The Ropeless Elevator: New Transportation System for High-rise Buildings (and Beyond)

Belmonte, Martina,Trabucco, Dario Council on Tall Building and Urban Habitat Korea 2021 International journal of high-rise buildings Vol.10 No.1

The paper reports the result of a 2-year long research conducted by CTBUH on the design possibilities enabled by the Ropeless and Multidirectional elevator systems, investigating how such a significant innovation (or better to say revolution) in the vertical transportation could affect tall buildings first and cities then. The purpose of the study is to prefigure the adoption of ropeless and multidirectional cabins for tall buildings mobility, with the aim to overcome the evolutionary bottleneck of the high-rise building type due to the exclusively vertical direction of transport, which limited, over the years, the design possibilities in terms of height, shape and relations with the surrounding environment. CTBUH research team, together with professionals in the field and supporting academic advisors, developed a series of design considerations on plan organizations, dispatching alternatives and on the integration of horizontal direction in the circulation, with the aim of anticipating potential and criticality arising from the application of ropeless and multidirectional systems.

The acceptance of nuclear energy as an alternative source of energy among Generation Z in the Philippines: An extended theory of planned behavior approach

Belmonte Zachariah John A.,Prasetyo Yogi Tri,Benito Omar Paolo,Liao Jui-Hao,Susanto Krisna Chandra,Young Michael Nayat,Persada Satria Fadil,Nadlifatin Reny 한국원자력학회 2023 Nuclear Engineering and Technology Vol.55 No.8

Nuclear Power Plants (NPP) are widely utilized around the globe from different base forms as it is one of the most dependable renewable resources that technological advancements have offered. However, different perceptions of the usage of NPPs emerged from different generations. The purpose of this study was to investigate the acceptance of nuclear energy as an alternative source of energy among Generation Z in the Philippines by utilizing an extended Theory of Planned Behavior (TPB) approach. An online questionnaire which consisted of 31 items was distributed using a purposive sampling approach and 450 respondents of Generation Z voluntarily answered. Structural Equation Modeling (SEM) showed that the knowledge regarding NPP had significant effects on risk perception and benefit perception which subsequently led to subjective norms. In addition, perceived behavioral control and subjective norms had significant effects on behavioral intention which led to nuclear acceptance. Interestingly, the respondents perceived the benefit of NPP as slightly higher than the perceived risk. With these, it was clear that the commissioning Nuclear Power Plant must consider as an alternative source of electric energy in the Philippines. Moreover, this study is one of the first studies that investigated the acceptance of NPP among Generation Z. Lastly, the model could be a basis to strengthen the acceptance strategy of opening NPP among Generation Z, particularly in developing countries.

Healthcare Information Technology: A Systematic Mapping Study

Enrique Maldonado Belmonte,Salvador Otón Tortosa,Luis de-Marcos Ortega,José-María Gutiérrez-Martínez 대한의료정보학회 2023 Healthcare Informatics Research Vol.29 No.1

Objectives: This paper presents a systematic mapping of studies related to information systems and technology in the field ofhealthcare, enabling a visual mapping of the different lines of knowledge that can provide an overview of the scientific literaturein this field. This map can help to clarify critical aspects of healthcare informatics, such as the main types of informationsystems, the ways in which they integrate with each other, and the technological trends in this field. Methods: Systematicmapping refers to a process of classifying information in a given area of knowledge. It provides an overview of the state of theart in a particular discipline or area of knowledge, establishing a map that describes how knowledge is structured in that particulararea. In this study, we proposed and carried out a specific implementation of the methodology for mapping. In total,1,619 studies that combine knowledge related to information systems, computer science, and healthcare were selected andcompiled from prestigious publications. Results: The results established a distribution of the available literature and identifiedpapers related to certain research questions, thereby providing a map of knowledge that structures the different trendsand main areas of research, making it possible to address the research questions and serving as a guide to deepen specific aspectsof the field of study. Conclusions: We project and propose future research for the trends that stand out because of theirinterest and the possibility of exploring these topics in greater depth.

Perimeter leakage current in polymer light emitting diodes

Germà Garcia-Belmonte,José M. Montero,Yassid Ayyad-Limonge,Eva M. Barea,Juan Bisquert,Henk J. Bolink 한국물리학회 2009 Current Applied Physics Vol.9 No.3

Observation of leakage current paths through the device perimeter in standard poly(phenylene vinylene)-based light-emitting devices is reported. Perimeter leakage currents govern the diode performance in reverse and low positive bias and exhibit an ohmic character. Current density correlates with the perimeter-to-area ratio thus indicating that leakage currents are mainly confined on polymer regions in the vicinity of metallic contact limits (device perimeter). Observation of leakage current paths through the device perimeter in standard poly(phenylene vinylene)-based light-emitting devices is reported. Perimeter leakage currents govern the diode performance in reverse and low positive bias and exhibit an ohmic character. Current density correlates with the perimeter-to-area ratio thus indicating that leakage currents are mainly confined on polymer regions in the vicinity of metallic contact limits (device perimeter).

Pluripotency of male germline stem cells

Kim, Sungtae,Belmonte, Juan Carlos Izpisua Springer-Verlag 2011 Molecules and cells Vol.32 No.2

Role of Local Chemical Potential of Cu on Data Retention Properties of Cu-Based Conductive-Bridge RAM

Jiyong Woo,Belmonte, Attilio,Redolfi, Augusto,Hyunsang Hwang,Jurczak, Malgorzata,Goux, Ludovic IEEE 2016 IEEE electron device letters Vol.37 No.2

<P>In this letter, we experimentally investigate data retention in a copper (Cu)-based conductive bridge random-access memory device at a low current regime (10 mu A) in which retention is governed by factors other than just the conductive filament. Our findings show that the retention characteristics are determined by the local chemical potential of Cu between the conductive filament and its surrounding medium. Furthermore, the retention tendencies are described by the electrochemical reaction in accordance with the potential difference of Cu ions. Therefore, an appropriate quantity of Cu ions around the filament is important for achieving thermally reliable high and low resistance states over time.</P>

Effect of combined mulberry leaf and fruit extract on liver and skin cholesterol transporters in high fat diet-induced obese mice

Giuseppe Valacchi,Giuseppe Belmonte,Clelia Miracco,Hyeyoon Eo,Yunsook Lim 한국영양학회 2014 Nutrition Research and Practice Vol.8 No.1

Obesity is an epidemic disease characterized by an increased inflammatory state and chronic oxidative stress with high levels of pro-inflammatory cytokines and lipid peroxidation. Moreover, obesity alters cholesterol metabolism with increases in low-density lipoprotein (LDL) cholesterols and triglycerides and decreases in high-density lipoprotein (HDL) cholesterols. It has been shown that mulberry leaf and fruit ameliorated hyperglycemic and hyperlipidemic conditions in obese and diabetic subjects. We hypothesized that supplementation with mulberry leaf combined with mulberry fruit (MLFE) ameliorate cholesterol transfer proteins accompanied by reduction of oxidative stress in the high fat diet induced obesity. Mice were fed control diet (CON) or high fat diet (HF) for 9 weeks. After obesity was induced, the mice were administered either the HF or the HF with combination of equal amount of mulberry leaf and fruit extract (MLFE) at 500mg/kg/day by gavage for 12 weeks. MLFE treatment ameliorated HF induced oxidative stress demonstrated by 4-hydroxynonenal (4-HNE) and modulated the expression of 2 key proteins involved in cholesterol transfer such as scavenger receptor class B type 1 (SR-B1) and ATP-binding cassette transporter A1 (ABCA1) in the HF treated animals. This effect was mainly noted in liver tissue rather than in cutaneous tissue. Collectively, this study demonstrated that MLFE treatment has beneficial effects on the modulation of high fat diet-induced oxidative stress and on the regulation of cholesterol transporters. These results suggest that MLFE might be a beneficial substance for conventional therapies to treat obesity and its complications.

Pluripotency of Male Germline Stem Cells

김성태,Juan Carlos Izpisua Belmonte 한국분자세포생물학회 2011 Molecules and cells Vol.32 No.2

The ethical issues and public concerns regarding the use of embryonic stem (ES) cells in human therapy have motivated considerable research into the generation of pluripotent stem cell lines from non-embryonic sources. Numerous reports have shown that pluripotent cells can be generated and derived from germline stem cells (GSCs) in mouse and human testes during in vitro cultivation. The gene expression patterns of these cells are similar to those of ES cells and show the typical self-renewal and differentiation patterns of pluripotent cells in vivo and in vitro. However, the mechanisms underlying the spontaneous dedifferentiation of GSCs remain to be elucidated. Studies to identify master regulators in this reprogramming process are of critical importance for understanding the gene regulatory networks that sustain the cellular status of these cells. The results of such studies would provide a theoretical background for the practical use of these cells in regenerative medicine. Such studies would also help elucidate the molecular mechanisms underlying certain diseases, such as testicular germ cell tumors.

Properties of Contact and Bulk Impedances in Hybrid Lead Halide Perovskite Solar Cells Including Inductive Loop Elements

Guerrero, Antonio,Garcia-Belmonte, Germà,Mora-Sero, Ivan,Bisquert, Juan,Kang, Yong Soo,Jacobsson, T. Jesper,Correa-Baena, Juan-Pablo,Hagfeldt, Anders American Chemical Society 2016 The Journal of Physical Chemistry Part C Vol.120 No.15

<P>Impedance spectroscopy offers access to all the different electronic and ionic processes taking place simultaneously in an operating solar cell. To date, its use on perovskite solar cells has been challenging because of the richness of the physical processes occurring within similar time domains. The aim of this work is to understand the general impedance response and propose a general equivalent circuit model that accounts for the different processes and gives access to quantitative analysis. When the electron-selective contacts and the thickness of the perovskite film are systematically modified, it is possible to distinguish between the characteristic impedance signals of the perovskite layer and those arising from the contacts. The study is carried out using mixed organic lead halogen perovskite (FA(0.85)MA(0.15)Pb(I0.85Br0.15)(3)) solar cells with three different electron-selective contacts: SnO2, TiO2, and Nb2O5. The contacts have been deposited by atomic layer deposition (ALD), which provides pinhole-free films and excellent thickness control in the absence of a mesoporous layer to simplify the impedance analysis. It was found that the interfacial impedance has a rich structure that reveals different capacitive processes, serial steps for electron extraction, and a prominent inductive loop related to negative capacitance at intermediate frequencies. Overall, the present report provides insights into the impedance response of perovskite solar cells which enable an understanding of the different electronic and ionic processes taking place during device operation.</P>

Lineage conversion methodologies meet the reprogramming toolbox

Sancho-Martinez, Ignacio,Baek, Sung Hee,Izpisua Belmonte, Juan Carlos Nature Publishing Group, a division of Macmillan P 2012 NATURE CELL BIOLOGY Vol.14 No.9