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WEIGHTED ESTIMATES FOR CERTAIN ROUGH SINGULAR INTEGRALS
Zhang, Chunjie Korean Mathematical Society 2008 대한수학회지 Vol.45 No.6
In this paper we shall prove some weighted norm inequalities of the form $${\int}_{R^n}\;|Tf(x)|^pu(x)dx\;{\leq}\;C_p\;{\int}_{R^n}\;|f(x)|^pNu(x)dx$$ for certain rough singular integral T and maximal singular integral $T^*$. Here u is a nonnegative measurable function on $R^n$ and N denotes some maximal operator. As a consequence, some vector valued inequalities for both T and $T^*$ are obtained. We shall also get a boundedness result of T on the Triebel-Lizorkin spaces.
Weighted estimates for certain rough singular integrals
Chunjie Zhang 대한수학회 2008 대한수학회지 Vol.45 No.6
In this paper we shall prove some weighted norm inequalities of the form [수식] for certain rough singular integral T and maximal singular integral T*. Here u is a nonnegative measurable function on Rn and N denotes some maximal operator. As a consequence, some vector valued inequalities for both T and T* are obtained. We shall also get a boundedness result of T on the Triebel-Lizorkin spaces. In this paper we shall prove some weighted norm inequalities of the form [수식] for certain rough singular integral T and maximal singular integral T*. Here u is a nonnegative measurable function on Rn and N denotes some maximal operator. As a consequence, some vector valued inequalities for both T and T* are obtained. We shall also get a boundedness result of T on the Triebel-Lizorkin spaces.
Survival Association and Cell Cycle Effects of B7H3 in Neuroblastoma
Zhang, Haibo,Zhang, Jinsen,Li, Chunjie,Xu, Hao,Dong, Rui,Chen, Clark C.,Hua, Wei The Korean Neurosurgical Society 2020 Journal of Korean neurosurgical society Vol.63 No.6
Objective : The function of B7H3, a member of the B7 family of proteins, in neuroblastoma (NB) remains poorly characterized. Here we examine the expression pattern of B7H3 in clinical NB specimens and characterize the phenotype of B7H3 knock-down in NB cell line. Methods : Immunohistochemical (IHC) staining was carried out to assess the expression of B7H3 in clinical NB specimens. Survival association was analyzed using five Gene Expression Omnibus (GEO) datasets (GSE85047, GSE45480, GSE62564, GSE16476, GSE49710). Clonogenic survival and flow cytometry were performed after B7H3 knockdown to assess the cellular proliferation and cell survival in vitro. Impact of B7H3 silencing on NB growth was examined in vivo using the SH-SY5Y xenograft model. Results : On IHC staining, B7H3 was widely expressed in clinical NB specimens. Analysis of the transcriptional profiles of five GEO datasets clinically annotated NB specimens revealed that decreased B7H3 expression was associated with improved overall survival. B7H3 knockdown suppressed the proliferation of the SH-SY5Y NB model in vitro and in vivo. Cell cycle analysis revealed that B7H3 silencing induced G1/S arrest. This arrest was associated with the suppression of E2F1 expression and induction of Rb expression. Conclusion : Our results demonstrate that B7H3 expression correlate with clinical survival in NB patients. Preliminary studies suggest that B7H3 may mediate the G1/S transition.
Chunjie Zhao,Yiqing Wu,Min Zhang,Rui Liu 연세대학교의과대학 2016 Yonsei medical journal Vol.57 No.5
Purpose: Diabetic nephropathy (DN) is a prevalent chronic microvascular complication of diabetes mellitus involving disturbancesin electrolytes and the acid-base balance caused by a disorder of glucose metabolism. NHE1 is a Na+/H+ exchanger responsiblefor keeping intracellular pH (pHi) balance and cell growth. Our study aimed to investigate roles of NHE1 in high glucose (HG)-induced apoptosis in renal tubular epithelial cells. Materials and Methods: Renal epithelial tubular cell line HK-2 was cultured in medium containing 5 mM or 30 mM glucose. Then, cell apoptosis, oxidative stress, NHE1 expression, and pHi were evaluated. NHE1 siRNA and inhibitor were used to evaluate its role in cell apoptosis. Results: HG significantly increased cell apoptosis and the production of reactive oxygen species (ROS) and 8-OHdG (p<0.05). Meanwhile, we found that HG induced the expression of NHE1 and increased the pHi from 7.0 to 7.6 after 48 h of incubation. However,inhibiting NHE1 using its specific siRNA or antagonist DMA markedly reduced cell apoptosis stimulated by HG. In addition, suppressing cellular oxidative stress using antioxidants, such as glutathione and N-acetyl cysteine, significantly reduced the productionof ROS, accompanied by a decrease in NHE1. We also found that activated cyclic GMP-Dependent Protein Kinase Type I (PKG) signaling promoted the production of ROS, which contributed to the regulation of NHE1 functions. Conclusion: Our study indicated that HG activates PKG signaling and elevates the production of ROS, which was responsible for the induction of NHE1 expression and dysfunction, as well as subsequent cell apoptosis, in renal tubular epithelial cells.
( Xianchao Qin ),( Chunjie Li ),( Yueshu Gao ),( Zhenjia Zhang ),( Xiaojun Zhang ) 한국미생물생명공학회(구 한국산업미생물학회) 2019 Journal of microbiology and biotechnology Vol.29 No.4
An advanced anaerobic expanded granular sludge bed (AnaEG) and an internal circulation (IC) reactor, which were adopted to treat starch processing wastewater (SPW) and ethanol processing wastewater (EPW), were comprehensively analyzed to determine the key factors that affected the granules and microbial communities in the bioreactors. The granule size of 900 μm in the AnaEG reactor was smaller than that in the IC reactor, and the internal and external morphological structures of the granular sludge were also significantly different between the two types of reactors. The biodiversity, which was higher in the AnaEG reactor, was mainly affected by reactor type. However, the specific microbial community structure was determined by the type of wastewater. Furthermore, the dominant methanogens of EPW were mainly Methanosaeta and Methanobacterium, but only Methanosaeta was a major constituent in SPW. Compared with the IC reactor, characteristics common to the AnaEG reactor were smaller granules, higher biodiversity and larger proportion of unknown species. The comparison of characteristics between these two reactors not only aids in understanding the novel AnaEG reactor type, but also elucidates the effects of reactor type and wastewater type on the microbial community and sludge structure. This information would be helpful in the application of the novel AnaEG reactor.
Distributed smoothed rank regression with heterogeneous errors for massive data
Yuan Xiaohui,Zhang Xinran,Wang Yue,Wang Chunjie 한국통계학회 2023 Journal of the Korean Statistical Society Vol.52 No.4
Rank estimation methods are robust and highly efficient for estimating linear regression model. This paper investigates the rank regression estimation for massive data. To deal with the situation that the data are distributed heterogeneously in different blocks, we propose a weighted distributed rank-based estimator for massive data, which can improve the efficiency of the standard divide and conquer estimator. Under mild conditions, the asymptotic distributions of the weighted distributed rank-based estimator is derived. To achieve sparsity with high-dimensional covariates, the variable selection procedure is also proposed. Both simulations and data analysis are included to illustrate the finite sample performance of the proposed methods.
Semantic Annotation of Ontology by Using Rough Concept Lattice Isomorphic Model
Hongsheng Xu,Ruiling Zhang,Chunjie Lin,Wenli Gan 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.2
Semantic annotation is the process based on ontology annotation concept class, attribute and other metadata for cyber source and its various parts. Ontology mapping is to calculate the similarity between two ontology elements. Ontology merging is two or more source ontology merging into a goal Ontology. The basic principle of the concept lattice isomorphic generating is isomorphic to the background of the isomorphic concept lattice, and as concept lattice isomorphic background can generate the concept lattice. This paper analyzes the methods of ontology mapping and merging based on rough concept lattice isomorphic model and presents semantic annotation of ontology by using rough concept lattice isomorphic model. Experiments show that this method is better than the traditional method in semantic annotation accuracy and breadth.
Qisi Lin,Ling Zhang,Dongzhi Yang,Zhao Chunjie 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.6
This study describes the characterization of essential oil and phenolic compounds in Disporopsis pernyi (Hua) Diels. The essential oil was analyzed by gas chromatography-mass spectroscopy (GC-MS) and twelve volatile bioactive compounds of D. pernyi were identified. Polyphenols were identified by reverse-phase high-performance liquid chromatography (RP-HPLC) coupled to electrospray ionization time-of-flight mass spectrometry (ESI-TOF-MS) and quantified by ultrahigh-performance liquid chromatography (UPLC). A total of 4 polyphenolic compounds found in extract were identified as rutin, luteolin, quercetin, and betulinic acid. All obtained extracts and the 4 polyphenolic compounds were evaluated for their antimicrobial and antioxidant properties. The results suggested that the phenolic compounds contributed significantly to the antioxidant and antimicrobial activities of the plant.