A Context Aware Gateway for SIP-based Services in Ubiquitous Smart Homes

Bo-Chao Cheng,Huan Chen,Ryh-Yuh Tseng 보안공학연구지원센터 2008 International Journal of Smart Home Vol.2 No.1

The smart home concept brings innovation and convenience to our every day's life style. Without context awareness, smart home applications can neither offer adaptive services based on users’ dynamic situations nor provide preferential treatments according to users’ various preferences. Such a design paradigm forces human to live in the world of machines rather than a human-centric world. The use of SIP-protocol allows smart home devices and services to be connected compatibly and effectively. In this paper, we propose an adaptive SIP Context Aware Gateway (SIP-CAG) for the ubiquitous SIP-based services. With the SIPCAG solution, the home owner is able to use preferred devices for communication and to post his/her context information to home appliances or to people and civil society communities on an “as needed” basis.

Apoptosis-inducing effect and structural basis of Polygonatum cyrtonema Lectin and chemical modification properties on its mannose-binding sites

( Bo Liu ),( Xiao Chao Xu ),( Yan Cheng ),( Jian Huang ),( Yan Hong Liu ),( Zhen Liu ),( Ming Wei Min ),( He Jiao Bian ),( Jing Chen ),( Jin Ku Bao ) 생화학분자생물학회 2008 BMB Reports Vol.41 No.5

A Superhydrophilic and Anti-Biofouling Polyphenylene Sulfide Microporous Membrane with Quaternary Ammonium Salts

Chao Wang,Zhenhuan Li,Lei Cao,Bo-wen Cheng 한국고분자학회 2018 Macromolecular Research Vol.26 No.9

Polyphenylene sulfide (PPS) membranes were modified by chloromethylation and quaternary amination reaction to prepare a hydrophilic PPS microporous membrane. The structures of the modified PPS membranes were characterized by the use of Fourier transform infrared spectroscopy, X-ray photoelectron spectroscopy, and scanning electron microscopy. The results showed that the modified membranes maintain the same microporous structures as the PPS membrane. The hydrophilicity of the modified membranes was significantly improved compared to that of the PPS membranes, and the water flux of N-methylimidazole modified membranes, triethylamine modified membranes, and both mixture modified membranes achieved 110.475, 168.94, 150.59 L·m-2·h-1, respectively. The quaternary amination of the PPS membranes made much less bovine serum albumin (BSA) pollution accumulation on the top surface of the modified membranes, and there was a significant improvement, to 94%, in the BSA rejection rate. Most importantly, the antibacterial activity of the modified membranes was effectively improved, and the bactericidal rate was elevated to above 80% in comparison with pure PPS membranes, which was attributed to the introduction of quaternary ammonium salts and imidazolium salts in out-surface of the membranes.

Protective effect of acacetin on sepsis-induced acute lung injury via its anti-inflammatory and antioxidative activity

Li-chao Sun,Hong-bo Zhang,Cheng-Dong Gu,Shi-Dong Guo,Gang Li,Rui Lian,Yao Yao,Guo-qiang Zhang 대한약학회 2018 Archives of Pharmacal Research Vol.41 No.12

Sepsis is a clinical syndrome with no effective protective or therapeutic treatments. Acacetin, a natural flavonoid compound, has anti-oxidative and anti-inflammatory effects which can potentially work to reduce sepsis. We investigated the potential protective effect of acacetin on sepsis-induced acute lung injury (ALI) ALI and dissect out the underlying mechanisms. Mice were divided into five groups: a sham group, a sepsis-induced ALI group, and three sepsis groups pre-treated with 20, 40, and 80 mg/kg body weight of acacetin. We found that acacetin significantly attenuated sepsis-induced ALI, in histological examinations and lung edema. Additionally, acacetin treatment decreased protein and inflammatory cytokine concentration and the number of infiltrated inflammatory cells in BALF compared with that in the non-treated sepsis mice. Pulmonary myeloperoxidase (MPO) activity was lower in the acacetin-pre-treated sepsis groups than in the sepsis group. The mechanism underlying the protective effect of acacetin on sepsis is related to the regulation of certain antioxidation genes, including inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), superoxide dismutases (SODs), and heme oxygenase 1 (HO-1).Taken together, our results indicate that acacetin pre-treatment inhibits sepsis-induced ALI through its anti-inflammatory and antioxidative activity, suggesting that acacetin may be a potential protective agent for sepsis-induced ALI.

Plasma metabolites associated with physiological and biochemical indexes indicate the effect of caging stress on mallard ducks (Anas platyrhynchos)

Zheng Chao,Wu Yan,Liang Zhen Hua,Pi Jin Song,Cheng Shi Bin,Wei Wen Zhuo,Liu Jing Bo,Lu Li Zhi,Zhang Hao 아세아·태평양축산학회 2022 Animal Bioscience Vol.35 No.2

Objective: Cage rearing has critical implications for the laying duck industry because it is convenient for feeding and management. However, caging stress is a type of chronic stress that induces maladaptation. Environmental stress responses have been extensively studied, but no detailed information is available about the comprehensive changes in plasma metabolites at different stages of caging stress in ducks. We designed this experiment to analyze the effects of caging stress on performance parameters and oxidative stress indexes in ducks. Methods: Liquid chromatography tandem mass spectrometry (LC/MS-MS) was used to determine the changes in metabolites in duck plasma at 5 (CR5), 10 (CR10), and 15 (CR15) days after cage rearing and traditional breeding (TB). The associated pathways of differentially altered metabolites were analyzed using Kyoto encyclopedia of genes and genomes (KEGG) database. Results: The results of this study indicate that caging stress decreased performance parameters, and the plasma total superoxide dismutase levels were increased in the CR10 group compared with the other groups. In addition, 1,431 metabolites were detected. Compared with the TB group, 134, 381, and 190 differentially produced metabolites were identified in the CR5, CR10, and CR15 groups, respectively. The results of principal component analysis (PCA) show that the selected components sufficiently distinguish the TB group and CR10 group. KEGG analysis results revealed that the differentially altered metabolites in duck plasma from the CR5 and TB groups were mainly associated with ovarian steroidogenesis, biosynthesis of unsaturated fatty acids, and phenylalanine metabolism. Conclusion: In this study, the production performance, blood indexes, number of metabolites and PCA were compared to determine effect of the caging stress stage on ducks. We inferred from the experimental results that caging-stressed ducks were in the sensitive phase in the first 5 days after caging, caging for approximately 10 days was an important transition phase, and then the duck continually adapted. Objective: Cage rearing has critical implications for the laying duck industry because it is convenient for feeding and management. However, caging stress is a type of chronic stress that induces maladaptation. Environmental stress responses have been extensively studied, but no detailed information is available about the comprehensive changes in plasma metabolites at different stages of caging stress in ducks. We designed this experiment to analyze the effects of caging stress on performance parameters and oxidative stress indexes in ducks.Methods: Liquid chromatography tandem mass spectrometry (LC/MS-MS) was used to determine the changes in metabolites in duck plasma at 5 (CR5), 10 (CR10), and 15 (CR15) days after cage rearing and traditional breeding (TB). The associated pathways of differentially altered metabolites were analyzed using Kyoto encyclopedia of genes and genomes (KEGG) database.Results: The results of this study indicate that caging stress decreased performance parameters, and the plasma total superoxide dismutase levels were increased in the CR10 group compared with the other groups. In addition, 1,431 metabolites were detected. Compared with the TB group, 134, 381, and 190 differentially produced metabolites were identified in the CR5, CR10, and CR15 groups, respectively. The results of principal component analysis (PCA) show that the selected components sufficiently distinguish the TB group and CR10 group. KEGG analysis results revealed that the differentially altered metabolites in duck plasma from the CR5 and TB groups were mainly associated with ovarian steroidogenesis, biosynthesis of unsaturated fatty acids, and phenylalanine metabolism.Conclusion: In this study, the production performance, blood indexes, number of metabolites and PCA were compared to determine effect of the caging stress stage on ducks. We inferred from the experimental results that caging-stressed ducks were in the sensitive phase in the first 5 days after caging, caging for approximately 10 days was an important transition phase, and then the duck continually adapted.

Paleogene lacustrine dolomitization, Xingou region, southern Qianjiang Depression, China

Junjun Shen,Bo Chen,Fangfang Chen,Chao Cheng,Yangfan Li,Ying Tian 한국지질과학협의회 2016 Geosciences Journal Vol.20 No.2

The lacustrine dolomicrites of Unit II of the lower Xingouzui Formation deposited in the southern part of the Qianjiang Depression provide a good “tight carbonate” hydrocarbon reservoir. The dolomicrites are typically interbedded with and sourced from organic-rich argillite, which together form a source-reservoir assemblage characterized by thin single-layer thicknesses, far lateral extent and continuous lateral distribution. Systematic sedimentological and geochemical studies indicate that the depositional environment and organic matter evolution of the dark argillites (with TOC of 0.5–2%) are favorable for formation of the dolomicrites. The dolomicrite was mainly formed in a shallow-water evaporative environment; crystals are anhedral under SEM, in non-surface contact, and include a number of honeycomb intergranular micropores associated with replacement. The dolomicrite shows orange-orangered light by cathodoluminescence, indicative of association with minor terrigenous debris; X-ray diffraction results indicate that the dolomicrite is characterized by high calcium content (CaCO3 molar contents of 52.28–52.28%), low degree of orders of 0.2–0.4), and high content of Fe. The dolomicrite has δ18O values of 2.47–2.47‰ PDB, more positive than micrite, and δ13C values as moderately negative as 9.4–4.21‰ PDB, similar to micrite. Both values indicate the dolomicrite formed in a low-temperature genetic zone. Together, these characteristics indicate that the dolomicrite in the study area was formed in a high-salinity, confined lake basin, characterized by low temperature, shallow burial, and rapid nucleation and crystallization. The dolomicrite experienced a contemporaneous period with formation of dark mudstone, shale and calcite, and a penecontemporaneous period with formation of dolomicrite via seepage-reflux and a diagenetic period when ferrodolomite was formed via burial.

Preparation and BSA Adsorption Behavior of Chitosan-arginine Based Nanofiber Membranes

Xiaojie Li,Guiqun Chao,Liangan Wang,Xianlin Xu,Zhanjun Cai,Lei Shi,Xupin Zhuang,Bo-wen Cheng 한국섬유공학회 2018 Fibers and polymers Vol.19 No.5

In this work, an affinity nanofiber membrane was successfully prepared by solution blowing of arginine-modified chitosan (CS-Arg) for bovine serum albumin (BSA) adsorption. CS-Arg was firstly synthesized by coupling L-arginine onto chitosan backbone. Then, CS-Arg nanofiber membranes (CANFs) were fabricated using solution blowing process with Polylactide (PLA) as assistant polymer. The results showed that CANFs effectively adsorbed BSA, and the adsorption capacities were influenced by the degrees of substitution (DS) of arginine in CS, pH value, contact time, and initial protein concentration. The highest adsorption capacity of 445.19 mg/g was achieved uvnder the following conditions: DS of 43.7 %, pH of 7.14, and initial concentration of 3.0 mg/ml. BSA adsorbed on the CANFs membrane conformed to Langmuir model, and the adsorption rate was consistent with the second-order kinetics model. This work implies that an arginine-modified chitosan nanofiber-based novel biomaterial has a potential application in adsorption of BSA.

Minimal Information Loss for Privacy-Preserved eHealth Applications

Ya-Ling Chen,Bo-Chao Cheng,Hsueh-lin Chen,Chia-I Lin,Guo-Tan Liao,Bo-Yu Hou,Shih-Chun Hsu 보안공학연구지원센터 2012 International Journal of Security and Its Applicat Vol.6 No.2

Two-Layer Security Scheme for AMI System

Ping-Hai Hsu,Wenshiang Tang,Chiakai Tsai,Bo-Chao Cheng 한국정보기술융합학회 2011 JoC Vol.2 No.1

Selective Radiotherapy after Distant Metastasis of Nasopharyngeal Carcinoma Treated with Dose-Dense Cisplatin plus Fluorouracil

Liang, Yong,Bu, Jun-Guo,Cheng, Jin-ling,Gao, Wei-Wei,Xu, Yao-Can,Feng, Jian,Chen, Bo-Yu,Liang, Wei-Chao,Chen, Ke-Quan Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.14

Purpose: To investigate the efficacy and safety of selective radiotherapy after distant metastasis of nasopharyngeal carcinoma (NPC) treated with dose-dense cisplatin plus fluorouracil. Materials and Methods: Eligible patients were randomly assigned to a study group treated with dose-dense cisplatin plus fluorouracil following selective radiotherapy and a control group receiving traditional cisplatin plus fluorouracil following selective radiotherapy according to a 1:1 distribution using a digital random table method. The primary endpoint was overall survival (OS). Secondary endpoints were progression-free survival (PFS), objective response rate, relapse or progression rate in the radiation field and treatment toxicity. Results: Of 52 patients in the study group, 20 cases underwent radiotherapy., while in the control group of 51 patients, 16 underwent radiotherapy. The median PFS, median OS, survival rates in 1, 2 and 3 years in study and control group were 20.9 vs 12.7months, 28.3 vs 18.8months, 85.2%vs 65.9%, 62.2% vs 18.3%, and 36.6%vs 5.2% (p values of 0.00, 0.00, 0.04, 0.00 and 0.00, respectively). Subgroup analysis showed that the median OS and survival rates of 1, 2, 3 years for patients undergoing radiotherapy in the study group better than that in control group( 43.2vs24.1 months, 94.1% vs 86.7%, 82.4% vs 43.3%, 64.7% vs 17.3%, (p=0.00, 0.57, 0.04 and 0.01, respectively). The complete response rate, objective response rate after chemotherapy and three months after radiotherapy, relapse or progression rate in radiation field in study group and in control group were 19.2% vs 3.9%, 86.5% vs 56.9%, 85% vs 50%, 95% vs 81.3% and 41.3% vs 66.7% (p =0.03, 0.00, 0.03,0.30, 0.01 respectively). The grade 3-4 acute adverse reactions in the study group were significantly higher than in the control group (53.8% vs 9.8%, p=0.00). Conclusions: The survival of patients benefits from selective radiotherapy after distant metastasis of NPC treated with dose-dense cisplatin plus fluorouracil.