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- 저자 : Peng Mou (검색결과 3 건)
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A Study on Safety Injury Risks of Marathon Participants in China from a Legal Perspective
김정석,한슈오,Peng Zhaoxin,Mou Ning 한국경호경비학회 2023 시큐리티연구 Vol.- No.75
This paper explores the legal considerations surrounding personal injury in marathon racing events in China, with a focus on participant safety and minimizing legal liabilities, for Korea, who shares a similar interest in marathon racing as popular sporting events, and also hosts numerous marathon events, attracting participants from all over the world, to benefit from valuable insights to make continuous improvement of marathon events in Korea, ensure a safer and more enjoyable experience for all participants, and promote local tourism image. It emphasizes the significance of adhering to legal and regulatory requirements, securing necessary permits and approvals, developing emergency response plans, and collaborating with government authorities for effective security coordination. The paper employs the legal analysis framework, utilizes the research method of case study, and outlines the lessons learned from three cases, emphasizing compliance, safety measures, and eligibility checks. Through discussion, organizers are advised to implement strict safety protocols, conduct thorough eligibility checks, provide comprehensive information and warnings, obtain appropriate insurance coverage, and hire experienced staff, to mitigate legal risks. Participants are also encouraged to assess event risks, prioritize personal safety, and understand the safety measures implemented by organizers. The paper concludes the importance of prioritizing safety and offers guidance for reducing legal liabilities in marathon racing events through adherence to regulations, safety protocols, and collaboration with relevant authorities.
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Yan Bin,Li Xurui,Peng Mou,Zuo Yali,Wang Yinhuai,Liu Pian,Ren Weigang,Jinxin Liu 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-
Aberrant glucose metabolism is a characteristic of bladder cancer. Hyperglycemia contributes to the development and progression of bladder cancer. However, the underlying mechanism by which hyperglycemia promotes the aggressiveness of cancers, especially bladder cancer, is still incompletely understood. N6-methyladenosine (m6A) modification is a kind of methylation modification occurring at the N6 position of adenosine that is important for the pathogenesis of urological tumors. Recently, it was found that the m6A reader YTHDC1 is regulated by high-glucose conditions. In our study, we revealed that YTHDC1 is not only regulated by high-glucose conditions but is also downregulated in bladder cancer tissue and associated with the prognosis of cancer. We also showed that YTHDC1 suppresses the malignant progression of and the glycolytic process in bladder cancer cells in an m6A-dependent manner and determined that this effect is partially mediated by GLUT3. Moreover, GLUT3 was found to destabilize YTHDC1 by upregulating RNF183 expression. In summary, we identified a novel YTHDC1/GLUT3/RNF183 feedback loop that regulates disease progression and glucose metabolism in bladder cancer. Collectively, this study provides new insight regarding the pathogenesis of bladder cancer under hyperglycemic conditions and might reveal ideal candidates for the development of drugs for bladder cancer.
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Huanxiong Xia,Dong Xiang,Peng Mou 대한기계학회 2015 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.29 No.2
The process chamber is the core unit of chamber-category integrated circuit manufacturing equipment. The physical field distributionin the chamber directly determines the process quality, but flexible and refined regulation of the physical field is the severest difficultythe equipment design confronts. The actual process chamber is relatively rigid in general, and lacks enough degrees of freedom (DOF) toflexibly regulate the distribution of process factors. As a result, it is difficult to achieve refined regulation of the process quality of thelarge-area wafer. To solve this problem, a multi-DOF and flexible design concept for the spatial distribution of process factors was proposed,and based on this concept, two typical design solutions were presented. To solve this kind of high-DOF and physical field involveddesign problem, a generalized profile error feedback (PEF) method was established that employs an iterative-approximation modeand starts from an initial guessed model. Four operations, including error obtainment, weight matrix configuration, error distribution andcompensation, are in each iteration step. This iterative loop is run to make the current physical field profile in the critical domain continuouslyapproximate the expected profile. The two design solutions both achieved the flexible and refined regulation of the thermal fieldvia the PEF method. And under the condition of model-based simulation, the PEF method drove the current temperature profile to approximatethe expected one in the chamber, and found a design variables sequence to make the relative error reduce from 2.91~5.28% ofthe initial guessed model to 0.012~0.015%.
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