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Chun-lei Zhang,Hui Wu,YanHong Wang,YuLong Zhao,XingTang Fang,CaiFa Chen,Hong Chen 한국유방암학회 2015 Journal of breast cancer Vol.18 No.3
Purpose: Circular RNAs (circRNAs), a novel class of RNAs, perform important functions in biological processes. However, the role of circRNAs in the mammary gland remains unknown. The present study is aimed at identifying and characterizing the circRNAs expressed in the mammary gland of lactating rats. Methods: Deep sequencing of RNase R-enriched rat lactating mammary gland samples was performed and circRNAs were predicted using a previously reported computational pipeline. Gene ontology terms of circRNA-producing genes were also analyzed. Results: A total of 6,824 and 4,523 circRNAs were identified from rat mammary glands at two different lactation stages. Numerous circRNAs were specifically expressed at different lactation stages, and only 1,314 circRNAs were detected at both lactation stages. The majority of the candidate circRNAs map to noncoding intronic and intergenic regions. The results demonstrate a circular preference or specificity of some genes. DAVID analysis revealed an enrichment of protein kinases and related proteins among the set of genes encoding circRNAs. Interestingly, four protein-coding genes (Rev3l, IGSF11, MAML2, and LPP) that also transcribe high levels of circRNAs have been reported to be involved in cancer. Conclusion: Our findings provide the basis for comparison between breast cancer profiles and for selecting representative circRNA candidates for future functional characterization in breast development and breast cancer.
The Closer Economic Partnership Arrangement between Macao and Mainland China and Its Implications
Chun Kwok LEI, Henry 한국무역학회 2014 한국무역학회 국제학술대회 Vol.2014 No.12
The Closer Economic Partnership Arrangement (CEPA) is a preferential trade agreement signed between Macao and China which opens the China market at zero tariffs for Macao Origin goods. It removes some restrictions to allow Macao service suppliers to establish in China. Besides, it introduces more friendly procedures to allow Chinese tourists to travel to Macao on an individual basis. Statistics suggest that the arrangement has brought about almost no contributions to the merchandising exports of Macao to China. This paper is then organized to empirically study Macaos exports with an intention to identify the major determinants, with an attempt to estimate the efficiency level of Macaos bilateral exports and the key contributors as well as to address the role of CEPA. The Stochastic Frontier Gravity model is applied and the regression result has proven our suspicious on the incapability of CEPA in boosting goods trade. When Macao-Hong Kong export is the most efficient flow, the efficiency score for Macao-China Export has been declining since the 90s and is just 21% in 2013. It implies that Macaos export to China is far from its full potential.
( Qiu Chun Li ),( Ya Chen Hu ),( Yin Fei Wu ),( Xiao Chun Wang ),( Xiao Lei Xie ),( Ming Xin Tao ),( Jun Lei Yin ),( Zhi Jie Lin ),( Yang Jiao ),( Li Juan Xu ),( Xinan Jiao ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.5
As Salmonella enterica serovar Pullorum remains a major economic problem for the poultry industries of countries with no efficient control measures, we presented a multidrug resistance strain S06004 (isolated from a clinically sick chicken in China in 2006) for genome sequencing. The genome comparison showed that the strain contained two prophages, the ST104 and prophage-4 (Fels2) of E. coli LF82, which were not detected in the only published genomes of S. Pullorum RKS5078 and CDC1983-67. In addition, the GyrA Ser83 point mutation, drugresistant genes, and many antibiotic pump systems that are present in S06004 may be contributing to the multidrug resistance of this strain.
Wan, Chun,Shen, Yong-Chun,Liu, Meng-Qi,Yang, Ting,Wang, Tao,Chen, Lei,Yi, Qun,Wen, Fu-Qiang Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9
The diagnosis of malignant mesothelioma (MM) remains a clinical challenge and the fluorescence in situ hybridization (FISH) assay has been reported to be one promising tool. The present meta-analysis aimed to establish the overall diagnostic accuracy of FISH for diagnosing MM. After a systematic review of English language studies, the sensitivity, specificity and other measures of accuracy of FISH in the diagnosis of MM were pooled using random-effects models. Summary receiver operating characteristic curves were applied to summarize overall test performance. Nine studies met our inclusion criteria, the pooled sensitivity and specificity for FISH for diagnosing MM being 0.72 (95% CI 0.67-0.76) and 1.00 (95% CI 0.98-1.00), respectively. The positive likelihood ratio was 34.5 (95% CI 14.5-82.10), the negative likelihood ratio was 0.24 (95% CI 0.16-0.36), and the diagnostic odds ratio was 204.9 (95% CI 76.8-546.6), the area under the curve being 0.99. Our data suggest that the FISH assay is likely to be a useful diagnostic tool for confirming MM. However, considering the limited studies and patients included, further large scale studies are needed to confirm these findings.
The Effect of Chinese University Students' Participation in Marshall Art on Academic Psychology
Xue, Chun-Lei,Song. Jeho 한국스포츠학회 2020 한국스포츠학회지 Vol.18 No.1
본 연구는 중국 대학생들의 마샬아트 참여가 학업심리스트레스에 미치는 영향을 규명하기 위해 수행 되었다. 이와 같은 연구목적 달성을 위한 연구 대상은 중국 산동성 위해시(山东省威海市)의 대학생들을 연구 대상으로 단순무작위 추출방법에 따라 600명 표본을 추출하였다. 본 연구는 대학생 스포츠상황 설문지, 심리스트레스설문지, 학업스트레스설 문지를 연구 수단으로 하였고, 문헌법, 조사법, 통계분석법 등 연구 방법을 사용하였으며, 마샬아트 참여 그룹과 일반 운동 그룹 간의 비교를 분석하고자 하였다. 그리고 마샬아트 참여가 대학생들의 신체적, 정신적, 건강증진 연구에 이론적 근거 와 대책을 마련하여 효과적인 방법으로 활용할 수 있는지에 대해서도 논의하였다. 조사 데이터에 대한 SPSS 20.0 분석을 통해 대학생의 심리적 스트레스의 주요 원천은 학업심리스트레스였으며, 무술 운동이 일반 체육 운동보다 대학생의 학업 긴장스트레스를 더욱 효율적으로 완화 한다는 결론을 얻었다. 이로써 본 연구는 마샬아트 참여가 심리적 스트레스 해소에 한층 더 발전시키기 위한 참고자료로 활용될 것으로 사료된다. This study was conducted to determine the effect of Chinese college students' participation in Marshall Art on academic psychologists. The subjects of this research were university students in Shandong Province, China, and 600 people were sampled according to the simple method of extracting no-action. This study conducted college student sports situation questionnaire, psychistress questionnaire, and academic stress questionnaire as a means of study, used research methods such as literature law, investigation method, statistical analysis method, and tried to analyze the comparison between the Marshall Art group and the general exercise group. They also discussed whether participation in Marshall Art can be used in effective ways by laying the rationale and countermeasures for the study of physical, mental and health promotion of university students. Through the SPS 20.0 analysis of survey data, the main source of psychological stress for college students was academic psychostrists, and the conclusion was that martial arts exercises relieve college students' academic tension stress more efficiently than ordinary physical exercises. The study is expected to serve as a reference for the further development of Marshall Art's participation in psychological stress relief.