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( Qiu Chun Li ),( Ya Chen Hu ),( Yin Fei Wu ),( Xiao Chun Wang ),( Xiao Lei Xie ),( Ming Xin Tao ),( Jun Lei Yin ),( Zhi Jie Lin ),( Yang Jiao ),( Li Juan Xu ),( Xinan Jiao ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.5
As Salmonella enterica serovar Pullorum remains a major economic problem for the poultry industries of countries with no efficient control measures, we presented a multidrug resistance strain S06004 (isolated from a clinically sick chicken in China in 2006) for genome sequencing. The genome comparison showed that the strain contained two prophages, the ST104 and prophage-4 (Fels2) of E. coli LF82, which were not detected in the only published genomes of S. Pullorum RKS5078 and CDC1983-67. In addition, the GyrA Ser83 point mutation, drugresistant genes, and many antibiotic pump systems that are present in S06004 may be contributing to the multidrug resistance of this strain.
Optical Properties of K9 Glass Waveguides Fabricated by Using Carbon-Ion Implantation
Chun-Xiao Liu,Wei Wei,Li-Li Fu,Xu-Feng Zhu,Hai-Tao Guo,Wei-Nan Li,She-Bao Lin 한국물리학회 2016 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.69 No.2
K9 glass is a material with promising properties that make it attractive for optical devices. Ion implantation is a powerful technique to form waveguides with controllable depth and refractive index profile. In this work, optical planar waveguide structures were fabricated in K9 glasses by using 6.0-MeV C3+-ion implantation with a fluence of 1.0 × 1015 ions/cm2. The effective refractive indices of the guided modes were measured by using a prism-coupling system. The refractive index change in the ion-irradiated region was simulated by using the intensity calculation method. The modal intensity profile of the waveguide was calculated and measured by using the finite difference beam propagation method and the end-face coupling technique, respectively. The transmission spectra before and after the implantation showed that the main absorption band was not influenced by the low fluence dopants. The optical properties of the carbon-implanted K9 glass waveguides show promise for use as integrated photonic devices.
Springback analysis of the stiffened panel milling from the bent plate
Chun-Guo Liu,Tao Yue,Xiao-Tong Yu 한국정밀공학회 2019 International Journal of Precision Engineering and Vol.20 No.2
An analytical method considering the redistribution of residual stress in the bent plate is proposed to predict the springback of the stiffened panel when milling the panel layer by layer. Two types of stiffened panel, namely, a panel with crosswise stiffeners and a panel with lengthwise stiffeners, were selected as examples and were analyzed during the removal of each layer. Moreover, a finite-element simulation of the milling process was conducted to make comparisons with the analytical results, which demonstrates similar stress distribution and springback values. The maximum stress variation and springback value appeared when the milling depth reached the initial neutral surface. When the plate thickness decreased, the errors between analytical results and FEM results increased, and the lengthwise-stiffened panel was less affected by errors than the crosswise-stiffened panel because of a larger moment of inertia. The effects of different milling thicknesses per layer, initial plate thickness, and bending radius were also analyzed. Moreover, the milling experiment was performed to make verification. The results suggest that the analytical method can predict the springback of the stiffened panel effectively. The proposed method can also be applied to other similar forming conditions.
Experimental study on shear capacity of circular concrete filled steel tubes
Congzhen Xiao,Shaohuai Cai,Tao Chen,Chunli Xu 국제구조공학회 2012 Steel and Composite Structures, An International J Vol.13 No.5
Concrete filled steel tube (CFST) structures have recently seen wide use in China, but studies of the shear problem of CFST are inadequate. This paper presents an experimental study on the shear capacity of circular concrete filled steel tube (CCFT) specimens with and without axial compression force. Shear capacity, ductility, and damage modes of CCFTs were investigated and compared. Test results revealed the following: 1) CCFTs with a small shear span ratio may fail in shear in a ductile manner; 2) Several factors including section size, material properties, shear span ratio, axial compression ratio, and confinement index affect the shear capacity of CCFTs. Based on test results and analysis, this paper proposes a design formula for the shear capacity of CCFTs.
Screening for Metastatic Osteosarcoma Biomarkers with a DNA Microarray
Diao, Chun-Yu,Guo, Hong-Bing,Ouyang, Yu-Rong,Zhang, Han-Cong,Liu, Li-Hong,Bu, Jie,Wang, Zhi-Hua,Xiao, Tao Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.4
Objective: The aim of this study was to screen for possible biomarkers of metastatic osteosarcoma (OS) using a DNA microarray. Methods: We downloaded the gene expression profile GSE49003 from Gene Expression Omnibus database, which included 6 gene chips from metastatic and 6 from non-metastatic OS patients. The R package was used to screen and identify differentially expressed genes (DEGs) between metastatic and non-metastatic OS patients. Then we compared the expression of DEGs in the two groups and sub-grouped into up-regulated and down-regulated, followed by functional enrichment analysis using the DAVID system. Subsequently, we constructed an miRNA-DEG regulatory network with the help of WebGestalt software. Results: A total of 323 DEGs, including 134 up-regulated and 189 down-regulated, were screened out. The up-regulated DEGs were enriched in 14 subcategories and most significantly in cytoskeleton organization, while the down-regulated DEGs were prevalent in 13 subcategories, especially wound healing. In addition, we identified two important miRNAs (miR-202 and miR-9) pivotal for OS metastasis, and their relevant genes, CALD1 and STX1A. Conclusions: MiR-202 and miR-9 are potential key factors affecting the metastasis of OS and CALD1 and STX1A may be possible targets beneficial for the treatment of metastatic OS. However, further experimental studies are needed to confirm our results.
Optical Planar Waveguides Fabricated by Using Carbon Ion Implantation in Terbium Gallium Garnet
Yue Wang,Xiao-Liang Shen,Rui-Lin Zheng,Peng Lv,Chun-Xiao Liu,Hai-Tao Guo 한국물리학회 2018 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.72 No.7
Optical planar waveguides in terbium-gallium-garnet (TGG) crystals are promising photonic devices, particularly for optical isolators and rotators. In this work, to the best of our knowledge, we report on the fabrication and the characterization of TGG waveguides for the first time. The fabrication procedure involved carbon ion implantation at an energy of 6.0 MeV and a fluence of 5.0×1014 ions/cm2. The effective refractive indices of the propagation modes in the carbonimplanted waveguide were measured by using the prism-coupling technique. The profile of the refractive index and the distribution of the near-field intensity were calculated by using the reflectivity calculation method and the finite-difference beam propagation method, respectively. The carbon-implanted TGG waveguide is considered to be a candidate for a magneto-optical photonic device.