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RISS 인기검색어
- 검색키워드
- 저자 : Bo Yoon Seo (검색결과 438 건)
- 무료
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서영수,김용관,신동환,공보금,이정구,박정환,윤성환,정치영,이상경,김영훈 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.2
Objectives : This open prospective study was performed in order to evaluate the efficacy and extrapyramidal adverse effects of nemonapride in the schizophrenic patients, and was compared wit one of typical antipshchotics. haloperidol and one of atypical antipsychotics, risperidone. Methods : Thirty male and female schizophrenic patients(DSM-Ⅳ) were treated for 12 weeks with haloperidol(n=10), risperidone(n=10) and nemonapride(n=10). The overall efficacy was assessed at baseline, 1st week, 2nd week, 4th week, 8th week, and 12th week by the Positive and Negative Syndrome Scale for Schizophrenia(PANSS). Also the overall safety was assessed in the same time period by the Extrapyramidal Symptom Rating Scale(ESRS). Results : There were no significant differences in PANSS scores(total, positive, negative, and general psychopathology subscale) among haloperidol, risperidone, and nemonapride groups, Treatment responders, defined as at least 20% reduction of baseline total PANSS score, were achieved by 8 patients(80%) in haloperidol group, 10 patients(100%) in risperidone group, and 8 patients(80%) in nemonapride group. And there were no significant differences in ESRS total scores among haloperidol, risperidone, and nemonapride group. Inter-group comparison among haloperidol, risperidone and nemonapride group, as assessed by the ESRS, revealed no significant differences in the shifts to the maximum score, 9.4(±9.4), 6.2(±8.4), and 11.3(±8.1) respectively, and also revealed no significant differences in the mean time reaching the maximum score, 4.5(±4.5) week, 7.8(±4.8) week, and 4.6(±4.4) week, respectivily. Conclusion : There wee no significant differences in the efficacy and extrapyramidal adverse effects among haloperidal, rispecridone and nemonapride groups. These results suggest that nemonapride was as efficacious and safe in he treatment of schizophrenia, as well known and widely used antipsychotics, haloperidol and risperidone.
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The complete mitochondrial genome of Thrips palmi (Thysanoptera: Thripidae) in Korea
Bo Yoon Seo,Gwan-Seok Lee 한국응용곤충학회 2018 한국응용곤충학회 학술대회논문집 Vol.2018 No.10
오이총채벌레(Thrips palmi Karny)는 동남아시아지역이 원산으로 국내 침입 외래해충이다. 주로 노지와 하우스에서 재배되는 박과(Cucurbitaceae)와 가지과(Solanaceae) 작물에 직접 섭식과 바이러스 매개에 의한 피해가 크다. 본 연구에서는 차세대염기서열분석기술(NGS)을 통해 오이총채벌레의 미토콘드리아 전장 게놈을 해독하였으며 염기서열 신규 조립(de novo assembly) 결과 전체 길이가 16,414bp인 원형의 유전체로 추정되었다. 미토콘드리아 게놈 전체에서 뉴클레오티드는 A와 T가 78.5%를 차지는 특징을 보였다. 동물의 미토콘드리아 게놈에서 일반적으로 발견되는 37개 유전자 영역에 대해 BLAST 검색을 한 결과 trnV는 탐색되지 않았다. 본 발표에서는 신규 조립된 오이총채벌레 미토콘드리아 게놈 유전체에 포함된 유전자의 종류와 배열 등에 대한 기초 통계자료를 정리하였다.
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Female mate choice test of the brown planthopper (BPH) in the male-male competition-free conditions
Bo Yoon Seo,Jin Kyo Jung 한국응용곤충학회 2011 한국응용곤충학회 학술대회논문집 Vol.2011 No.10
In the previous study, the effect of orange-eyed color on mating of BPH was not clearly occurred, and the mating preference and multiple mating of female were cautiously suggested. To understand about the BPH female mate selection in the male-male competition-free conditions and the point of time for multiple mating, we designed four different combinations of the mate choice test with one virgin orange-eyed female (org/org) and two male BPH adults, orange-eyed male (org/org) and homozygous normal-eyed male (+/+). We gave the four different mating chances to female by the order of incubation (the first male and the following second male) and the incubation time (one day and days on end) of the second male. The distribution of the eye-color phenotype in F1 progeny and their hatching-order were observed in each mating combination. In the results, fourteen females out of twenty in four combinations produced progenies in accordance with mating chance priority of the first male, while three females of one combination selected the second male as a gamete. Interestingly, in three females of one combination with the continuous incubation of the second male, after eggs fertilized by the first male were continuously produced and then egg-laying was finished, progenies of the second male were started to be produced. From these results, it was suggested that mating order determines egg-laying order of female and the second mating of female would be occurred when sperm of the first male was almost exhausted in the reproductive organ.
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Bo Yoon Seo,Youn-Hee Kwon,김길하,정진교 한국응용곤충학회 2009 Journal of Asia-Pacific Entomology Vol.12 No.2
The stylet penetration behavior of Nilaparvata lugens (Hemiptera: Delphacidae) in rice plants (Oryza sativa)was evaluated through the use of an electrical penetration graph (EPG). To accomplish this, we classified theEPG signals into seven different waveforms, np, N1, N2, N3, N4-a, N4-b, and N5, according to their shapes,amplitudes, and frequencies. The N4-b waveform was always preceded by N3 and N4-a, in that order. Continuous honeydew excretion only occurred during the N4-b period, and the honeydew deposited on afilter paper containing ninhydrin reagent during the N4-b period was stained violet. The tips of the styletsthat were severed in the N3, N4-a, and N4-b periods were in the phloem region of rice. Moreover, the flow ofplant sap after stylectomy only occurred during the N4-b period. Finally, sucrose was the only carbohydratecomponent identified when HPLC analysis of the plant sap was conducted. On the other hand, honeydewexcretion hardly occurred during the N5 period and the tips of the stylets that were severed during the N5period were located in the xylem region of rice. Based on the location of the stylets and honeydew excretion,the EPG waveforms for the stylet penetration behaviors of N. lugens were assigned to the following groups;np: non-penetration of stylets, N1: penetration initiation, N2: salivation and stylet movement, N3: anextracellular activity near the phloem region, N4-a: an intracellular activity in phloem region, N4-b: phloemsap ingestion, and N5: activity in the xylem region
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An orange-eye mutant of the brown planthopper, Nilaparvata lugens (Hemiptera: Delphacidae)
Bo Yoon Seo,Jin Kyo Jung,Yeong-Tae Kim 한국응용곤충학회 2011 Journal of Asia-Pacific Entomology Vol.14 No.4
An orange-eye mutant of the brown planthopper (BPH), Nilaparvata lugens (Stål), was found in a green house and has since been maintained together with a normal-eye phenotype of BPH in an insectary. The orange color was expressed in all developmental stages of BPH: the eye spots of eggs and the eyes of nymphs and adults of both sexes and wing forms. Cross-mating results suggested that the inheritance of the orange-eye phenotype is controlled by a single autosomal recessive allele. The gene symbol related to this mutant was designated as “org”. Developmental duration and mortality of nymphal stages were not significantly different between the normal phenotype (homozygous and heterozygous) and the mutant. In addition, reproduction was not significantly different among mating combinations of the three BPH genotypes (+/+, +/org, org/org). The effect of eye color on mating of BPH was insignificant in a mate choice test which consisted of one orange-eye female, one orange-eye male, and one homozygous normal-eye male. Offspring produced by the orange-eye female BPH hatched and developed into adults normally, indicating that the eye color mutant found in this study is different from the red-eye BPH (Mochida, 1970) which showed the egg lethal effect in the red-eye BPH female
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Bo Yoon Seo,정진교,Byeong-Reol Choi,Hyung-Man Park,Si-Woo Lee,Bong Hoon Lee 한국응용곤충학회 2010 Journal of Asia-Pacific Entomology Vol.13 No.1
To understand the development of host plant resistance-breaking ability of the current BPH populations in Korea, we conducted nymphal survivorship tests and electrical penetration graph (EPG) studies on susceptible and resistant rice varieties with four different BPH populations, which were collected in the early 1980s (S-BPH) and in 2005, 2006, and 2007. The S-BPH had low survival rates on resistant rice varieties carrying either Bph1 or bph2. However, the current BPH populations have high resistance-breaking ability on the varieties with their elevated survival rates, whereas their survival rates were still low on the other resistant varieties, Gayabyeo (Bph1 the other unknown gene) and Rathu Heenati (Bph3). The EPG analysis also revealed that the ratio of BPH that could reach the phloem sap ingestion waveform (N4-b) within 15 h on the resistant rice varieties containing Bph1 or bph2 was higher in the current BPH populations (16.7–50%)than in the S-BPH population (0-4.2%). However, the pre-reaching time from the penetration start to the first N4-b waveform in the current BPH populations was significantly longer on resistant varieties (Bph1 or bph2)than on susceptible varieties. Furthermore, the total duration of N4-b waveform was significantly shorter on the resistant varieties. From these results, we suggest that, although the current BPHs collected in Korea have a high resistancebreaking ability through the increase of survival rate on resistant rice varieties carrying either Bph1 or bph2,they still have some difficulties feeding on the phloem sap of the resistant rice varieties.
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Mate choice test with eye color mutant of the brown planthopper, Nilaparvata lugens Stål
Bo Yoon Seo,Jin Kyo Jung 한국응용곤충학회 2011 한국응용곤충학회 학술대회논문집 Vol.2011 No.05
In the previous study, we found an orange-eyed mutant of the brown planthopper (BPH). And we confirmed that it’s orange phenotype is controlled by single recessive allele in the autosome. To understand the effect of the orange eye color on mating of BPH, we designed two different combinations of the mate choice test with three virgin female and male BPH adults. The one consisted of orange-eyed female (org/org), orange-eyed male (org/org), and homozygous normal-eyed male (+/+) (female mate choice). The other was composed of orange-eyed male (org/org), orange-eyed female (org/org), and homozygous normal-eyed female (+/+) (male mate choice). In female mate choice test, four mating types could be distinguished according to the distribution of the eye-color phenotype in F1 progeny and their hatching-order in each mating pair. Two mating types showed only one eye-color phenotype, normal and orange, respectively, and the other two produced both eye-color phenotypes in a different hatching-order. In male mate choice test, both phenotypes of offsprings were also produced in most mating pairs. From these results, the effect of eye color on mating of BPH was not clearly found, but the multiple mating in both sexes and the mating preference by female are cautiously suggested.
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