Quantitative comparison of mRNA expression of glucosyltransferase(GTF) between xylitol-resistant(X^(R)) and xylitol-sensitive(X^(s)) mutans streptococci

Kim, Chong-Chul,Lee, Mi-Na,Kim, Young-Jae,Lee, Sung-Hoon 大韓小兒齒科學會 2006 大韓小兒齒科學會誌 Vol.33 No.1

Since the long-term exposure of mutans streptococci to xylitol is known to select for xylitol-resistant(X^(R)) natural mutants, the occurrence and survival of such X^(R) strains were performed in batch culture methods. The aim of the study was to compare the differentiation and quantification of mRNA expression of the gtf genes of X^(R) and X^(S) mutans streptococci. Using a real-time reverse-transcription polymerase chain reaction, the expression of each gtf was determined. In X^(R) strains, the relative levels of transcription of gtfB and gtfC were decreased while that of gtfD was increased, suggesting the presence of independent promoters. It also suggested that mutation related to production of glucosyltransferase occurred under the exposure of xylitol could explain the caries-preventive mechanisms of xylitol. 자일리톨에 장기간 노출된 mutans streptococci는 자일리톨에 내성이 발현되어 자일리톨 내성균주가 생성된다고 알려져 있다. 본 연구의 목적은 mutans streptococci에서 자일리톨 내성균주와 감성균주의 gtf 유전자 발현량을 각각의 유전자별로 정량적으로 분석하고 비교하는 것이다. 실시간 역전사 중합효소연쇄반응법을 이용하여 각각의 gtf 발현을 조사한 결과 gtfD는 증가한 반면. gtfB와 gtfC는 감소하였는데 이는 각 유전자의 독립된 조절기전이 존재함을 보여주는 것이다. 또한 자일리톨에 노출된 mutans streptococci에서의 glucosyltransferase와 연관된 유전자변형이 자일리톨의 치아우식증 예방효과의 작용기전 중 하나임을 알 수 있었다.

지역민방의 성과 분석 및 과제

남종훈 동신대학교 2005 論文集 Vol.15 No.-

Presently PSB was selected as a Gyungnam regional local private broadcasting operator. On the other hand, iTV is still looking for new owner. Although 10 years are passed from the first launching of local private broadcasting in Korea, there are still limit of localism and structural problem. Local private broadcasting started from both pursuing localism and making sure of competitiveness however it is not easy to execute those in Korean broadcasting situation. Until now, local private broadcasting is successful in stable management and ensuring profit but it is attributed to a role of transmission pipe of SBS. Now local private broadcasting should be changed to totally new broadcasting company pursuing creative local contents and new digital concept.

남도 문화 데이터베이스 설계 및 구현 : 남도 성씨를 중심으로

최훈,남종훈 한국정보전략학회 2001 한국정보전략학회지 Vol.4 No.1

This study shows how to build a cyber genealogy retrieval system which is focused on family name that is rooted from Chola-namdo's providence. Specially, this genealogy retrieval system focused on family name of Na which is originated from Naju city. This study, first of all, compared the results of previous studies and analyzed web sites that is related with genealogy retrieval system. This study also describes design of this system which added some more features under the multimedia environment. This system introduces agent that provides users to access information friendly. Also this system applies virtual tree algorithm which user can access his generation data as well as his parents, brothers and sisters, and parents information.

빈곤과 실업의 원인과 복지정책의 효과

안종범,김철희,전승훈 한국노동경제학회 2002 勞動經濟論集 Vol.25 No.1

본 연구는 빈곤과 실업의 결정요인과 상호관계를 살펴보고, 복지정책의 효과를 분석해 본다. 특히, 빈곤가구와 가구주의 특성, 가구주의 경제활동상태변화 및 이들 변수에 영향을 미치는 결정요인을 분석해 본다. probit 모형과 bivariate probit 모형을 이용한 실증분석 결과, 빈곤의 주된 원인으로 실업이 작용했고, 가구원수, 가구주의 연령 및 저학력 등도 원인으로 작용했음이 밝혀졌다. 사회보험 수급 등을 포함하는 복지정책은 이러한 실업이 빈곤에 미치는 영향을 축소시키는 요인으로 역할하고 있음이 추정 결과 나타났다. Using 3 years of panel data on nearly 3,507 households, the Korea Labor Income Panel Survey(KLIPS) data, the authors measure the determinants of poverty and unemployment, and the extents to which poverty influenced unemployment. The probit analysis of unemployment shows that unemployment probability is lower, when male, lower age and is higher, high-school and over junior college, work duration is over 3 years. The probit analysis of poverty shows that poverty probability is lower, when male, higher education level, longer career, specially unemployment and social insurance is determinants of increasing poverty. Bivariate probit model of unemployment and poverty also provides similar findings to those probit analysis and shows an evidence of the influence of unemployment on poverty along with the positive role of social welfare policy such that social welfare receipt reduces the impact of unemployment on poverty.

세계 상위 여자핸드볼 국가대표팀의 경기내용 분석

이종훈,이남수 서울産業大學校 2005 논문집 Vol.54 No.4

The purpose of this study was to analysis the matches between Korean national women's handball team and other teams in the Woman's Handball World Championship, in the period of Gyeongnam honorsville Cup, we analyzed game stactistics whick Korean national handball team to deal with other teams through the study of the opponents' offensive and defensive patterns improving the team's strength. In this study, the video tapes of the matches were analyzed two times in slow motion and still mode, and in the event of making errors, they were reanalyzed until they were perfectly analyzed. After the analyst diagramed each team's offensive and defensive patterns, we analyzed the radio of attempts of attacks to success rate of attacks, results are as follows: 1) Findings of the analysis on the success rate of attacks. Korean team's shot attempts reached 239, out of which it made 135 goals at the rate of 56.0%. Danish team, in slight difference, attempted 232 shots, out of which it made 138 gals at the rate of 58.0%. Ukrainian team attempted 198 shots and made 118 goals, rate of which was higher than the two despite fewer attempts. However, Chinese team showed the lowest success rate among the four teams, making 72 goals out of 183 shot attempts. Except for Chinese team, the rest teams turned out of to be nearly equal in offensive power. 2) Success rate of offensive by positions According to Ukrainian team's success rate of offense by positions, in orfer, right wing ranked the highest by 95.0%; pivot, 81%; left wing, 75.0%; right inner 41.0%; left inner,40%: center, 20.0%. Danish team's rate showed; right wing,92.0% marking the highest; pivot, 81%: left wing, 58.0%: right inner,54.0%: center,45.0%; left inner 31.0%, Chinese team's rate showed: right wing, 75.0% marking the highest: pivot. 59.0%: center,54.0%: left wing. 50.0%: left inner.36.0%: right inner, 31.0%. Korean ream's rate showed: pivot, 83.0% marking the highest: left wing, 78.0%: ringt inner, 67.0%: right wing. 57.0%: left inner. 48.0%: center. 29.0%. 3) Analysis of success rate by types of shooting. Analyzing success rate of shooting, Ukraina marks the highest (41.0%), then Denmark (34.0%), Korea (32.0%), and China (52.0%), Denmark (76.0%) tops success rate of shooting through fast-break, then Ukraina (63.0%), and China (61.0%), and Korea (41.0%). Korea definitely showed the highest success rate of free throw followed by China (57.0%), Denmark (53.0%), Ukraina (53.0%). 4) Analysis of GAA (goal-against-average) of goalkeeper (1) Ukraina's goalkeeper set a record of 38% GAA (180 attempts, 68 successes). Demark's goalkeeper set a record of 44% GAA (153 attempts, 68 successes). China's goalkeeper set a record of 37% GAA (174 attempts, 64 successes). Korea's goalkeeper set a record of 31% GAA (180 attempts, 56 successes). (2) As to each team's ranking for GAA, China ranked the first with 61% GAA, followed by Denmark (51%), Korea (47%), and Ukraina (42%). As to GAA on diving shots, Ukraina ranked the first with 38% GAA, followed by Denmark (35.0%), China (32.0%), and Korea (30.0%)As to GAA on fast-break goals, China ranked the first with 45.0% GAA, followed by China (35.0%), Ukraina (25.0%), and Korea (11.0%). As to GAA on free throws, Denmark rankd the first with 67.0% GAA, followed by Ukraina(38.0%), Korea(33.0%), and China (31.0%). As to GAA on 7-meter throw shots, both demark and Ukraina topped the ranking with 38.0% GAA, followed by China (23.0%) and Korea (0.0%).

림프구성 간질을 동반한 위선암종의 임상-병리학적 및 면역조직화학적 연구

김종만,김남훈,이중달 한양대학교 의과대학 1994 한양의대 학술지 Vol.14 No.1

Various clinicopathologic and immunologic parameters to determine the prognosis of gastric adenocarcinoma have been proposed. It has been reported that lymphocytes around tumor cells may play a role in determination of the prognosis. Among them gastric adenocarcinoma with lymphoid stroma(GALS), which is characterized by 1) a sparese population of small nests consisting of poorly differentiasted carcinoma cells widely separated by the intervening lymphocytic infiltration, and 2) the presence of a nondesmoplastic stroma infiltrated uniformly iwth abundant lymphocytes throughout the tumor frequently accompanied by lymph follicles, has been proven to show good prognosis. To evaluate the correlation between the pathologic patterns and immunologic expression of lymphocytes, the author reviewed clinical data and pathologic specimens from 13 cases of GALS. Immunohistochemical study on lymphocytes in GALS was performed. In comparison with ordinary gastric carcinomas GALS had the growth pattern of Borrmann type Ⅱ in 7 of 13(54%), and occured predominantly in the body. No correlation between the degree of lymphocytic infiltration and the metastases to the regional lymph nodes was noted. The less invasive tumors had a tendency to the more expanding in growth pattern, and more invasive tumor, more infiltrative. Immunohistochemical study revealed stromal lymphocytes of predominantly T-cell expression. T-cells were frequently seen in intimate contact with individual carcinoma cells. In contrast, B-cellls was sparsely scattered throughout apart from carcinoma cell nests.

의사소통중심 영어 발음 지도법

金種勳 한국영어교육연구학회 2000 영어교육연구 Vol.- No.21

The purpose of this paper is to present some classroom techniques available for teaching English pronunciation communicatively in order to develop communicative competence of English learners. The communicative approach to English pronunciation teaching that this study addresses is that pronunciation practice should take place beyond accurate production of isolated sounds or words and that must be linked to naturally understand the meanings of dialogs or conversation. This means that pronunciation teaching should not be restricted to drill the correct articulation of segmentals, but be extended to teach natural pronunciation of suprasegmentals. Two types of communicative activities, e.g. accuracy-focussed and fluency-focussed ones will be presented to teach English pronunciation within a framework of teaching pronunciation as communication.

영어과 수행평가 현장 활용 방법

김종훈 제주대학교 사범대학 2001 백록논총 Vol.3 No.1

The purpose of this paper is to study how to use performance assessment for English language learners in secondary schools in Korea. After examining genera1 types of performance assessment used in several courses, we will look at some types of English performance assessment, and then apply them to assessing the 4 skills of students who learn English in middle and high schools in Korea. There are numerous kinds of performance assessment used in classrooms today : essay test, oral test, discussion or debate, hands-on experiments, interview, oral and written reports, projects, constructed-response items, exhibitions, observation, self -assessment and portfolios. These types of assessment may be appplied to assessing the English language learners' skills. However, in the English classroom, several types of performance assessment should be devised to assess the learners' 4 skills, listening, speaking, reading and writing individually. They must include the ways of assessing the integrated skills for measuring communication abilities in real-life situations. To assess listening skills, teachers can ask students to listen and perform actions, to listen and draw, to listen and infer, to listen and answer, and to listen and transfer information. Teachers can assess their students' speaking skills, by asking them to produce oral reports, describing the pictures and retellng the stories. In order to test reading skills, teachers can ask students to read and summarize, read and guess, read and predict, read and infer, besides the cloze tests and C-test. Teachers can use the types of writing samples, editing and picture-cued description to assess the writing skills of the learners. For testing the integrated skills of the learners, oral interview, role play, simulation, filling information-gap and opinion-gap, debates and jigsaw are available.

남북한의 통일정책 비교분석

이종훈 동국대학교 대학원 1997 大學院硏究論集-東國大學校 大學院 Vol.27 No.-

Facing the 21th Century, one of the big issues on Korean Peninsula is the Reunification of divided Korea. Passed half century of the divided situation, the political situations of Korean Peninsula and the world politics are changed very much. Especially, political situations of the Northeast Asia are basically changing. A centre of the changing situation lies `two Koreas'. The Reunification of `two Koreas' is, after all, the problems of Korean people's existence. Therefore, on this essay, through the comparative analysis on the unification policy of `two Koreas', being pulled out the problems of unification policy, and is to expose the right orientation of the policy. Finally, the problems of reunification between `two Koreas' is the problems of the consciousness of `two Koreas'. Being the fight understanding of the Korean Peninsula's situation, `two Koreas' is to, prudently, resolve their essential problems.

성장기 아동에서의 기능성 전치부 개교의 치료증례

김종철,장기택,손동수,김주훈 大韓小兒齒科學會 1996 大韓小兒齒科學會誌 Vol.23 No.3

Anterior openbite is defined as the lack of contacts between the functional occluding teeth on vertical line at centric occlusion and classified into functional and skeletal anterior openbite based on its causes and characteristics. Anterior openbite causes masticatory, speech, and esthetic problems in the growing children and difficulties in diagnosis, treatment, and the prediction of its prognosis. We are reporting on the treatment of anterior openbite in the growing children and the results follow as : 1. In the growing children with anterior openbite, the overbite could be increased by the treatment according to its causes and characteristics. 2. The prognosis is not determined by the presence or severity of oral habit but the skeletal tendency of the patient.