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      • Vascular hemodynamics and blood pressure differences between young and older women

        Brantley K. Ballenger,Gary R. Hunter,Gordon Fisher 대한고혈압학회 2022 Clinical Hypertension Vol.28 No.1

        Cardiovascular disease is one of the main causes of death in the United States, and hypertension is a primary risk factor. Therefore, the primary causes of hypertension need to be identified so they may be addressed for treatment. The purpose of this study was to compare blood pressure with hemodynamic values and identify factors that may explain blood pressure differences between a cohort of healthy normotensive younger and older women. Participants were 49 young (age: 33.8 ± 5.9) and 103 old (age: 65.8 ± 4) who were non-hypertensive, had no previous history of heart disease or type 2 diabetes, body mass index less than 30 kg/m 2 , normal electrocardiography response at rest and during exercise, nonsmokers, and no use of medications known to affect cardiovascular or metabolic function. Body composition measured by dual-energy X-ray absorptiometry. Hemodynamic values measured by non-invasive pulse wave velocity through radial artery tonometry. Markers of inflammation measured through blood sample analysis. Significant differences exist between young and old groups in %fat ( P < 0.001), systolic blood pressure (SBP) ( P = 0.001), large artery elasticity ( P = 0.005), small artery elasticity ( P < 0.001), systemic vascular resistance ( P = 0.004), total vascular impedance ( P < 0.001), estimated cardiac output ( P < 0.001), and tumor necrosis factor-⍺ (TNF-⍺) ( P < 0.001). Using ANCOVA the difference in SBP between age groups was no longer significant after adjusting for small artery elasticity ( P < 0.001) and TNF-⍺ ( P = 0.041). These data demonstrate that blood pressure and vascular hemodynamic measures differ significantly between young and old women independent of body composition. Furthermore, these differences may be explained by the inflammation marker TNF-⍺ and/or small artery elasticity.

      • Hydroxyapatite-silicon film deposited on Ti–Nb–10Zr by electrochemical and magnetron sputtering method

        Jeong, Yong-Hoon,Choe, Han-Cheol,Brantley, William A Elsevier 2016 THIN SOLID FILMS - Vol.620 No.-

        <P><B>Abstract</B></P> <P>The purpose of this study was to investigate silicon-doped hydroxyapatite (HA) films deposited on Ti–35Nb–10Zr by an electrochemical and magnetron sputtering method. The Ti–35Nb–10Zr alloy was manufactured in an arc-melting furnace. Electrochemical deposition of HA was performed by pulsing the potential, using cyclic voltammetry, in the electrolyte composed of 5mM·Ca(NO<SUB>3</SUB>)<SUB>2</SUB>·4H<SUB>2</SUB>O+6.0mM·NH<SUB>4</SUB>H<SUB>2</SUB>PO<SUB>4</SUB> at 85°C. The silicon doping was performed with a pure Si target by radio-frequency (RF) magnetron sputtering with variable deposition time. The surface characteristics were investigated by field-emission scanning electron microscopy, X-ray diffraction, and electrochemical corrosion testing. It was found that the Si particles on the electrochemically deposited HA layer became thicker with increased sputtering time. The composition of the Si-HA coating surface showed a decrease of the Ca/P ratio with increased sputtering time. The intensity of X-ray diffraction peaks for the HA coating was increased by annealing, and there were no phase changes or appearance of other peaks from the annealing treatment. From the corrosion test, an increase in Si sputtering time could cause higher corrosion potential and lower corrosion current density. Increasing the Si sputtering time increased the corrosion resistance in the passivation region.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Si sputtering was performed on the HA layer electrochemically deposited on the titanium alloy. </LI> <LI> The Si layer was deposited onto HA particles with a plate-like morphology. </LI> <LI> The Si particles in the layer became thicker with longer sputtering times. </LI> <LI> The crystallinity of the HA layer was not changed by Si sputtering. </LI> <LI> Corrosion resistance of the titanium alloy was increased with longer Si sputtering times. </LI> </UL> </P>

      • KCI등재

        Effect of Polymer Coating on the Corrosion Characteristics of Nickel-Titanium Orthodontic Archwire

        조주형,고영무,최한철,William A. Brantley 대한치과재료학회 2013 대한치과재료학회지 Vol.40 No.2

        본 연구는 NiTi 교정용 와이어의 부식특성에 미치는 폴리머코팅의 영향에 관하여 연구한 논문으로 교정용 와이어에 페릴린을 코팅하여 표면분석장비와 전기화학적인 부식시험을 통하여 다음과 같은 결과를 얻었다. 코팅된 표면은 작은 코팅 입자가 뭉쳐있는 모양을 보였으며 그 두께는 약 20 μm를 보였다. 표면 거칠기는 코팅되지 않은 경우는 0.381 μm를 코팅한 경우는 4.70 μm를 나타내었다. 공식전위는 코팅하지 않은 경우가 1240 mV를, 코팅한 경우는 공식전위가 나타나지 않았다. 300 mV에서 전류밀도는 코팅하지 않은 경우가 2.99×10-6 A/cm2를, 코팅한 경우가 2.13×10-7 A/cm2를 각각 나타내었다. 정전위나 정전류 실험으로부터 내식성은 코팅한 경우가 증가하는 경향으로 나타났다.

      • SCIESCOPUSKCI등재

        A study of fracture loads and fracture characteristics of teeth

        Sheen, Chang-Yong,Dong, Jin-Keun,Brantley, William Arthur,Han, David Seungho The Korean Academy of Prosthodonitics 2019 The Journal of Advanced Prosthodontics Vol.11 No.3

        PURPOSE. The purpose of this in vitro study was to investigate the fracture loads and modes of failure for the full range of natural teeth under simulated occlusal loading. MATERIALS AND METHODS. One hundred and forty natural teeth were taken from mandibles and maxillas of patients. There were 14 groups of teeth with 10 teeth in each group (5 males and 5 females). Each specimen was embedded in resin and mounted on a positioning jig, with the long axis of the tooth at an inclined angle of 30 degrees. A universal testing machine was used to measure the compression load at which fracture of the tooth specimen occurred; loads were applied on the incisal edge and/or functional cusp. RESULTS. The mean fracture load for the mandibular first premolar was the highest (2002 N) of all the types of teeth, while the mean fracture load for the maxillary first premolar was the lowest (525 N). Mean fracture loads for the mandibular and maxillary incisors, and the first and second maxillary premolars, had significantly lower values compared to the other types of teeth. The mean fracture load for the teeth from males was significantly greater than that for the teeth from females. There was an inverse relationship between age and mean fracture load, in which older teeth had lower fracture loads compared to younger teeth. CONCLUSION. The mean fracture loads for natural teeth were significantly different, with dependence on tooth position and the sex and age of the individual.

      • Nanotube nucleation phenomena on Ti-25Ta-xZr alloys for implants using ATO technique.

        Kim, Hyun-Ju,Jeong, Yong-Hoon,Brantley, William A,Choe, Han-Cheol American Scientific Publishers 2014 Journal of Nanoscience and Nanotechnology Vol.14 No.10

        <P>The purpose of this study was to investigate nanotube nucleation phenomena on the Ti-25Ta-xZr alloys for implant materials, using an anodic titanium oxide (ATO) technique. Ti-25Ta-(0 wt.%-15 wt.%) Zr alloys were prepared using a vacuum arc-melting furnace. The Ti-25Ta-xZr alloys were then homogenized for 12 hr at 1000 degrees C, followed by water quenching. Formation of the nanotubular oxide surface structure was achieved initially on the Ti-25Ta-xZr alloys by anodization in a 1 M H3PO4 electrolyte containing 0.8 wt.% NaF at room temperature, using a potentiostat. After the first formation of the nanotubes was achieved, this initial nanotube layer was eliminated, and further anodization was carried out repeatedly. The microstructure, phase transformation, and morphology of nanotubular Ti-25Ta-xZr alloys and the process of nanotube growth using this ATO method were analyzed by X-ray diffraction, field-emission scanning electron microscopy, and energy dispersive X-ray spectroscopy. Microstructures of the Ti-25Ta-xZr alloys changed from α' phase to β phase. Nanotubes formed with the ATO technique had pit-like top holes, with thinner walls and lower contact angle, compared to the initially formed nanotubes.</P>

      • Hydroxyapatite precipitation on nanotube surfaces of Ti-35Ta-xNb alloys.

        Jo, Chae-Ik,Jeong, Yong-Hoon,Brantley, William A,Choe, Han-Cheol American Scientific Publishers 2014 Journal of Nanoscience and Nanotechnology Vol.14 No.10

        <P>Hydroxyapatite precipitation on nanotube surfaces of Ti-35Ta-xNb alloys was investigated using electrochemical methods. The alloys were prepared by arc-melting, heat treated at 1050 degrees C for 12 h in an Ar atmosphere, and quenched in 0 degrees C water. Nanotubes were created on the Ti-35Ta-xNb alloys in a 1 M H3PO4 + 1.2 wt.% NaF electrolyte at room temperature. Hydroxyapatite precipitation was carried out in a 0.03 M Ca(NO3)2 x 4H2O + 0.018 M NH4H2PO4 solution at 80 1 degrees C, using 10 deposition cycles. Information about morphology and composition was obtained by FE-SEM and EDS. The microstructure of the Ti-35Ta-xNb alloys was transformed from α phase to βphase as the Nb content increased. The HA precipitates had a plate-like morphology on bulk Ti-35Ta-xNb alloys and a flower-like morphology on nanotubular Ti-35Ta-xNb alloys.</P>

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