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RISS 인기검색어
- 검색키워드
- 저자 : Bo Ram Eo (검색결과 4 건)
- 무료
- 기관 내 무료
- 유료
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The effect of Saururus chinensis Baill against oxidative damage and inflammation
Hwang, Dong Ryeol,Jeong, Jin Boo,Eo, Hyun Ji,Hong, Se Chul,Yoo, Ji Hyun,Lee, Kun Hee,Kim, Bo Ram,Koo, Jin Suk The Korea Association of Herbology 2012 大韓本草學會誌 Vol.27 No.6
Objectives : ROS are involved in a wide spectrum of diseases including chronic inflammation and cancer. S.chinensis Baill, a perennial herb commonly called Chinese lizard's tail or Sam-baek-cho in Korea, is used for the treatment of edema and inflammatory diseases in the Oriental folk medicine. In this study, we investigated the antioxidant activities and anti-inflammatory effects of the two extracts, water(WE) and ethyl acetate(EAE) from S.chinensis Baill. Methods : Anti-oxidant activity was evaluated using Fe2+ chelating and hydroxyl radical scavenging assay. DNA cleavage assay, and western blot and immunostaining for phospho-p65 were performed to evaluate anti-oxidative effect. Anti-inflammatory effect was performed using NO generation assay and western blot in LPS-stimulated RAW264.7 cell. Results : In Fe2+ chelating activity and hydroxyl radical scavenging activity, WE showed more strong scavenging activity for hydroxyl radical than EAE. WE scavenged hydroxyl radical by 12% at 3.2 ${\mu}g/ml$, 21% at 16 ${\mu}g/ml$, 32% at 80 ${\mu}g/ml$, 66% at 400 ${\mu}g/ml$ and 82% at 2000 ${\mu}g/ml$, respectively. In addition, WE showed more strong chelating activity than EAE. WE chelated Fe2+ ion by 1.1% at 3.2 ${\mu}g/ml$, 8.2% at 16 ${\mu}g/ml$, 26.3% at 80 ${\mu}g/ml$, 72% at 400 ${\mu}g/ml$ and 89% at 2000 ${\mu}g/ml$, respectively. Also, WE inhibited oxidative damage via its anti-oxidant activity. In anti-inflammatory effect, EAE inhibited NO production and iNOS expression. In addition EAE suppressed the NF-${\kappa}B$ and MAPK signaling pathway in LPS-stimulated RAW 264.7 cells. Conclusions : Together, these data indicate that S. chinensis Baill, shows anti-oxidant activity and anti-inflammatory effect.
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맥켄지/윌리엄 운동이 과체중 요통환자의 요통과 과체중에 미치는 영향
AhReum Lee,Han Suk Jung,Bo Ram Eo 한서대학교 보완대체의학연구소 2016 Research Journal of Complementary and Alternative Vol.- No.7
Due to rapid changes in the modern civilized society, there is a growing interest in the reduction of physical labor and the improvement of health. For the last few of decades, the prevalence of obesity has been continually on the rise. Overseas studies on obesity-related risk factors suggested that obesity could lead to backache-related diseases. The backache is the most common musculo-skeletal disease among people of all ages, classes and vocations, and might result in excessive costs on a socio-economic front. In this fact-finding survey, this study examined the relation between pain intensity, muscle strength, and weight loss, when William exercise, McKenzie exercise, and aerobic exercise were applied as a regimen for Korean adults who suffered from abdominal obesity and backache. After selecting a total of 60 male and female adults as an experiment group, their individual BMIs were measured to classify the study participants into overweight, obese and severe obese groups, and their personal information such as gender, physical profiles and vocations were analyzed. An analysis was conducted based on the self-administered questionnaire answers including the occurrence cases and periods of backache, treatment types, treatment periods, exercise periods, and sedentary times on chairs and in front of computers. A 12-week intensive exercise program which required the participants to do the regular exercise regimen for one hour three times per week (a ‘Mon/Wed/Fri’ team or a ‘Tue/Thur/Sat’ team), and the participants’ physical changes were measured when the 12-week program is finished. In the trends of soaring job stress and musculoskeletal disorder, it can be said that they affect not only one of the problems but also the physical and mental health problems in care worker. The problem of service mentality can be a triggered, so it is important to find a solution for the health in care worker.
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Alteration in Self-Awareness of “Stiff Neck” under Chiropractic Care
Kazuya Tabata,Hiromitsu Ikeguchi,Minae Amano,Jin Ok Choi,Bo Ram Eo 한서대학교 보완대체의학연구소 2012 Research Journal of Complementary and Alternative Vol.- No.3
Our research pertains to how much change occurs to the subjective symptoms of patients who had been treated with chiropractic care. In this research, we have given chiropractic care to 100 patients - male and female, who had been undergoing “stiff neck” as a subjective symptom - and received valid result s from 91 of them. After treating them with chiropractic adjustments only once or twice, changes in the Pain Scale(PS) of their subjective symptoms was seen in 90% of the patients. We have concluded that chiropractic care had been an effective treatment for the improvement of subjective symptom as “stiff neck”. The average score of improvement in PS was 2.1.
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The effect of Saururus chinensis Baill against oxidative damage and inflammation
Dong Ryeol Hwang,Jin Boo Jeong,Hyun Ji Eo,Se Chul Hong,Ji Hyun Yoo,Kun Hee Lee,Bo Ram Kim,Jin Suk Koo 대한본초학회 2012 大韓本草學會誌 Vol.27 No.6
Objectives: ROS are involved in a wide spectrum of diseases including chronic inflammation and cancer. S.chinensis Baill, a perennial herb commonly called Chinese lizard's tail or Sam-baek-cho in Korea, is used for the treatment of edema and inflammatory diseases in the Oriental folk medicine. In this study, we investigated the antioxidant activities and anti-inflammatory effects of the two extracts, water (WE) and ethyl acetate (EAE) from S.chinensis Baill. Methods: Anti-oxidant activity was evaluated using Fe2+ chelating and hydroxyl radical scavenging assay. DNA cleavage assay, and western blot and immunostaining for phospho-p65 were performed to evaluate anti-oxidative effect. Anti-inflammatory effect was performed using NO generation assay and western blot in LPS-stimulated RAW264.7 cell. Results: In Fe2+ chelating activity and hydroxyl radical scavenging activity, WE showed more strong scavenging activity for hydroxyl radical than EAE. WE scavenged hydroxyl radical by 12% at 3.2 ㎍/ml, 21% at 16 ㎍/ml, 32% at 80 ㎍/ml, 66% at 400 ㎍/ml and 82% at 2000 ㎍/ml, respectively. In addition, WE showed more strong chelating activity than EAE. WE chelated Fe2+ ion by 1.1% at 3.2 ㎍/ml, 8.2% at 16 ㎍/ml, 26.3% at 80 ㎍/ml, 72% at 400 ㎍/ml and 89% at 2000 ㎍/ml, respectively. Also, WE inhibited oxidative damage via its anti-oxidant activity. In anti-inflammatory effect, EAE inhibited NO production and iNOS expression. In addition EAE suppressed the NF-κB and MAPK signaling pathway in LPS-stimulated RAW 264.7 cells. Conclusions: Together, these data indicate that S. chinensis Baill, shows anti-oxidant activity and anti-inflammatory effect.
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