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Yan-Bin Zhang,Fu-Quan Chen,Yu-Jian Lin,Hao-Biao Chen 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.4
Inverted T-type retaining walls are commonly used in subgrade or slope support engineering, which inevitably satisfies a narrow backfill. Using the classical earth pressure calculation method in a narrow-backfill case causes an inevitable error. The current narrow-backfill earth pressure theory does not apply to inverted T-type retaining walls. In this study, the failure mechanism in a narrow backfill when the inverted T-type retaining wall rotates about the heel is investigated using adaptive finite element analysis method. Numerical analysis reveals multiple sliding surfaces. A theoretical model for calculating earth pressure using difference and limit equilibrium methods is proposed. The proposed model is suitable for more complex conditions, including narrow backfill, irregular ground, and non-uniform overload, than previous models. Parameter analysis reveals that the cross-sectional area of the plastic zone and active earth pressure have a positive correlation. Further, the interface friction influences the decrease in active earth pressure. Fitting formulas for assessing the cases of long and short heel and the critical size of backfill width are presented to facilitate practitioners to evaluate the backfill.
Hydrogels with diffusion-facilitated porous network for improved adsorption performance
Yan-yan Pei,Dong-mei Guo,Qing-da An,Zuo-yi Xiao,Shangru Zhai,Bin Zhai 한국화학공학회 2018 Korean Journal of Chemical Engineering Vol.35 No.12
Porous alginate-based hydrogel beads (porous ABH) have been prepared through a facile and sustainable template-assisted method using nano-calcium carbonate and nano-CaCO3 as pore-directing agent for the efficient capture of methylene blue (MB). The materials were characterized by various techniques. The sorption capacities of ABH towards MB were compared with pure sodium alginate (ABH-1:0) in batch and fixed-bed column adsorption studies. The obtained adsorbent (ABH-1:3) has a higher BET surface area and a smaller average pore diameter. The maximum adsorption capacity of ABH-1:3 obtained from Langmuir model was as high as 1,426.0mg g1. The kinetics strictly followed pseudo-second order rate equation and the adsorption reaction was effectively facilitated, approximately 50minutes to achieve adsorption equilibrium, which was significantly shorter than that of ABH-1:0. The thermodynamic parameters revealed that the adsorption was spontaneous and exothermic. Thomas model fitted well with the breakthrough curves and could describe the dynamic behavior of the column. More significantly, the uptake capacity of ABH-1:3 was still higher than 75% of the maximum adsorption capacity even after ten cycles, indicating that this novel adsorbent can be a promising adsorptive material for removal of MB from aqueous solution under batch and continuous systems.
Yan Bin,Li Xurui,Peng Mou,Zuo Yali,Wang Yinhuai,Liu Pian,Ren Weigang,Jinxin Liu 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Aberrant glucose metabolism is a characteristic of bladder cancer. Hyperglycemia contributes to the development and progression of bladder cancer. However, the underlying mechanism by which hyperglycemia promotes the aggressiveness of cancers, especially bladder cancer, is still incompletely understood. N6-methyladenosine (m6A) modification is a kind of methylation modification occurring at the N6 position of adenosine that is important for the pathogenesis of urological tumors. Recently, it was found that the m6A reader YTHDC1 is regulated by high-glucose conditions. In our study, we revealed that YTHDC1 is not only regulated by high-glucose conditions but is also downregulated in bladder cancer tissue and associated with the prognosis of cancer. We also showed that YTHDC1 suppresses the malignant progression of and the glycolytic process in bladder cancer cells in an m6A-dependent manner and determined that this effect is partially mediated by GLUT3. Moreover, GLUT3 was found to destabilize YTHDC1 by upregulating RNF183 expression. In summary, we identified a novel YTHDC1/GLUT3/RNF183 feedback loop that regulates disease progression and glucose metabolism in bladder cancer. Collectively, this study provides new insight regarding the pathogenesis of bladder cancer under hyperglycemic conditions and might reveal ideal candidates for the development of drugs for bladder cancer.
( Bin Yin ),( Chen Xi Hu ),( Zheng Chen ),( Wen Jun Zhao ),( Li Rong Wei ),( Yan Wen Zheng ),( Chao He ),( Yan Zeng ) 한국응용약물학회 2014 Biomolecules & Therapeutics(구 응용약물학회지) Vol.22 No.2
Vesicular Stomatitis Virus G Glycoprotein and ATRA EnhancedBystander Killing of Chemoresistant Leukemic Cells by HerpesSimplex Virus Thymidine Kinase/Ganciclovir
Bin Zhou,Zhi-Bin Yan,Guang-Ren Duan 제어·로봇·시스템학회 2010 International Journal of Control, Automation, and Vol.8 No.1
The polynomial Diophantine matrix equation and the generalized Sylvester matrix equation are important for controller design in frequency domain linear system theory and time domain linear system theory, respectively. By using the so-called generalized Sylvester mapping, right coprime factorization and Bezout identity associated with certain polynomial matrices, we present in this note a unified parametrization for the solutions to both of these two classes of matrix equations. Moreover, it is shown that solutions to the generalized Sylvester matrix equation can be obtained if solutions to the Diophantine matrix equation are available. The results disclose a relationship between the polynomial Diophantine matrix equation and generalized Sylvester matrix equation that are respectively studied and used in frequency domain linear system theory and time domain linear system theory.
Failure Mode, Effects and Criticality Analysis of Remanufactured Machine Tools in Service
Yan-bin Du,Lan Liao,Le-su Wang 한국정밀공학회 2017 International Journal of Precision Engineering and Vol.18 No.3
Failure Mode, Effects and Criticality Analysis (FMECA) of remanufactured machine tools is one of the key issues for improving their quality and reliability. According to the characteristics of remanufactured machine tools and the basic principle of FMECA, the method of failure mode analysis for remanufactured machine tools in service is proposed, with the FMECA procedure being expounded in detail. In addition, failure criticality of each failure mode for remanufactured machine tools is analyzed by risk priority number (RPN) method. Finally, the method is demonstrated in a case study of remanufactured YX3120 gear hobbing machine. The results from the case study are discussed and conclusions are drawn.
Root Welding of V-Groove Thick Plate without Backing Plate by MAG-TIG Double-Arc Welding
Yan-Bin Zhou,Disheng Fang,Li-Ming Liu 한국정밀공학회 2017 International Journal of Precision Engineering and Vol.18 No.4
MAG-TIG (metal active gas-Tungsten inert gas) double-arc welding process is applied to make stable back beads in the first layer during one-side multilayer welding without backing plate. To explain the reason why stable back beads can be formed, a comparison was made between single MAG welding and MAG-TIG double-arc welding. Results indicated that during the optimized condition in MAG-TIG double-arc welding, about one-third heat energy of the heat source acts on the root face, and about two-third heat energy acts on the molten pool. The distribution of temperature and surface tension in the molten pool must be more balanced and reasonable, in order to obtain the ideal back weld bead formation. This process is a new welding process giving high quality and efficiency in root welding of thick plate.