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한국인 갑상선 유두암에서 ret 암 전구 유전자 재배열 ( ret/PTC) 의 발현빈도 및 그 임상적 의의
이명식,김성훈,양정현,김광원,민용기,김동준,정재훈,김경아,김병준,이문규,남석진,함종렬,이회정 대한내분비학회 1999 Endocrinology and metabolism Vol.14 No.1
Background: The prevalence of ret/PTC rearrangement in papillary thyroid carcinomas has been found to have wide variance in different populations. Recent studies, however, have been reporting no significant geographical difference between Asian and Western countries. In addition, there are some arguments about the correlation of ret/PTC expression with clinical aggressiveness. We have performed this study in order to examine the prevalence of ret/PTC-1, -2 and -3 rearrangements in korean papillary throid carcinomas and to ascertain its clinical relevance. Methods: Fourteen thyroid tumors histologically confirmed to be papillary carcinomas were included in this study. To find rearrangements, we adopted RT-PCR and automated direct sequencing. Initial and follow-up clinical data were obtained form the patients medical records. The plasmid containing ret/PTC-2, and 3 was kindly provided by Dr. Ahn (Ulsan University, Seoul Choonang Hospital). Results: We identified one tumors containing ret/PTC-1(1/14, 7.1%), and two containing ret/PTC-2 (2/14, 14.2%), and could not find ret/PTC-3 rearrangement in other patients (0/11). There was no significant correlation of ret/PTC with clinical aggressiveness. Conclusion: We found that the prevalence of ret/PTC rearrangement (3/14, 21.4%) in papillary thyroid carcinomas from Korea was similar to those recently reported in other nations. ret/PTC rearrangement may not affect biological behaviors of papillary thyroid carcinomas (J Kor Soc Endocrinol 14:532, 1999).
칼시토닌 및 소마토스타틴 분비 췌장 소도세포 종양으로 인한 당뇨병 1예
이명식,김성훈,김광원,민용기,김동준,정재훈,김경아,김병준,이문규,함종렬,이회정,오영륜 대한내분비학회 1999 Endocrinology and metabolism Vol.14 No.2
A case of 39-year-old diabetic patient with a calcitonin and somatostatin secreting pancreatic islet tumor is presented. He had suffered from chronic diarrhea and dyspepsia for 10 years and was diagnosed with diabetes 2 years ago. Abdominal CT revealed a huge abdominal mass which was considered as a neuroendocrine tumor after US-guided needle biopsy. A distal pancreatectomy and splenectomy were performed. Histologically, tumor cells, amanged in solid sheets, showed small nuclei without significant atypia and granular eosinophilic cytoplasm. Tumor cells showed strong immunoreacitivity for calcitonin and somatostatin. The serum clacitonin was markedly elevated (268.7 pmol/L, normal range; 0.9-7.6 pmol/L). After resection of the tumor, diarrhea and dyspepsia diappeared, and oral glucose tolerance test showed normal glucose tolerance with normalization of calcitonin. (J Kor Soc Endocrinol 14:425-431, 1999)
규불화염계 혼화제의 유효농도가 시멘트 모르타르의 수밀성 및 수화온도에 미치는 영향
이정열,김재온,남재현,박용순,이병기,김도수,한승구 대한건축학회 2004 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.24 No.1(구조계)
In this study, effects of fluosilicate salt(MSiF_(6), M : Zn, Mg) based chemical admixture, prepared using fluosilicic acid(H₂SiF_(6)) produced as industrial waste in dometic, on the watertightness and hydration temperature of cement mortar were evaluated. As a factor, effective concentration(1~10%) of fluosilicate salt was selected and applied 1% based on cement weight to cement mortar respectively. Among these concentration, addition of fluosilicate salts in the range 4~8% improved watertightness and hardened properties of cement mortar. Moreover it confirmed newly odd phenomenon that hydration temperature of cement mortar added equivalent concentration lowered than non-added specimen in spite of improving in the compressive strength.
류상열 ( Sang Ryol Ryu ),박지영 ( Ji Young Park ),류용석 ( Yong Suc Ryu ),유연화 ( Yeon Hwa Yu ),양동진 ( Dong Jin Yang ),이병훈 ( Byoung Hoon Lee ),김상훈 ( Sang Hoon Kim ),이재형 ( Jae Hyung Lee ),우정주 ( Jeong Joo Woo ) 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.67 No.2
Lipomas are common soft tissue tumors that are located in the body tissues containing adipose tissues. However, lipomas arising from the walls of a vein are very rare. Intravascular lipomas have been described most commonly in association with the inferior vena cava. Intravascualar lipomas involving the subclavian vein are rare. We are reporting a case of an asymptomatic lipoma of the right subclavian vein, growing into the right brachiocephalic vein.
CO<sub>2</sub> and Energy Exchange in a Rice Paddy for the Growing Season of 2002 in Hari, Korea
Byung-Kwan Moon,Jinkyu Hong,Byoung-Ryol Lee,Jin I. Yun,Eun Woo Park,Joon Kim Korean Society of Agricultural and Forest Meteorol 2003 한국농림기상학회지 Vol.5 No.2
한국 내 농경지의 약 60%를 차지하고 있는 논은 아시아의 주요 농업 생태계의 하나이다. 논은 대기로부터 $CO_2$를 흡수함과 동시에 CH$_4$의 형태로 탄소를 대기 중으로 방출하는데, 관개 상태에 따라 흡수와 방출의 상대적 크기가 달라져서 온실 기체의 전구 수지에 중요한 변수로 작용할 수 있다. 온실 효과와 관련하여 논의 현재 및 미래의 역할을 보다 잘 이해하기 위하여, 주요 농업 생태계에서의 $CO_2$와 에너지 교환을 정량화 하는 것은 매우 중요하다. 이 연구의 목적은, 벼의 전체 생장 기간동안 한국의 전형적인 논에서의 에너지와 $CO_2$ 교환과정을 관측, 분석하고 이해하는 것이다. 2002년 4월부터 한국 타워 플럭스 관측 지역망(KoFlux)에속한 강화도 하리의 논에서 $CO_2$ 및 에너지 플럭스 관측을 지속적으로 해오고 있다. 다양한 보정 단계와 처리 과정을 거친 관측 자료를 통해, 논과 대기간의 $CO_2$ 교환량을 정량화하고, 이를 미기상학적, 생물리학적 관점에서 분석하였다. 날씨 변화와 더불어, 지표 피복 변화와 식물의 생장 단계에 따라 $CO_2$ 교환량이 민감하게 변화하였다. 국내 논에서의 전 생장기간에 걸친 에너지와 $CO_2$ 교환에 관한 최초의 직접 관측 보고인 본 연구는, 아시아 플럭스망(AsiaFlux) 내에서 중요한 참고 자료로서의 가치를 지니며, 지면 모형의 보정과 개선, 전구 생지화학적 순환에 대한 논의 역할, 그리고 생물-대기 상호 작용에 대한 근본적인 이해를 향상시키는 데 기여할 것이다. Rice, which occupies about 60% of the farmland in Korea, is a staple crop in Asia. It not only absorbs $CO_2$ from the atmosphere, but also emits carbon in a form of CH$_4$. It has a potential role in the global budget of greenhouse gases because of its relative contributions of carbon absorption and emission associated with changing hydrologic cycle. To better understand its current and future role, seasonal variations of energy and $CO_2$ exchange in this critical ecosystem need to be quantified. The purpose of this study was to measure, document and understand the exchange of energy and $CO_2$ in a typical rice paddy in Korea throughout the whole growing season. Since late April of 2002, we have conducted measurements of energy and $CO_2$ exchange in a rural rice paddy at Hari site, one of the Korea regional network of tower flux measurement (KoFlux). After the quality control and gap-filling, the observed fluxes were analyzed in the context of micrometeorology and biophysics. $CO_2$ and energy exchanges varied significantly with land cover changes (e.g., plant growth stages), in addition to changes in weather and climate conditions. This study, reporting first direct measurement of energy and $CO_2$ exchange over a rice paddy in Korea, would serve as a useful database as one of the reference sites in AsiaFlux and FLUXNET.
증례 : 호흡기 ; 결핵 후 폐손상에 의한 만성 호흡 부전에서 발생한 장관 포상 기종 1예
양동진 ( Dong Jin Yang ),김현경 ( Hyun Kyung Kim ),류상열 ( Sang Ryol Ryu ),이병훈 ( Byoung Hoon Lee ),이재형 ( Jae Hyung Lee ),김상훈 ( Sang Hoon Kim ),조윤주 ( Yun Ju Jo ) 대한내과학회 2010 대한내과학회지 Vol.78 No.3
결핵 후 폐손상에 의한 만성 호흡 부전과 무증상의 기복증이 있던 69세 남자 환자가 1달 전부터 악화된 호흡곤란과 복부팽만을 주소로 내원하여, 장관 포상 기종과 기복증이 악화되어 복강천자와 산소요법 등의 비수술적인 치료로 호전된 증례를 경험하여 보고한다. Pneumatosis cystoides intestinalis is a rare condition characterized by gas-filled cysts within the bowel wall. It may be idiopathic or secondary to a variety of disorders. Associated conditions include chronic obstructive pulmonary disease, the use of non
결핵성 흉막염 치료 후 잔류된 만성 흉막삼출에서 발생한 가성유미흉
박은경 ( Eun Kyoung Park ),정숙희 ( Sook Hee Chung ),배준호 ( June Ho Bae ),류상열 ( Sang Ryol Ryu ),이재형 ( Jae Hyung Lee ),김상훈 ( Sang Hoon Kim ),조영욱 ( Young Uk Cho ),채정돈 ( Jeong Don Chae ),이병훈 ( Byoung Hoon Lee ) 대한결핵 및 호흡기학회 2009 Tuberculosis and Respiratory Diseases Vol.67 No.5
A pseudochylothorax, a chyliform pleural effusion, is a rare disease of pleural effusion that contains cholesterol crystals or high lipid content that is not the result of a disrupted thoracic duct. Most of the cases were found in patients with long-standing pleural effusion due to chronic inflammatory disease, such as old tuberculous pleurisy or chronic rheumatoid pleurisy. We experienced a case of pseudochylothorax in a 74-year-old man, who was being treated for pulmonary tuberculosis and pleurisy 10 years ago. The diagnosis was confirmed on pathological study of the pleural effusion, which contained cholesterol crystals having a diagnostic rhomboid appearance.
심하게 위축된 하악골의 완전 무치악 환자에서의 수직 골신장술을 이용한 임플란트 치료
염학렬,전승호,김윤태,팽준영,안강민,명훈,황순정,서병무,최진영,이종호,정필훈,김명진,Yeom, Hak-Ryol,Jeon, Seung-Ho,Kim, Yoon-Tae,Paeng, Jun-Young,Ahn, Kang-Min,Myung, Hoon,Hwang, Soon-Jung,Seo, Byoung-Moo,Choi, Jin-Young,Lee, Jong-Ho,Chou 대한악안면성형재건외과학회 2006 Maxillofacial Plastic Reconstructive Surgery Vol.28 No.2
Objectives : It is difficult to place implants at a severely atrophied edentulous mandible because of vertical and horizontal alveolar defect. The autogenous and allogenic bone graft and guided bone regeneration are useful, but there are some limitations such as the resorption and infection of the grafted bone, and insufficiency of soft tissue. Distraction osteogenesis has recently evolved a challenging technique to overcome major draws of conventional augmentation procedures, we, therefore, report the four applications of implant placement after vertical alveolar distraction osteogenesis. Patients and Methods : Four patients(all female, mean age: $60{\pm}6$ years) with severe alveolar ridge deficiencies at their anterior mandible were treated with vertical alveolar distraction osteogenesis by intraoral device(Track 1.5, 15 mm model, KLS Martin, Tuttlingen, Germany) and placement of implants (Branemark MK III, TiUnite). After the latency periods of 5, 7, 8 days, distraction rhythm and rate were $0.5\;mm{\times}2\;times/day$ in the case of good bone quality, and $0.25\;mm{\times}3\;times/day$ in the case of poor bone quality. After consolidation periods of mean fifteen weeks, five implants for each patients were placed at the interforaminal area. Results : On average, a vertical gain of $11.38{\pm}1.38\;mm$ was obtained by distraction. And all distraction zone showed complete ossification by panoramic radiography. There were no postoperative complications other than numbness of lower lip in one case. Total twenty implants in four patients were placed and their outcomes were satisfactory. Conclusion : It is a useful method to place five implants after vertical distraction osteogenesis of the severely atrophied mandible for the implant-supported fixed prosthesis.