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Carlin, J.A.,Lee, G.h.,Dellapenna, T.M.,Laverty, P. Academic Press in association with the Estuarine a 2016 Estuarine, coastal and shelf science Vol.172 No.-
<P>Meteorological frontal passages are recognized as important mechanisms for remobilizing sediment in estuaries along the northern Gulf of Mexico, but few studies have addressed factors beyond wind speed as a predictor for resuspension. To better understand resuspension mechanisms during these events, this study investigated the effects of wind, waves, and currents on suspended sediment concentration near the seabed during frontal passages in the shallow, micro-tidal West Galveston Bay located along the Texas coast. In late January and early February 2013, two multi-day deployments of instrumented pods (an acoustic Doppler velocimeter, and an acoustic wave and current profiler) were conducted to capture two separate frontal passages. The results indicate that the bed shear stress under the combined effect of waves and currents showed a much stronger relationship to sediment resuspension (R-2 = 0.90) than wind stress alone (R-2 = 0.55), or currents alone (R-2 = 0.72). Increases in the bed shear stress due to the combined effects of waves and currents resulted from increased wave height, which is strongly related to fetch within the bay. Therefore, understanding fetch-limited wave heights as a function of wind speed and direction, in conjunction with basin geometry, may be a better way to predict sediment resuspension during meteorological frontal passages in the shallow bays of the northern Gulf of Mexico. (C) 2016 Elsevier Ltd. All rights reserved.</P>
Surface Modification of Wool Fabric with POSS® Nanomaterial
Carline Bakker,Arun Ghosh,Surinder Tandon,Steve Ranford 한국섬유공학회 2018 Fibers and polymers Vol.19 No.10
Wool fabrics, without any surface treatment, can undergo undesirable and irreversible structural changes of wool fiber during washing under heat and mechanical agitation, leading to high shrinkage of wool garments. The traditional method based on polyamide resin can prevent felting and/or shrinkage of wool textiles, but adversely affect the surface hydrophobicity. In the present study, a treatment solution was developed based on TriSilanolIsooctyl POSS® and 3- mercaptopropyl trimethoxysilane, which created wool surface with increased hydrophobicity and highly resistant to shrinkage or felting, as measured after 3×5A wash cycles (equivalent to 24 domestic washes). After the treatment, the wool fabric appeared to be superhydrophobic with a water contact angle of above 150 o, compared to the untreated fabric. The treatment has marginal effect on mechanical performance as observed in tensile properties. Scanning electron microscopic images revealed a coating of POSS® on the wool surface. The dyeing of untreated and treated fabrics appeared to be uniform to the naked eye, though spectrophotometric analysis indicated a difference in the extent of dyeing performance. This research showed that POSS®-based treatment is a potentially effective approach for developing shrink-resistant wool textiles with enhanced surface hydrophobicity, in contrast to traditional chlorine/polyamide resin treatment.
Pasireotide treatment for severe congenital hyperinsulinism due to a homozygous ABCC8 mutation
Mooij Christiaan F.,Tacke Carline E.,van Albada Mirjam E.,Barthlen Winfried,Bikker Hennie,Mohnike Klaus,Oomen Matthijs W.N.,van Trotsenburg A.S. Paul,Zwaveling-Soonawala Nitash 대한소아내분비학회 2021 Annals of Pediatirc Endocrinology & Metabolism Vol.26 No.4
ABCC8 and KCJN11 mutations cause the most severe diazoxide-resistant forms of congenital hyperinsulinism (CHI). Somatostatin analogues are considered as secondline treatment in diazoxide-unresponsive cases. Current treatment protocols include the first-generation somatostatin analogue octreotide, although pasireotide, a second-generation somatostatin analogue, might be more effective in reducing insulin secretion. Herein we report the first off-label use of pasireotide in a boy with a severe therapy-resistant form of CHI due to a homozygous ABCC8 mutation. After partial pancreatectomy, hyperinsulinism persisted; in an attempt to prevent further surgery, off-label treatment with pasireotide was initiated. Short-acting pasireotide treatment caused high blood glucose level shortly after injection. Long-acting pasireotide treatment resulted in more stable glycemic control. No side effects (e.g., central adrenal insufficiency) were noticed during a 2-month treatment period. Because of recurrent hypoglycemia despite a rather high carbohydrate intake, the boy underwent near-total pancreatectomy at the age of 11 months. In conclusion, pasireotide treatment slightly improved glycemic control without side effects in a boy with severe CHI. However, the effect of pasireotide was not sufficient to prevent near-total pancreatectomy in this case of severe CHI.
Maturation of arteriovenous fistula: Analysis of key factors
Muhammad A. Siddiqui,Suhel Ashraff,Thomas Carline 대한신장학회 2017 Kidney Research and Clinical Practice Vol.36 No.4
The growing proportion of individuals suffering from chronic kidney disease has considerable repercussions for both kidney specialists and primary care. Progressive and permanent renal failure is most frequently treated with hemodialysis. The efficiency of hemodialysis treatment relies on the functional status of vascular access. Determining the type of vascular access has prime significance for maximizing successful maturation of a fistula and avoiding surgical revision. Despite the frequency of arteriovenous fistula procedures, there are no consistent criteria applied before creation of arteriovenous fistulae. Increased prevalence and use of arteriovenous fistulae would result if there were reliable criteria to assess which arteriovenous fistulae are more likely to reach maturity without additional procedures. Published studies assessing the predictive markers of fistula maturation vary to a great extent with regard to definitions, design, study size, patient sample, and clinical factors. As a result, surgeons and specialists must decide which possible risk factors are most likely to occur, as well as which parameters to employ when evaluating the success rate of fistula development in patients awaiting the creation of permanent access. The purpose of this literature review is to discuss the role of patient factors and blood markers in the development of arteriovenous fistulae.