An advanced Parallel FPGA Architecture for Bi-directional Motion Estimation

Yangfan Huang,Minjun Deng,Donglian Li,Zhenzhen Li,Mingyan Yu,Cailan Zeng,Yu Zhang,Zhuo Chen,Pengcheng Cao,Ran Liu 보안공학연구지원센터 2015 International Journal of Hybrid Information Techno Vol.8 No.9

Motion estimation (ME) and motion compensation (MC) are the key elements for frame rate up-conversion (FRUC) system. Fast and accurate motion estimation is the premise of high quality motion compensation. Unlike conventional unidirectional motion estimation which brings holes, overlaps and blocking artifacts, the bi-directional motion estimation does not produce any overlapped pixel or hole in the interpolated frames. As a result, the bi-directional motion estimation has better performance than conventional unidirectional motion estimation. This paper presents an efficient FPGA architecture targeting bi-directional motion estimation hardware implementation. This proposed architecture can achieve real-time processing for 1280x720@60Hz under 200MHz operating frequency. The design is described in Verilog HDL, verified in Virtex5 FPGA platform. Experimental results show that the proposed architecture has high performance and low cost for bi-directional motion estimation algorithm. This architecture can be used for video post-processing system.

Catalytic Degradation of Poly(Vinyl Alcohol) by FexMnyCuzOw/γ-Al2O3 Nano-particles Catalyst Using Box-Behnken Design

Yangfan Su,Mengjuan Li,Mingqiao Ge 한국섬유공학회 2019 Fibers and polymers Vol.20 No.9

FexMnyCuzOw/γ-Al2O3 nanoparticles were prepared by a wet impregnation -calcination method and characterizedby means of XRD, BET, SEM-EDS. Box-Behnken design was used to investigate the degradation of PVA in aqueoussolution. Besides, the effect of different calcination temperature, FexMnyCuzOw/γ-Al2O3 dosage, H2O2 dosage, initial PVAconcentration and initial solution pH on the removal of PVA were also studied. Results showed that PVA can be efficientlyremoved and oxidized by the heterogeneous Fenton-like process with appropriate amount of FexMnyCuzOw/γ-Al2O3 andH2O2. In this paper, the efficiency of PVA was above 90 % by FexMnyCuzOw/γ-Al2O3 nanoparticles at an initial PVAconcentration below 25 g/l, temperature at 60 oC, initial pH from 1.0 to 6.0, H2O2 and catalyst dose of 60 ml/l and 0.5 g/l,respectively. In addition, chromatography (GPC) was applied to further analyze the degradation of PVA under differentexperimental conditions, which revealed that the backbone chain of PVA could be effectively broken and oxidized. Severalunsaturated degradation products, including butanones, benzaldehydes, hexanals and acetic acids were also detected andidentified by gas chromatography-mass spectrometry (GC-MS). Besides, the nano catalyst maintained favorable catalyticability during the five-times utilization, which means it could be recycled by filtration and calcination.

Ginsenoside Rb1 exerts neuroprotective effects through regulation of Lactobacillus helveticus abundance and GABA_A receptor expression

Chen, Huimin,Shen, Jiajia,Li, Haofeng,Zheng, Xiao,Kang, Dian,Xu, Yangfan,Chen, Chong,Guo, Huimin,Xie, Lin,Wang, Guangji,Liang, Yan The Korean Society of Ginseng 2020 Journal of Ginseng Research Vol.44 No.1

Background: Ginsenoside Rb1 (Rb1), one of the most abundant protopanaxadiol-type ginsenosides, exerts excellent neuroprotective effects even though it has low intracephalic exposure. Purpose: The present study aimed to elucidate the apparent contradiction between the pharmacokinetics and pharmacodynamics of Rb1 by studying the mechanisms underlying neuroprotective effects of Rb1 based on regulation of microflora. Methods: A pseudo germ-free (PGF) rat model was established, and neuroprotective effects of Rb1 were compared between conventional and PGF rats. The relative abundances of common probiotics were quantified to reveal the authentic probiotics that dominate in the neuroprotection of Rb1. The expressions of the gamma-aminobutyric acid (GABA) receptors, including GABAA receptors (α2, β2, and γ2) and GABAB receptors (1b and 2), in the normal, ischemia/reperfusion (I/R), and I/R+Rb1 rat hippocampus and striatum were assessed to reveal the neuroprotective mechanism of Rb1. Results: The results showed that microbiota plays a key role in neuroprotection of Rb1. The relative abundance of Lactobacillus helveticus (Lac.H) increased 15.26 fold after pretreatment with Rb1. I/R surgery induced effects on infarct size, neurological deficit score, and proinflammatory cytokines (IL-1β, IL-6, and TNF-α) were prevented by colonizing the rat gastrointestinal tract with Lac.H (1 × 10⁹ CFU) by gavage 15 d before I/R surgery. Both Rb1 and Lac.H upregulated expression of GABA receptors in I/R rats. Coadministration of a GABA_A receptor antagonist significantly attenuated neuroprotective effects of Rb1 and Lac.H. Conclusion: In sum, Rb1 exerts neuroprotective effects by regulating Lac.H and GABA receptors rather than through direct distribution to the target sites.

Ginsenoside Rb1 exerts neuroprotective effects through regulation of Lactobacillus helveticus abundance and GABA<SUB>A</SUB> receptor expression

Huimin Chen,Jiajia Shen,Haofeng Li,Xiao Zheng,Dian Kang,Yangfan Xu,Chong Chen,Huimin Guo,Lin Xie,Guangji Wang,Yan Liang 고려인삼학회 2020 Journal of Ginseng Research Vol.44 No.1

Background: Ginsenoside Rb1 (Rb1), one of the most abundant protopanaxadiol-type ginsenosides, exerts excellent neuroprotective effects even though it has low intracephalic exposure. Purpose: The present study aimed to elucidate the apparent contradiction between the pharmacokinetics and pharmacodynamics of Rb1 by studying the mechanisms underlying neuroprotective effects of Rb1 based on regulation of microflora. Methods: A pseudo germ-free (PGF) rat model was established, and neuroprotective effects of Rb1 were compared between conventional and PGF rats. The relative abundances of common probiotics were quantified to reveal the authentic probiotics that dominate in the neuroprotection of Rb1. The expressions of the gamma-aminobutyric acid (GABA) receptors, including GABAA receptors (α2, β2, and γ2) and GABAB receptors (1b and 2), in the normal, ischemia/reperfusion (I/R), and I/RþRb1 rat hippocampus and striatum were assessed to reveal the neuroprotective mechanism of Rb1. Results: The results showed that microbiota plays a key role in neuroprotection of Rb1. The relative abundance of Lactobacillus helveticus (Lac.H) increased 15.26 fold after pretreatment with Rb1. I/R surgery induced effects on infarct size, neurological deficit score, and proinflammatory cytokines (IL-1β, IL-6, and TNF-α) were prevented by colonizing the rat gastrointestinal tract with Lac.H (1×10<SUP>9</SUP> CFU) by gavage 15 d before I/R surgery. Both Rb1 and Lac.H upregulated expression of GABA receptors in I/R rats. Coadministration of a GABAA receptor antagonist significantly attenuated neuroprotective effects of Rb1 and Lac.H. Conclusion: In sum, Rb1 exerts neuroprotective effects by regulating Lac.H and GABA receptors rather than through direct distribution to the target sites.

Finite-time Synchronization of a Class of Coupled Memristor-based Recurrent Neural Networks: Static State Control and Dynamic Control Approach

Chao Yang,Yicheng Liu,Fangmin Li,Yangfan Li 제어·로봇·시스템학회 2021 International Journal of Control, Automation, and Vol.19 No.1

This paper investigates the problem of the finite-time synchronization of a class of coupled memristorbased recurrent neural networks (MRNNs) with time delays. Based on the drive-response concept and differentialinclusions theory, several sufficient assumptions are given to ensure the finite-time synchronization of MRNNs. In order to realize the finite-time synchronization between the drive system and the response system, we designthree classes of novel control rules such as static state controller, static output controller, dynamic state controller. Using the theory of differential inclusion, a generalized finite-time convergence theorem and Lyapunov method, theconditions herein are easy to be verified. Moreover, the upper bounds of the settling time of synchronization areestimated and the designed dynamic state controllers have good anti-interference capacity. Finally, two numericalexamples are presented to illustrate the effectiveness and the validity of theoretical results.

Ginsenoside Rb1 exerts neuroprotective effects through regulation of Lactobacillus helveticus abundance and GABAA receptor expression

Huimin Chen,Jiajia Shen,Haofeng Li,Xiao Zheng,Dian Kang,Yangfan Xu,Chong Chen,Huimin Guo,Lin Xie,Guangji Wang,Yan Liang 고려인삼학회 2020 Journal of Ginseng Research Vol.44 No.1

Background: Ginsenoside Rb1 (Rb1), one of the most abundant protopanaxadiol-type ginsenosides, exertsexcellent neuroprotective effects even though it has low intracephalic exposure. Purpose: The present study aimed to elucidate the apparent contradiction between the pharmacokineticsand pharmacodynamics of Rb1 by studying the mechanisms underlying neuroprotective effects ofRb1 based on regulation of microflora. Methods: A pseudo germ-free (PGF) rat model was established, and neuroprotective effects of Rb1 werecompared between conventional and PGF rats. The relative abundances of common probiotics werequantified to reveal the authentic probiotics that dominate in the neuroprotection of Rb1. The expressionsof the gamma-aminobutyric acid (GABA) receptors, including GABAA receptors (a2, b2, and g2) andGABAB receptors (1b and 2), in the normal, ischemia/reperfusion (I/R), and I/RþRb1 rat hippocampus andstriatum were assessed to reveal the neuroprotective mechanism of Rb1. Results: The results showed that microbiota plays a key role in neuroprotection of Rb1. The relativeabundance of Lactobacillus helveticus (Lac.H) increased 15.26 fold after pretreatment with Rb1. I/R surgeryinduced effects on infarct size, neurological deficit score, and proinflammatory cytokines (IL-1b, IL-6, andTNF-a) were prevented by colonizing the rat gastrointestinal tract with Lac.H (1 109 CFU) by gavage 15d before I/R surgery. Both Rb1 and Lac.H upregulated expression of GABA receptors in I/R rats. Coadministrationof a GABAA receptor antagonist significantly attenuated neuroprotective effects of Rb1 and Lac.H. Conclusion: In sum, Rb1 exerts neuroprotective effects by regulating Lac.H and GABA receptors ratherthan through direct distribution to the target sites.

Paleogene lacustrine dolomitization, Xingou region, southern Qianjiang Depression, China

Junjun Shen,Bo Chen,Fangfang Chen,Chao Cheng,Yangfan Li,Ying Tian 한국지질과학협의회 2016 Geosciences Journal Vol.20 No.2

The lacustrine dolomicrites of Unit II of the lower Xingouzui Formation deposited in the southern part of the Qianjiang Depression provide a good “tight carbonate” hydrocarbon reservoir. The dolomicrites are typically interbedded with and sourced from organic-rich argillite, which together form a source-reservoir assemblage characterized by thin single-layer thicknesses, far lateral extent and continuous lateral distribution. Systematic sedimentological and geochemical studies indicate that the depositional environment and organic matter evolution of the dark argillites (with TOC of 0.5–2%) are favorable for formation of the dolomicrites. The dolomicrite was mainly formed in a shallow-water evaporative environment; crystals are anhedral under SEM, in non-surface contact, and include a number of honeycomb intergranular micropores associated with replacement. The dolomicrite shows orange-orangered light by cathodoluminescence, indicative of association with minor terrigenous debris; X-ray diffraction results indicate that the dolomicrite is characterized by high calcium content (CaCO3 molar contents of 52.28–52.28%), low degree of orders of 0.2–0.4), and high content of Fe. The dolomicrite has δ18O values of 2.47–2.47‰ PDB, more positive than micrite, and δ13C values as moderately negative as 9.4–4.21‰ PDB, similar to micrite. Both values indicate the dolomicrite formed in a low-temperature genetic zone. Together, these characteristics indicate that the dolomicrite in the study area was formed in a high-salinity, confined lake basin, characterized by low temperature, shallow burial, and rapid nucleation and crystallization. The dolomicrite experienced a contemporaneous period with formation of dark mudstone, shale and calcite, and a penecontemporaneous period with formation of dolomicrite via seepage-reflux and a diagenetic period when ferrodolomite was formed via burial.

Primary Pericardial Liposarcoma: The Role of Multi-Modality Imaging in the Diagnosis of a Pericardial Mass

Yang Fan,Wu Qian,Yan Yan,Zhang Zhang,Li Dong 아시아심장혈관영상의학회 2022 Cardiovascular Imaging Asia Vol.6 No.4

Primary pericardial liposarcomas are extremely rare. We presented a case of a 69-year-old man who presented with exertional dyspnea for more than one week. A pericardial mass was detected by echocardiography and then further investigated by computed tomography and cardiac magnetic resonance imaging. The tumor was resected completely, and the histopathological result was confirmed to be a well-differentiated liposarcoma.

Paeoniflorin treatment regulates TLR4/NF-κB signaling, reduces cerebral oxidative stress and improves white matter integrity in neonatal hypoxic brain injury

Yang, Fan,Li, Ya,Sheng, Xun,Liu, Yu The Korean Society of Pharmacology 2021 The Korean Journal of Physiology & Pharmacology Vol.25 No.2

Neonatal hypoxia/ischemia (H/I), injures white matter, results in neuronal loss, disturbs myelin formation, and neural network development. Neuroinflammation and oxidative stress have been reported in neonatal hypoxic brain injuries. We investigated whether Paeoniflorin treatment reduced H/I-induced inflammation and oxidative stress and improved white matter integrity in a neonatal rodent model. Seven-day old Sprague-Dawley pups were exposed to H/I. Paeoniflorin (6.25, 12.5, or 25 mg/kg body weight) was administered every day via oral gavage from postpartum day 3 (P3) to P14, and an hour before induction of H/I. Pups were sacrificed 24 h (P8) and 72 h (P10) following H/I. Paeoniflorin reduced the apoptosis of neurons and attenuated cerebral infarct volume. Elevated expression of cleaved caspase-3 and Bad were regulated. Paeoniflorin decreased oxidative stress by lowering levels of malondialdehyde and reactive oxygen species generation and while, and it enhanced glutathione content. Microglial activation and the TLR4/NF-κB signaling were significantly down-regulated. The degree of inflammatory mediators (interleukin 1β and tumor necrosis factor-α) were reduced. Paeoniflorin markedly prevented white matter injury via improving expression of myelin binding protein and increasing O1-positive olidgodendrocyte and O4-positive oligodendrocyte counts. The present investigation demonstrates the potent protective efficiency of paeoniflorin supplementation against H/I-induced brain injury by effectually preventing neuronal loss, microglial activation, and white matter injury via reducing oxidative stress and inflammatory pathways.