhao,Wen Song,Zibin Tian,Lin Yang,Qinghui Niu,Qi Zhang,Man Xie,Bin Zhou,Yonghong Xu,Jun Wu,Cuiping Zhang 연세대학교의과대학 2018 Yonsei medical journal Vol.59 No.1

        Purpose: This study was aimed to investigate the effect of pseudolaric acid B (PAB) on proliferation, invasion and epithelial-to-mesenchymal transition (EMT) in pancreatic cancer cells and to explore the possible mechanism. Materials and Methods: The pancreatic cancer cell line SW1990 was cultured and treated with PAB dose- and time-dependent manners. Cell proliferation and invasion ability were measured by MTT assay and Matrigel/Transwell test, respectively. Semi-quantitative real-time polymerase chain reaction and Western blotting were conducted to detect the expression of EMT markers and the key molecules. Finally, nude mice subcutaneous transplantation tumor model was used to confirm the therapy efficacy of PAB. Results: PAB could inhibit SW1990 cell proliferation and invasion in time- and dose-dependent manners. Vimentin, fibronectin, N-cadherin, Snail, Slug, YAP, TEAD1, and Survivin were down-regulated (p<0.01), while E-cadherin, caspase-9, MST1, and pYAP were up-regulated (p<0.05). Combined PAB and gemcitabine treatment markedly restricted the tumor growth compared with gencitabin or PAB alone groups. Conclusion: PAB could inhibit the proliferation and invasion ability of pancreatic cancer cells through activating Hippo-YAP pathway and inhibiting the process of EMT.

      • KCI등재

        Chicken RNA-binding protein T-cell internal antigen-1 contributes to stress granule formation in chicken cells and tissues

        Yingjie Sun,Pin Zhang,Hang Zheng,Luna Dong,Lei Tan,Cuiping Song,Xusheng Qiu,Ying Liao,Chunchun Meng,Shengqing Yu,Chan Ding 대한수의학회 2018 Journal of Veterinary Science Vol.19 No.1

        T-cell internal antigen-1 (TIA-1) has roles in regulating alternative pre-mRNA splicing, mRNA translation, and stress granule (SG) formation in human cells. As an evolutionarily conserved response to environmental stress, SGs have been reported in various species. However, SG formation in chicken cells and the role of chicken TIA-1 (cTIA-1) in SG assembly has not been elucidated. In the present study, we cloned cTIA-1 and showed that it facilitates the assembly of canonical SGs in both human and chicken cells. Overexpression of the chicken prion-related domain (cPRD) of cTIA-1 that bore an N-terminal green fluorescent protein (GFP) tag (pntGFP-cPRD) or Flag tag (pFlag-cPRD) induced the production of typical SGs. However, C-terminal GFP-tagged cPRD induced notably large cytoplasmic granules that were devoid of endogenous G3BP1 and remained stable when exposed to cycloheximide, indicating that these were not typical SGs, and that the pntGFP tag influences cPRD localization. Finally, endogenous cTIA-1 was recruited to SGs in chicken cells and tissues under environmental stress. Taken together, our study provide evidence that cTIA-1 has a role in canonical SG formation in chicken cells and tissues. Our results also indicate that cPRD is necessary for SG aggregation.

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