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( Bo Ram Kang ),( Ho Kim ),( Sung Hee Nam ),( Eun Young Yun ),( Seong Ryul Kim ),( Mi Young Ahn ),( Jong Soo Chang ),( Jae Sam Hwang ) 생화학분자생물학회 (구 한국생화학분자생물학회) 2012 BMB Reports Vol.45 No.2
Our previous study demonstrated that CopA3, a disulfide dimer of the coprisin peptide analogue (LLCIALRKK), has antibacterial activity. In this study, we assessed whether CopA3 caused cellular toxicity in various mammalian cell lines. CopA3 selectively caused a marked decrease in cell viability in Jurkat T, U937, and AML-2 cells (human leukemia cells), but was not cytotoxic to Caki or Hela cells. Fragmentation of DNA, a marker of apoptosis, was also confirmed in the leukemia cell lines, but not in the other cells. CopA3-induced apoptosis in leukemia cells was mediated by apoptosis inducing factor (AIF), indicating induction of a caspase-independent signaling pathway. [BMB reports 2012; 45(2): 85-90].
Beneficial effect of agar mask against skin damages induced by UV exposure in SKH-1 hairless mice
Bo Ram Song,Ji Eun Kim,Woo Bin Yun,Mi Rim Lee,Jun Young Choi,Jin Ju Park,Dong Seob Kim,Chung Yeoul Lee,Hee Seob Lee,Yong Lim,Min Wook Jung,Bae Hwan Kim,Dae Youn Hwang 한국실험동물학회 2017 한국실험동물학회 학술발표대회 논문집 Vol.2017 No.8
Bo Ram Kim,백희조,Yoon Jung Choi,Yun Young Lee,Joheon Kim,국훈 대한소아혈액종양학회 2022 Clinical Pediatric Hematology-Oncology Vol.29 No.1
Extramedullary relapse in acute lymphoblastic leukemia (ALL) usually occurs in the central nervous system and testes those are known as sanctuary sites. Only a few cases of isolated breast relapse after allogeneic hematopoietic stem cell transplantation (HSCT) have been reported in pediatric ALL, with little known about the optimal treatment and prognosis of such cases. Herein, we report a pediatric case of isolated breast relapse with early T-cell precursor ALL after HSCT. We also describe a liter-ature review of six pediatric cases, including our case.