Quantitative Assessment on the Variation of Compressibility of Wenzhou Marine Clay During Destructuration

Xia Bian,Jian-Wen Ding,Jian Shi,Sen Qian 대한토목학회 2017 KSCE JOURNAL OF CIVIL ENGINEERING Vol.21 No.3

A series of oedometer test were performed on both undisturbed and remolded specimens of Wenzhou marine clay to quantitatively investigate the degradation of soil structure during compression. The laboratory tests show that the swell index of both natural and remolded Wenzhou marine clay increase with the increase in consolidation stress. Hence, the normalizing parameter ‘swell sensitivity’, termed as the ratio of the remolded to the natural swelling index, can only be regarded as a qualitative parameter. On the other hand, the normalized stress sensitivity has a good parabolic relationship with the consolidation stress during destructuration. This result indicates that the stress sensitivity can be used as a quantitative interpretation of the degradation of soil structure for natural Wenzhou marine clay. Comparison between stress sensitivity and additional void ratio during destructuration shows that the variation of soil structure during destructuration represented by stress sensitivity and additional void ratio are essentially the same. In addition, the parameter used in formulating the variation of stress sensitivity with the stress level is correlated with natural void ratio and void ratio at liquid limit.

EXISTENCE OF SOLUTION FOR A FRACTIONAL DIFFERENTIAL INCLUSION VIA NONSMOOTH CRITICAL POINT THEORY

YANG, BIAN-XIA,SUN, HONG-RUI The Kangwon-Kyungki Mathematical Society 2015 한국수학논문집 Vol.23 No.4

This paper is concerned with the existence of solutions to the following fractional differential inclusion $$\{-{\frac{d}{dx}}\(p_0D^{-{\beta}}_x(u^{\prime}(x)))+q_xD^{-{\beta}}_1(u^{\prime}(x))\){\in}{\partial}F_u(x,u),\;x{\in}(0,1),\\u(0)=u(1)=0,$$ where $_0D^{-{\beta}}_x$ and $_xD^{-{\beta}}_1$ are left and right Riemann-Liouville fractional integrals of order ${\beta}{\in}(0,1)$ respectively, 0 < p = 1 - q < 1 and $F:[0,1]{\times}{\mathbb{R}}{\rightarrow}{\mathbb{R}}$ is locally Lipschitz with respect to the second variable. Due to the general assumption on the constants p and q, the problem does not have a variational structure. Despite that, here we study it combining with an iterative technique and nonsmooth critical point theory, we obtain an existence result for the above problem under suitable assumptions. The result extends some corresponding results in the literatures.

Deformable Liposomes for Topical Skin Delivery of Arbutin

Bian, Sheng-Jie,Choi, Min-Koo,Lin, Hong-Xia,Chung, Suk-Jae,Shim, Chang-Koo,Kim, Dae-Duk,Zheng, Jun-Min 한국약제학회 2006 Journal of Pharmaceutical Investigation Vol.36 No.5

Overcoming the thickness paradox: Systematical optimization of inverted polymer solar cells

Xinyuan Xia,Zuqiang Bian,Chunhui Huang 한국물리학회 2015 Current Applied Physics Vol.15 No.11

Inverted structure comes out to be a promising alternative for making polymer solar cells (PSC) with high efficiency and long-term stability. Vertically stacked functional layers with planar shapes often suffer contradictions in holding high optical absorption and excellent charge transfer/hindrance capability to construct well performed inverted PSC devices. Here, we give an example of rational control of the thickness of electron transport layer (ETL), hole transport layer (HTL) and organic active layer (OAL) to achieve a synergistic effect on promoting the overall photovoltaic behaviors. With in-depth exploration of the interaction between device performance and layer thickness, we obtain the optimized device ITO/ ZnO Ncs (45 nm)/P3HT:PCBM (70 nm)/MoO3 (1 nm)/Ag (70 nm) exhibiting an Voc of 0.63 V, Jsc of 12.52 mA/cm2, FF of 54% and PCE of 4.26%.

Biological and Chemical Microsensors for Health Care and Environment Monitoring

Shanhong Xia,Chao Bian,Qiannan Xue,Jizhou Sun,Qingyong Chen 대한전자공학회 2009 ITC-CSCC :International Technical Conference on Ci Vol.2009 No.7

This paper presents several biological and chemical microsensors developed based on micro and nano technologies for the applications of health care and environment monitoring, including micro amperometric biosensor, micro potentiometric immunosensor and micro gas sensor and so on. The electroactivities of the micro amperometric biosensor with three-dimensional microelectrodes was enhanced obviously with the help of the nano- and microstructures. By introducing nanoparticles with seed mediated growth method, the sensitivity of the micro potentiometric immunosensor for %HbA1c has been increased. A micro pellistor with nanoporous alumina catalyst carrier have been constructed for detecting combustible gas below the lower explosive limit, which shows advantages of low power comsumption, good thermal performance and easy fabrication.

Curdione Inhibits Proliferation of MCF-7 Cells by Inducing Apoptosis

Li, Juan,Bian, Wei-He,Wan, Juan,Zhou, Jing,Lin, Yan,Wang, Ji-Rong,Wang, Zhao-Xia,Shen, Qun,Wang, Ke-Ming Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22

Background: Curdione, one of the major components of Curcuma zedoaria, has been reported to possess various biological activities. It thus might be a candidate anti-flammatory and cancer chemopreventive agent. However, the precise molecular mechanisms of action of curdione on cancer cells are still unclear. In this study, we investigated the effect of curdione on breast cancer. Materials and Methods: Xenograft nude mice were used to detect the effect of curdione on breast cancer in vivo; we also tested the effect of curdione on breast cancer in vitro by MTT, Flow cytometry, JC-I assay, and western blot. Results: Firstly, we found that curdione significantly suppressed tumor growth in a xenograft nude mouse breast tumor model in a dose-dependent manner. In addition, curdione treatment inhibited cell proliferation and induced cell apoptosis. Moreover, after curdione treatment, increase of impaired mitochondrial membrane potential occurred in a concentration dependent manner. Furthermore, the expression of apoptosis-related proteins including cleaved caspase-3, caspase-9 and Bax was increased in curdione treatment groups, while the expression of the anti-apoptotic Bcl-2 was decreased. Inhibitors of caspase-3 were used to confirm that curdione induced apoptosis. Conclusions: Overall, our observations first suggested that curdione inhibited the proliferation of breast cancer cells by inducing apoptosis. These results might provide some molecular basis for the anti-cancer activity of curdione.

Mechanical Properties and Damage Characteristics of Coal-Rock Combination with Different Dip Angles

Zhi-Guo Xia,Shuai Liu,Zhuang Bian,Jinhu Song,Fan Feng,Ning Jiang 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.5

The effect of the dip angle of an interlayer coal seam on rock mass mechanical behavior and damage characteristics is seldom discussed. To address the lack of the existing research, a numerical simulation was conducted using the Particle Flow Code (PFC2D), and its damage to mechanical behavior, acoustic emission (AE) characteristics, and damage characteristics were analyzed. The outcomes exhibit the peak strength and elastic modulus of coal-rock combinations are between that of rock and coal. As the coal inclination angle rises, the elastic modulus and peak strength gradually decrease. AE model experiences the initial growth period, stable growth period, and rapid decline period. The value of AE hits and the generation of the AE signal is affected by the size of the inclination angle. The degree of damage to the coal-rock combination gradually rises as the angle rises. The damage process of the coal and rock composite sample encompasses an initial damage phase, damage stable evolution phase, accelerated damage phase, and a failure phase. The damage values of the stable evolution stage for varying dip angle models are also different. As the inclination angle increases, the damage value gradually increases, while the strain at the same damage value gradually decreases.

Effect of Clogging on Large Strain Consolidation with Prefabricated Vertical Drains by Vacuum Pressure

Yupeng Cao,Jianwen Xu,Xia Bian,Guizhong Xu 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.10

Clogging will inevitably occur while using vacuum preloading method to process super-soft soils with high water content. How to quantitatively evaluate the effect of clogging on the consolidation behavior is a key issue to be solved. Based on NALSC (negative axisymmetric large-strain consolidation) model, considering the “internal clogging” and the “external clogging”, a calculation method by using parameter “clogging rate” to reflect clogging problem is proposed for single-well consolidation theory. Effects of clogging rate and clogging occurred time on Us (degree of consolidation defined by strain) and Up (degree of consolidation defined by stress) are investigated. Differences of the effect of clogging on consolidation degree are determined between large-strain and small-strain consolidation theory. The results show that, the larger the clogging rate, the smaller the degree of consolidation of the soil at the same consolidation time. Effect of clogging on Up is greater than Us. The earlier the clogging occurs, the smaller the degree of consolidation at the same clogging rate. Influences on the degree of consolidation for large-strain and small-strain theory are the same. Consolidation rate of soil is determined to a certain extent by the “generalized clogging parameter μ”. The “external clogging” has a greater influence on the degree of consolidation than the “internal clogging” at the same clogging rate.

Variation of magnetic properties with different annealed temperatures in the Ni_3[Fe(CN)_6]_2ㆍXH_2O

M. Liu,X.F. Bian,Y.F. Xia,Z. Bao,H.S. Wu,M.X. Xu 한국물리학회 2011 Current Applied Physics Vol.11 No.3

Molecular magnet nickel(II) hexacyanoferrate(III) powder Ni_3[Fe(CN)_6]_2ㆍXH_2O was prepared by coprecipitation method. The coprecipitated powder was annealed in vacuum at different temperatures of 140,and 160 ℃. Water molecules contained in Prussian blue analogues were removed by heating. The annealing of Ni^II ferricyanide induced an inner charge transfer from Ni^II towards Fe^III to form the mixed valence system Ni(II) Ni(III) ferri-ferro-cyanide. Variation of magnetic properties with different annealed temperatures was studied by elemental analysis, powder X-ray diffraction, transmission electron microscopy, Fourier transform infrared, and Mössbauer and magnetization measurements. The differences in magnetic phase transition temperature, coercivity, remanence and effective magnetization are studied. Differences in magnetic properties may be attributed to a partial charge transfer from Ni^II to Fe^III.

Culture of a Whole Porcine Liver Ex Situ without Red Blood Cells

( Jing Dong ),( Lingling Xia ),( Hefang Shen ),( Congwen Bian ),( Sujin Bao ),( Ming Zhang ),( Yan Dai ),( Yanhong Xu ),( Qiru Xiong ),( Jianjian Xu ),( Lili Xu ) 대한간학회 2018 춘·추계 학술대회 (KASL) Vol.2018 No.1

Aims: Liver transplantation is an effective approach to end-stage liver disease. Shortage of donor liver and increased waiting time for liver transplantation necessitate the development of an organ culture system by which livers can be cultured and maintained ex situ for a prolonged period of time. The aim of this work is to test whether cell culture condition in vitro could be used to culture whole livers ex situ without the use of erythrocytes. Methods: Eight castrated male land race/farm young porcine livers were exposed to 30 min warm ischemia and 30 min cold perfusion. Livers were isolated and connected to an ex situ liver culture system using a standard culture medium RPMI 1640 supplied with 10% of fetal calf serum and sufficient dissolved oxygen under a normothermic condition for 6 hours. Metabolic biomarkers, bile and urea production, hepatic cell viability, and histology analysis of biopsies were performed and analyzed. Results: Dissociated porcine hepatic cells survived and grew in vitro under the standard RPMI 1640 culture medium. When the same RPMI 1640 medium supplemented with 10% of FCS and sufficient oxygen was used to culture livers ex situ, over 98% of liver cells were viable for at least 6 hours during ex situ whole organ culture based on the results from biochemical assays. Conclusions: Our data demonstrate that the liver culture system established in this work can be used to culture whole livers ex situ in the absence of erythrocytes.