Mechanical, thermal expansion, and flammability properties of co-extruded wood polymer composites with basalt fiber reinforced shells

Wu, Q.,Chi, K.,Wu, Y.,Lee, S. BUTTERWORTH - HEINEMANN 2014 MATERIALS AND DESIGN Vol.60 No.-

Basalt fiber (BF) filled high density polyethylene (HDPE) and co-extruded wood plastic composites (WPCs) with BF/HDPE composite shell were successfully prepared and their mechanical, morphological and thermal properties characterized. The BFs had an average diameter of 7μm with an organic surfactant surface coating, which was thermally decomposed at about 210<SUP>o</SUP>C. Incorporating BFs into HDPE matrix substantially enhanced flexural, tensile and dynamic modulus without causing a noticeable decrease in the tensile and impact strength of the composites. Micromechanical modeling of tensile properties for the BF/HDPE composites showed a good fit of the selected models to the experimental data. Compared to neat HDPE, BF/HDPE composites had reduced linear coefficient of thermal expansion (LCTE) values. The use of the pure HDPE and BF/HDPE layers over a WPC core greatly improved impact strength of core-shell structured composites. However, the relatively less-stiff HDPE shell with large LCTE values decreased the overall composite modulus and thermal stability. Both flexural and thermal expansion properties were enhanced with BF reinforced HDPE shells, leading to well-balanced properties of core-shell structured material. Cone calorimetry analysis indicated that flammability performance of core-shell structured composites was improved as the BF content increased in the shell layer.

A Study on APL Interpreter Using Ladder Mechanism

Wu, Chi-Su 울산대학교 1981 연구논문집 Vol.12 No.2

APL의 보완은 배열의 접근방식의 변환, 연산자의 재비치, 문법분석, APL의 숙어의 사용등에 의하여 행하여졌다. 본 논문은 배열의 접근방식을 위한 LADDER를 사용하여 APPLE-PASCAL을 이용한 변역기에 의한 A-Machine를 구성하는 방법의 제시이다. APL implementations have been carried out by transformations of array accessings, reordering of APL operators, syntactical analysis and using APL idioms. In this study, I propose that A-Machine code is generated by a translator which is written by APPLE-PASCAL using ladder mechanism.

Manufacturing of GaAs MMICs for Wireless Communications Applications

Wu-Jing Ho,Joe Liu,Hengchang Chou,Chan Shin Wu,Tsung Chi Tsai,Wei Der Chang,Frank Chou,Yu-Chi Wang 대한전자공학회 2006 Journal of semiconductor technology and science Vol.6 No.3

Two major processing technologies of GaAs HBT and pHEMT have been released in production at Win Semiconductors corp. to address the strong demands of power amplifiers and switches for both handset and WLAN communications markets. Excellent performance with low processing cost and die shrinkage features is reported from the manufactured MMICs. With the stringent tighter manufacturing quality control WIN has successfully become one of the major pure open foundry house to serve the communication industries. The advancing of both technologies to include E/D-pHEMTs and BiHEMTs likes for multifunctional integration of PA, LNA, switch and logics is also highlighted.

Unusual Exchange Bias Effects Induced in NiFe/Mn Thin Films via Ion-beam Bombardment: Superlattice vs. Nanocomposite

Chi-Hsin Liu,Chin Shueh,Tien-Chi Lan,Ko-Wei Lin,Wen-Chen Chen,Te-Ho Wu,R. D. Desautels,J. van Lierop 한국물리학회 2013 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.62 No.12

The interplay between interlayer coupling and exchange bias coupling in [NiFe/Mn] multilayerbasedthin films was investigated by using ion-beam bombardment during deposition to control theconfigurations from superlattice to nanocomposite or hybrid-structured thin films. Results showedthat well-defined interfaces in the superlattice [NiFe/Mn] thin film exhibited an interlayer couplingbehavior. In contrast, an enhanced coercivity was observed in the nanocomposite [NiFe-Mn] thinfilm. However, the hybrid [NiFe-Mn]/[NiFe/Mn] thin film with an intermixed NiFeMn alloyed filmcomponent gave rise to unusual positive exchange bias coupling.

The <i>bantam</i> microRNA acts through Numb to exert cell growth control and feedback regulation of Notch in tumor-forming stem cells in the <i>Drosophila</i> brain

Wu, Yen-Chi,Lee, Kyu-Sun,Song, Yan,Gehrke, Stephan,Lu, Bingwei Public Library of Science 2017 PLoS genetics Vol.13 No.5

<▼1><P>Notch (N) signaling is central to the self-renewal of neural stem cells (NSCs) and other tissue stem cells. Its deregulation compromises tissue homeostasis and contributes to tumorigenesis and other diseases. How N regulates stem cell behavior in health and disease is not well understood. Here we show that N regulates <I>bantam</I> (<I>ban</I>) microRNA to impact cell growth, a process key to NSC maintenance and particularly relied upon by tumor-forming cancer stem cells. Notch signaling directly regulates <I>ban</I> expression at the transcriptional level, and <I>ban</I> in turn feedback regulates N activity through negative regulation of the Notch inhibitor Numb. This feedback regulatory mechanism helps maintain the robustness of N signaling activity and NSC fate. Moreover, we show that a Numb-Myc axis mediates the effects of <I>ban</I> on nucleolar and cellular growth independently or downstream of N. Our results highlight intricate transcriptional as well as translational control mechanisms and feedback regulation in the N signaling network, with important implications for NSC biology and cancer biology.</P></▼1><▼2><P><B>Author summary</B></P><P>Stem cells are functional units in the development, maintenance, and regeneration of tissues in multicellular organisms. Defects in stem cell regulation can compromise tissue homeostasis and result in proliferative or degenerative diseases. Our understanding of the molecular and cellular mechanisms regulating the <I>in vivo</I> behavior of stem cells is still incomplete. The <I>Drosophila</I> central nervous system neural stem cells called neuroblasts have offered an excellent model system for uncovering key mechanisms and player involved in stem cell regulation. Previous genetic studies have uncovered the evolutionarily conserved Numb-N signaling pathway that regulates the self-renewal vs. differentiation choices of the cell fates of NSCs during their asymmetric division. Our understanding of how Numb-N signaling regulates NSC fate is still rudimentary. Recent studies have implicated the involvement of microRNAs in stem cell regulation in both mammalian and <I>Drosophila</I> systems. But the molecular mechanism and logic of miRNA action remain to be delineated. In this study we show that the <I>bantam</I> microRNA is a direct transcriptional target of the N signaling pathway, and that <I>bantam</I> feedback regulates N by negatively regulating the expression of Numb, an inhibitor of N. This feedback regulation of N helps maintain the robustness of NSC fate. We further show that <I>bantam</I> also impinges on a Numb-Myc axis of cell growth regulation, apparently in a N-independent manner. Together, our results highlight the importance of both transcriptional and translational control mechanisms in NSC regulation by the N signaling network. These findings have important implication for our understanding of the basic biology of NSCs and the therapeutic intervention of N-induced cancers.</P></▼2>

How to Map Phase Diagrams of Polymer Solutions - Microfluidics Marries Laser Light Scattering

Chi Wu 한국고분자학회 2017 한국고분자학회 학술대회 연구논문 초록집 Vol.42 No.2

Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps Sinensis in the Bronchoalveolar Lavage Fluids Cells

Kuo, Yuh-Chi,Wu, Chia-Lin,Tasi, Wei-Jern,Wang, Jir-Yenn,Chang, Shi-Chung,Lin, Ching-Yuang,Shiao, Ming-Shi 경희대학교 동서의학연구소 1999 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.1999 No.1

Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang₃,Ching-Yung Lin⁴,and Ming-Shi Shiao⁴¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan Yuh-Chi Kuo¹,Chia-Lin Wn¹,Wei-jern Tasi¹,Jir-Yenn Wang²,Shi-Chung Chang²,Ching-Yung Lin³,and Ming-Shi Shiao⁴.¹National Research Institute of Chinese Medicine, ²Department of Biology,Fu Jen University, ³Department of Chest, ⁴Department of Pediatrics, □De[art,amt of Medical Research and Education. Taipei Veterans General Hospital, Taipei, Taiwan. Blocking of Cell Proliferation, Cytokines Production and Genes Expression Following Administration of Cordyceps sinensis in the Bronchoalveolar Lavage Fluids Cells. Proceedings of international Symposium on East-West Medicine, Seoul. 44-64, 1999.-Cordyceps sinensis is a major parasitic fungus on larva of Lepidoptera. It is one of the well know fungi used in traditional Chinese medicine for treatment asthma, lung and kideney diseases. Many fungi belonging to the genus Cordyceps have been demonstrated to produce natural products with various biological activities. Reported biological activities of genus cordyceps include:(a)inhibition of DNA and RNA synthesis;(b)enhancement of cell differentiation;(c)restruction of cytoskeleton;(d)inhibition of protein kinase activity;(e)antitumor activity on bladder, colon, lung carcinoma as well as fibroblastoma;(f)inhibition of the infection and revers transciptase activity of human immunodeficiency virus type 1; and(g) inhibition of methylation of nucleic acid. Thus, it is suggested that the extracts of Cordyceps sp. Contain antitumor, antiviral, and many other biological activities. In our previous studies, we proved that C. sinensis contains the antitumor and immunomodulatory agents. In the present studies, effects of C. sinensis on bronchoalveolar lavage fluids(BAL)cells were demonstrated. The crude methanolic extracts of C. sinensis were fractionated into 15 fractions by silica gel column chromatography. Effects of various fraction on BAL cells proliferation and lipopolysaccharide(LPS) stimulated interleukin-1β(IL-8),platelet activating factor(PAF), interleukin-6(IL-6), tumor necrosis factor-α(TNF-α),and interleukin-8(IL-8) production on BAL cells were determined. The result indicated that the CS-19-22 fraction suppressed BAL cells proliferation activated by LPS. The median inhibitory concentration(IC50) was 6㎍/ml. The CS-19-22 fraction also decreased IL-1β,PAF,IL-6, TNF-αand IL-8 production.The results of revers transcription-polymerase chain reaction(RT-PCR) demonstrated that the CS-19-22 fraction did not affect IL-1β,PAF,IL-6, TNF-α,and IL-8 mRNAs expression in BAL cells activated by LPS. By contrast, it inhibited the IL-10 mRNA expression but enhanced IFN-γand IL-12 mRNAs expression in activated BAL cells. Moreover, the CS-19-22 fraction blocked PAF-induced platelet aggregation. It is unlikely that cytotoxicity was involved. Because no cell deths were observable. We hypothesize that inhibitory mechanisms of CS-19-22 on BAL cells proliferation may be related to the impairments of gene expression and production of cytokines in BAL cells. The explanation of C. sinensis antiasthma function may involved the following(1)C.sinenesis contained immunomodulatory agents that stimulated IFN-γand IL-12 expression in TH1cells.(2)Enhanced secretion of IFN-γand IL-12 will inhibit the Tγcells immune responses Ex. Decreasing of IL-6 and IL-10 production.(3) The impairments of cytokines production in TH2 cells suppressed th BAL cells proliferation then more cytokines production Ex.IL-1β,PAF,IL-6,TNF-αand IL-8 in activated BAL cells were decreased. (4)The suppression of TH2cells immune responses will inhibit the growth and differentiation of B cells then IgE production will be decreased. (5)Reduced production of IgE will decreased asthma attack occurring in individuals. However, the results of the present study suggested that C. sinensis may also have acted to treat asthma in part by inhibiting BAL cells proliferation and cytokine gene expression and production. Future, experiments with treatment of animals with asthma with C. sinensis will be necessary to defined whether C. sinensis can reduce asthma injury. Plans are underway for the isolation of pure principal growth inhibitors and their mechanisms of action are subjected for further study.

외국의 최신 문헌 초록 : Lactic Acid Dehydrogenase 의 임상적 고찰

Chi Ping Wu,Juei Low Sung 대한내과학회 1962 대한내과학회지 Vol.5 No.9

Effect of weight reduction on the severity of lower urinary tract symptoms in obese male patients with benign prostatic hyperplasia: A randomized controlled trial

Chi-Hang Yee,Wing-Yee So,Sidney KH Yip,Edwin Wu,Phyllis Yau,Chi-Fai Ng 대한비뇨의학회 2015 Investigative and Clinical Urology Vol.56 No.3

Purpose: We assessed whether weight reduction is an effective intervention for the management of lower urinary tract symptoms (LUTS) and investigated the relationship between obesity and LUTS. Materials and Methods: This was a prospective randomized controlled trial that enrolled obese men older than 50 years with LUTS. The study period was 52 weeks. All patients received standardized alpha-adrenergic blocker therapy for the treatment of benign prostatic hyperplasia (BPH) during the run-in period. Patients were randomized to receive either a standardized prerecorded video program on the general principle of weight reduction or a comprehensive weight reduction program. Patients were assessed at different time points with symptom assessment, uroflowmetry, transrectal ultrasound, and metabolic assessment. Results: Sixty-five patients were allocated to each study arm. After the study period, no significant difference in weight reduction was found between the two arms. When the pre- and postintervention parameters were compared, none were statistically different between the 2 arms, namely nocturia, International Prostate Symptom Score, quality of life assessment, and uroflowmetry parameters. When the whole study population was taken as a single cohort, these parameters were also not significantly different between the group with a body mass index of 25 to <30 kg/m2 and the group with a BMI of 30 to 35 kg/m2. Conclusions: We found no association between obesity and LUTS. This could have been due to the less marked weight difference in our cohort. Whereas weight reduction may be an effective measure to improve LUTS, the implementation of a successful program remains a challenge.

The perturbation for the Drazin inverse

Chi-Ye Wu,Ting-Zhu Huang 한국전산응용수학회 2009 Journal of applied mathematics & informatics Vol.27 No.1

A representation for the Drazin inverse of an arbitrary square matrix in terms of the eigenprojection was established by Rothblum [SIAM J. Appl. Math., 31(1976):646-648]. In this paper perturbation results based on the representation for the Darzin inverse AD = (A − X)−1(I − X) are developed. Norm estimates of ∥(A+E)D−AD∥2/∥AD∥2 and ∥(A+E)#− AD∥2/∥AD∥2 are derived when ∥E∥2 is small. A representation for the Drazin inverse of an arbitrary square matrix in terms of the eigenprojection was established by Rothblum [SIAM J. Appl. Math., 31(1976):646-648]. In this paper perturbation results based on the representation for the Darzin inverse AD = (A − X)−1(I − X) are developed. Norm estimates of ∥(A+E)D−AD∥2/∥AD∥2 and ∥(A+E)#− AD∥2/∥AD∥2 are derived when ∥E∥2 is small.