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      • Study on Effect of Massage Technique based on Chaos Theory

        Ping Feng,Xiao-li Wang,Chao Zhang,Wei Sun,Dai-min Chen 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.12

        According to the mechanism of EMG signal, we know that the sacrificial electrical signal is with weak signal, low frequency, alternating, nonlinear and non-stationary characteristics. Nonlinear analysis includes higher order spectral analysis and fractal and chaos analysis.Chaos theory is one of the main parts of nonlinear science, and the electrical signal of the surface has a strong randomness, so we could consider the nonlinear analysis of EMG signals from the perspective of chaos. We mainly studied on the nonlinear analysis algorithm of EMG signal detailedly in this paper. Experiments show that,according to the quantitative analysis of several important parameters of rolling massage with chaos theory, we can measure objectively the action situation of related muscle groups in the operation course, then guide the professional massage students to understand the norms of operation in training of operation and help to lead their manipulation to the best power structure.

      • Risk Factors for Surgical Site Infections after Liver Resec-tion (A Multivariate Analysis of 6,132 Patients)

        ( Li-yang Sun ),( Jiong-jie Yu ),( Ju-dong Li ),( Xin-fei Xu ),( Jia-he Wang ),( Bing Quan ),( Wen-tao Yan ),( Feng Shen ),( Chao Li ),( Lei Liang ),( Tian Yang ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

        Aims: Surgical site infection (SSI) is a common postoperative complication and associated with an increased morbidity, hospital stay, and overall cost. The aim of the present study was to identify risk factors for SSIs after hepatic resection based on a large single-center cohort. Methods: A retrospective study was conducted of 6,132 patients who underwent liver resection without concomitant biliary reconstruction or gastrointestinal procedures between 2014 and 2016 at the largest hepatic center in China. The occurrences of SSI, classified as incisional SSI and organ/space SSI within 30 days after operation were investigated. Patient- and surgical-related risk variables were collected using standardized data collection form. A likelihood ratio forward regression model was used to assess the independent association of risk factors with SSI. Results: SSI developed in 587 patients (9.6%), including superficial/deep incisional SSI in 357 patients (5.8 %), and organ/ space SSI in 304 patients (5.0 %). Multivariate logistic regression analysis showed that obesity, diabetes mellitus, ASA score ≥ 2, liver cirrhosis, re-hepatectomy, hepatoliathiasis, and intraoperative blood transfusion were independent risk factors of overall SSI. However, incisional and organ/space SSI differed from each other with respect to risk factors. Among a variety of risk factors, hepatolithiasis, liver cirrhosis, and intraoperative blood transfusion were consistently associated with both incisional and organ/space SSI. Conclusions: SSI is a common complication after liver resection, and more caution should be taken in patients with hepatolithiasis or liver cirrhosis. Prevention strategies focusing on factors associated with SSI is necessary in order to reduce SSI after liver resection.

      • KCI등재

        Bearing Habits of Acer truncatum and the Relationship Between Its Branch Characteristics and Fruiting Performance

        Chao Li,Xiaoling Liu,Yi Feng,Tian Bao,Changqi Ye,Dailong Li,Shuchai Su 한국원예학회 2021 원예과학기술지 Vol.39 No.2

        In recent years, seeds of the Shantung maple have attracted attention for their economic and medicinal value due to the high nervonic acid content in their seed oil, which has a curative effect on some demyelinating diseases. However, few studies have investigated its fruiting habits and branch characteristics; therefore, the purpose of this research was to investigate the fruit bearing habits of A. truncatum and analyze the relationship between its branch characteristics and fruiting performance to provide a basis for management. The branch structure, flower-bearing position, and continuous fruiting ability of 200 A. truncatum individuals were recorded from 2014–2017. The results showed that parent and bearing shoots of A. truncatum were usually short (less than 10 cm) with fruit developed by terminal mixed buds of the parent shoot. A. truncatum can form a Y-shaped branch group with continuous fruiting ability for many years via a lateral shoot of the bearing shoot. The position and slenderness of the parent shoot had a significant influence on the yield of the bearing shoot and seed weight, length, and thickness. The top and basal diameters of the parent shoot had a significant influence on the yield of the bearing shoot. Group comparison results showed that the most effective and convenient method for the selection of parent shoots with high fruiting performance was based on the position and top diameter of the parent shoots, among which the parent shoots with a top diameter thicker than 3.08 mm developed by a lateral bud in a vegetative branch had greater yield, number of fruit, and seed weight.

      • SCIESCOPUSKCI등재

        Characterization of the Methylation Status of Pax7 and Myogenic Regulator Factors in Cell Myogenic Differentiation

        Chao, Zhe,Zheng, Xin-Li,Sun, Rui-Ping,Liu, Hai-Long,Huang, Li-Li,Cao, Zong-Xi,Deng, Chang-Yan,Wang, Feng Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.7

        Epigenetic processes in the development of skeletal muscle have been appreciated for over a decade. DNA methylation is a major epigenetic modification important for regulating gene expression and suppressing spurious transcription. Up to now, the importance of epigenetic marks in the regulation of Pax7 and myogenic regulatory factors (MRFs) expression is far less explored. In the present study, semi-quantitative the real-time polymerase chain reaction (RT-PCR) analyses showed MyoD and Myf5 were expressed in activated and quiescent C2C12 cells. MyoG was expressed in a later stage of myogenesis. Pax7 was weakly expressed in differentiated C2C12 cells. To further understand the regulation of expression of these genes, the DNA methylation status of Pax7, MyoD, and Myf5 was determined by bisulfite sequencing PCR. During the C2C12 myoblasts fusion process, the changes of promoter and exon 1 methylation of Pax7, MyoD, and Myf5 genes were observed. In addition, an inverse relationship of low methylation and high expression was found. These results suggest that DNA methylation may be an important mechanism regulating Pax7 and MRFs transcription in cell myogenic differentiation.

      • SCIESCOPUSKCI등재

        Prevalence and Genetic Characterization of Toxoplasma gondii in Pet Dogs in Central China

        Wei-Feng Qian,Wen-Chao Yan,Tian-Qi Wang,Kai Zhai,Li-Fang Han,Chao-Chao Lv 대한기생충학열대의학회 2015 The Korean Journal of Parasitology Vol.53 No.1

        The prevalence and genotype of Toxoplasma gondii infection in dogs in Henan Province, Central China was investigated. A total of 125 blood samples were collected from pet dogs during April to June 2013, and all samples were examined by indirect hemagglutination antibody test (IHA) and nested PCR. The overall T. gondii prevalence in pet dogs was 24.0% (30/125), with 20.8% (26/125) in IHA and 10.4% (13/125) in PCR, respectively. No statistical associations were found between animal gender and age and the prevalence of T. gondii infection. Thirteen positive DNA samples were genotyped using 11 PCR-RFLP markers, including SAG1, (3’+5’) SAG2, alt.SAG2, SAG3, BTUB, GRA6, c22-8, c29- 2, L358, PK1, and Apico. Of these, only 2 samples were genotyped with complete data for all loci, and a novel genotype (type III at SAG3 and GRA6 loci, and type I at other loci) was identified. This is the first report of genetic characterization of T. gondii infection in dogs in China.

      • Use of Acupressure to Improve Gastrointestinal Motility in Women after Trans-abdominal Hysterectomy

        Chen, Li-Li,Hsu, Sheng-Feng,Wang, Min-Hung,Chen, Chao-Ling,Lai, Jim-Shoung 경희대학교 2001 INTERNATIONAL SYMPOSIUM ON EAST-WEST MEDICINE Vol.2001 No.1

        Objective : To evaluate the effectiveness of acupressure on the gastrointestinal motility (GI) in women after trans-abdominal hysterectomy(TAH). Methods : Forty-one women undergoing trans-abdominal hysterectomy were recruited and randomly assigned to two groups. Twenty-one patients were assigned to the experimental group while remaining 20 patients were assigned as controls. A single blinded test was used for this study. Patients were not informed as to the tripe of treatment they would receive. The experimental group received twice daily acupressure for 3 minutes at three meridian points, Neiguan(PC-6), Zusanli(ST-36) and Sanyinjiao(SP-6), beginning 4 hours after surgery and continuing for 3 days. Control group received 3 minutes acupressure on non-meridian points on the tibia or radial bone surface approximately 3 to 4 cm from the corresponding three meridian points. Acupressure was performed twice a day, one at 10 Am and another at 2 Pm. GI contractions was measured by stethoscope prior to and after afternoon acupressure during 2- minute observational period. Results : Results show that acupressure of these three meridian points significantly (p<0.05) increased GI motility in the experimental groups, but not in the control group (p>0.05). Conclusions : Results showed that non-invasive acupressure of these meridian points could significantly improve the GI motility and could be incorporated into the technical curriculum and clinical education program of nursing schools. Family members of the patient could be taught to continue this procedure at home to enhance GI motility in patients undergoing trans-abdominal hysterectomy.

      • KCI등재

        Chaotic dynamic characteristics of pressure fluctuation signals in hydro-turbine

        Wen-Tao Su,Xiao-Bin Li,Chao-Feng Lan,Shi An,Jiansheng Wang,Feng-Chen Li 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.11

        The pressure fluctuation characteristics in a Francis hydro-turbine running at partial flow conditions were studied based on the chaotic dynamic methods. Firstly, the experimental data of pressure fluctuations in the draft tube at various flow conditions was de-noised using lifting wavelet transformation, then, for the de-noised signals, their spectrum distribution on the frequency domain, the energy variation and the energy partition accounting for the total energy was calculated. Hereby, for the flow conditions ranging from no cavitation to severe cavitation, the chaos dynamic features of fluctuation signals were analyzed, including the temporal-frequency distribution, phase trajectory, Lyapunov exponent and Poincaré map etc. It is revealed that, the main energy of pressure fluctuations in the draft tube locates at low-frequency region. As the cavitation grows, the amplitude of power spectrum at frequency domain becomes larger. For all the flow conditions, all the maximal Lyapunov exponents are larger than zero, and they increase with the cavitation level. Therefore, it is believed that there indeed exist the chaotic attractors in the pressure fluctuation signals for a hydro-turbine.

      • Is Surgical Resection Justified for Hepatocellular Carcinoma with Portal Vein Tumor Thrombus? (A Systematic Review and Meta-Analysis)

        ( Liang Lei ),( Xin-fei Xu ),( Jiong-jie Yu ),( Ju-dong Li ),( Zhen-li Li ),( Jun Han ),( Han Zhang ),( Hao Xing ),( Han Wu ),( Ming-da Wang ),( Chao Li ),( Zheng Wang ),( Feng Shen ),( Meng-chao Wu ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

        Aims: The prognosis of hepatocellular carcinoma (HCC) with portal vein tumor thrombus (PVTT) is very poor. According to the BCLC treatment recommendations, sorafenib or other palliative treatment (PT) is recommended as the first-line therapy when it happens. In real world, however, a significant number of selected patients with HCC and PVTT suffered from surgical resection (SR). Methods: PubMed, Embase, Medline and Cochrane library were searched for studies comparing SR with PT (including TACE, sorafenib, etc.) for HCC with PVTT, which were published before September 2017. Results: 4,810 patients from 7 studies were enrolled in this meta-analysis, which divided into the SR group (n = 2,344) and the PT group (n = 2476). When compared with the PT group, the pooled hazard ratio (HR) for the 1, 3 and 5-year OS rates of the SR group were 0.56 (95% CI 0.52-0.60, P=0.03), 0.56 (95% CI 0.53-0.59, P<0.001) and 0.55 (95% CI 0.54-0.57, P<0.001). For subgroup analysis, when compared with the mere TACE group, the pooled HR for the 1, 3 and 5-year OS rates of the SR group were 0.54 (95% CI 0.43-0.67, P=0.81), 0.75 (95% CI 0.65-0.87, P=0.25) and 0.76 (95% CI 0.67-0.88, P=0.25). Conclusions: This meta-analysis demonstrated SR had better OS than TACE or other palliative therapy for HCC with PVTT. SR may be suitable as the first-line treatment for selected patients with resectable HCC and removable PVTT.

      • KCI등재

        ACOX1 destabilizes p73 to suppress intrinsic apoptosis pathway and regulates sensitivity to doxorubicin in lymphoma cells

        ( Fei-meng Zheng ),( Wang-bing Chen ),( Tao Qin ),( Li-na Lv ),( Bi Feng ),( Yan-ling Lu ),( Zuo-quan Li ),( Xiao-chao Wang ),( Li-ju Tao ),( Hong-wen Li ),( Shu-you Li ) 생화학분자생물학회(구 한국생화학분자생물학회) 2019 BMB Reports Vol.52 No.9

        Lymphoma is one of the most curable types of cancer. However, drug resistance is the main challenge faced in lymphoma treatment. Peroxisomal acyl-CoA oxidase 1 (ACOX1) is the rate-limiting enzyme in fatty acid β-oxidation. Deregulation of ACOX1 has been linked to peroxisomal disorders and carcinogenesis in the liver. Currently, there is no information about the function of ACOX1 in lymphoma. In this study, we found that upregulation of ACOX1 promoted proliferation in lymphoma cells, while downregulation of ACOX1 inhibited proliferation and induced apoptosis. Additionally, overexpression of ACOX1 increased resistance to doxorubicin, while suppression of ACOX1 expression markedly potentiated doxorubicin-induced apoptosis. Interestingly, downregulation of ACOX1 promoted mitochondrial location of Bad, reduced mitochondrial membrane potential and provoked apoptosis by activating caspase-9 and caspase-3 related apoptotic pathway. Overexpression of ACOX1 alleviated doxorubicin-induced activation of caspase-9 and caspase-3 and decrease of mitochondrial membrane potential. Importantly, downregulation of ACOX1 increased p73, but not p53, expression. p73 expression was critical for apoptosis induction induced by ACOX1 downregulation. Also, overexpression of ACOX1 significantly reduced stability of p73 protein thereby reducing p73 expression. Thus, our study indicated that suppression of ACOX1 could be a novel and effective approach for treatment of lymphoma. [BMB Reports 2019; 52(9): 566-571]

      • SCISCIESCOPUS

        Immobilization of Coacervate Microcapsules in Multilayer Sodium Alginate Beads for Efficient Oral Anticancer Drug Delivery

        Feng, Chao,Song, Ruixi,Sun, Guohui,Kong, Ming,Bao, Zixian,Li, Yang,Cheng, Xiaojie,Cha, Dongsu,Park, Hyunjin,Chen, Xiguang American Chemical Society 2014 Biomacromolecules Vol.15 No.3

        <P>We have designed and evaluated coacervate microcapsules-immobilized multilayer sodium alginate beads (CMs-M-ALG-Beads) for oral drug delivery. The CMs-M-ALG-Beads were prepared by immobilization of doxorubicin hydrochloride (DOX) loaded chitosan/carboxymethyl coacervate microcapsules (DOX:CS/CMCS-CMs) in the core and layers of the multilayer sodium alginate beads. The obtained CMs-M-ALG-beads exhibited layer-by-layer structure and rough surface with many nanoscale particles. The swelling characteristic and drug release results indicated that 4-layer CMs-M-ALG-Beads possessed favorable gastric acid tolerance (the swelling rate <5%, the cumulative drug release rate <3.8%). In small intestine, the intact DOX:CS/CMCS-CMs were able to rapidly release from CMs-M-ALG-Beads with the dissolution of ALG matrix. Ex vivo intestinal mucoadhesive and permeation showed that CMs-M-ALG-Beads exhibited continued growth for <I>P</I><SUB>app</SUB> values of DOX, which was 1.07–1.15 folds and 1.28–1.38 folds higher than DOX:CS:CMCS-CMs in rat jejunum and ileum, respectively, demonstrating that CMs-M-ALG-Beads were able to enhance the absorption of DOX by controlled releasing DOX:CS/CMCS-CMs and prolonging the contact time between the DOX:CS/CMCS-CMs and small intestinal mucosa.</P><P><B>Graphic Abstract</B> <IMG SRC='http://pubs.acs.org/appl/literatum/publisher/achs/journals/content/bomaf6/2014/bomaf6.2014.15.issue-3/bm401890x/production/images/medium/bm-2013-01890x_0010.gif'></P><P><A href='http://pubs.acs.org/doi/suppl/10.1021/bm401890x'>ACS Electronic Supporting Info</A></P>

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