胃癌細胞의 植物凝集素結合에 關한 免疫酵素組織學的 硏究

羅泳燦,廉範愚,金世民 고려대학교 의과대학 1984 고려대 의대 잡지 Vol.21 No.1

To evaluate the binding reactions of various phytohemagglutinins (PHAs) on the gastric carcinoma cells, the author had undertaken an experiment using purified PHAs, such as Concanavalin A(Con-A), wheat germ agglutinin(WGA), soybean agglutinin(SBA), Dolichos biflorus agglutinin(DBA), Ulex europaeus agglutinin I (UEA I), peanut agglutinin(PNA), Ricinus communis agglutinin I (RCA I), and Pinellia ternata agglutinin(PTA). The tissue samples used were gastric tissue from subtotal gastrectomy or fiberoptic biopsy, diagnosed by pathologists as well differentiated adenocarcinoma and poorly differentiated adenocarcinoma signet-ring cell type adenocarcinoma, and dysplasia. The results obtained are as follows; 1. On the well-differentiated adenocarcinoma, all the PHAs except UEA I showed cytoplasmic granular reactions of the tumor cells and linear reactions along the intraluminal borders of the tumor glands. 2. On the poorly differentiated adenocarcinoma, RCA I and UEA I showed cytoplasmic reactions, and other PHAs showed variable reactions from positive to focal positive. 3. In signet-ring cell carcinoma, PNA, SBA, RCA I and UEA I showed weak reactions in the cytoplasm. 4. On the dysplastic cells, Con-A, WGA, PNA, RCA I and PTA showed cytoplasmic reactions and SBA, UEA I and DBA showed no reaction. With the above results, the binding of PHAs on the tumor cells of the stomach reveled variable patterns, depending on the degree of differentiation and the kinds of PHAs used.

석회화 치성 낭종 1례

이상학,염범우,이승훈,한승훈,김응식,김광일 한국의학사 1998 診斷과治療 Vol.18 No.10

Synthesis of Flavanol-4-ol and its Spectroscopic Properties in Aqueous Solution

Yeom, Ji-Eun,Kumar, Manian Rajesh,Lee, Sun-Woo,Lee, Jee-Bum,Park, Hyoung-Ryun Korean Chemical Society 2011 Bulletin of the Korean Chemical Society Vol.32 No.11

Relationship between headache and mucosal mast cells in pediatric <i>Helicobacter pylori</i>-negative functional dyspepsia

Yeom, Jung Sook,Choi, Myung Bum,Seo, Ji-Hyun,Park, Ji Sook,Lim, Jae-Young,Park, Chan-Hoo,Woo, Hyang-Ok,Youn, Hee-Shang,Ko, Gyung-Hyuck,Baik, Seung-Chul,Lee, Woo-Kon,Cho, Myung-Je,Rhee, Kwang-Ho SAGE Publications 2013 Cephalalgia Vol.33 No.5

<P><B>Background</B></P><P>Although many patients with functional dyspepsia experience headache concurrently with dyspeptic symptoms, studies suggesting mechanisms underlying this phenomenon are limited. Herein, we explore the relationship between gastrointestinal inflammatory cells and presence of headache associated with dyspeptic symptoms in children with <I>Helicobacter pylori</I>-negative functional dyspepsia.</P><P><B>Methods</B></P><P>Fifty-six patients with <I>H. pylori</I>-negative functional dyspepsia underwent upper endoscopy with biopsy to investigate recurrent epigastric pain or discomfort. Patients were divided into two groups according to self-reported presence of headache associated with dyspeptic symptoms. Inflammatory cells including mast cells, and enteroendocrine cells in the gastroduodenal mucosa were evaluated. Associations between headache presence and cellular changes in the gastroduodenal mucosa were examined.</P><P><B>Results</B></P><P>Headache was not associated with the grade of lymphocytes, neutrophil infiltration, or enteroendocrine cell density in the gastroduedenal mucosa. However, headache was significantly associated with high mast cell density in the body (27.81 ± 8.71 vs. 20.30 ± 8.16, <I>p</I> < 0.01) and duodenum (23.16 ± 10.40 vs. 14.84 ± 5.88, <I>p</I> < 0.01).</P><P><B>Conclusions</B></P><P>Presence of headache associated with dyspeptic symptoms is strongly related to mucosal mast cell density in pediatric patients with <I>H. pylori</I>-negative functional dyspepsia. Thus, our results may help clinicians understand and treat headache during dyspeptic symptoms in such pediatric patients.</P>

A comparison of the Glidescope^Ⓡ to the McGrath^Ⓡ videolaryngoscope in patients

Woo Jae Jeon,Kyoung Hun Kim,Jong Hoon Yeom,Mi Rang Bang,Jin-Bum Hong,Sang Yun Cho 대한마취통증의학회 2011 Korean Journal of Anesthesiology Vol.61 No.1

Background: The Glidescope^Ⓡ videolaryngoscope is a new device for tracheal intubation that provides an improved view of the larynx. This study was performed to compare the Glidescope with the McGrath videolaryngoscope in terms of time to intubation (TTI) and number of attempts. Methods: Patients were randomly allocated to one of two groups, Glidescope or McGrath group, by using computergenerated numbers. Tracheal intubation was attempted by an anesthesiologist with extensive experience using these two devices. The operator recorded ease of visualization of glottic structures based on the classification described by Cormack and Lehane. Number of failures, number of attempts and their duration, total intubation time, and events during the whole procedure were recorded. The duration of one attempt was defined as the time elapsed between picking up the endotracheal tube and verification of tracheal intubation with visualization of three expiratory carbon dioxide waveforms. TTI was defined as the sum of the duration of all intubation attempts (as many as three),excluding preoxygenation procedures. Results: TTI was significantly shorter for the Glidescope^Ⓡ compared to the McGrath^Ⓡ laryngoscope (40.5 vs. 53.3 s,respectively, P < 0.05). However, glottic views obtained at intubation were similar between the two groups. Number of intubation attempts was not significantly different between the two groups (1.03 ± 0.19 vs 1.10 ± 0.32, respectively)(mean ± SD). Conclusions: Study results demonstrated that the Glidescope reduced total intubation time in comparison with the McGrath, in terms of TTI in patients with normal airways.

Parenting stress and interactive engagement behaviors in children with developmental delay

Yeom Jung Sook,Kim Rock Bum,Cho Jae Young,Park Ji Sook,Park Eun Sil,Seo Ji-Hyun,Lim Jae-Young,Woo Hyang-Ok 대한소아청소년과학회 2023 Clinical and Experimental Pediatrics (CEP) Vol.66 No.6

Background: In clinical practice, the importance of interactive engagement behaviors is overlooked in children with developmental problems other than autism spectrum disorder (ASD). Parenting stress affects children’s development but lacks attention from clinicians. Purpose: This study aimed to identify the characteristics of interactive engagement behaviors and parenting stress among non-ASD children with developmental delays (DDs). We also analyzed whether engagement behaviors affect parenting stress. Methods: At Gyeongsang National University Hospital, between May 2021 and October 2021, we retrospectively enrolled 51 consecutive patients diagnosed with DDs in language or cognition (but not ASD) in the delayed group and 24 typically developing children in the control group. The Korean version of the Parenting Stress Index-4 and Child Interactive Behavior Test were used to assess the participants. Results: The median age of the delayed group was 31.0 months (interquartile range, 25.0–35.5 months); this group included 42 boys (82.4%). There were no intergroup differences in child age, child sex, parental age, parental educational background, mother’s employment status, or marital status. Higher parenting stress (P<0.001) and fewer interactive engagement behaviors (P<0.001) were observed in the delayed group. Low parental acceptance and competence had the largest effects on total parenting stress in the delayed group. A mediation analysis revealed that DDs did not directly affect total parenting stress (β=3.49, P=0.440). Instead, DDs contributed to total parenting stress, which was mediated by children’s overall interactive engagement behaviors (β=57.30, P<0.001). Conclusion: Interactive engagement behaviors were significantly reduced in non-ASD children with DDs and significantly mediated parenting stress. The importance of parenting stress and interactive behaviors in children with DDs should be further examined in clinical practice.

산림치유 프로그램 내용구성을 위한 전문가 의견조사

염동걸(Yeom, Dong-geol),정다워(Joung, Dawou),김건우(Kim, Geon Woo),박범진(Park, Bum-Jin) 한국산림휴양복지학회 2015 한국산림휴양학회지 Vol.19 No.2

생애주기별 산림복지시설의 특성분석에 관한 연구

박범진 ( Bum Jin Park ),염동걸 ( Dong Geol Yeom ),김세빈 ( Se Bin Kim ),권치원 ( Chi Won Kyeon ),정다워 ( Da Wou Joung ),김건우 ( Geon Woo Kim ),최윤호 ( Yoon Ho Choi ) 한국산림과학회 2015 한국산림과학회지 Vol.104 No.2

This study aims to find some characteristics for the facilities of the ‘Korea Forest Welfare for Life Cycle’ through the domestic case analysis, so that we draw implications applicable to the policy on Korea Forest Welfare. For this, we brought and analyzed statistical data together from scattered sources. As the characteristics for the facilities of the Korea Forest Welfare for Life Cycle, first, there is the quantitative imbalance of forest welfare institutions for the each life cycle. Second, there is a lack of facilities in urban areas. Third, the facilities are mostly located in national or public forests. And, based on those characteristics, we suggest several things as follows that is applicable to the related policy. First, it is necessary to meet the needs of facilities that need to be built evenly for each life-cycle. Second, facilities of the Forest Welfare for Life Cycle which is adjacent to the life zone should be built more to increase accessibility. Third, forests in Korea are almost comprised of private forests. Using only national and public forests has an unfavorable condition to confer a benefits of forest welfare on the people evenly than using national, public and private forests all together. Therefore, there is a need to invigorate private capital and utilize private forests so that the favorable condition can be made to confer a benefits of forest welfare on the people evenly and adjust balance of the quantity for the facilities of forest welfare.

도심 수목원에서의 경관감상과 산책이 인체의 생리적 안정에 미치는 영향

박범진 ( Bum Jin Park ),가재남 ( Jae Nam Ka ),이민선 ( Min Sun Lee ),김선아 ( Seon A Kim ),박민우 ( Min Woo Park ),최윤호 ( Yoon Ho Choi ),정다워 ( Da Wou Joung ),권치원 ( Chi Weon Kwon ),염동걸 ( Dong Geol Yeom ),박순주 ( Soon Jo 한국산림과학회 2014 한국산림과학회지 Vol.103 No.4

This research was conducted to investigate the impact of viewing scenery and walking in the urban forest onphysiological relaxation of humans. The experiment was conducted in Hanbat Arboretum located in Daejeon, and thecontrol experiment was conducted in front of Daejeon City Hall. The subjects that participated in the experimentcomprised 24 Korean male university students in their 20s (average age, 21.1±2.5 years), participated in the experimentas the subject, and these subjects were classified into three groups divided into three locations such as the pine forest inArboretum, the pond in Arboretum, and the city. The subjects sat down and viewed scenery for 10 min, and they thenwalked for 15 min. Further, physiological changes were measured using indicators such as heart rate variability (HRV),blood pressure, and pulse rate. As a result, when subjects viewed scenery and walked in the urban forest, a statisticallysignificant increase in the high frequency (HF) power of HRV and decrease in systolic pressure was observed comparedwith when subjects viewed scenery and walked in the city. Through this research, it was found that activities like viewingscenery or walking in Arboretum of the city are effective in increasing the physiological relaxation of the city residents.

여름철 소나무림의 NVOC 배출특성 및 NVOC농도와 숲환경의 관계

김건우 ( Geon Woo Kim ),권치원 ( Chi Won Kwon ),염동걸 ( Dong Geol Yeom ),최윤호 ( Yoon Ho Choi ),정다워 ( Da Wou Joung ),박범진 ( Bum Jin Park ) 한국임학회 2014 산림과학 공동학술대회 논문집 Vol.2014 No.-

본 연구는 여름철 소나무림의 NVOC 배출특성과 배출된 농도와 숲의 물리환경과의 상관관계에 대하여 과학적으로 밝히기 위한 목적으로 수행되었다. 소나무림의 대기중 NVOC의 포집을 위해 2013년 6월부터 2013년 8월까지 총 5회의 실험을 진행하였으며 Tanax-Ta가 충진된 1회용 튜브와 미니펌프를 사용하여 포집하였다. 매회의 실험마다 일중시간동안 총 세 번의 시간(일출, 남중, 일몰)에 측정을 하였으며 오차를 줄이기 위하여 같은 지점에서 두 개의 튜브를 사용하여 측정후 분석한 평균값을 사용 하였다. 포집된 NVOC 물질 분석은 HS-SPME법을 사용하여 GC-MS로 분석하였다. 여름철 소나무림의 NVOC 배출특성을 확인한 결과, α-Pinene의 경우 6월에 10.15ng/m3으로 높게 검출되었으나 전체적인 농도(TNVOC)를 보았을 때 7월에 높은 농도를 보였으며 일몰시간에 높게 측정 되었다(α-Pinene : 4.05ng/m3, β-Pinene=2.48ng/m3). NVOC 농도와 숲의 물리환경과의 상관관계에 대하여 분석한 결과, α-Pinene, β-Pinene 등 대부분의 물질에서 습도(R2=0.284)가 높아질수록 농도가 높아졌으며 온도(R2=0.394), 이슬점(R2=0.223), 풍속(R2=0.169)이 클수록 농도가 낮아졌다. 연중 소나무림의 NVOC 농도는 7월 일출시간에 24.09ng/m3으로 가장 높은 것으로 확인되었다. 다만 다른 계절과 상이하게 여름철 소나무림의 상관관계에서 온도, 이슬점의 상승에 따라 농도가 낮아지는 경향을 보였다. 이는 NVOC 물질의 특성상 자연 상태에 존재 하였을 때 반감기가 존재한다고 알려져 있으며, 이러한 반감기는 온도와 광량에 따라 차이를 보이고 있는 것으로 추정된다. This study is carried out for the purpose of unveiling on the correlations between NVOC emission characteristic, emitted concentration, and forest physical environment in the summer scientifically. For the collection of NVOC in the atmosphere of pine forests, the experiment was conducted from June 2013 to August 2013 for a total of five times by using Tanax-Ta filled disposable tube and a mini-pump. Per each experiment, total 3 times (sunrise, culminating, sunset) during the day were measured and average value analysed after measuring by using two tubes at the same point to reduce measurement error. The collected NVOC substance analysis was analyzed with GC-MS by using HS-SPME method. The experiment result of NVOC emission characteristics of pine forest in summer present that α-Pinene was detected high at 10.15ng/m3 in June but overall concentration(TNVOC) is high in July and measured high in sunset time. (α-Pinene : 4.05ng/m3, β-Pinene=2.48ng/m3). The result of analysis on the correlation between NVOC concentration and physical environment of the forest shows when the humidity (R2=0.284) is high in most substances such as α-Pinene, β-Pinene, the concentrations becomes higher whereas temperature (R2 = 0.410), dew point (R2 = 0.555) and wind speed (R2 = 0.188) is greater, concentration become lower. The highest NVOC concentration of pine forests of the year is July and it reaches the highest 24.09ng/m3 during sunrise time. However, different from other seasons, the correlation between the pine forest in summer, increased in temperature and dew point tend to lower the concentration. A characteristic of the NVOC substance shown there is half-life when it is exist as natural state, such half-life is estimated to differ according to temperature and light quantity.